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Strain identifier

BacDive ID: 14472

Type strain: No

Species: Staphylococcus aureus

Strain history: <- CCUG; CCUG 9128 <- NCTC; NCTC 10625 <- ATCC; ATCC 13565

NCBI tax ID(s): 1280 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 7600

BacDive-ID: 14472

DSM-Number: 18597

keywords: genome sequence, Bacteria, aerobe, mesophilic, human pathogen

description: Staphylococcus aureus DSM 18597 is an aerobe, mesophilic human pathogen that was isolated from ham.

NCBI tax id

  • NCBI tax id: 1280
  • Matching level: species

strain history: <- CCUG; CCUG 9128 <- NCTC; NCTC 10625 <- ATCC; ATCC 13565

doi: 10.13145/bacdive14472.20221219.7.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Bacilli
  • order: Caryophanales
  • family: Staphylococcaceae
  • genus: Staphylococcus
  • species: Staphylococcus aureus
  • full scientific name: Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)
  • synonyms

    • @ref: 20215
    • synonym: Staphylococcus aureus subsp. anaerobius

@ref: 7600

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Bacillales

family: Staphylococcaceae

genus: Staphylococcus

species: Staphylococcus aureus

full scientific name: Staphylococcus aureus Rosenbach 1884

type strain: no

Morphology

cell morphology

  • @ref: 69480
  • gram stain: positive
  • confidence: 94

colony morphology

  • @ref: 7600
  • type of hemolysis: gamma
  • incubation period: 1-2 days

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
7600COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
7600TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://mediadive.dsmz.de/medium/92Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water

culture temp

@refgrowthtypetemperaturerange
7600positivegrowth37mesophilic
45168positivegrowth37mesophilic

Physiology and metabolism

oxygen tolerance

  • @ref: 45168
  • oxygen tolerance: aerobe

antibiogram

@refmediumincubation temperatureincubation timeoxygen conditionPenicillin Goxacillinampicillinticarcillinmezlocillincefalotincefazolincefotaximeaztreonamimipenemtetracyclinechloramphenicolgentamycinamikacinvancomycinerythromycinlincomycinofloxacinnorfloxacincolistinpipemidic acidnitrofurantoinbacitracinpolymyxin bkanamycinneomycindoxycyclineceftriaxoneclindamycinfosfomycinmoxifloxacinlinezolidnystatinquinupristin/dalfopristinteicoplaninpiperacillin/tazobactam
7600Mueller-Hinton Agar371aerob20302024-262034303004632302222203030282601222206222032-34263432323402816-1826
7600Mueller-Hinton Agar3718-2028202418-20343028042-4430-323022-242218-2030-322828-302801220-22166-8222032-34n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.

spore formation

  • @ref: 69480
  • spore formation: no
  • confidence: 89.447

halophily

  • @ref: 69480
  • halophily level: halophilic
  • confidence: 96.431

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6837522599arabinose-fermentation
6837532528turanose+fermentation
6837559640N-acetylglucosamine+fermentation
6837517992sucrose+fermentation
6837517632nitrate+reduction
6837517057cellobiose-fermentation
6837516988D-ribose-fermentation
6837516634raffinose-fermentation
6837516899D-mannitol+fermentation
6837527082trehalose+fermentation
6837517716lactose+fermentation
6837517306maltose+fermentation
6837516024D-mannose+fermentation
6837515824D-fructose+fermentation
6837517634D-glucose+fermentation
683754853esculin-hydrolysis
6837518257ornithine-degradation
6837529016arginine+hydrolysis
6837516199urea+hydrolysis

antibiotic resistance

  • @ref: 68375
  • ChEBI: 28368
  • metabolite: novobiocin
  • is antibiotic: yes
  • is sensitive: yes
  • sensitivity conc.: 1.8 µg

enzymes

@refvalueactivityec
7600catalase+1.11.1.6
7600cytochrome-c oxidase-1.9.3.1
68375beta-glucuronidase-3.2.1.31
68375alkaline phosphatase+3.1.3.1
68375L-arginine arylamidase-
68375beta-galactosidase-3.2.1.23
68375beta-glucosidase-3.2.1.21
68375ornithine decarboxylase-4.1.1.17
68375arginine dihydrolase+3.5.3.6
68375urease+3.5.1.5

fatty acid profile

  • fatty acids

    @reffatty acidpercentageECL
    45168C16:02.716
    45168C17:00.517
    45168C18:04.418
    45168C20:00.720
    45168C14:0 ISO1.513.618
    45168C15:0 ANTEISO46.614.711
    45168C15:0 ISO11.514.621
    45168C16:0 iso315.626
    45168C17:0 anteiso16.316.722
    45168C17:0 iso6.616.629
    45168C18:0 ISO0.817.632
    45168C18:1 ω9c0.717.769
    45168C18:2 ω6,9c/C18:0 ANTE2.617.724
    45168C19:0 ANTEISO1.418.729
    45168C19:0 ISO0.918.633
  • type of FA analysis: whole cell analysis
  • method/protocol: CCUG

API ID32STA

@refUREADH ArgODCESCGLUFRUMNEMALLACTREMANRAFRIBCELNITVPbeta GALArgAPALPyrANOVOSACNAGTURARAbeta GUR
7600++--+++++++---++--++-+++--
7600++--+++++++---++--+--+++--
7600++--+++++++---++--++-+++--
7600++--+++++++---++--++-+++--
45168++--+++++++---+---+--+++--

Isolation, sampling and environmental information

isolation

@refsample type
7600ham
45168Ham

isolation source categories

  • Cat1: #Engineered
  • Cat2: #Food production
  • Cat3: #Meat

Safety information

risk assessment

  • @ref: 7600
  • pathogenicity human: yes
  • pathogenicity animal: yes
  • biosafety level: 2
  • biosafety level comment: Risk group (German classification)

Sequence information

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Staphylococcus aureus NCTC10652GCA_900458095contigncbi1280
66792Staphylococcus aureus strain NCTC106521280.18095wgspatric1280

External links

@ref: 7600

culture collection no.: DSM 18597, ATCC 13565, CCUG 9128, NCTC 10625, CECT 976, NCTC 10652, FDA 196E

straininfo link

@refpassport
20218http://www.straininfo.net/strains/97015
20218http://www.straininfo.net/strains/144216
20218http://www.straininfo.net/strains/341832

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Enzymology4022103Bacteria and food poisoning organisms in milk.Abo-Elnaga IG, Hessain A, Sarhan HRNahrung10.1002/food.198502904191985Animals, Cattle, Enterotoxins/*analysis, Female, Foodborne Diseases/*microbiology, Goats, Milk/*microbiology, Salmonella/isolation & purification, Salmonella Food Poisoning/microbiology, Sheep, Staphylococcus aureus/isolation & purification/metabolism, Time FactorsPhylogeny
Cultivation8069779Effect of ionizing dose rate on the radioresistance of some food pathogenic bacteria.Dion P, Charbonneau R, Thibault CCan J Microbiol10.1139/m94-0601994Animals, Bacteria/growth & development/*radiation effects, Chickens, Culture Media, Dose-Response Relationship, Radiation, Food Contamination/prevention & control, *Food Irradiation, *Food Microbiology, Hypotonic Solutions, Meat, *Radiation Dosage, *Radiation Tolerance, Sodium Chloride, Species Specificity, Tissue ExtractsBiotechnology
Biotechnology9709206The combined effect of high hydrostatic pressure and mild heat on inactivation of pathogens in milk and poultry.Patterson MF, Kilpatrick DJJ Food Prot10.4315/0362-028x-61.4.4321998Animals, Disinfection/*methods, Escherichia coli O157/growth & development, Food Microbiology, *Hot Temperature, *Hydrostatic Pressure, Milk/*microbiology, Poultry Products/*microbiology, Staphylococcus aureus/growth & development, Time FactorsStress
Biotechnology12635735Survival of Staphylococcus aureus ATCC 13565 in intermediate moisture foods is highly variable.Vora P, Senecal A, Schaffner DWRisk Anal10.1111/1539-6924.003022003Animals, Bread/microbiology, Cattle, Colony Count, Microbial, Computer Simulation, Food Analysis, *Food Microbiology, Humans, Meat/microbiology, Models, Biological, Poultry Products/microbiology, Risk Assessment, Staphylococcus aureus/growth & development/*isolation & purification, Water/analysisPathogenicity
Pathogenicity15186441Effect of combined physico-chemical preservatives on enterocin AS-48 activity against the enterotoxigenic Staphylococcus aureus CECT 976 strain.Ananou S, Valdivia E, Martinez Bueno M, Galvez A, Maqueda MJ Appl Microbiol10.1111/j.1365-2672.2004.02276.x2004Anti-Bacterial Agents/*pharmacology, Bacteriocins/*pharmacology, Bacteriological Techniques, Enterotoxins/metabolism, Food Preservatives/*pharmacology, Hot Temperature, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Sodium Chloride/pharmacology, Staphylococcus aureus/*drug effects/growth & developmentStress
Pathogenicity15969054[Gene cloning, soluble expression and activity analysis of rSEA].Xu QB, Liu CX, Ma QJSheng Wu Gong Cheng Xue Bao2003Cell Line, Tumor, Cell Proliferation/drug effects, Cells, Cultured, Cloning, Molecular, Electrophoresis, Polyacrylamide Gel, Enterotoxins/*genetics/*metabolism/pharmacology, Humans, Leukocytes, Mononuclear/cytology/drug effects, Plasmids, Polymerase Chain Reaction, SolubilityEnzymology
Pathogenicity16245711Stability of enterocin AS-48 in fruit and vegetable juices.Grande MJ, Lucas R, Valdivia E, Abriouel H, Maqueda M, Omar NB, Martinez-Canamero M, Galvezi AJ Food Prot10.4315/0362-028x-68.10.20852005Bacillus cereus/drug effects/growth & development, Bacteriocins/*pharmacology, Beverages/*microbiology, Colony Count, Microbial, Food Preservation/*methods, Food Preservatives/*pharmacology, *Fruit, Listeria monocytogenes/drug effects/growth & development, Staphylococcus aureus/drug effects/growth & development, Temperature, Time Factors, *Vegetables
Pathogenicity17106084Fate of Staphylococcus aureus in cheese treated by ultrahigh pressure homogenization and high hydrostatic pressure.Lopez-Pedemonte T, Brinez WJ, Roig-Sagues AX, Guamis BJ Dairy Sci10.3168/jds.S0022-0302(06)72502-42006Animals, Cheese/analysis/*microbiology, Colony Count, Microbial, Dairying/*methods, Enterotoxins/analysis, Food Handling/*methods, Hydrostatic Pressure, Milk/microbiology, Pressure, Staphylococcus aureus/isolation & purification/*physiology, Temperature, Time FactorsEnzymology
Pathogenicity17412428Identification of Staphylococcus aureus strains negative for enterotoxins A, B and C isolated from bovine mastitis in Mexico.Gomez C, Pinal L, Franco J, Carrillo JM, Ramirez JVet Immunol Immunopathol10.1016/j.vetimm.2007.02.0112007Animals, Cattle, Enterotoxins/analysis/*genetics, Female, Mastitis, Bovine/microbiology/pathology, Mexico, Polymerase Chain Reaction, Staphylococcal Infections/microbiology/pathology/*veterinary, Staphylococcus aureus/genetics/*isolation & purification/pathogenicityEnzymology
Enzymology17418309Adhesion and detachment kinetics of several strains of Staphylococcus aureus subsp. aureus under three different experimental conditions.Herrera JJ, Cabo ML, Gonzalez A, Pazos I, Pastoriza LFood Microbiol10.1016/j.fm.2007.01.0012007Bacterial Adhesion/*physiology, Biofilms/*growth & development, *Consumer Product Safety, Culture Media/chemistry, Food Contamination/analysis/*prevention & control, Food Handling/*methods, Food Microbiology, Humans, Kinetics, Polypropylenes, Staphylococcal Food Poisoning/microbiology/prevention & control, Staphylococcus aureus/growth & development/pathogenicity/*physiology, Time FactorsBiotechnology
Pathogenicity17594455Bactericidal synergism through enterocin AS-48 and chemical preservatives against Staphylococcus aureus.Ananou S, Maqueda M, Martinez-Bueno M, Galvez A, Valdivia ELett Appl Microbiol10.1111/j.1472-765X.2007.02155.x2007Anti-Bacterial Agents/*pharmacology, Bacteriocins/*pharmacology, Benzoates/pharmacology, Carboxylic Acids/*pharmacology, Colony Count, Microbial, Drug Synergism, Enterotoxins/metabolism, Food Preservatives/chemistry/*pharmacology, Humans, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Polyphosphates/*pharmacology, Sorbic Acid/pharmacology, Staphylococcus aureus/*drug effects/growth & development/metabolismMetabolism
Metabolism20951456A proteomic approach to cold acclimation of Staphylococcus aureus CECT 976 grown at room and human body temperatures.Sanchez B, Cabo ML, Margolles A, Herrera JJInt J Food Microbiol10.1016/j.ijfoodmicro.2010.09.0152010Acclimatization/*physiology, Bacterial Proteins/metabolism, Body Temperature/*physiology, *Cold Temperature, Gene Expression Regulation, Bacterial, Humans, *Proteomics, Staphylococcus aureus/*growth & development/*metabolism, TemperaturePathogenicity
Pathogenicity24375170In-vitro anticancer and antimicrobial activities of PLGA/silver nanofiber composites prepared by electrospinning.Almajhdi FN, Fouad H, Khalil KA, Awad HM, Mohamed SH, Elsarnagawy T, Albarrag AM, Al-Jassir FF, Abdo HSJ Mater Sci Mater Med10.1007/s10856-013-5131-y2013Anti-Infective Agents/*administration & dosage, Antineoplastic Agents/*administration & dosage, Biocompatible Materials/*chemistry, Cell Line, *Drug Delivery Systems, Electrochemical Techniques, Hep G2 Cells, Humans, Lactic Acid/chemistry, Liver Neoplasms/drug therapy, Materials Testing, Metal Nanoparticles/chemistry/ultrastructure, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Nanocomposites/chemistry/ultrastructure, Nanofibers/chemistry/ultrastructure, Polyglycolic Acid/chemistry, Polylactic Acid-Polyglycolic Acid Copolymer, Silver/*administration & dosage
26760947Effect of NaCl on Biofilm Formation of the Isolate from Staphylococcus aureus Outbreak Linked to Ham.Lee S, Choi KH, Yoon YKorean J Food Sci Anim Resour10.5851/kosfa.2014.34.2.2572014
Pathogenicity29446687icaA Gene of Staphylococcus aureus Responds to NaCl, Leading to Increased Biofilm Formation.Lee S, Kim S, Lee H, Ha J, Lee J, Choi Y, Oh H, Yoon Y, Choi KHJ Food Prot10.4315/0362-028X.JFP-17-2382018*Biofilms, Genes, Bacterial, Sodium Chloride/*pharmacology, Staphylococcus aureus/*drug effects/genetics/physiology
Metabolism30431711In vitro characteristics of an airway barrier-disrupting factor secreted by Staphylococcus aureus.Murphy J, Ramezanpour M, Drilling A, Roscioli E, Psaltis AJ, Wormald PJ, Vreugde SInt Forum Allergy Rhinol10.1002/alr.222322018Cells, Cultured, Chronic Disease, Culture Media, Conditioned/*analysis/metabolism, Electric Impedance, Enterotoxins/metabolism, Hemolysin Proteins/metabolism, Humans, Lipopolysaccharides/metabolism, Nasal Mucosa/*metabolism/pathology, Permeability, Rhinitis/*microbiology/physiopathology, Sinusitis/*microbiology/physiopathology, Staphylococcal Infections/*microbiology/physiopathology, Staphylococcus aureus/*physiology, Teichoic Acids/metabolism, Tight Junctions/*metabolismPathogenicity
Biotechnology30526054Effects of Temperature Abuse on the Growth and Staphylococcal Enterotoxin A Gene (sea) Expression of Staphylococcus aureus in Milk.Babic M, Pajic M, Radinovic M, Bobos S, Bulajic S, Nikolic A, Velebit BFoodborne Pathog Dis10.1089/fpd.2018.25442018Animals, Cattle, Dairying, Enterotoxins/*metabolism, Female, Food Contamination/analysis, *Food Microbiology, Milk/*microbiology, Pasteurization, Serbia, Staphylococcal Food Poisoning/*microbiology, Staphylococcus aureus/*genetics, TemperaturePathogenicity
Pathogenicity30711830Repurposing ibuprofen to control Staphylococcus aureus biofilms.Oliveira IM, Borges A, Borges F, Simoes MEur J Med Chem10.1016/j.ejmech.2019.01.0462019Biofilms/*drug effects/*growth & development, Cell Membrane/drug effects/metabolism, *Drug Repositioning, Ibuprofen/*pharmacology, Microbial Sensitivity Tests, Staphylococcus aureus/cytology/*drug effects/*physiology, Time FactorsMetabolism
31304466Mathematical Models to Describe the Kinetic Behavior of Staphylococcus aureus in Jerky.Ha J, Lee J, Lee S, Kim S, Choi Y, Oh H, Kim Y, Lee Y, Seo Y, Yoon YFood Sci Anim Resour10.5851/kosfa.2019.e282019
Phylogeny31692847Isolation and screening of actinomycetes producing antimicrobial substances from an extreme Moroccan biotope.El Karkouri A, Assou SA, El Hassouni MPan Afr Med J10.11604/pamj.2019.33.329.190182019Actinobacteria/isolation & purification/*metabolism, Anti-Infective Agents/isolation & purification/*pharmacology, Bacteria/*drug effects, Candida albicans/drug effects, Culture Media, Microbial Sensitivity Tests, Morocco, *Soil Microbiology, TemperatureEnzymology
33163506Rheological Behavior, Antimicrobial and Quorum Sensig Inhibition Study of an Argentinean Oregano Essential Oil Nanoemulsion.Asensio CM, Quiroga PR, Al-Gburi A, Huang Q, Grosso NRFront Nutr10.3389/fnut.2020.5699132020
Pathogenicity34279398Chemical Composition, Antioxidant, Antimicrobial and Cytotoxic/Cytoprotective Activity of Non-Polar Extracts of Grape (Vitis labrusca cv. Bordeaux) and Blackberry (Rubus fruticosus) Seeds.Junior TK, de Moura C, do Carmo MAV, Azevedo L, Esmerino LA, Tardivo RC, Kilpelainen P, Granato DMolecules10.3390/molecules261340572021Anti-Infective Agents/*chemistry/pharmacology/toxicity, Antioxidants/*chemistry/pharmacology/toxicity, Escherichia coli/drug effects, Fatty Acids/analysis, Flavonoids/analysis, Grape Seed Extract/*chemistry/pharmacology, Rubus/*chemistry, Staphylococcus aureus/drug effects
Pathogenicity34774677Purple tea (Camellia sinensis var. assamica) leaves as a potential functional ingredient: From extraction of phenolic compounds to cell-based antioxidant/biological activities.de Moura C, Kabbas Junior T, Pedreira FRO, Azevedo L, Furtado MM, Sant'Ana AS, Franchin M, Gonzaga VR, Cui Y, Wen M, Zhang L, Pereira RP, Granato DFood Chem Toxicol10.1016/j.fct.2021.1126682021A549 Cells, Anti-Bacterial Agents/chemistry/pharmacology, Anti-Inflammatory Agents/chemistry/pharmacology, *Antioxidants/chemistry/pharmacology, Bacteria/drug effects, Camellia sinensis/*chemistry, Cell Line, Tumor, Cell Proliferation/drug effects, Cytokines/metabolism, Humans, Phenols/chemistry/pharmacology, *Plant Extracts/chemistry/pharmacology, Plant Leaves/chemistry, Reactive Oxygen Species/metabolismMetabolism
Pathogenicity35011396Antibacterial Activity of Clay Soils against Food-Borne Salmonella typhimurium and Staphylococcus aureus.Azmi NN, Mahyudin NA, Wan Omar WH, Mahmud Ab Rashid NK, Ishak CF, Abdullah AH, Sharples GJMolecules10.3390/molecules270101702021Anti-Bacterial Agents/*chemistry/*pharmacology, Cations/chemistry, Clay/*chemistry, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Particle Size, Salmonella typhimurium/*drug effects, Soil/*chemistry, Staphylococcus aureus/*drug effects
35625264Screening of Natural Molecules as Adjuvants to Topical Antibiotics to Treat Staphylococcus aureus from Diabetic Foot Ulcer Infections.Oliveira D, Borges A, Saavedra MJ, Borges F, Simoes MAntibiotics (Basel)10.3390/antibiotics110506202022

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
7600Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 18597)https://www.dsmz.de/collection/catalogue/details/culture/DSM-18597
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
45168Curators of the CCUGCulture Collection University of Gothenburg (CCUG) (CCUG 9128)https://www.ccug.se/strain?id=9128
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
68375Automatically annotated from API ID32STA
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)