Strain identifier
BacDive ID: 14750
Type strain: 
Species: Streptococcus pneumoniae
Strain Designation: Jorgensen 262, 262
Strain history: CIP <- 1995, ATCC <- J.H. Jorgensen: strain 262 <- M. Saubolle
NCBI tax ID(s): 1313 (species)
version 8.1 (current version)
General
@ref: 17316
BacDive-ID: 14750
DSM-Number: 24048
keywords: genome sequence, 16S sequence, Bacteria, microaerophile, mesophilic, antibiotic resistance, human pathogen
description: Streptococcus pneumoniae Jorgensen 262 is a microaerophile, mesophilic human pathogen that has multiple antibiotic resistances and was isolated from human sputum, 75-year-old male.
NCBI tax id
- NCBI tax id: 1313
- Matching level: species
strain history
| @ref | history |
|---|---|
| 17316 | <- CCUG; CCUG 33638 <- ATCC; ATCC 49619 <- J. H. Jorgensen; Jorgensen 262 <- M. Saubolle; |
| 121897 | CIP <- 1995, ATCC <- J.H. Jorgensen: strain 262 <- M. Saubolle |
doi: 10.13145/bacdive14750.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacillota
- domain: Bacteria
- phylum: Bacillota
- class: Bacilli
- order: Lactobacillales
- family: Streptococcaceae
- genus: Streptococcus
- species: Streptococcus pneumoniae
- full scientific name: Streptococcus pneumoniae (Klein 1884) Chester 1901 (Approved Lists 1980)
synonyms
@ref synonym 20215 Staphylococcus pneumoniae 20215 Micrococcus pneumoniae
@ref: 17316
domain: Bacteria
phylum: Firmicutes
class: Bacilli
order: Lactobacillales
family: Streptococcaceae
genus: Streptococcus
species: Streptococcus pneumoniae
full scientific name: Streptococcus pneumoniae (Klein 1884) Chester 1901
strain designation: Jorgensen 262, 262
type strain: no
Morphology
cell morphology
| @ref | motility | confidence | gram stain | cell shape |
|---|---|---|---|---|
| 69480 | no | 95.612 | ||
| 69480 | 100 | positive | ||
| 121897 | no | positive | coccus-shaped |
colony morphology
| @ref | type of hemolysis | hemolysis ability | incubation period |
|---|---|---|---|
| 17316 | alpha | 1 | 1-2 days |
| 121897 | 1 |
Culture and growth conditions
culture medium
| @ref | name | growth | link | composition |
|---|---|---|---|---|
| 17316 | TODD-HEWITT MEDIUM (DSMZ Medium 697) | yes | https://mediadive.dsmz.de/medium/697 | Name: TODD-HEWITT MEDIUM (DSMZ Medium 697) Composition: Casein peptone 20.0 g/l Meat infusion 10.0 g/l NaCl 2.0 g/l NaHCO3 2.0 g/l Dextrose 2.0 g/l Na2HPO4 0.4 g/l Distilled water |
| 17316 | TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) | yes | https://mediadive.dsmz.de/medium/92 | Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water |
| 17316 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
| 41690 | MEDIUM 6 - Columbia agar with 10 % horse blood | yes | Distilled water make up to (1000.000 ml);Columbia agar (39.000 g);Horseblood (100.000 ml) | |
| 121897 | CIP Medium 6 | yes | https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=6 |
culture temp
| @ref | growth | type | temperature | range |
|---|---|---|---|---|
| 17316 | positive | growth | 37 | mesophilic |
| 41690 | positive | growth | 37 | mesophilic |
| 121897 | positive | growth | 30-37 | mesophilic |
| 121897 | no | growth | 10 | psychrophilic |
| 121897 | no | growth | 45 | thermophilic |
Physiology and metabolism
oxygen tolerance
| @ref | oxygen tolerance |
|---|---|
| 17316 | microaerophile |
| 121897 | facultative anaerobe |
antibiogram
| @ref | medium | incubation temperature | oxygen condition | Penicillin G | oxacillin | ampicillin | ticarcillin | mezlocillin | cefalotin | cefazolin | cefotaxime | aztreonam | imipenem | tetracycline | chloramphenicol | gentamycin | amikacin | vancomycin | erythromycin | lincomycin | ofloxacin | norfloxacin | colistin | pipemidic acid | nitrofurantoin | bacitracin | polymyxin b | kanamycin | neomycin | doxycycline | ceftriaxone | clindamycin | fosfomycin | moxifloxacin | linezolid | nystatin | quinupristin/dalfopristin | teicoplanin | piperacillin/tazobactam | incubation time |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17316 | M 693 | 37 | microaerophil | 24 | 18 | 30 | 26-28 | 30 | 28 | 28 | 30 | 0 | 34 | 28 | 26-28 | 12 | 0 | 20 | 28 | 22 | 16 | 16 | 0 | 0 | 24 | 22 | 0 | 0 | 0 | 26 | 30 | 26-28 | 10-12 | 24 | 30 | 0 | 20 | 18 | 28-30 | |
| 17316 | M 693 | 37 | microaerophil | 28-30 | 22 | 34-36 | 32 | 32 | 32 | 32 | 36-38 | 0 | 40 | 28-30 | 30 | 0 | 10 | 20-22 | 30 | 26-28 | 16 | 12 | 0 | 0 | 26 | 26 | 0 | 0 | 0 | 28-30 | 34 | 30-32 | 22 | 26 | 32-34 | 0 | 20 | 20 | 30-32 | 1 |
| 17316 | M 693 | 37 | microaerophil | 30-32 | 22 | 34 | 32 | 30-32 | 30-32 | 30-32 | 36-38 | 0 | 40 | 28-30 | 30 | 0 | 10 | 22 | 30 | 26 | 16 | 16 | 0 | 6 | 28 | 26 | 8 | 6 | 0 | 28 | 36 | 30-32 | 26 | 22 | 30 | 0 | 20 | 20 | 32 | 1 |
| 17316 | M 693 | 32-34 | 24 | 38 | 32-34 | 34 | 32-34 | 34 | 38-40 | 0 | 40 | 30 | 30 | 12 | 6 | 22 | 30 | 28 | 16 | 14 | 0 | 0 | 30 | 26 | 0 | 0 | 0 | 30 | 36 | 32-34 | 18 | 24 | 30 | 0 | 20 | 20 | 32-34 | |||
| 17316 | M 693 | 37 | microaerophil | 24 | 18-20 | 30 | 26 | 28-30 | 26 | 26 | 30 | 0 | 32 | 24 | 24-26 | 8 | 12-14 | 18 | 26 | 24 | 16-18 | 12 | 0 | 0 | 22-24 | 20 | 0 | 8-10 | 6 | 22 | 30 | 26 | 20 | 20 | 26-28 | 0 | 20 | 16 | 26-28 | |
| 17316 | M 693 | 37 | microaerophil | 24 | 18-20 | 30 | 26 | 28-30 | 26 | 26 | 30 | 0 | 32 | 24 | 24-26 | 8 | 12-14 | 18 | 26 | 24 | 16-18 | 12 | 0 | 0 | 22-24 | 20 | 0 | 8-10 | 6 | 22 | 30 | 26 | 20 | 20 | 26-28 | 0 | 20 | 16 | 26-28 |
spore formation
| @ref | spore formation | confidence |
|---|---|---|
| 69481 | no | 100 |
| 69480 | no | 99.983 |
halophily
- @ref: 121897
- salt: NaCl
- growth: no
- tested relation: growth
- concentration: 6.5 %
metabolite utilization
| @ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
|---|---|---|---|---|
| 121897 | 4853 | esculin | - | hydrolysis |
| 121897 | 17632 | nitrate | - | reduction |
| 121897 | 16301 | nitrite | - | reduction |
| 68380 | 16199 | urea | - | hydrolysis |
| 68380 | 29016 | arginine | - | hydrolysis |
| 68380 | 16024 | D-mannose | - | fermentation |
| 68380 | 16634 | raffinose | - | fermentation |
| 68380 | 29985 | L-glutamate | - | degradation |
| 68380 | 17632 | nitrate | - | reduction |
| 68380 | 27897 | tryptophan | - | energy source |
| 68381 | 16988 | D-ribose | - | builds acid from |
| 68381 | 16899 | D-mannitol | - | builds acid from |
| 68381 | 30911 | sorbitol | - | builds acid from |
| 68381 | 17716 | lactose | + | builds acid from |
| 68381 | 27082 | trehalose | + | builds acid from |
| 68381 | 30849 | L-arabinose | - | builds acid from |
| 68381 | 18333 | D-arabitol | - | builds acid from |
| 68381 | 40585 | alpha-cyclodextrin | - | builds acid from |
| 68381 | 606565 | hippurate | - | hydrolysis |
| 68381 | 28087 | glycogen | - | builds acid from |
| 68381 | 6731 | melezitose | - | builds acid from |
| 68381 | 16443 | D-tagatose | - | builds acid from |
| 68381 | 16199 | urea | - | hydrolysis |
antibiotic resistance
- @ref: 121897
- ChEBI: 86455
- metabolite: optochin
- is antibiotic: yes
- is sensitive: yes
- is resistant: no
metabolite production
| @ref | Chebi-ID | metabolite | production |
|---|---|---|---|
| 121897 | 35581 | indole | no |
| 68380 | 35581 | indole | no |
| 68381 | 15688 | acetoin | no |
metabolite tests
| @ref | Chebi-ID | metabolite | voges-proskauer-test | indole test |
|---|---|---|---|---|
| 68381 | 15688 | acetoin | - | |
| 68380 | 35581 | indole | - | |
| 121897 | 15688 | acetoin | - |
enzymes
| @ref | value | activity | ec |
|---|---|---|---|
| 17316 | catalase | - | 1.11.1.6 |
| 17316 | cytochrome-c oxidase | - | 1.9.3.1 |
| 68381 | urease | - | 3.5.1.5 |
| 68381 | beta-mannosidase | - | 3.2.1.25 |
| 68381 | glycyl tryptophan arylamidase | + | |
| 68381 | Alanyl-Phenylalanyl-Proline arylamidase | + | |
| 68381 | alpha-galactosidase | + | 3.2.1.22 |
| 68381 | beta-glucuronidase | - | 3.2.1.31 |
| 68381 | beta-glucosidase | - | 3.2.1.21 |
| 68380 | serine arylamidase | + | |
| 68380 | glutamyl-glutamate arylamidase | - | |
| 68380 | histidine arylamidase | - | |
| 68380 | glycin arylamidase | - | |
| 68380 | alanine arylamidase | + | 3.4.11.2 |
| 68380 | tyrosine arylamidase | + | |
| 68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 |
| 68380 | leucine arylamidase | + | 3.4.11.1 |
| 68380 | phenylalanine arylamidase | + | |
| 68380 | leucyl glycin arylamidase | - | 3.4.11.1 |
| 68380 | proline-arylamidase | - | 3.4.11.5 |
| 68380 | L-arginine arylamidase | + | |
| 68380 | alkaline phosphatase | - | 3.1.3.1 |
| 68380 | tryptophan deaminase | - | 4.1.99.1 |
| 68380 | alpha-fucosidase | - | 3.2.1.51 |
| 68380 | glutamate decarboxylase | - | 4.1.1.15 |
| 68380 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 |
| 68380 | beta-glucuronidase | - | 3.2.1.31 |
| 68380 | alpha-arabinosidase | - | 3.2.1.55 |
| 68380 | beta-glucosidase | + | 3.2.1.21 |
| 68380 | alpha-glucosidase | + | 3.2.1.20 |
| 68380 | beta-Galactosidase 6-phosphate | - | |
| 68380 | beta-galactosidase | + | 3.2.1.23 |
| 68380 | alpha-galactosidase | + | 3.2.1.22 |
| 68380 | arginine dihydrolase | - | 3.5.3.6 |
| 68380 | urease | - | 3.5.1.5 |
| 121897 | oxidase | - | |
| 121897 | beta-galactosidase | + | 3.2.1.23 |
| 121897 | alcohol dehydrogenase | - | 1.1.1.1 |
| 121897 | catalase | - | 1.11.1.6 |
| 121897 | lysine decarboxylase | - | 4.1.1.18 |
| 121897 | ornithine decarboxylase | - | 4.1.1.17 |
| 121897 | urease | - | 3.5.1.5 |
| 68382 | alkaline phosphatase | - | 3.1.3.1 |
| 68382 | esterase (C 4) | + | |
| 68382 | esterase lipase (C 8) | + | |
| 68382 | lipase (C 14) | - | |
| 68382 | leucine arylamidase | + | 3.4.11.1 |
| 68382 | valine arylamidase | + | |
| 68382 | cystine arylamidase | - | 3.4.11.3 |
| 68382 | trypsin | - | 3.4.21.4 |
| 68382 | alpha-chymotrypsin | + | 3.4.21.1 |
| 68382 | acid phosphatase | + | 3.1.3.2 |
| 68382 | naphthol-AS-BI-phosphohydrolase | - | |
| 68382 | alpha-galactosidase | + | 3.2.1.22 |
| 68382 | beta-galactosidase | - | 3.2.1.23 |
| 68382 | beta-glucuronidase | - | 3.2.1.31 |
| 68382 | alpha-glucosidase | + | 3.2.1.20 |
| 68382 | beta-glucosidase | - | 3.2.1.21 |
| 68382 | N-acetyl-beta-glucosaminidase | + | 3.2.1.52 |
| 68382 | alpha-mannosidase | - | 3.2.1.24 |
| 68382 | alpha-fucosidase | - | 3.2.1.51 |
API zym
| @ref | Control | Alkaline phosphatase | Esterase | Esterase Lipase | Lipase | Leucine arylamidase | Valine arylamidase | Cystine arylamidase | Trypsin | alpha- Chymotrypsin | Acid phosphatase | Naphthol-AS-BI-phosphohydrolase | alpha- Galactosidase | beta- Galactosidase | beta- Glucuronidase | alpha- Glucosidase | beta- Glucosidase | N-acetyl-beta- glucosaminidase | alpha- Mannosidase | alpha- Fucosidase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 121897 | - | - | + | + | - | + | + | - | - | + | + | - | + | - | - | + | - | + | - | - |
API rID32A
| @ref | URE | ADH Arg | alpha GAL | beta GAL | beta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta NAG | MNE | RAF | GDC | alpha FUC | NIT | IND | PAL | ArgA | ProA | LGA | PheA | LeuA | PyrA | TyrA | AlaA | GlyA | HisA | GGA | SerA |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 51650 | - | - | + | + | - | + | + | - | - | + | - | - | - | - | - | - | - | + | - | - | + | + | - | + | + | - | - | - | + |
API rID32STR
| @ref | ADH Arg | beta GLU | beta GAR | beta GUR | alpha GAL | PAL | RIB | MAN | SOR | LAC | TRE | RAF | SAC | LARA | DARL | CDEX | VP | APPA | beta GAL | PyrA | beta NAG | GTA | HIP | GLYG | PUL | MAL | MEL | MLZ | Mbeta DG | TAG | beta MAN | URE |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 17316 | - | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | - | - | + | + | - | - | + | + | + | - | - | - | - | - |
| 17316 | + | - | + | - | + | + | - | - | - | + | + | + | + | - | - | - | - | + | + | + | + | + | - | - | + | + | + | - | + | - | - | - |
| 17316 | - | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | - | - | + | + | - | - | +/- | +/- | - | - | +/- | - | - | - |
| 17316 | - | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | + | - | + | + | - | - | + | + | - | - | - | - | - | - |
| 17316 | - | - | + | - | + | - | - | - | - | + | + | +/- | +/- | - | - | - | - | + | - | - | + | + | - | - | +/- | +/- | - | - | - | - | - | - |
| 17316 | - | - | + | - | + | +/- | - | - | - | + | + | + | + | - | - | - | - | + | + | + | + | + | - | - | - | - | - | - | - | - | - | - |
| 51650 | - | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | - | + | - | + | - | - | + | + | - | - | + | - | - | - |
| 17316 | +/- | - | + | - | + | - | - | - | - | + | + | + | + | - | - | - | - | + | + | + | + | + | - | - | + | + | - | - | + | - | - | - |
API biotype100
| @ref | GLU | FRU | GAL | TRE | MNE | SBE | MEL | SAC | RAF | MTE | MAL | LAC | LTE | MbGa | MaGa | CEL | GEN | MbGu | ESC | RIB | ARA | XYL | PLE | RHA | FUC | MLZ | DARL | LARL | XLT | DUL | TAG | GLY | INO | MAN | MTL | TUR | SOR | ADO | HBG | LYX | ERY | MDG | 3MDG | SAT | MUC | LTAT | DTAT | MTAT | DMLT | LMLT | CATE | TATE | TTE | CIT | GRT | GAT | 2KG | 5KG | TRY | NAG | GNT | PAC | PAT | pOBE | QAT | GTE | mOBE | BAT | PPAT | CMT | TGE | BET | PCE | ABT | HIN | LAT | CAP | CYT | HIS | SUC | FUM | GRE | GYT | AVT | ETN | TTN | GLN | ITA | 3OBU | APT | GTT | PRO | DALA | LALA | SER | MNT | PROP | TYR | 2KT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 121897 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Isolation, sampling and environmental information
isolation
| @ref | sample type | geographic location | country | origin.country | continent | latitude | longitude |
|---|---|---|---|---|---|---|---|
| 17316 | human sputum, 75-year-old male | Arizona, Phoenix | USA | USA | North America | 33.4484 | -112.074 |
| 51650 | Human sputum,75-year-old male | Arizona,Phoenix | USA | USA | North America | ||
| 121897 | Human, Sputum | Phoenix, Arizona | United States of America | USA | North America |
isolation source categories
| Cat1 | Cat2 | Cat3 |
|---|---|---|
| #Host | #Human | #Male |
| #Host Body Product | #Fluids | #Sputum |
taxonmaps
- @ref: 69479
- File name: preview.99_4.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_4;96_4;97_4;98_4;99_4&stattab=map
- Last taxonomy: Streptococcus
- 16S sequence: EU156773
- Sequence Identity:
- Total samples: 59292
- soil counts: 819
- aquatic counts: 1515
- animal counts: 56551
- plant counts: 407
Safety information
risk assessment
| @ref | pathogenicity human | pathogenicity animal | biosafety level | biosafety level comment |
|---|---|---|---|---|
| 17316 | yes | yes | 2 | Risk group (German classification) |
| 121897 | 2 | Risk group (French classification) |
Sequence information
16S sequences
| @ref | description | accession | length | database | NCBI tax ID |
|---|---|---|---|---|---|
| 20218 | Streptococcus pneumoniae ATCC 49619 16S ribosomal RNA gene, partial sequence | AY281082 | 1428 | ena | 1313 |
| 20218 | Streptococcus pneumoniae strain ATCC 49619 16S ribosomal RNA gene, partial sequence; and 16S-23S ribosomal RNA intergenic spacer, complete sequence | AY347558 | 372 | ena | 1313 |
| 20218 | Streptococcus pneumoniae strain ATCC 49619 16S ribosomal RNA gene, partial sequence | EU156773 | 1329 | ena | 1313 |
| 20218 | Streptococcus pneumoniae strain ATCC 49619 16S-23S ribosomal RNA intergenic spacer, partial sequence | EU860321 | 248 | ena | 1313 |
Genome sequences
| @ref | description | accession | assembly level | database | NCBI tax ID |
|---|---|---|---|---|---|
| 66792 | Streptococcus pneumoniae ATCC 49619 | GCA_003966485 | complete | ncbi | 1313 |
| 66792 | Streptococcus pneumoniae strain ATCC 49619 | 1313.16298 | complete | patric | 1313 |
Genome-based predictions
predictions
| trait | prediction | confidence | training_data |
|---|---|---|---|
| spore-forming | no | 100 | no |
| motile | no | 93.868 | no |
| flagellated | no | 95.878 | no |
| gram-positive | yes | 93.627 | no |
| anaerobic | no | 93.074 | no |
| aerobic | no | 95.596 | no |
| halophile | yes | 74.844 | no |
| spore-forming | no | 92.2 | no |
| glucose-util | yes | 85.778 | no |
| thermophile | no | 98.99 | no |
| glucose-ferment | yes | 84.666 | no |
External links
@ref: 17316
culture collection no.: DSM 24048, ATCC 49619, CCM 4501, CCUG 33638, DSM 11967, LMG 15155, CIP 104340, NCTC 12977
straininfo link
- @ref: 83867
- straininfo: 7827
literature
| topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
|---|---|---|---|---|---|---|---|---|
| Pathogenicity | 1572984 | Multicenter evaluation of the use of Haemophilus test medium for broth microdilution antimicrobial susceptibility testing of Streptococcus pneumoniae and development of quality control limits. | Jorgensen JH, Doern GV, Ferraro MJ, Knapp CC, Swenson JM, Washington JA | J Clin Microbiol | 10.1128/jcm.30.4.961-966.1992 | 1992 | Culture Media, Evaluation Studies as Topic, Haemophilus, Humans, Microbial Sensitivity Tests/*methods/standards/statistics & numerical data, Quality Control, Reproducibility of Results, Streptococcus pneumoniae/*drug effects | Cultivation |
| Pathogenicity | 7814481 | Development of interpretive criteria and quality control limits for broth microdilution and disk diffusion antimicrobial susceptibility testing of Streptococcus pneumoniae. | Jorgensen JH, Swenson JM, Tenover FC, Ferraro MJ, Hindler JA, Murray PR | J Clin Microbiol | 10.1128/jcm.32.10.2448-2459.1994 | 1994 | Diffusion, Microbial Sensitivity Tests/*standards, Quality Control, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 8501225 | Testing of Streptococcus pneumoniae for resistance to penicillin. | Marshall KJ, Musher DM, Watson D, Mason EO Jr | J Clin Microbiol | 10.1128/jcm.31.5.1246-1250.1993 | 1993 | Culture Media, Evaluation Studies as Topic, Humans, Microbial Sensitivity Tests/*methods, Oxacillin/pharmacology, *Penicillin Resistance, Streptococcus pneumoniae/*drug effects | Cultivation |
| Pathogenicity | 8626258 | Tests for susceptibility of Streptococcus pneumoniae to cefdinir: proposed interpretive criteria and quality control parameters for both microdilution and disc diffusion methods. | Fuchs PC, Barry AL, Tenover FC, Allen SD, Jorgensen JH, Murray PR | J Antimicrob Chemother | 10.1093/jac/36.5.781 | 1995 | Cefdinir, Cephalosporins/*therapeutic use, Microbial Sensitivity Tests, Quality Control, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 8707749 | In-vitro susceptibility of Streptococcus pneumoniae to the d- and l-isomers of ofloxacin: interpretive criteria and quality control limits. | Barry AL, Fuchs PC, Allen SD, Brown SD, Jorgensen JH, Tenover FC | J Antimicrob Chemother | 10.1093/jac/37.2.365 | 1996 | Anti-Infective Agents/*pharmacology, Data Interpretation, Statistical, *Levofloxacin, Microbial Sensitivity Tests, Ofloxacin/*pharmacology, Quality Control, Reproducibility of Results, Stereoisomerism, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 8735115 | Discrepancies between results by E-test and standard microbroth dilution testing of Streptococcus pneumoniae for susceptibility to vancomycin. | Hashemi FB, Schutze GE, Mason EO Jr | J Clin Microbiol | 10.1128/jcm.34.6.1546-1547.1996 | 1996 | Anti-Bacterial Agents/*pharmacology, Child, Drug Resistance, Microbial, Evaluation Studies as Topic, Humans, Microbial Sensitivity Tests/*methods/standards, Pneumococcal Infections/drug therapy/microbiology, Reference Standards, Streptococcus pneumoniae/*drug effects/isolation & purification, Vancomycin/*pharmacology | Enzymology |
| Pathogenicity | 8897164 | Development of interpretive criteria and quality control limits for macrolide and clindamycin susceptibility testing of Streptococcus pneumoniae. | Jorgensen JH, Swenson JM, Tenover FC, Barry A, Ferraro MJ, Murray PR, Reller LB | J Clin Microbiol | 10.1128/jcm.34.11.2679-2684.1996 | 1996 | Anti-Bacterial Agents/*pharmacology, Clindamycin/*pharmacology, Drug Resistance, Microbial, Erythromycin/pharmacology, Humans, Microbial Sensitivity Tests/*methods/*standards, Pneumococcal Infections/drug therapy/microbiology, Quality Control, Streptococcus pneumoniae/*drug effects/isolation & purification | Enzymology |
| Pathogenicity | 8968893 | Interpretive criteria and quality control parameters for testing of susceptibilities of Haemophilus influenzae and Streptococcus pneumoniae to trimethoprim and trimethoprim-sulfamethoxazole. The Antimicrobial Susceptibility Testing OC Group. | Fuchs PC, Barry AL, Brown SD | J Clin Microbiol | 10.1128/jcm.35.1.125-131.1997 | 1997 | Anti-Bacterial Agents/*pharmacology, Haemophilus influenzae/*drug effects, Streptococcus pneumoniae/*drug effects, Trimethoprim/*pharmacology, *Trimethoprim Resistance, Trimethoprim, Sulfamethoxazole Drug Combination/*pharmacology | |
| Pathogenicity | 9218915 | Reproducibility of broth microdilution and disk diffusion susceptibility tests of nine antimicrobial agents against Streptococcus pneumoniae ATCC 49619. | Fuchs PC, Barry AL, Brown SD, Allen SD, Bauman M, Jorgensen JH, Tenover FC | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(97)89155-9 | 1997 | Anti-Bacterial Agents/*pharmacology, *Microbial Sensitivity Tests/methods/standards, Reproducibility of Results, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 9228483 | Comparison of agar dilution, broth dilution, disk diffusion, and the E-test for susceptibility testing of penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. | Thorvilson J, Kohner P, Henry N, Cockerill F 3rd | Eur J Clin Microbiol Infect Dis | 10.1007/BF01726371 | 1997 | *Bacteriological Techniques, Culture Media, Humans, Microbial Sensitivity Tests, *Penicillin Resistance, Penicillins/pharmacology, Sensitivity and Specificity, Species Specificity, Streptococcus pneumoniae/classification/*drug effects | Phylogeny |
| Phylogeny | 9294704 | In vitro antimicrobial activity and MIC quality control guidelines of RPR 106972 (RPR 112808/RPR106950): a novel orally administered streptogramin combination. The Quality Control Study Group. | Putnam SD, Jones RN, Johnson DM | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(97)00023-0 | 1997 | Administration, Oral, Anti-Bacterial Agents/*pharmacology, Drug Combinations, Drug Resistance, Microbial, Enterococcus/drug effects/isolation & purification, Gram-Negative Bacteria/drug effects/isolation & purification, Gram-Positive Cocci/*drug effects/isolation & purification, Guidelines as Topic, Humans, Microbial Sensitivity Tests/standards, Quality Control, Species Specificity, Virginiamycin/pharmacology | Pathogenicity |
| Pathogenicity | 9324186 | Microbiologic effect of bovine cerebrospinal fluid and azithromycin against Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. | Destache CJ, Pakiz CB, Kersting K | Pharmacotherapy | 1997 | Animals, Anti-Bacterial Agents/*pharmacology, Azithromycin/*pharmacology, Cattle, Cerebrospinal Fluid/*microbiology, Haemophilus influenzae/*drug effects, Kinetics, Microbial Sensitivity Tests, Neisseria meningitidis/*drug effects, Streptococcus pneumoniae/*drug effects | Enzymology | |
| Pathogenicity | 9665303 | Provisional quality control parameters and interpretive criteria for testing susceptibility of Streptococcus pneumoniae and Haemophilus influenzae to quinupristin/dalfopristin (RP59500). Antimicrobial Testing Quality Control Group. | Fuchs P, Barry A, Brown S | Eur J Clin Microbiol Infect Dis | 10.1007/BF01691118 | 1998 | Anti-Bacterial Agents/administration & dosage/*pharmacology, Drug Combinations, Haemophilus influenzae/*drug effects, Microbial Sensitivity Tests/*standards, Quality Control, Streptococcus pneumoniae/*drug effects, Virginiamycin/administration & dosage/*analogs & derivatives/pharmacology | |
| Pathogenicity | 9821924 | A mouse model of acute bacterial rhinosinusitis. | Bomer K, Brichta A, Baroody F, Boonlayangoor S, Li X, Naclerio RM | Arch Otolaryngol Head Neck Surg | 10.1001/archotol.124.11.1227 | 1998 | Animals, Disease Models, Animal, Female, Humans, Mice, Mice, Inbred C57BL, Neutrophils/pathology, Nose/pathology, Paranasal Sinuses/pathology, Pneumococcal Infections/*microbiology, Rhinitis/*microbiology/pathology, Sinusitis/*microbiology/pathology, Streptococcus pneumoniae | |
| Pathogenicity | 9925527 | Activities of newer fluoroquinolones against Streptococcus pneumoniae clinical isolates including those with mutations in the gyrA, parC, and parE loci. | Jorgensen JH, Weigel LM, Ferraro MJ, Swenson JM, Tenover FC | Antimicrob Agents Chemother | 10.1128/AAC.43.2.329 | 1999 | Anti-Infective Agents/*pharmacology, Bacterial Proteins/*genetics/metabolism, DNA Gyrase, DNA Topoisomerase IV, DNA Topoisomerases, Type II/genetics, DNA-Binding Proteins/genetics, Drug Resistance, Microbial/genetics, Humans, *Levofloxacin, Microbial Sensitivity Tests, Molecular Sequence Data, Mutation, Ofloxacin/*pharmacology, Streptococcus pneumoniae/*drug effects/genetics/isolation & purification | Genetics |
| Pathogenicity | 9990471 | Antimicrobial activity of SCH27899 (Ziracin), a novel everninomicin derivative, tested against Streptococcus spp.: disk diffusion/etest method evaluations and quality control guidelines. The Quality Control Study Group. | Marshall SA, Jones RN, Erwin ME | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(98)00105-9 | 1999 | *Aminoglycosides, Anti-Bacterial Agents/*pharmacology, Evaluation Studies as Topic, Guidelines as Topic, Humans, Microbial Sensitivity Tests, Quality Control, Streptococcus/*drug effects | |
| Pathogenicity | 10091031 | Anti-streptococcal activity of SB-265805 (LB20304), a novel fluoronaphthyridone, compared with five other compounds, including quality control guidelines. | Johnson DM, Jones RN, Erwin ME | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(98)00104-7 | 1999 | Anti-Infective Agents/chemistry/*pharmacology, *Fluoroquinolones, Gemifloxacin, Guidelines as Topic, Humans, Molecular Structure, Naphthyridines/chemistry/*pharmacology, Penicillins/*pharmacology, Quality Control, Streptococcus/*drug effects | |
| Pathogenicity | 10354857 | Comparative antimicrobial activity of gatifloxacin tested against Streptococcus spp. including quality control guidelines and etest method validation. Quality Control Study Group. | Jones RN, Johnson DM, Erwin ME, Beach ML, Biedenbach DJ, Pfaller MA | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(98)00085-6 | 1999 | Anti-Infective Agents/*pharmacology, *Fluoroquinolones, Gatifloxacin, Humans, Microbial Sensitivity Tests/*standards, Penicillins/pharmacology, Quality Control, Reference Standards, Reproducibility of Results, Streptococcal Infections/microbiology, Streptococcus/*drug effects, Streptococcus pneumoniae/drug effects | |
| Pathogenicity | 10618141 | Quality control guidelines for disk diffusion and broth microdilution antimicrobial susceptibility tests with seven drugs for veterinary applications. | Odland BA, Erwin ME, Jones RN | J Clin Microbiol | 10.1128/JCM.38.1.453-455.2000 | 2000 | Aminoglycosides, Anti-Bacterial Agents/*pharmacology, Fluoroquinolones, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Macrolides, Microbial Sensitivity Tests/standards/*veterinary, Quality Control | |
| Cultivation | 10929879 | Evaluation of quinupristin/dalfopristin (Synercid) and RPR 106972 stability in susceptibility testing media. | Marshall SA, Kugler KC, Jones RN | Int J Antimicrob Agents | 10.1016/s0924-8579(00)00180-1 | 2000 | Anti-Bacterial Agents/*pharmacology, Culture Media, Drug Therapy, Combination/*pharmacology, *Microbial Sensitivity Tests, Virginiamycin/*pharmacology | |
| Pathogenicity | 10953844 | Bactrim reduces the inflammatory response in a murine model of acute rhinosinusitis. | Won YS, Brichta A, Baroody F, Boonlayangoor S, Naclerio R | Rhinology | 2000 | Animals, *Disease Models, Animal, Inflammation/drug therapy, Leukocyte Count, Mice, Neutrophils, Rhinitis/*drug therapy/immunology/microbiology, Sinusitis/*drug therapy/immunology/microbiology, Streptococcal Infections/*drug therapy/microbiology, Streptococcus pneumoniae/growth & development, Trimethoprim, Sulfamethoxazole Drug Combination/*therapeutic use | ||
| Pathogenicity | 11136778 | Ability of laboratories to detect emerging antimicrobial resistance: proficiency testing and quality control results from the World Health Organization's external quality assurance system for antimicrobial susceptibility testing. | Tenover FC, Mohammed MJ, Stelling J, O'Brien T, Williams R | J Clin Microbiol | 10.1128/JCM.39.1.241-250.2001 | 2001 | Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Bacterial Infections/microbiology, *Drug Resistance, Microbial, Humans, *Laboratories/standards, Microbial Sensitivity Tests/*methods/*standards, *Microbiology, Quality Control, *World Health Organization | |
| Pathogenicity | 11418522 | Interpretative criteria and quality control parameters for telithromycin disc diffusion susceptibility tests. | Barry AL, Fuchs PC, Brown SD | J Antimicrob Chemother | 10.1093/jac/48.1.121 | 2001 | Anti-Bacterial Agents/*pharmacology, Diffusion, *Ketolides, *Macrolides, Microbial Sensitivity Tests, Quality Control, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects | |
| Pathogenicity | 11448567 | Validation of cefditoren MIC quality control ranges by a multi-laboratory study (2001). | Jones RN, Biedenbach DJ | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(01)00236-x | 2001 | Cephalosporins/*pharmacology, Escherichia coli/*drug effects, Haemophilus influenzae/*drug effects, Humans, Laboratories/*standards, Microbial Sensitivity Tests/standards, Microbiology, Quality Control, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Enzymology | 11502510 | Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB. | Margolis P, Hackbarth C, Lopez S, Maniar M, Wang W, Yuan Z, White R, Trias J | Antimicrob Agents Chemother | 10.1128/AAC.45.9.2432-2435.2001 | 2001 | *Amidohydrolases, Amino Acid Sequence, Aminopeptidases/*antagonists & inhibitors/genetics/metabolism, Anti-Bacterial Agents/*pharmacology, Drug Resistance, Microbial, Enzyme Inhibitors/*pharmacology, Escherichia coli/drug effects/enzymology, Hydroxamic Acids/*pharmacology, Microbial Sensitivity Tests, Molecular Sequence Data, Mutation, Sequence Homology, Amino Acid, Streptococcus pneumoniae/*drug effects/enzymology | Pathogenicity |
| Pathogenicity | 11570902 | Method preferences and test accuracy of antimicrobial susceptibility testing: updates from the College of Amercian Pathologists Microbiology Surveys Program. | Jones RN | Arch Pathol Lab Med | 10.5858/2001-125-1285-MPATAO | 2001 | Anti-Bacterial Agents/administration & dosage/pharmacology, Data Collection, Escherichia coli/drug effects/growth & development, Humans, Laboratories/*standards, Microbial Sensitivity Tests/*methods/*standards, Penicillins/administration & dosage/pharmacology, Pseudomonas/drug effects/growth & development, *Quality Control, Reproducibility of Results, Sensitivity and Specificity, Streptococcus pneumoniae/drug effects/growth & development | |
| Pathogenicity | 11777665 | Assessment of BMS284756 MIC and 5-microg disk diffusion quality control studies tested against seven American type culture collection strains. | Biedenbach DJ, Jones RN | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(01)00294-2 | 2001 | Anti-Infective Agents/chemistry/*pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, *Fluoroquinolones, Haemophilus influenzae/drug effects, *Indoles, Microbial Sensitivity Tests, Molecular Structure, Pseudomonas aeruginosa/drug effects, Quality Control, *Quinolones, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects | |
| Enzymology | 11821174 | Influence of CO(2) incubation on quinolone activity against Streptococcus pneumoniae and Haemophilus influenzae. | Bolmstrom A, Karlsson A | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(01)00338-8 | 2002 | 4-Quinolones, Anti-Infective Agents/*pharmacology, *Carbon Dioxide, Haemophilus influenzae/*drug effects/isolation & purification, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Streptococcus pneumoniae/*drug effects/isolation & purification | Phylogeny |
| Pathogenicity | 12573554 | Determination of disk diffusion and MIC quality control parameters for AZD2563, a novel long-acting oxazolidinone. | Anderegg TR, Jones RN | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(02)00482-0 | 2003 | Diffusion, Drug Resistance, Microbial, Enterococcus faecalis/drug effects/isolation & purification, Gram-Positive Bacteria/*drug effects/isolation & purification, Humans, Microbial Sensitivity Tests/*methods, Oxazolidinones/*pharmacology, Quality Control, Sensitivity and Specificity, Staphylococcus aureus/drug effects/isolation & purification, Streptococcus pneumoniae/drug effects/isolation & purification | Enzymology |
| Metabolism | 12615869 | Experimental pneumococcal pleural empyema model: the effect of moxifloxacin. | Strahilevitz J, Lev A, Levi I, Fridman E, Rubinstein E | J Antimicrob Chemother | 10.1093/jac/dkg094 | 2003 | Animals, Anti-Infective Agents/metabolism/*therapeutic use, *Aza Compounds, *Disease Models, Animal, Empyema, Pleural/*drug therapy/metabolism, *Fluoroquinolones, Male, Moxifloxacin, Pleura/drug effects, Pneumococcal Infections/*drug therapy/metabolism, *Quinolines, Rabbits, Turpentine/toxicity | Pathogenicity |
| Pathogenicity | 12812719 | Re-evaluation of quality control guidelines for gatifloxacin and garenoxacin (BMS284756) when susceptibility testing Haemophilus influenzae and Streptococcus pneumoniae. | Anderegg TR, Biedenbach DJ, Jones RN | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(03)00039-7 | 2003 | Anti-Infective Agents/*pharmacology, Drug Resistance, Bacterial, *Fluoroquinolones, Gatifloxacin, Guidelines as Topic, Haemophilus influenzae/*drug effects/isolation & purification, Humans, Indoles/*pharmacology, Microbial Sensitivity Tests/*standards, Quality Control, Quinolones/*pharmacology, Sensitivity and Specificity, Streptococcus pneumoniae/*drug effects/isolation & purification | Enzymology |
| Pathogenicity | 12867099 | Antagonism between penicillin and erythromycin against Streptococcus pneumoniae: does it exist? | Deshpande LM, Jones RN | Diagn Microbiol Infect Dis | 10.1016/s0732-8893(03)00050-6 | 2003 | Animals, Drug Resistance, Microbial, Drug Therapy, Combination, Erythromycin/*antagonists & inhibitors/pharmacology, Female, Mice, Microbial Sensitivity Tests, Penicillins/*antagonists & inhibitors/pharmacology, Pneumococcal Infections/drug therapy, Streptococcus pneumoniae/*drug effects/metabolism | Metabolism |
| Cultivation | 12878526 | Activities of mutant prevention concentration-targeted moxifloxacin and levofloxacin against Streptococcus pneumoniae in an in vitro pharmacodynamic model. | Allen GP, Kaatz GW, Rybak MJ | Antimicrob Agents Chemother | 10.1128/AAC.47.8.2606-2614.2003 | 2003 | Anti-Infective Agents/*pharmacology, Area Under Curve, *Aza Compounds, Culture Media, DNA Gyrase/genetics/metabolism, DNA Topoisomerase IV/genetics, DNA, Bacterial/genetics, Drug Resistance, Bacterial, *Fluoroquinolones, *Levofloxacin, Microbial Sensitivity Tests, Models, Biological, Moxifloxacin, Mutation/*genetics, Ofloxacin/*pharmacology, *Quinolines, Reverse Transcriptase Polymerase Chain Reaction, Streptococcus pneumoniae/*drug effects/*genetics | Metabolism |
| Enzymology | 12951352 | Emergence of resistant Streptococcus pneumoniae in an in vitro dynamic model that simulates moxifloxacin concentrations inside and outside the mutant selection window: related changes in susceptibility, resistance frequency and bacterial killing. | Zinner SH, Lubenko IY, Gilbert D, Simmons K, Zhao X, Drlica K, Firsov AA | J Antimicrob Chemother | 10.1093/jac/dkg401 | 2003 | Area Under Curve, Aza Compounds/pharmacokinetics/*pharmacology, Dose-Response Relationship, Drug, Drug Resistance, Bacterial/*drug effects/physiology, Fluoroquinolones, Microbial Sensitivity Tests/methods, *Models, Biological, Moxifloxacin, *Mutation, Quinolines/pharmacokinetics/*pharmacology, Streptococcus pneumoniae/*drug effects/*growth & development/metabolism | Pathogenicity |
| Pathogenicity | 14761722 | Disk diffusion quality control guidelines for NVP-PDF 713: a novel peptide deformylase inhibitor. | Anderegg TR, Jones RN | Diagn Microbiol Infect Dis | 10.1016/S0732-8893(03)00162-7 | 2004 | Amidohydrolases/*antagonists & inhibitors/*pharmacology, Culture Media, Diffusion, Gram-Negative Bacteria/*drug effects/growth & development, Gram-Positive Bacteria/*drug effects/growth & development, Guidelines as Topic, Humans, Microbial Sensitivity Tests, Quality Control, Sensitivity and Specificity | Cultivation |
| Pathogenicity | 15330320 | An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae. | Bantar C, Nicola F, Arenoso H, Soutric J, Caruso N, Fernandez Canigia L | J Chemother | 10.1179/joc.2004.16.3.248 | 2004 | Adult, Amoxicillin/blood/*pharmacology, Analysis of Variance, Azithromycin/blood/*pharmacology, Blood Bactericidal Activity, Colony Count, Microbial, Cross-Over Studies, Doxycycline/blood/*pharmacology, Drug Resistance, Bacterial, Drug Therapy, Combination/therapeutic use, Female, Humans, *Levofloxacin, Male, Microbial Sensitivity Tests, Middle Aged, Ofloxacin/blood/*pharmacology, Probability, Sensitivity and Specificity, Serum Bactericidal Test, Single-Blind Method, Statistics, Nonparametric, Streptococcus pneumoniae/*drug effects/isolation & purification, Sulbactam/blood/*pharmacology | Enzymology |
| Pathogenicity | 15769331 | [Study on the molecular epidemiology of beta-lactamase TEM gene in isolated Streptococcus pneumoniae]. | Ding YF, Zhang JH, Mi ZH, Qin L, Tao YZ, Qi X | Zhonghua Liu Xing Bing Xue Za Zhi | 2004 | Base Sequence, China/epidemiology, Drug Resistance, Bacterial/genetics, Female, Genes, Bacterial/*genetics, Humans, Male, Molecular Epidemiology, Molecular Sequence Data, Pneumonia, Bacterial/*epidemiology/genetics/microbiology, Point Mutation, Streptococcus pneumoniae/*enzymology/genetics, beta-Lactam Resistance, beta-Lactamases/*genetics | Genetics | |
| Pathogenicity | 15848296 | Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model. | Firsov AA, Alferova IV, Smirnova MV, Lubenko IY, Portnoy YA, Zinner SH | Int J Antimicrob Agents | 10.1016/j.ijantimicag.2005.02.004 | 2005 | Anti-Bacterial Agents/*pharmacology, Area Under Curve, Ciprofloxacin/pharmacology, Computer Simulation, Dose-Response Relationship, Drug, Drug Resistance, Bacterial/genetics, Fluoroquinolones, Humans, *Levofloxacin, Microbial Sensitivity Tests/methods, Ofloxacin/*pharmacology, Quinolones/*pharmacology, Streptococcus pneumoniae/*drug effects/genetics/isolation & purification, Time Factors | Enzymology |
| Pathogenicity | 15890718 | Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin. | Bouchillon SK, Johnson JL, Hoban DJ, Stevens TM, Johnson BM | J Antimicrob Chemother | 10.1093/jac/dki156 | 2005 | Anti-Bacterial Agents/*pharmacology, Azithromycin/*pharmacology, Carbon Dioxide/*pharmacology, Haemophilus influenzae/*drug effects, Humans, Ketolides/*pharmacology, Microbial Sensitivity Tests, Streptococcus pneumoniae/*drug effects, Streptococcus pyogenes/*drug effects | |
| Pathogenicity | 16185457 | [Study on drug resistance and molecular epidemiology of Streptococcus pneumoniae isolated in Chongqing]. | Yao C, Yu ZB, Xiao YH | Zhonghua Liu Xing Bing Xue Za Zhi | 2005 | China/epidemiology, Clindamycin/pharmacology, DNA, Bacterial/*genetics, Drug Resistance, Bacterial/*genetics, Humans, Macrolides/pharmacology, Microbial Sensitivity Tests, Molecular Epidemiology, Pneumococcal Infections/*epidemiology/microbiology, Prevalence, Streptococcus pneumoniae/drug effects/*genetics | ||
| Pathogenicity | 16185459 | [Study on the molecule epidemiological between resistances of 7 genes interrelated 4 antibiotic to isolated Streptococcus pneumoniae in children]. | Ding YF, Mi ZH, Zhang JH, Tao YZ, Qin L | Zhonghua Liu Xing Bing Xue Za Zhi | 2005 | Anti-Bacterial Agents/*pharmacology, Child, China/epidemiology, DNA, Bacterial/genetics, Drug Resistance, Multiple, Bacterial/*genetics, Erythromycin/pharmacology, Female, Humans, Male, Microbial Sensitivity Tests, Molecular Epidemiology, Penicillin Resistance/genetics, Pneumococcal Infections/*epidemiology/microbiology, Streptococcus pneumoniae/*drug effects/*genetics/isolation & purification, Tetracycline Resistance/genetics, Vancomycin/pharmacology | Phylogeny | |
| Pathogenicity | 16369123 | Does cold environment affect Streptococcus pneumoniae adherence to rat buccal epithelium? | Oztuna F, Ozlu T, Bulbul Y, Buruk K, Topbas M | Respiration | 10.1159/000090160 | 2005 | Animals, Bacterial Adhesion/*physiology, Cold Temperature, Humans, Models, Animal, Mouth Mucosa/*microbiology, Pneumonia, Bacterial/microbiology, Rats, Rats, Sprague-Dawley, Streptococcus pneumoniae/isolation & purification/*physiology | Enzymology |
| Enzymology | 16506083 | Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration. | Fukuda Y, Takahata M, Mitsuyama J | J Infect Chemother | 10.1007/s10156-005-0420-0 | 2006 | Anti-Bacterial Agents/*pharmacokinetics/pharmacology, Area Under Curve, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Fluoroquinolones/*pharmacokinetics/pharmacology, Humans, Levofloxacin, Microbial Sensitivity Tests, Models, Biological, Mutation, Naphthyridines/*pharmacokinetics/pharmacology, Ofloxacin/pharmacokinetics/pharmacology, Pneumococcal Infections/*drug therapy, Serum Bactericidal Test, Streptococcus pneumoniae/*drug effects, Treatment Outcome | Pathogenicity |
| Pathogenicity | 16784863 | Synthesis and in vitro antimicrobial studies of medicinally important novel N-alkyl and N-sulfonyl derivatives of 1-[bis(4-fluorophenyl)-methyl]piperazine. | Narendra Sharath Chandra JN, Sadashiva CT, Kavitha CV, Rangappa KS | Bioorg Med Chem | 10.1016/j.bmc.2006.05.064 | 2006 | Alkylation, Anti-Infective Agents/*chemical synthesis/*pharmacology, Bacteria/drug effects, Heterocyclic Compounds/chemistry, Indicator Dilution Techniques, Indicators and Reagents, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Nephelometry and Turbidimetry, Piperazines/*chemical synthesis/*pharmacology, Spectrophotometry, Infrared, Structure-Activity Relationship | |
| Cultivation | 17494717 | Comparative in vitro antimicrobial activity of tigecycline, a new glycylcycline compound, in freshly prepared medium and quality control. | Brown SD, Traczewski MM | J Clin Microbiol | 10.1128/JCM.02351-06 | 2007 | Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects, Culture Media, Drug Resistance, Bacterial, Microbial Sensitivity Tests, Minocycline/*analogs & derivatives/pharmacology, Quality Control, Tetracycline/*pharmacology, Tigecycline | Pathogenicity |
| Pathogenicity | 17670919 | Factors influencing broth microdilution antimicrobial susceptibility test results for dalbavancin, a new glycopeptide agent. | Rennie RP, Koeth L, Jones RN, Fritsche TR, Knapp CC, Killian SB, Goldstein BP | J Clin Microbiol | 10.1128/JCM.02411-06 | 2007 | Anti-Bacterial Agents/*pharmacology, Humans, Microbial Sensitivity Tests/*methods, Staphylococcus aureus/drug effects, Streptococcus/drug effects, Teicoplanin/*analogs & derivatives/pharmacology | |
| Enzymology | 17822333 | [Species-identification and antimicrobial susceptibility tests by the fully automated RAISUS using an early-harvested cell suspension]. | Nakasone I, Kisanuki K, Higa M, Kinjo T, Yamane N | Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi | 2006 | Automation, Bacteriological Techniques/*instrumentation, Enterococcus faecalis/isolation & purification, Escherichia coli/isolation & purification, Microbial Sensitivity Tests/*instrumentation, Pseudomonas aeruginosa, Staphylococcus aureus/isolation & purification, Streptococcus pneumoniae/isolation & purification | Phylogeny | |
| Enzymology | 18073455 | Streptococcus pneumoniae adherence in rats under different degrees and durations of cigarette smoke. | Ozlu T, Celik I, Oztuna F, Bulbul Y, Ozsu S | Respiration | 10.1159/000112472 | 2007 | Animals, Bacterial Adhesion/*physiology, Epithelial Cells, Models, Animal, Mouth Mucosa/cytology/*microbiology, Rats, Rats, Sprague-Dawley, *Smoke, Smoking/adverse effects, Streptococcus pneumoniae/isolation & purification/*physiology, Time Factors, *Tobacco | Phylogeny |
| Pathogenicity | 18614315 | Newly defined in vitro quality control ranges for oritavancin broth microdilution testing and impact of variation in testing parameters. | Arhin FF, Tomfohrde K, Draghi DC, Aranza M, Parr TR Jr, Sahm DF, Moeck G | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2008.05.009 | 2008 | Anti-Bacterial Agents/*pharmacology, Enterococcus faecalis/*drug effects, Glycopeptides/*pharmacology, Humans, Lipoglycopeptides, Microbial Sensitivity Tests/methods/*standards, Polysorbates, Quality Control, Reference Standards, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 18853314 | Different application volumes of ethyl-cyanoacrylate tissue adhesive can change its antibacterial effects against ocular pathogens in vitro. | Romero IL, Paiato TP, Silva CB, Nigro JB, Malta S, Jenne Mimica LM, Soong HK, Hida RY | Curr Eye Res | 10.1080/02713680802437692 | 2008 | Anti-Bacterial Agents/*administration & dosage, Bacteria/*drug effects, Cyanoacrylates/*administration & dosage, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects, Tissue Adhesives/*administration & dosage | |
| Pathogenicity | 20060624 | Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4,6-pyrimidinediones. | Tomasic T, Zidar N, Mueller-Premru M, Kikelj D, Masic LP | Eur J Med Chem | 10.1016/j.ejmech.2009.12.030 | 2009 | Anti-Bacterial Agents/*chemical synthesis/*pharmacology, Bacteria/drug effects/growth & development, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Pyrimidines/*chemical synthesis/*pharmacology, Spectrometry, Mass, Electrospray Ionization, Spectrophotometry, Infrared, Thiazolidines/*chemical synthesis/*pharmacology | |
| Pathogenicity | 20803622 | Synthesis and antibacterial activity of novel 4''-O-carbamoyl erythromycin-A derivatives. | Qi Y, Jiao B, Ma X, Cui W, Ma S | Arch Pharm (Weinheim) | 10.1002/ardp.200900288 | 2010 | Anti-Bacterial Agents/*chemical synthesis/pharmacology, Drug Resistance, Bacterial/drug effects, Erythromycin/*analogs & derivatives/chemical synthesis/pharmacology, Microbial Sensitivity Tests, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects, Streptococcus pyogenes/drug effects | |
| Metabolism | 21192991 | Olfactory ensheathing cells as putative host cells for Streptococcus pneumoniae: evidence of bacterial invasion via mannose receptor-mediated endocytosis. | Macedo-Ramos H, Campos FS, Carvalho LA, Ramos IB, Teixeira LM, De Souza W, Cavalcante LA, Baetas-da-Cruz W | Neurosci Res | 10.1016/j.neures.2010.12.015 | 2010 | Animals, Bacterial Adhesion/physiology, Endocytosis/*physiology, Host-Parasite Interactions/physiology, Immunoblotting, Immunohistochemistry, Lectins, C-Type/*metabolism, Mannose Receptor, Mannose-Binding Lectins/*metabolism, Neuroglia/immunology/metabolism/*microbiology, Pneumococcal Infections/*metabolism, Rats, Rats, Wistar, Receptors, Cell Surface/*metabolism, Rhinitis/immunology/microbiology, Sinusitis/immunology/microbiology | Pathogenicity |
| Enzymology | 21268582 | Efficient screening of a novel antimicrobial peptide from Jatropha curcas by cell membrane affinity chromatography. | Xiao J, Zhang H, Niu L, Wang X | J Agric Food Chem | 10.1021/jf103876b | 2011 | Amino Acid Sequence, Animals, Antimicrobial Cationic Peptides/chemistry/*isolation & purification/pharmacology, Bacteria/drug effects/ultrastructure, *Cell Membrane, Cell Wall/drug effects, Chromatography, Affinity/*methods, Heart Atria/ultrastructure, Jatropha/*chemistry, Male, Microscopy, Electron, Transmission, Plant Proteins/*isolation & purification, Rats, Rats, Wistar, Spectroscopy, Fourier Transform Infrared | Phylogeny |
| Metabolism | 21524827 | Synthesis and antibacterial activity of novel 4''-O-benzimidazolyl clarithromycin derivatives. | Cong C, Wang H, Hu Y, Liu C, Ma S, Li X, Cao J, Ma S | Eur J Med Chem | 10.1016/j.ejmech.2011.04.004 | 2011 | Anti-Bacterial Agents/*chemical synthesis/pharmacology, Bacterial Proteins/genetics/metabolism, Benzimidazoles/*chemical synthesis/pharmacology, Clarithromycin/analogs & derivatives/*chemical synthesis/pharmacology, Drug Resistance, Bacterial/drug effects/genetics, Erythromycin/pharmacology, Gene Expression, Hydrazines/*chemistry, Membrane Proteins/genetics/metabolism, Methyltransferases/genetics/metabolism, Staphylococcus aureus/*drug effects/genetics/growth & development, Streptococcus pneumoniae/*drug effects/genetics/growth & development, Structure-Activity Relationship | Pathogenicity |
| Phylogeny | 21553481 | [Bacterial strains isolated from systemic infections and reported for evaluation and antibiotic resistance surveillance by the "Dr. Victor Babes" Clinical Hospital for Infectious and Tropical Diseases, Bucharest]. | Nica M, Biolan T, Dascalu A, Mozes E, Toderan A, Calistru P, Ceausu E | Bacteriol Virusol Parazitol Epidemiol | 2010 | Anti-Bacterial Agents/*pharmacology, Bacterial Infections/*drug therapy/epidemiology/*microbiology/prevention & control, Cephalosporins/pharmacology, Ciprofloxacin/pharmacology, *Drug Resistance, Bacterial, Enterococcus faecalis/isolation & purification, Enterococcus faecium/isolation & purification, Erythromycin/pharmacology, Escherichia coli/isolation & purification, European Union, Gentamicins/pharmacology, Hospitals, Isolation, Hospitals, University, Humans, Incidence, *Microbial Sensitivity Tests/methods, Neisseria meningitidis/isolation & purification, Penicillins/pharmacology, Practice Guidelines as Topic, Retrospective Studies, Rifampin/pharmacology, Romania/epidemiology, Sentinel Surveillance, Staphylococcus aureus/isolation & purification, Streptococcus pneumoniae/isolation & purification | Enzymology | |
| Pathogenicity | 21653768 | Determination of disk diffusion and MIC quality control guidelines for JNJ-Q2, a novel quinolone. | Ross JE, Liverman LC, Jones RN | J Clin Microbiol | 10.1128/JCM.00636-11 | 2011 | Anti-Bacterial Agents/*pharmacology, Bacteria/*drug effects, Fluoroquinolones/*pharmacology, Humans, Microbial Sensitivity Tests/standards, Quality Control | |
| 21864700 | In vivo efficacy of KRP-109, a novel elastase inhibitor, in a murine model of severe pneumococcal pneumonia. | Yamada K, Yanagihara K, Araki N, Harada Y, Morinaga Y, Izumikawa K, Kakeya H, Yamamoto Y, Hasegawa H, Kohno S, Kamihira S | Pulm Pharmacol Ther | 10.1016/j.pupt.2011.08.001 | 2011 | Animals, Benzoxazines/pharmacology/*therapeutic use, Bronchoalveolar Lavage Fluid/immunology, Disease Models, Animal, Female, Leukocyte Elastase/*antagonists & inhibitors, Lung/microbiology/pathology, Mice, Mice, Inbred CBA, Pneumonia, Pneumococcal/*drug therapy/microbiology/pathology, Pyrrolidines/pharmacology/*therapeutic use, Serine Proteinase Inhibitors/pharmacology/*therapeutic use | ||
| Pathogenicity | 21918031 | Determination of disk diffusion and MIC quality control ranges for GSK1322322, a novel peptide deformylase inhibitor. | Ross JE, Scangarella-Oman NE, Miller LA, Sader HS, Jones RN | J Clin Microbiol | 10.1128/JCM.01213-11 | 2011 | Amidohydrolases/*antagonists & inhibitors, Anti-Bacterial Agents/*pharmacology, Enzyme Inhibitors/*pharmacology, Haemophilus influenzae/*drug effects, Humans, Microbial Sensitivity Tests/methods, Quality Control, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 21999582 | Synthesis, antimicrobial and antiproliferative activity of novel silver(I) tris(pyrazolyl)methanesulfonate and 1,3,5-triaza-7-phosphadamantane complexes. | Pettinari C, Marchetti F, Lupidi G, Quassinti L, Bramucci M, Petrelli D, Vitali LA, da Silva MF, Martins LM, Smolenski P, Pombeiro AJ | Inorg Chem | 10.1021/ic201714c | 2011 | Adamantane/*analogs & derivatives/chemistry, Animals, Anti-Bacterial Agents/*chemical synthesis/pharmacology, Antineoplastic Agents/*chemical synthesis/pharmacology, Bacterial Infections/drug therapy/microbiology, Candida albicans/drug effects/growth & development, Candidiasis/drug therapy/microbiology, Cattle, Cell Line, Tumor, Chemistry, Pharmaceutical/*methods, Crystallography, X-Ray, DNA/antagonists & inhibitors/chemistry, Disinfectants/*chemical synthesis/pharmacology, Gram-Negative Bacteria/drug effects/growth & development, Gram-Positive Bacteria/drug effects/growth & development, Humans, Magnetic Resonance Spectroscopy, Melanoma/drug therapy/pathology, Mesylates/*chemistry, Microbial Sensitivity Tests, Models, Molecular, Organometallic Compounds/*chemical synthesis/pharmacology, Organophosphorus Compounds/*chemistry, Silver Compounds/*chemistry, Spectrometry, Mass, Electrospray Ionization | |
| Pathogenicity | 22522648 | An Escherichia coli cell membrane chromatography-offline LC-TOF-MS method for screening and identifying antimicrobial peptides from Jatropha curcas meal protein isolate hydrolysates. | Xiao J, Zhang H | J Biomol Screen | 10.1177/1087057112442744 | 2012 | Anti-Infective Agents/chemistry/*isolation & purification/pharmacology, Antimicrobial Cationic Peptides/chemistry/*isolation & purification/pharmacology, Bacillus subtilis/drug effects, Cell Membrane/metabolism, Chromatography, Liquid/*methods, Escherichia coli/drug effects/metabolism/ultrastructure, Jatropha/*chemistry, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Protein Hydrolysates/chemistry, Pseudomonas aeruginosa/drug effects, Sequence Analysis, Protein, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/*methods, Staphylococcus aureus/drug effects, Tandem Mass Spectrometry | Enzymology |
| Pathogenicity | 22760797 | Evaluation of silicon oil on bacterial growth. | Adams F, Romero IL, Silva CB, Manzano RP | Arq Bras Oftalmol | 10.1590/s0004-27492012000200003 | 2012 | Anti-Infective Agents/*pharmacology, Candida albicans/*drug effects/growth & development, Endophthalmitis/*microbiology, Gram-Negative Bacteria/*drug effects/growth & development, Gram-Positive Bacteria/*drug effects/growth & development, Humans, Microbial Sensitivity Tests, Silicone Oils/*pharmacology | |
| Pathogenicity | 22814462 | Disk diffusion and MIC quality control ranges for BC-3205 and BC-3781, two novel pleuromutilin antibiotics. | Ross JE, Sader HS, Ivezic-Schoenfeld Z, Paukner S, Jones RN | J Clin Microbiol | 10.1128/JCM.01294-12 | 2012 | Anti-Bacterial Agents/*pharmacology, Diterpenes/pharmacology, Haemophilus influenzae/*drug effects, Humans, Microbial Sensitivity Tests/standards, Polycyclic Compounds, Quality Control, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 23163534 | Antimicrobial susceptibility testing of Streptococcus pneumoniae and Haemophilus influenzae --internal quality control as a quality tool on a national level. | Karpanoja P, Nissinen A, Huovinen P, Sarkkinen H | APMIS | 10.1111/apm.12021 | 2012 | Amoxicillin-Potassium Clavulanate Combination/pharmacology, Anti-Bacterial Agents/*pharmacology, Azithromycin/pharmacology, Disk Diffusion Antimicrobial Tests/*standards, Finland, Haemophilus influenzae/*drug effects, Quality Control, Reproducibility of Results, Sensitivity and Specificity, Streptococcus pneumoniae/*drug effects, Surveys and Questionnaires | |
| Pathogenicity | 23461830 | Determination of disk diffusion and MIC quality control guidelines for GSK2251052: a novel boron-containing antibacterial. | Ross JE, Scangarella-Oman N, Jones RN | Diagn Microbiol Infect Dis | 10.1016/j.diagmicrobio.2013.01.007 | 2013 | Anti-Bacterial Agents/*pharmacology, Gram-Negative Bacteria/*drug effects, Gram-Positive Bacteria/*drug effects, Humans, Microbial Sensitivity Tests/methods/*standards, *Quality Control | |
| Metabolism | 23683724 | Roles of virulence genes (PsaA and CpsA) on the invasion of Streptococcus pneumoniae into blood system. | Hu DK, Wang DG, Liu Y, Liu CB, Yu LH, Qu Y, Luo XH, Yang JH, Yu J, Zhang J, Li XY | Eur J Med Res | 10.1186/2047-783X-18-14 | 2013 | Adhesins, Bacterial/*genetics, Alveolar Epithelial Cells/cytology/metabolism/pathology, Bacterial Proteins/*genetics, Blood/microbiology, Cell Line, Gene Expression Regulation, Bacterial, Humans, Lipoproteins/*genetics, Monocytes/cytology/metabolism/pathology, Pneumonia, Pneumococcal/blood/*genetics/microbiology/*pathology, Sputum/microbiology, Streptococcus pneumoniae/genetics/*pathogenicity | Pathogenicity |
| Pathogenicity | 23777013 | Rapid bactericidal activity of sitafloxacin against Streptococcus pneumoniae. | Kanda H, Inoue K, Okumura R, Hoshino K | Jpn J Antibiot | 2013 | Anti-Bacterial Agents/*pharmacology, Fluoroquinolones/*pharmacology, Humans, Microbial Sensitivity Tests, Streptococcus pneumoniae/*drug effects | ||
| Pathogenicity | 23812253 | In vitro inflammatory responses elicited by isolates of Alloiococcus otitidis obtained from children with otitis media with effusion. | Ashhurst-Smith C, Hall ST, Burns CJ, Stuart J, Blackwell CC | Innate Immun | 10.1177/1753425913492181 | 2013 | Carnobacteriaceae/drug effects/growth & development/*immunology, Cell Line, Cell Survival/drug effects, Child, Cholecalciferol/pharmacology, Cytokines/biosynthesis, Disinfectants/pharmacology, Formaldehyde/pharmacology, Humans, Inflammation/*pathology, Interferon-gamma/pharmacology, Mycoplasma/chemistry, Otitis Media with Effusion/*microbiology/*pathology, Streptococcal Infections/immunology/microbiology, Streptococcus pneumoniae/immunology, Vitamins/pharmacology | |
| Pathogenicity | 23840817 | Detection of Streptococcus pneumoniae from Different Types of Nasopharyngeal Swabs in Children. | Dube FS, Kaba M, Whittaker E, Zar HJ, Nicol MP | PLoS One | 10.1371/journal.pone.0068097 | 2013 | Bacterial Load, Cellulose, Child, Female, Humans, Infant, Male, Molecular Diagnostic Techniques/*methods, Nasopharynx/*microbiology, Nylons, Pneumococcal Infections/*diagnosis/microbiology, Real-Time Polymerase Chain Reaction, Serogroup, Specimen Handling/*instrumentation/methods, Streptococcus pneumoniae/genetics/growth & development/*isolation & purification | Enzymology |
| Metabolism | 24045590 | Effects of clinical isolates of Streptococcus pneumoniae on THP-1 human monocytic cells. | Zhang J, Hu DK, Wang DG, Liu Y, Liu CB, Yu LH, Qu Y, Luo XH, Yang JH, Yu J, Liu SC, Li XY | Mol Med Rep | 10.3892/mmr.2013.1688 | 2013 | Aminoacyltransferases/genetics, Cells, Cultured, DNA, Bacterial/genetics, Enzyme-Linked Immunosorbent Assay, Humans, Intercellular Adhesion Molecule-1/*metabolism, Interleukin-10/*metabolism, Interleukin-8/*metabolism, Monocytes/*metabolism/microbiology, Penicillin-Binding Proteins/genetics, Pneumonia, Pneumococcal/blood/genetics/*microbiology, Real-Time Polymerase Chain Reaction, Sputum/*metabolism/microbiology, Streptococcus pneumoniae/genetics/*isolation & purification | Pathogenicity |
| Pathogenicity | 24342635 | Antibiotic activity against naive and induced Streptococcus pneumoniae biofilms in an in vitro pharmacodynamic model. | Vandevelde NM, Tulkens PM, Van Bambeke F | Antimicrob Agents Chemother | 10.1128/AAC.01858-13 | 2013 | Anti-Bacterial Agents/*pharmacology, Bacteriological Techniques, Biofilms/*drug effects, Fluorescent Dyes, In Vitro Techniques, Microbial Sensitivity Tests, Models, Biological, Oxazines, Streptococcus pneumoniae/*drug effects, Xanthenes | |
| Phylogeny | 24605655 | [Molecular-genetic and phylogenetic characteristic of Streptococcus pneumoniae strains isolated from patients with meningitis and carriers]. | Aleshkin VA, Karaulov AV, Slobodeniuk VV, Afanas'ev SS, Urban IuN, Voropaeva EA, Afanas'ev MS, Egorova EA, Metel'skaia VA, Aleshkin AV, Grechishnikova OG, Bairakova AL, Nesvizhskii IuV, Rubal'skii EO | Zh Mikrobiol Epidemiol Immunobiol | 2013 | Bacterial Capsules/genetics, Bacterial Proteins/genetics, *Carrier State, Female, Humans, Male, Meningitis, Bacterial/epidemiology/*genetics, *Phylogeny, Pneumococcal Infections/epidemiology/*genetics, Polysaccharides, Bacterial/genetics, Russia/epidemiology, Streptococcus pneumoniae/*genetics/isolation & purification | Pathogenicity | |
| Pathogenicity | 24759716 | Determination of disk diffusion and MIC quality control guidelines for GSK2140944, a novel bacterial type II topoisomerase inhibitor antimicrobial agent. | Ross JE, Scangarella-Oman NE, Flamm RK, Jones RN | J Clin Microbiol | 10.1128/JCM.00656-14 | 2014 | Anti-Infective Agents/*pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Humans, Microbial Sensitivity Tests/*standards, Molecular Structure, Quality Control, Topoisomerase Inhibitors/*pharmacology | |
| Pathogenicity | 24920777 | Quality control MIC ranges used for telavancin with application of a revised CLSI reference broth microdilution method. | Ross JE, Mendes RE, Jones RN | J Clin Microbiol | 10.1128/JCM.01210-14 | 2014 | Aminoglycosides/*pharmacology, Anti-Bacterial Agents/*pharmacology, Enterococcus faecalis/*drug effects, Humans, Lipoglycopeptides, Microbial Sensitivity Tests/methods/standards, Quality Control, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 24931335 | Helichrysum arenarium subsp. arenarium: phenolic composition and antibacterial activity against lower respiratory tract pathogens. | Gradinaru AC, Silion M, Trifan A, Miron A, Aprotosoaie AC | Nat Prod Res | 10.1080/14786419.2014.924931 | 2014 | Anti-Bacterial Agents/chemistry/*isolation & purification/*pharmacology, Ciprofloxacin/pharmacology, Helichrysum/*chemistry, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Moraxella catarrhalis/drug effects, Phenols/analysis/*pharmacology, Pseudomonas aeruginosa/drug effects, *Respiratory System/drug effects/microbiology, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects | Enzymology |
| Pathogenicity | 25712316 | Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms. | Vandevelde NM, Tulkens PM, Muccioli GG, Van Bambeke F | J Antimicrob Chemother | 10.1093/jac/dkv032 | 2015 | Aged, Aged, 80 and over, Albuterol/pharmacology, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Bronchodilator Agents/*pharmacology, Chromatography, High Pressure Liquid, Drug Interactions, Female, Fluoroquinolones/pharmacology, Humans, Ipratropium/pharmacology, Macrolides/pharmacology, Male, Mass Spectrometry, Microbial Viability/*drug effects, Middle Aged, Models, Theoretical, Moxifloxacin, N-Acetylneuraminic Acid/analysis, Pneumococcal Infections/microbiology, Streptococcus pneumoniae/*drug effects/isolation & purification/physiology, Triazoles/pharmacology | Enzymology |
| Metabolism | 25943628 | In vitro expression of Streptococcus pneumoniae ply gene in human monocytes and pneumocytes. | Hu DK, Liu Y, Li XY, Qu Y | Eur J Med Res | 10.1186/s40001-015-0142-4 | 2015 | Alveolar Epithelial Cells/*metabolism, Bacterial Proteins/genetics, Cell Line, *Genes, Bacterial, Humans, In Vitro Techniques, Monocytes/*metabolism, Streptococcus pneumoniae/*genetics/pathogenicity, Streptolysins/*genetics, Virulence/genetics | Pathogenicity |
| Pathogenicity | 26517483 | Ceftaroline activity on certain respiratory tract and wound infection agents at the minimum inhibitory concentration level. | Yanik K, Guluzade E, Bilgin K, Karadag A, Eroglu C, Birinci A, Gunaydin M | J Infect Dev Ctries | 10.3855/jidc.6300 | 2015 | Anti-Bacterial Agents/*pharmacology, Bacterial Infections/microbiology, Cephalosporins/*pharmacology, Haemophilus influenzae/*drug effects/isolation & purification, Humans, Microbial Sensitivity Tests, Moraxella catarrhalis/*drug effects/isolation & purification, Respiratory Tract Infections/*microbiology, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Streptococcus/*drug effects/isolation & purification, Wound Infection/*microbiology | Enzymology |
| Pathogenicity | 27227336 | Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014). | Ceyssens PJ, Van Bambeke F, Mattheus W, Bertrand S, Fux F, Van Bossuyt E, Damee S, Nyssen HJ, De Craeye S, Verhaegen J, Tulkens PM, Vanhoof R | PLoS One | 10.1371/journal.pone.0154816 | 2016 | ATP-Binding Cassette Transporters/*genetics, Amino Acid Substitution, Bacterial Proteins/*genetics, Belgium/epidemiology, DNA Gyrase/*genetics, Drug Resistance, Bacterial/drug effects/*genetics, Female, Fluoroquinolones/*pharmacology, Humans, Longitudinal Studies, Male, *Mutation, Missense, Pneumococcal Infections/drug therapy/epidemiology/genetics, *Streptococcus pneumoniae/genetics/isolation & purification | Enzymology |
| Enzymology | 28107379 | Experimental and In-Silico Investigation of Anti-Microbial Activity of 1-Chloro-2-Isocyanatoethane Derivatives of Thiomorpholine, Piperazine and Morpholine. | Nwuche CO, Ujam OT, Ibezim A, Ujam IB | PLoS One | 10.1371/journal.pone.0170150 | 2017 | Anti-Bacterial Agents/chemistry/pharmacokinetics/*pharmacology, Biological Availability, Computer Simulation, Gram-Negative Bacteria/drug effects, Isocyanates/*chemistry, Microbial Sensitivity Tests, Molecular Docking Simulation, Morpholines/chemistry/*pharmacology, Piperazines/chemistry/*pharmacology | Pathogenicity |
| Pathogenicity | 28567419 | Shin'iseihaito (Xinyiqingfeitang) Suppresses the Biofilm Formation of Streptococcus pneumoniae In Vitro. | Minami M, Konishi T, Takase H, Makino T | Biomed Res Int | 10.1155/2017/4575709 | 2017 | Biofilms/*drug effects, Drugs, Chinese Herbal/*pharmacology, Humans, Medicine, Kampo/*methods, Streptococcus pneumoniae/*physiology | |
| Pathogenicity | 28583022 | Implementation of the new VIRTUO blood culture system: evaluation and comparison to the 3D system using simulated blood cultures. | Miller N, Brassinne L, Allemeersch D | Acta Clin Belg | 10.1080/17843286.2017.1331618 | 2017 | Blood Culture/*instrumentation, Humans, Specimen Handling, Time Factors | |
| Pathogenicity | 28747372 | Determination of Disk Diffusion and MIC Quality Control Ranges for Nafithromycin (WCK 4873), a New Lactone-Ketolide. | Hackel MA, Karlowsky JA, Dressel D, Sahm DF | J Clin Microbiol | 10.1128/JCM.00972-17 | 2017 | Anti-Bacterial Agents/*pharmacology, Disk Diffusion Antimicrobial Tests, Enterococcus faecalis/*drug effects, Haemophilus influenzae/*drug effects, Humans, Ketolides/*pharmacology, Lactones/*pharmacology, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/*drug effects | |
| Pathogenicity | 29341168 | In search of a counter you can count on: relative efficacy of human visual and automated colony counting. | Young LM, Rieman DJ, Walden L, Motz VA | Lett Appl Microbiol | 10.1111/lam.12851 | 2018 | Automation/*methods, Colony Count, Microbial/methods, Escherichia coli/*growth & development, Food Contamination/analysis, Humans, Staphylococcus epidermidis/*growth & development, Streptococcus pneumoniae/*growth & development, Streptococcus pyogenes/*growth & development, Urinary Tract Infections/diagnosis/microbiology, Water Pollution/analysis | |
| Pathogenicity | 30315257 | Synthesis and evaluation of biological activity of benzoxaborole derivatives of azithromycin. | Tevyashova AN, Korolev AM, Mirchink EP, Isakova EB, Osterman IA | J Antibiot (Tokyo) | 10.1038/s41429-018-0107-2 | 2018 | Anti-Bacterial Agents/chemical synthesis/chemistry/*pharmacology, Azithromycin/*analogs & derivatives/chemical synthesis/chemistry/*pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/*drug effects, Microbial Sensitivity Tests, Molecular Structure, Peptide Biosynthesis/drug effects | |
| Metabolism | 30366862 | Gene expression analysis in the potent bactericidal activity of sitafloxacin against Streptococcus pneumoniae. | Kobayashi I, Kanesaka I, Kanayama Katsuse A, Takahashi H, Okumura R, Nakanishi Y, Kaneko A | J Infect Chemother | 10.1016/j.jiac.2018.09.012 | 2018 | Anti-Bacterial Agents/*pharmacology, Bacteriocins/genetics/metabolism, Drug Resistance, Bacterial/genetics, Fluoroquinolones/*pharmacology, Gene Expression Profiling, Gene Expression Regulation, Bacterial/*drug effects, Genes, Bacterial, Microbial Sensitivity Tests, Streptococcus pneumoniae/drug effects/*genetics/metabolism | Pathogenicity |
| 30644702 | CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus. | Kazemian H, Afshar D, Garcia E, Pourmand MR, Jeddi-Tehrani M, Aminharati F, Shokri F, Yazdi MH | Iran J Allergy Asthma Immunol | 2018 | Animals, Antibodies, Bacterial/blood, Bacterial Proteins/genetics/*immunology, Female, Immunity, Humoral, Mice, Mice, Inbred BALB C, Models, Animal, Phagocytosis, Pneumococcal Infections/*prevention & control, Pneumococcal Vaccines/*immunology, Recombinant Proteins/genetics, Serogroup, Streptococcus pneumoniae/*physiology, Vaccination | |||
| Enzymology | 30784307 | Chemical constituents from leaves and trunk bark of Rinorea oblongifolia (Violaceae). | Munvera AM, Ouahouo BMW, Mkounga P, Mbekou MIK, Nuzhat S, Choudhary MI, Nkengfack AE | Nat Prod Res | 10.1080/14786419.2019.1573230 | 2019 | Anti-Bacterial Agents/chemistry/*isolation & purification, Bacteria/drug effects, Haemophilus influenzae/drug effects, Microbial Sensitivity Tests, Plant Bark/*chemistry, Plant Extracts/chemistry, Plant Leaves/*chemistry, Triterpenes/analysis/isolation & purification, Violaceae/*chemistry | Phylogeny |
| Genetics | 30834385 | Complete Genome Sequences of Streptococcus pneumoniae Strains HU-OH (Serotype 3, Sequence Type 183 [ST183]), NU83127 (Serotype 4, ST246), and ATCC 49619 (Serotype 19F, ST1203). | Nagaoka K, Konno S, Murase K, Kikuchi T, Morinaga Y, Yanagihara K, Nakagawa I | Microbiol Resour Announc | 10.1128/MRA.01504-18 | 2019 | ||
| Metabolism | 31231868 | Impact of different Streptococcus pneumoniae on the secretion of interleukin and adhesin from THP-1 monocytes. | Ren P, Zhang J, Yu L, Qu Y, Jiang X, Zhou Y, Hu D, Gao C | J Clin Lab Anal | 10.1002/jcla.22927 | 2019 | Humans, Intercellular Adhesion Molecule-1/*metabolism, Interleukins/*metabolism, Monocytes/*metabolism, Solubility, Streptococcus pneumoniae/*physiology, THP-1 Cells | Pathogenicity |
| Cultivation | 31315953 | Determination of MIC Quality Control Ranges for the Novel Gyrase Inhibitor Zoliflodacin. | Miller AA, Traczewski MM, Huband MD, Bradford PA, Mueller JP | J Clin Microbiol | 10.1128/JCM.00567-19 | 2019 | Anti-Bacterial Agents/*pharmacology, Barbiturates/*pharmacology, Culture Media, Enzyme Inhibitors/*pharmacology, Gram-Negative Bacteria/*drug effects, Gram-Positive Bacteria/*drug effects, Isoxazoles, Microbial Sensitivity Tests/*methods/*standards, Morpholines, Oxazolidinones, Quality Control, Spiro Compounds/*pharmacology | Pathogenicity |
| 31641579 | Standardisation and evaluation of a quantitative multiplex real-time PCR assay for the rapid identification of Streptococcus pneumoniae. | Ganaie FA, Govindan V, Ravi Kumar KL | Pneumonia (Nathan) | 10.15172/pneu.2015.6/559 | 2015 | |||
| 32864363 | Autolysin (lytA) recombinant protein: a potential target for developing vaccines against pneumococcal infections. | Afshar D, Rafiee F, Kheirandish M, Ohadian Moghadam S, Azarsa M | Clin Exp Vaccine Res | 10.7774/cevr.2020.9.2.76 | 2020 | |||
| 32952512 | Antibacterial Activity of Ritchiea albersii Gilg and Cynoglossum amplifolium Leaves Extracts against Selected Bacteria. | Engiso H, Worku T, Nureye D, Salahaddin M, Woldeselassie W, Hambisa S, Sharief N | Saudi J Med Med Sci | 10.4103/sjmms.sjmms_276_19 | 2020 | |||
| 32994906 | Psp140: an immunodominant antigen in the supernatant of Streptococcus pneumoniae culture. | Afshar D, Moghadam SO, Dehkordi FS, Ranjbar R, Hasanzadeh A | Iran J Microbiol | 10.18502/ijm.v12i4.3938 | 2020 | |||
| 33134136 | Antibacterial oral sprays from kaffir lime (Citrus hystrix DC.) fruit peel oil and leaf oil and their activities against respiratory tract pathogens. | Srifuengfung S, Bunyapraphatsara N, Satitpatipan V, Tribuddharat C, Junyaprasert VB, Tungrugsasut W, Srisukh V | J Tradit Complement Med | 10.1016/j.jtcme.2019.09.003 | 2019 | |||
| Phylogeny | 33352708 | A New Phage Lysin Isolated from the Oral Microbiome Targeting Streptococcus pneumoniae. | van der Kamp I, Draper LA, Smith MK, Buttimer C, Ross RP, Hill C | Pharmaceuticals (Basel) | 10.3390/ph13120478 | 2020 | ||
| Pathogenicity | 33734645 | In-laboratory quality control of nutrients for automatic bacteriology analyzer YUNON(R)Labstar 50. | Boronina LG, Samatova EV, Kukushkina MP, Panova SA, Ustyugova SS | Klin Lab Diagn | 10.51620/0869-2084-2021-66-2-110-114 | 2021 | Anti-Bacterial Agents, *Bacterial Infections, *Bacteriology, Child, Humans, Laboratories, Microbial Sensitivity Tests, Nutrients, Quality Control | |
| Pathogenicity | 35099454 | Equal adhesion to pneumocytes by pneumococci inducing bacteraemia and pneumonia. | Qu Y, Li M, Gao C, Zhang J, Luo X, Wang G, Jiang X, Yang J, Li X, Hu D, Zhu W, Shen W | J Pak Med Assoc | 10.47391/JPMA.11-784 | 2022 | Alveolar Epithelial Cells, Antigens, Bacterial, *Bacteremia, Humans, *Pneumonia, Streptococcus pneumoniae | |
| Pathogenicity | 35115773 | Nanobubble Ozone Stored in Hyaluronic Acid Decorated Liposomes: Antibacterial, Anti-SARS-CoV-2 Effect and Biocompatibility Tests. | Sabanci AU, Erkan Alkan P, Mujde C, Polat HU, Ornek Erguzeloglu C, Bisgin A, Ozakin C, Temel SG | Int J Nanomedicine | 10.2147/IJN.S328090 | 2022 | Animals, Anti-Bacterial Agents/pharmacology, *COVID-19, Chlorocebus aethiops, Cricetinae, Female, Humans, Hyaluronic Acid, Liposomes, Male, Mice, *Ozone, Rabbits, SARS-CoV-2, Vero Cells | |
| 35210807 | Probiotic Combination CBLEB Alleviates Streptococcus pneumoniae Infection Through Immune Regulation in Immunocompromised Rats. | Lv L, Peng L, Shi D, Shao L, Jiang H, Yan R | J Inflamm Res | 10.2147/JIR.S348047 | 2022 | |||
| Cultivation | 35447278 | Preservation of Streptococcus pneumoniae quality control strains using chocolate agar blocks in glycerol at minus 70 degrees celsius. | Chandrasingh S, Subramaniam M, Nair S | J Microbiol Methods | 10.1016/j.mimet.2022.106469 | 2022 | Agar, *Chocolate, Culture Media, Glycerol/pharmacology, Quality Control, *Streptococcus pneumoniae | |
| Pathogenicity | 35846995 | Assessment of the Anti-Inflammatory, Antibacterial and Anti-Aging Properties and Possible Use on the Skin of Hydrogels Containing Epilobium angustifolium L. Extracts. | Nowak A, Zagorska-Dziok M, Peruzynska M, Cybulska K, Kucharska E, Ossowicz-Rupniewska P, Piotrowska K, Duchnik W, Kucharski L, Sulikowski T, Drozdzik M, Klimowicz A | Front Pharmacol | 10.3389/fphar.2022.896706 | 2022 | ||
| 35890128 | Phenolic Secondary Metabolites and Antiradical and Antibacterial Activities of Different Extracts of Usnea barbata (L.) Weber ex F.H.Wigg from Calimani Mountains, Romania. | Popovici V, Bucur L, Gird CE, Popescu A, Matei E, Cozaru GC, Schroder V, Ozon EA, Fita AC, Lupuliasa D, Aschie M, Caraiane A, Botnarciuc M, Badea V | Pharmaceuticals (Basel) | 10.3390/ph15070829 | 2022 |
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| 20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
| 41690 | Curators of the CIP | https://brclims.pasteur.fr/brcWeb/souche/detail/1/16238 | ||||
| 51650 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 33638) | https://www.ccug.se/strain?id=33638 | |||
| 66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 68380 | Automatically annotated from API rID32A | |||||
| 68381 | Automatically annotated from API rID32STR | |||||
| 68382 | Automatically annotated from API zym | |||||
| 69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
| 69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
| 69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |||
| 83867 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID7827.1 | StrainInfo: A central database for resolving microbial strain identifiers | |||
| 121897 | Curators of the CIP | Collection of Institut Pasteur (CIP 104340) | https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20104340 |