Archive BacDiveID:10.13145/bacdive14449.20230509.8.1

Strain identifier

BacDive ID: 14449

Type strain:

Species: Staphylococcus aureus

Strain Designation: Wichita

Strain history: CIP <- 1990, ATCC <- Micro-media Syst. Inc. <- E.H. Gerlach: strain Wichita

NCBI tax ID(s): 1280 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.

General

@ref: 1123

BacDive-ID: 14449

DSM-Number: 2569

keywords: genome sequence, 16S sequence, Bacteria, facultative anaerobe, spore-forming, mesophilic, human pathogen

description: Staphylococcus aureus Wichita is a facultative anaerobe, spore-forming, mesophilic human pathogen that was isolated from wound.

NCBI tax id

NCBI tax id: 1280
Matching level: species

strain history

@ref	history
1123	<- ATCC; ATCC 29213 <- Micro-media Systems Inc.; <- E.H. Gerlach; Wichita
67770	R. Sakazaki 85047 <-- ATCC 29213 <-- Micro-Media Systems, Inc. <-- E. H. Gerlach strain Wichita.
116609	CIP <- 1990, ATCC <- Micro-media Syst. Inc. <- E.H. Gerlach: strain Wichita

doi: 10.13145/bacdive14449.20230509.8.1

Name and taxonomic classification

LPSN

@ref: 20215
description: domain/bacteria
keyword: phylum/bacillota
domain: Bacteria
phylum: Bacillota
class: Bacilli
order: Caryophanales
family: Staphylococcaceae
genus: Staphylococcus
species: Staphylococcus aureus
full scientific name: Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)
synonyms
- @ref: 20215
- synonym: Staphylococcus aureus subsp. anaerobius

@ref: 1123

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Bacillales

family: Staphylococcaceae

genus: Staphylococcus

species: Staphylococcus aureus

full scientific name: Staphylococcus aureus Rosenbach 1884

strain designation: Wichita

type strain: no

Morphology

cell morphology

@ref	motility	confidence	gram stain	cell shape
69480	no	94.688
69480		100	positive
116609	no		positive	coccus-shaped

colony morphology

@ref	type of hemolysis	hemolysis ability	incubation period
1123	beta	1	1-2 days
116609		1

Culture and growth conditions

culture medium

@ref	name	growth	link	composition
1123	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)	yes	https://mediadive.dsmz.de/medium/693	Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
1123	TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)	yes	https://mediadive.dsmz.de/medium/92	Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
36626	MEDIUM 72- for trypto casein soja agar	yes		Distilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
116609	CIP Medium 72	yes	https://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72

culture temp

@ref	growth	type	temperature	range
1123	positive	growth	37	mesophilic
36626	positive	growth	30	mesophilic
67770	positive	growth	37	mesophilic
116609	positive	growth	10-37
116609	no	growth	45	thermophilic

Physiology and metabolism

oxygen tolerance

@ref: 116609
oxygen tolerance: facultative anaerobe

antibiogram

@ref	medium	incubation temperature	oxygen condition	Penicillin G	oxacillin	ampicillin	ticarcillin	mezlocillin	cefalotin	cefazolin	cefotaxime	imipenem	tetracycline	chloramphenicol	gentamycin	amikacin	vancomycin	erythromycin	lincomycin	ofloxacin	norfloxacin	colistin	pipemidic acid	nitrofurantoin	bacitracin	polymyxin b	kanamycin	neomycin	doxycycline	ceftriaxone	clindamycin	fosfomycin	moxifloxacin	linezolid	nystatin	quinupristin/dalfopristin	teicoplanin	piperacillin/tazobactam	incubation time
1123	Mueller-Hinton Agar	37	aerob	24	32	24	26-28	22	38	32	26-28	48	30	24-26	24	22	18	28	28-30	26-28	22-24	6	8	22	14	6	22-24	22	32	26	32	28-30	28-30	32	0	26	16	26-28
1123	Mueller-Hinton Agar	37	aerob	24	30-32	24	28-30	22-24	38	34	30	48	30	26	22-24	24	18	30	30	26-28	24-26	0	10	22	18	10	24-26	20	28-30	28-30	34-36	36	30	32	0	26	16	28-30	1
1123	Mueller-Hinton Agar	37	aerob	22	32	24	28	22	36-38	32	32	48	30	26-28	24	24	18	28-30	30	28	28	0	10-12	22	16	8	24	20	30	30	32	46	32	30	0	26	16	28-30	1
1123	Mueller-Hinton Agar	37	aerob	24	32	26	28	24	38	34	30-32	50	32-34	28-30	26	26	20	30	30	28-30	30	0	10	22	18-20	10	26-28	24	34	30	36-38	48-50	34	34	0	28	18	30
1123	Mueller-Hinton Agar			24	32	24	30	22	38	34	32	50	32	30	24	24	18	30	30	26-28	26	0	10	22	18	8	24	22	32	30	34	44	32	30	0	26-28	16	30
1123	Mueller-Hinton Agar			22	32	22-24	26-28	22	38	34	30	46-48	28-30	26-28	24	24	20	28	28	28	28	0	10	20-22	16	8	32	20-22	30-32	30	32	30	32-34	28-30	0	26	16	28
1123	Mueller-Hinton Agar			24	34	24	28	22	38	34	30	48-50	30	28-30	22-24	24	20	28	28	28	26-28	0	10	22	16	6-8	34	22	30-32	30	34	32-34	34	30	0	28	16	28
1123	Mueller-Hinton Agar	37		10	24	12	16	12	28	22	22	36	18	16	16	14	12	16	18	18	18	0	8	14	12	6	16	14	18	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.
1123	Mueller-Hinton Agar	37		12	26	16	20	14	30-32	24-26	22	34	20	18	18	16	14-16	18	18	12-14	14-16	0	6	16	10	0	16	14-16	22	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.
1123	Mueller-Hinton Agar	37	aerob	22	32-34	22	28	22	38	34	30	48	30-32	28	24	24	20	28	28	28	30	0	10	20	14	8	24	22-24	30	30	32-34	32	32	32	0	26	18	28-30
1123	Mueller-Hinton Agar	37	aerob	22	32-34	22	28	22	38	34	30	48	30-32	28	24	24	20	28	28	28	30	0	10	20	14	8	24	22-24	30	30	32-34	32	32	32	0	26	18	28-30

spore formation

@ref	spore formation	confidence
69481	yes	100
69480	yes	99.999

observation

@ref: 1123
observation: MRSA

metabolite utilization

@ref	Chebi-ID	metabolite	utilization activity	kind of utilization tested
116609	606565	hippurate	+	hydrolysis
116609	17632	nitrate	+	reduction
116609	16301	nitrite	-	reduction
68375	29016	arginine	+	hydrolysis
68375	18257	ornithine	-	degradation
68375	4853	esculin	-	hydrolysis
68375	17634	D-glucose	+	fermentation
68375	15824	D-fructose	+	fermentation
68375	16024	D-mannose	+	fermentation
68375	17306	maltose	+	fermentation
68375	17716	lactose	+	fermentation
68375	16899	D-mannitol	+	fermentation
68375	16634	raffinose	-	fermentation
68375	16988	D-ribose	-	fermentation
68375	17057	cellobiose	-	fermentation
68375	17992	sucrose	+	fermentation
68375	59640	N-acetylglucosamine	+	fermentation
68375	22599	arabinose	-	fermentation

antibiotic resistance

@ref: 116609
metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
is antibiotic: yes
is sensitive: no
is resistant: yes

metabolite production

@ref	Chebi-ID	metabolite	production
68375	15688	acetoin	yes
116609	35581	indole	no

metabolite tests

@ref: 68375
Chebi-ID: 15688
metabolite: acetoin
voges-proskauer-test: +

enzymes

@ref	value	activity	ec
1123	catalase	+	1.11.1.6
1123	cytochrome-c oxidase	-	1.9.3.1
68375	beta-glucuronidase	-	3.2.1.31
68375	alkaline phosphatase	+	3.1.3.1
68375	L-arginine arylamidase	-
68375	beta-glucosidase	-	3.2.1.21
68375	ornithine decarboxylase	-	4.1.1.17
68375	arginine dihydrolase	+	3.5.3.6
116609	oxidase	-
116609	beta-galactosidase	+	3.2.1.23
116609	alcohol dehydrogenase	+	1.1.1.1
116609	gelatinase	-
116609	amylase	-
116609	DNase	+
116609	caseinase	-	3.4.21.50
116609	catalase	+	1.11.1.6
116609	coagulase	+
116609	tween esterase	-
116609	gamma-glutamyltransferase	-	2.3.2.2
116609	lecithinase	+
116609	lipase	+
116609	lysine decarboxylase	-	4.1.1.18
116609	ornithine decarboxylase	-	4.1.1.17
116609	urease	+	3.5.1.5

fatty acid profile

fatty acids

@ref	fatty acid	percentage	ECL
46381	C16:0	1.7	16
46381	C18:0	2.4	18
46381	C14:0 ISO	0.6	13.618
46381	C15:0 ANTEISO	55.1	14.711
46381	C15:0 ISO	7.9	14.621
46381	C16:0 iso	1.4	15.626
46381	C17:0 anteiso	17.4	16.722
46381	C17:0 iso	4.1	16.629
46381	C18:1 ω9c	1.9	17.769
46381	C18:2 ω6,9c/C18:0 ANTE	4.2	17.724
46381	C19:0 ANTEISO	1.5	18.729
46381	C19:0 ISO	0.5	18.633
46381	C20:2 ω6,9c	1.4	19.735

type of FA analysis: whole cell analysis
method/protocol: CCUG

API ID32STA

@ref	URE	ADH Arg	ODC	ESC	GLU	FRU	MNE	MAL	LAC	TRE	MAN	RAF	RIB	CEL	NIT	VP	beta GAL	ArgA	PAL	PyrA	NOVO	SAC	NAG	TUR	ARA	beta GUR
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+/-	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	-	+	+	-	+	+/-	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+/-	-	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+/-	+	+	+	-	-
1123	+/-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+/-	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	+	+	+	+	+	-	-
1123	+	+	-	-	+	+	+	+	+	+/-	+	-	-	-	+	+	-	-	+	+	+	+	+	-	-	-

Isolation, sampling and environmental information

isolation

@ref	sample type	country	origin.country	continent
1123	wound
46381	Wound
67770	Wound
116609	Human, Wound	United States of America	USA	North America

isolation source categories

Cat1: #Host Body-Site
Cat2: #Other
Cat3: #Wound

taxonmaps

@ref: 69479
File name: preview.99_3.png
url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_3;96_3;97_3;98_3;99_3&stattab=map
Last taxonomy: Staphylococcus
16S sequence: LC420068
Sequence Identity:
Total samples: 23199
soil counts: 353
aquatic counts: 991
animal counts: 21663
plant counts: 192

Safety information

risk assessment

@ref	pathogenicity human	pathogenicity animal	biosafety level	biosafety level comment
1123	yes	yes	2	Risk group (German classification)
116609			2	Risk group (French classification)

Sequence information

16S sequences

@ref: 67770
description: Staphylococcus aureus JCM 2874 gene for 16S ribosomal RNA, partial sequence
accession: LC420068
length: 1473
database: ena
NCBI tax ID: 1280

Genome sequences

@ref	description	accession	assembly level	database	NCBI tax ID
66792	Staphylococcus aureus ATCC 29213	GCA_001879295	contig	ncbi	1280
66792	Staphylococcus aureus ATCC 29213	GCA_001267715	contig	ncbi	1280
66792	Staphylococcus aureus strain NCTC12973	1280.18110	wgs	patric	1280
66792	Staphylococcus aureus strain SA29213-A	1280.26265	wgs	patric	1280
66792	Staphylococcus aureus strain SA29213-B	1280.26266	wgs	patric	1280
66792	Staphylococcus aureus subsp. aureus strain ATCC 29213	46170.287	wgs	patric	1280
66792	Staphylococcus aureus subsp. aureus strain ATCC 29213	46170.151	wgs	patric	1280
66792	Staphylococcus aureus aureus ATCC 29213	2648501387	draft	img	1280
66792	Staphylococcus aureus ATCC 29213	GCA_022832775	complete	ncbi	1280
66792	Staphylococcus aureus ATCC 29213	GCA_022870465	complete	ncbi	1280

Genome-based predictions

predictions

trait	prediction	confidence	training_data
spore-forming	yes	100	no
flagellated	no	91.507	no
gram-positive	yes	89.29	no
anaerobic	no	99.563	no
aerobic	yes	89.087	no
halophile	yes	93.772	no
spore-forming	no	93.589	no
motile	no	89.585	no
glucose-ferment	yes	87.623	no
thermophile	no	99.778	no
glucose-util	yes	89.047	no

External links

@ref: 1123

culture collection no.: CCUG 15915, DSM 2569, ATCC 29213, WDCM 00131, JCM 2874, CCM 4223, CECT 794, CIP 103429, IFO 15035, LMG 10147, NBIMCC 3999, NBRC 15035, NCTC 12973

straininfo link

@ref: 83592
straininfo: 4996

literature

topic	Pubmed-ID	title	authors	journal	DOI	year	mesh	topic2
Metabolism	1416840	Quinolone accumulation in Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.	McCaffrey C, Bertasso A, Pace J, Georgopapadakou NH	Antimicrob Agents Chemother	10.1128/AAC.36.8.1601	1992	4-Quinolones, Anti-Infective Agents/chemistry/metabolism, Chemical Phenomena, Chemistry, Physical, Escherichia coli/metabolism, Pseudomonas aeruginosa/metabolism, Staphylococcus aureus/metabolism
Pathogenicity	1521761	Improved method for electroporation of Staphylococcus aureus.	Schenk S, Laddaga RA	FEMS Microbiol Lett	10.1016/0378-1097(92)90596-g	1992	Cell Membrane Permeability, DNA, Bacterial/chemistry/pharmacology, Electric Conductivity, Freezing, Plasmids/genetics, Staphylococcus aureus/chemistry/genetics, Staphylococcus epidermidis/chemistry/genetics, Temperature, *Transformation, Genetic/drug effects
Pathogenicity	1810737	Antimicrobial activity of RU29246 (HR916 metabolite) compared with four other oral beta-lactams tested against more than 5000 clinical isolates.	Murray PR, Allen SD, Erwin ME, Gerlach EH, Jones RN, Koontz FP, Pfaller MA, Washington JA 2nd	Eur J Clin Microbiol Infect Dis	10.1007/BF01972510	1991	Amoxicillin/pharmacology, Amoxicillin-Potassium Clavulanate Combination, Cefaclor/pharmacology, Cefixime, Cefotaxime/analogs & derivatives/pharmacology, Cephalexin/pharmacology, Cephalosporins/pharmacology, Clavulanic Acids/pharmacology, Drug Therapy, Combination/pharmacology, Enterococcus/drug effects, Gram-Positive Bacteria/drug effects, Humans, Microbial Sensitivity Tests, Staphylococcus/drug effects, Streptococcus agalactiae/drug effects
Pathogenicity	1903912	In vitro activity of RP 59500, a semisynthetic injectable pristinamycin, against staphylococci, streptococci, and enterococci.	Fass RJ	Antimicrob Agents Chemother	10.1128/AAC.35.3.553	1991	Anti-Bacterial Agents/pharmacology, Enterobacteriaceae/drug effects, Kinetics, Microbial Sensitivity Tests, Staphylococcus/drug effects, Streptococcus/drug effects, Virginiamycin/*pharmacology	Enzymology
Pathogenicity	2060516	Interpretive criteria for disk diffusion susceptibility testing of sparfloxacin.	Kayser FH, Wust J	Eur J Clin Microbiol Infect Dis	10.1007/BF01964449	1991	Anti-Infective Agents/pharmacology, Ciprofloxacin/pharmacology, Fluoroquinolones, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Microbial Sensitivity Tests, Regression Analysis
Pathogenicity	2093106	In-vitro postantibiotic effects of miocamycin and erythromycin on gram-positive cocci.	Varotto F, Garlaschi ML, Garlaschi MC, Falchi M, Scaglione F, Cattaneo G, De Luca M, Fraschini F	J Chemother	10.1080/1120009x.1990.11739043	1990	Adult, Colony Count, Microbial, Erythromycin/pharmacology, Gram-Positive Bacteria/drug effects/growth & development, Humans, Miocamycin/pharmacology, Staphylococcus aureus/drug effects/growth & development, Streptococcus/drug effects/growth & development, Time Factors
Pathogenicity	2492304	Ofloxacin susceptibility testing quality control parameters for microdilution and disk diffusion, and confirmation of disk diffusion interpretive criteria.	Fuchs PC, Jones RN, Barry AL, Gavan TL	J Clin Microbiol	10.1128/jcm.27.1.49-52.1989	1989	Bacteria/drug effects, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Microbial Sensitivity Tests/standards, Multicenter Studies as Topic, Ofloxacin/*pharmacology, Pseudomonas aeruginosa/drug effects, Quality Control, Staphylococcus aureus/drug effects
Pathogenicity	3098779	Quality control limits for microdilution susceptibility tests with norfloxacin.	Barry AL, Gavan TL, Ayers LW, Fuchs PC, Gerlach EH, Thornsberry C	J Clin Microbiol	10.1128/jcm.25.1.165-166.1987	1987	Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Microbial Sensitivity Tests/standards, Norfloxacin/pharmacology, Prospective Studies, Pseudomonas aeruginosa/drug effects, Quality Control, Staphylococcus aureus/*drug effects
Pathogenicity	3121667	Disk diffusion susceptibility testing and broth microdilution quality control guidelines for BMY-28100, a new orally administered cephalosporin.	Jones RN, Barry AL	J Clin Microbiol	10.1128/jcm.25.11.2211-2213.1987	1987	Cephalosporins/pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Haemophilus influenzae/drug effects, Microbial Sensitivity Tests/standards, Providencia/drug effects, Pseudomonas aeruginosa/drug effects, Quality Control, Regression Analysis, Staphylococcus aureus/drug effects
Pathogenicity	3145868	In vitro activity of FCE 22101, imipenem, and ceftazidime against over 6,000 bacterial isolates and MIC quality control limits of FCE 22101.	Barry AL, Aldridge KE, Allen SD, Fuchs PC, Gerlach EH, Jones RN, Pfaller MA	Eur J Clin Microbiol Infect Dis	10.1007/BF01975053	1988	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Carbapenems, Ceftazidime/pharmacology, Imipenem/pharmacology, Microbial Sensitivity Tests/standards, Quality Control
	3219818	An in vitro evaluation of HRE 664, a novel penem antibiotic.	Fuchs PC, Barry AL, Jones RN, Aldridge KE	Diagn Microbiol Infect Dis	10.1016/0732-8893(88)90071-5	1988	Anti-Bacterial Agents/pharmacology, Cefotaxime/pharmacology, Cephalosporins/pharmacology, Drug Resistance, Microbial, Drug Stability, *Lactams, Microbial Sensitivity Tests/standards, Quality Control, Temperature
Pathogenicity	3370932	Antimicrobial activity of U-76,252 (CS-807), a new orally administered cephalosporin ester, including recommendations for MIC quality control.	Jones RN, Barry AL, Pfaller M, Allen SD, Ayers LW, Fuchs PC	Diagn Microbiol Infect Dis	10.1016/0732-8893(88)90063-6	1988	Administration, Oral, Cefaclor/pharmacology, Ceftizoxime/analogs & derivatives, Cephalexin/pharmacology, Cephalosporins/administration & dosage/pharmacology/standards, Cephradine/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Humans, Microbial Sensitivity Tests, Quality Control
	3980689	Effects of storage temperature and pH on the stability of eleven beta-lactam antibiotics in MIC trays.	Nickolai DJ, Lammel CJ, Byford BA, Morris JH, Kaplan EB, Hadley WK, Brooks GF	J Clin Microbiol	10.1128/jcm.21.3.366-370.1985	1985	Anti-Bacterial Agents/pharmacology, Drug Stability, Drug Storage, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Temperature, beta-Lactams
Pathogenicity	7629792	Synthesis and antibacterial activity of some novel 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. Potent antistaphylococcal agents.	Reuman M, Daum SJ, Singh B, Wentland MP, Perni RB, Pennock P, Carabateas PM, Gruett MD, Saindane MT, Dorff PH, et al.	J Med Chem	10.1021/jm00014a005	1995	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Bacillus/drug effects, Carboxylic Acids/chemical synthesis/chemistry/pharmacology, Enterococcus faecalis/drug effects, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/*drug effects, Streptococcus pneumoniae/drug effects, Structure-Activity Relationship
Enzymology	7726522	Effect of aerobic and anaerobic environments on antistaphylococcal activities of five fluoroquinolones.	Zabinski RA, Walker KJ, Larsson AJ, Moody JA, Kaatz GW, Rotschafer JC	Antimicrob Agents Chemother	10.1128/AAC.39.2.507	1995	Anaerobiosis, Anti-Infective Agents/pharmacokinetics/pharmacology, Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology, Ciprofloxacin/pharmacology, Fluoroquinolones, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Ofloxacin/pharmacology, Quinolones/pharmacology, Staphylococcus aureus/*drug effects	Pathogenicity
Enzymology	7764190	Separation and isolation of viable bacteria by capillary zone electrophoresis.	Ebersole RC, McCormick RM	Biotechnology (N Y)	10.1038/nbt1193-1278	1993	Electrophoresis/methods, Enterococcus faecalis/growth & development/isolation & purification, Staphylococcus aureus/growth & development/isolation & purification, Streptococcus/growth & development/*isolation & purification, Streptococcus agalactiae/growth & development/isolation & purification, Streptococcus pneumoniae/growth & development/isolation & purification, Streptococcus pyogenes/growth & development/isolation & purification	Phylogeny
Pathogenicity	7956017	Minimum inhibitory concentration quality-control guidelines for biapenem, DU-6859a, FK-037, levofloxacin, grepafloxacin, and ceftizoxime when using various National Committee for Clinical Laboratory Standards susceptibility test methods. Quality Control Study Group.	Bale MJ, Jones RN, Erwin ME	Diagn Microbiol Infect Dis	10.1016/0732-8893(94)90054-x	1994	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Bacteria/drug effects, Ceftizoxime/analogs & derivatives/pharmacology, Fluoroquinolones, Levofloxacin, Microbial Sensitivity Tests/standards, Ofloxacin/pharmacology, Piperazines/pharmacology, Quality Control, Quinolones/pharmacology, Reference Values, Spiro Compounds/pharmacology, Thienamycins/pharmacology
Enzymology	8089069	Microbiological tests to predict treatment outcome in experimental device-related infections due to Staphylococcus aureus.	Zimmerli W, Frei R, Widmer AF, Rajacic Z	J Antimicrob Chemother	10.1093/jac/33.5.959	1994	Animals, Anti-Bacterial Agents/pharmacokinetics/pharmacology/therapeutic use, Bacterial Adhesion, Male, Microbial Sensitivity Tests, Prognosis, Prosthesis-Related Infections/drug therapy/microbiology, Rats, Staphylococcal Infections/drug therapy/microbiology, Treatment Outcome
Metabolism	8198105	The contribution of vitamin K2 (menaquinones) produced by the intestinal microflora to human nutritional requirements for vitamin K.	Conly JM, Stein K, Worobetz L, Rutledge-Harding S	Am J Gastroenterol		1994	Adult, Bacteria/metabolism, Factor VII/analysis, Humans, Ileum/metabolism/microbiology, Male, Nutritional Requirements, Prothrombin/analysis, Prothrombin Time, Staphylococcus aureus/metabolism, Vitamin K/administration & dosage/*analogs & derivatives/biosynthesis/metabolism/pharmacology, Vitamin K 1/blood, Vitamin K 2/analogs & derivatives	Pathogenicity
Pathogenicity	8241071	Production of staphylococcal impetigo-like lesion on human skin explants in culture.	Abe Y, Akiyama H, Arata J	J Dermatol Sci	10.1016/0923-1811(93)90762-e	1993	Adult, Child, Preschool, Culture Techniques, Fluorescent Antibody Technique, Humans, Impetigo/pathology, Male, Microscopy, Electron, Mouth Mucosa/pathology, Skin/pathology, Staphylococcal Infections/*pathology	Biotechnology
	8272327	[Reproducible model of a bacterial conjunctivitis].	Behrens-Baumann W, Begall T	Ophthalmologica	10.1159/000310366	1993	Animals, Conjunctiva/microbiology/pathology/surgery, *Conjunctivitis, Bacterial/complications/pathology, Disease Models, Animal, Haemophilus Infections, Haemophilus influenzae, Hyperemia/etiology, Injections, Rabbits, Reproducibility of Results, Staphylococcal Infections, Staphylococcus aureus, Staphylococcus epidermidis, Suppuration
Pathogenicity	8273272	The inhibition by ionophores in vitro of an Enterococcus-like pathogen of rainbow trout, Oncorhynchus mykiss.	Carson J, Statham P	Vet Microbiol	10.1016/0378-1135(93)90092-l	1993	Animals, Anti-Bacterial Agents/pharmacology, Enterococcus/drug effects, Erythromycin/pharmacology, Fish Diseases/microbiology, Gram-Positive Bacterial Infections/microbiology/veterinary, Ionophores/pharmacology, Lasalocid/pharmacology, Microbial Sensitivity Tests/veterinary, Monensin/pharmacology, Oncorhynchus mykiss/*microbiology, Pyrans/pharmacology
Pathogenicity	8595095	Synthesis and antimicrobial activity of substituted benzimidazole, benzothiazole and imidazole derivatives.	Kucukbay H, Cetinkaya E, Durmaz R	Arzneimittelforschung		1995	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Benzimidazoles/chemical synthesis/pharmacology, Benzothiazoles, Imidazoles/chemical synthesis/pharmacology, Indicators and Reagents, Magnetic Resonance Spectroscopy, Mass Spectrometry, Microbial Sensitivity Tests, Spectrophotometry, Infrared, Thiazoles/chemical synthesis/pharmacology
Enzymology	8787872	Ex vivo antibacterial properties of rufloxacin compared with those of norfloxacin in a study with healthy volunteers.	Aguilar L, Balcabao IP, Salva P, Martin M, Costa J, Prieto J, Dal-re R	Antimicrob Agents Chemother	10.1128/AAC.40.1.17	1996	Adult, Anti-Infective Agents/pharmacokinetics/pharmacology/urine, Bacteriuria/drug therapy/microbiology, Cross-Over Studies, Escherichia coli Infections/drug therapy/urine, Fluoroquinolones, Humans, Male, Microbial Sensitivity Tests, Norfloxacin/pharmacokinetics/pharmacology/urine, Quinolones/pharmacokinetics/*pharmacology/urine, Serum Bactericidal Test, Staphylococcal Infections/drug therapy/urine	Pathogenicity
Pathogenicity	8818906	Proposed MIC quality control guidelines for National Committee for Clinical Laboratory Standards susceptibility tests using seven veterinary antimicrobial agents: ceftiofur, enrofloxacin, florfenicol, penicillin G-novobiocin, pirlimycin, premafloxacin, and spectinomycin.	Marshall SA, Jones RN, Wanger A, Washington JA, Doern GV, Leber AL, Haugen TH	J Clin Microbiol	10.1128/jcm.34.8.2027-2029.1996	1996	Anti-Bacterial Agents/pharmacology, Dose-Response Relationship, Drug, Enterobacteriaceae/drug effects, Laboratories, Microbial Sensitivity Tests/standards/veterinary, Pseudomonas aeruginosa/drug effects, Quality Control, Staphylococcus aureus/drug effects
Pathogenicity	8843303	Comparison of three different in vitro methods of detecting synergy: time-kill, checkerboard, and E test.	White RL, Burgess DS, Manduru M, Bosso JA	Antimicrob Agents Chemother	10.1128/AAC.40.8.1914	1996	Bacteria/drug effects, Cefepime, Ceftazidime/pharmacology, Cephalosporins/pharmacology, Ciprofloxacin/pharmacology, Drug Synergism, Drug Therapy, Combination/pharmacology, Enterobacter cloacae/drug effects, Escherichia coli/drug effects, Microbial Sensitivity Tests/methods, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Tobramycin/pharmacology
Pathogenicity	8849237	In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents.	Zurenko GE, Yagi BH, Schaadt RD, Allison JW, Kilburn JO, Glickman SE, Hutchinson DK, Barbachyn MR, Brickner SJ	Antimicrob Agents Chemother	10.1128/AAC.40.4.839	1996	Acetamides/pharmacology, Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Drug Resistance, Microbial, Linezolid, Microbial Sensitivity Tests, Oxazoles/pharmacology, *Oxazolidinones, Vancomycin/pharmacology
Enzymology	8937954	The concentration-independent effect of monoexponential and biexponential decay in vancomycin concentrations on the killing of Staphylococcus aureus under aerobic and anaerobic conditions.	Larsson AJ, Walker KJ, Raddatz JK, Rotschafer JC	J Antimicrob Chemother	10.1093/jac/38.4.589	1996	Aerobiosis, Anaerobiosis, Anti-Bacterial Agents/pharmacokinetics/pharmacology, Half-Life, Logistic Models, Microbial Sensitivity Tests, Regression Analysis, Staphylococcus aureus/drug effects, Vancomycin/pharmacokinetics/*pharmacology	Pathogenicity
Pathogenicity	9006791	Synthesis and antimicrobial activity of electron rich olefin derived cyclic ureas.	Cetinkaya B, Cetinkaya E, Kucukbay H, Durmaz R	Arzneimittelforschung		1996	Alkenes/chemical synthesis/pharmacology, Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Magnetic Resonance Spectroscopy, Mass Spectrometry, Microbial Sensitivity Tests, Spectrophotometry, Infrared, Urea/analogs & derivatives/*chemical synthesis/pharmacology
Pathogenicity	9125286	Antimicrobial activity of carbene complexes of rhodium(I) and ruthenium(II).	Cetinkaya B, Cetinkaya E, Kucukbay H, Durmaz R	Arzneimittelforschung		1996	Ampicillin/pharmacology, Anti-Bacterial Agents/pharmacology, Benzimidazoles/chemistry/pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Hydrocarbons, Methane/analogs & derivatives/chemistry, Microbial Sensitivity Tests, Penicillins/pharmacology, Pseudomonas aeruginosa/drug effects, Rhodium/chemistry/pharmacology, Ruthenium/chemistry/pharmacology, Staphylococcus aureus/*drug effects
Pathogenicity	9150863	Synthesis and antimicrobial activity of 1-dialkylaminomethyl- 2-(p-substituted phenyl)-5-substituted benzimidazole derivatives.	Ersan S, Nacak S, Acar N, Noyanalpan N	Arzneimittelforschung		1997	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Benzimidazoles/chemical synthesis/pharmacology, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Spectrophotometry, Infrared, Sulfides
Pathogenicity	9239458	Synthesis and antimicrobial activity of beta-[(2-benzimidazolyl)thio]-beta-benzoyl styrene derivatives.	Ersan S, Nacak S, Acar N, Ozden T	Arzneimittelforschung		1997	Anti-Bacterial Agents/chemical synthesis/pharmacology, Benzimidazoles/chemical synthesis/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Microbial Sensitivity Tests, Structure-Activity Relationship, Styrenes/chemical synthesis/*pharmacology
Pathogenicity	9248647	Does tea tree oil have a place in the topical treatment of burns?	Faoagali J, George N, Leditschke JF	Burns	10.1016/s0305-4179(96)00130-1	1997	Anti-Infective Agents, Local/pharmacology, Bacteria/drug effects, Burns/drug therapy, Enterococcus faecalis/drug effects/physiology, Escherichia coli/drug effects/physiology, Humans, Microbial Sensitivity Tests, Oils, Volatile/pharmacology, Plant Oils/*pharmacology, Plants, Medicinal, Pseudomonas aeruginosa/drug effects/physiology, Staphylococcus aureus/drug effects/physiology, Tea Tree Oil, Triclosan/pharmacology
Enzymology	9271816	A novel variant of staphylokinase gene from Staphylococcus aureus ATCC 29213.	Kim SH, Chun HS, Han MH, Park NY, Suk K	Thromb Res	10.1016/s0049-3848(97)00142-4	1997	Amino Acid Sequence, Base Sequence, Cloning, Molecular, DNA, Complementary/genetics/isolation & purification, Genes, Bacterial, Metalloendopeptidases/genetics, Molecular Sequence Data, Sequence Alignment, Staphylococcus aureus/*genetics	Genetics
Phylogeny	9294704	In vitro antimicrobial activity and MIC quality control guidelines of RPR 106972 (RPR 112808/RPR106950): a novel orally administered streptogramin combination. The Quality Control Study Group.	Putnam SD, Jones RN, Johnson DM	Diagn Microbiol Infect Dis	10.1016/s0732-8893(97)00023-0	1997	Administration, Oral, Anti-Bacterial Agents/pharmacology, Drug Combinations, Drug Resistance, Microbial, Enterococcus/drug effects/isolation & purification, Gram-Negative Bacteria/drug effects/isolation & purification, Gram-Positive Cocci/drug effects/isolation & purification, Guidelines as Topic, Humans, Microbial Sensitivity Tests/standards, Quality Control, Species Specificity, Virginiamycin/pharmacology	Pathogenicity
Pathogenicity	9296284	Synthesis and antimicrobial activities of 2-[(alpha-methylbenzylidene)-hydrazino]benzoxazoles.	Ersan S, Nacak S, Berkem R, Ozden T	Arzneimittelforschung		1997	Anti-Bacterial Agents, Anti-Infective Agents/chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Benzoxazoles/chemical synthesis/pharmacology, Benzylidene Compounds/chemical synthesis/pharmacology, Candida/drug effects, Chemical Phenomena, Chemistry, Physical, Culture Media, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Spectrophotometry, Infrared	Cultivation
Pathogenicity	9542929	Characterization of staphylococci with reduced susceptibilities to vancomycin and other glycopeptides.	Tenover FC, Lancaster MV, Hill BC, Steward CD, Stocker SA, Hancock GA, O'Hara CM, McAllister SK, Clark NC, Hiramatsu K	J Clin Microbiol	10.1128/JCM.36.4.1020-1027.1998	1998	Anti-Bacterial Agents/pharmacology, Drug Resistance, Microbial, Microbial Sensitivity Tests, Polymerase Chain Reaction, Staphylococcus/drug effects, Vancomycin/*pharmacology
Pathogenicity	9553688	Antibacterial activity of rhodium, iridium, and ruthenium tripodal phosphine complexes.	Sulu M, Kucukbay H, Durmaz R, Gunal S	Arzneimittelforschung		1998	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Chemical Phenomena, Chemistry, Physical, Iridium/pharmacology, Microbial Sensitivity Tests, Molecular Conformation, Organometallic Compounds/*chemical synthesis/pharmacology, Rhodium/pharmacology, Ruthenium/pharmacology
Pathogenicity	9612603	Antibacterial activity of peritoneal exudate in patients treated with 2 g cefotiam for surgical anti-microbial prophylaxis.	Miglioli PA, Schoeffel U, Gabroska E, Allerberger F	Chemotherapy	10.1159/000007108	1998	Antibiotic Prophylaxis, Ascitic Fluid/chemistry/microbiology, Bacterial Infections/prevention & control, Cefotiam/administration & dosage/pharmacokinetics/pharmacology, Cephalosporins/administration & dosage/pharmacokinetics/*pharmacology, Escherichia coli/drug effects, Humans, In Vitro Techniques, Klebsiella pneumoniae/drug effects, Postoperative Complications/prevention & control, Proteus/drug effects, Staphylococcus aureus/drug effects	Enzymology
Enzymology	10049285	Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess.	Fernandez J, Barrett JF, Licata L, Amaratunga D, Frosco M	Antimicrob Agents Chemother	10.1128/AAC.43.3.667	1999	Abscess/drug therapy/microbiology, Animals, Anti-Infective Agents/pharmacokinetics/therapeutic use, Area Under Curve, Ciprofloxacin/pharmacokinetics/therapeutic use, Female, Levofloxacin, Microbial Sensitivity Tests, Ofloxacin/pharmacokinetics/therapeutic use, Rabbits, Staphylococcal Skin Infections/drug therapy/microbiology
Pathogenicity	10325322	The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms.	Ceri H, Olson ME, Stremick C, Read RR, Morck D, Buret A	J Clin Microbiol	10.1128/JCM.37.6.1771-1776.1999	1999	Alberta, Anti-Bacterial Agents/pharmacology, Biofilms, Escherichia coli/drug effects/growth & development/ultrastructure, Laboratories/standards, Microbial Sensitivity Tests/instrumentation/methods/standards, Pseudomonas aeruginosa/drug effects/growth & development, Quality Control, Reproducibility of Results, Sensitivity and Specificity, Staphylococcus aureus/*drug effects/growth & development
Pathogenicity	10326736	New derivatives of benzimidazole and their antimicrobial activity.	Cetinkaya E, Alici B, Gok Y, Durmaz R, Gunal S	J Chemother	10.1179/joc.1999.11.2.83	1999	Anti-Bacterial Agents/pharmacology, Benzimidazoles/pharmacology, Dose-Response Relationship, Drug, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects
Pathogenicity	10348766	In vitro activities of designed antimicrobial peptides against multidrug-resistant cystic fibrosis pathogens.	Schwab U, Gilligan P, Jaynes J, Henke D	Antimicrob Agents Chemother	10.1128/AAC.43.6.1435	1999	Amino Acid Sequence, Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Cystic Fibrosis/microbiology, Drug Resistance, Microbial, Drug Resistance, Multiple, Humans, Microbial Sensitivity Tests, Molecular Sequence Data, Osmolar Concentration, Peptides	Genetics
Pathogenicity	10354859	Antimicrobial activity and spectrum of SCH27899 (Ziracin) tested against gram-positive species including recommendations for routine susceptibility testing methods and quality control. Quality Control Study Group.	Jones RN, Marshall SA, Erwin ME	Diagn Microbiol Infect Dis	10.1016/s0732-8893(98)00093-5	1999	Aminoglycosides, Anti-Bacterial Agents/pharmacology, Gram-Positive Bacteria/*drug effects, Gram-Positive Bacterial Infections/microbiology, Humans, Laboratories/standards, Microbial Sensitivity Tests/methods/standards, Quality Control, Reference Standards
Pathogenicity	10417872	Antibacterial and antifungal activities of complexes of ruthenium (II).	Cetinkaya B, Ozdemir I, Binbasioglu B, Durmaz R, Gunal S	Arzneimittelforschung	10.1055/s-0031-1300457	1999	Anti-Bacterial Agents, Anti-Infective Agents/pharmacology, Antifungal Agents/pharmacology, Bacteria/drug effects, Fungi/drug effects, Microbial Sensitivity Tests, Ruthenium Compounds/*pharmacology, Structure-Activity Relationship
Pathogenicity	10487435	Decontamination of human sclera: an in vitro study.	Lucci LM, Yu MC, Hofling-Lima AL	Cornea	00003226-199909000-00011	1999	Bacillus cereus/drug effects/growth & development, Benzalkonium Compounds/pharmacology, Colony Count, Microbial, Decontamination/methods, Drug Resistance, Microbial, Ethanol/pharmacology, Glycerol/pharmacology, Humans, Microbial Sensitivity Tests, Preservatives, Pharmaceutical/pharmacology, Pseudomonas aeruginosa/drug effects/growth & development, Sclera/microbiology, Staphylococcus aureus/drug effects/growth & development, Tissue Preservation
Pathogenicity	10638693	Staphylococcus aureus adherence to thrombin-treated endothelial cells is mediated by fibrinogen but not by platelets.	Shenkman B, Rubinstein E, Tamarin I, Dardik R, Savion N, Varon D	J Lab Clin Med	10.1016/s0022-2143(00)70019-9	2000	Alprostadil/pharmacology, Antibodies, Blocking/pharmacology, Bacterial Adhesion/drug effects, Blood Platelets/drug effects/physiology, Cells, Cultured, Dose-Response Relationship, Drug, Endothelium, Vascular/drug effects/microbiology, Fibrinogen/physiology, Fibronectins/pharmacology, Hirudins/pharmacology, Humans, Oligopeptides/pharmacology, Staphylococcus aureus/drug effects/physiology, Thrombin/pharmacology, von Willebrand Factor/pharmacology
Pathogenicity	10724025	Antimicrobial activity of synthetic all-D mastoparan M.	Li ML, Liao RW, Qiu JW, Wang ZJ, Wu TM	Int J Antimicrob Agents	10.1016/s0924-8579(99)00127-2	2000	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Circular Dichroism, Escherichia coli/drug effects/growth & development/ultrastructure, Microscopy, Electron, Scanning, Peptides/chemical synthesis/chemistry/pharmacology, Staphylococcus aureus/drug effects/growth & development/ultrastructure, Stereoisomerism, Wasp Venoms/chemical synthesis/chemistry/*pharmacology
Pathogenicity	10747825	Levofloxacin penetrates human monocytes and enhances intracellular killing of Staphylococcus aureus and Pseudomonas aeruginosa.	Smith RP, Baltch AL, Franke MA, Michelsen PB, Bopp LH	J Antimicrob Chemother	10.1093/jac/45.4.483	2000	Anti-Infective Agents/metabolism/pharmacokinetics/pharmacology, Blood Bactericidal Activity/drug effects, Humans, Hydrogen-Ion Concentration, In Vitro Techniques, Levofloxacin, Monocytes/metabolism/microbiology, Ofloxacin/metabolism/pharmacokinetics/pharmacology, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/*drug effects, Temperature	Metabolism
Cultivation	10929879	Evaluation of quinupristin/dalfopristin (Synercid) and RPR 106972 stability in susceptibility testing media.	Marshall SA, Kugler KC, Jones RN	Int J Antimicrob Agents	10.1016/s0924-8579(00)00180-1	2000	Anti-Bacterial Agents/pharmacology, Culture Media, Drug Therapy, Combination/pharmacology, Microbial Sensitivity Tests, Virginiamycin/pharmacology
Pathogenicity	10947319	Basis for nebulized antibiotics: droplet characterization and in vitro antimicrobial activity versus Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.	Todisco T, Eslami A, Baglioni S, Sposini T, Tascini C, Sommer E, Knoch M	J Aerosol Med	10.1089/jam.2000.13.11	2000	Aerosols, Anti-Bacterial Agents/administration & dosage/pharmacology, Escherichia coli/drug effects, Imipenem/administration & dosage/pharmacology, Microbial Sensitivity Tests, Nebulizers and Vaporizers, Particle Size, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Streptomycin/administration & dosage/pharmacology, Thienamycins/administration & dosage/pharmacology, Tobramycin/administration & dosage/*pharmacology
Metabolism	11112090	In vivo metabolism of 4-fluorobenzoic acid [(5-nitro-2-furanyl)methylene] hydrazide in rats.	Gulerman NN, Oruc EE, Kartal F, Rollas S	Eur J Drug Metab Pharmacokinet	10.1007/BF03190075	2000	Animals, Benzoates/metabolism, Chromatography, High Pressure Liquid, Hydrazones/metabolism, Male, Rats, Rats, Wistar
Pathogenicity	11173190	Comparative in vitro pharmacodynamics of imipenem and meropenem against ATCC strains of Escherichia coli, Staphylococcus aureus and Bacteroides fragilis.	White RL, Friedrich LV, Manduru M, Mihm LB, Bosso JA	Diagn Microbiol Infect Dis	10.1016/s0732-8893(00)00219-4	2001	Bacteroides fragilis/drug effects, Dose-Response Relationship, Drug, Drug Stability, Escherichia coli/drug effects, Imipenem/pharmacology, Meropenem, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects, Thienamycins/*pharmacology
Pathogenicity	11266409	Application of a spectrophotometric method for the determination of post-antibiotic effect and comparison with viable counts in agar.	Dominguez MC, de La Rosa M, Borobio MV	J Antimicrob Chemother	10.1093/jac/47.4.391	2001	Agar, Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Bacteria/drug effects/growth & development, Ciprofloxacin/pharmacology, Colony Count, Microbial, Escherichia coli/drug effects/growth & development, Gentamicins/pharmacology, Kinetics, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/growth & development, Spectrophotometry/methods, Staphylococcus aureus/drug effects/growth & development	Enzymology
Pathogenicity	11396253	[Experimental study of antiseptic (tauroline, taurolidine) and antibiotic (sulmycin implant) drugs in vascular prosthesis infections in a standardized infection model].	Hernandez-Richter T, Schardey HM, Heiss MM, Lohlein F, Schildberg FW	Zentralbl Chir	10.1055/s-2001-14758	2001	Animals, Anti-Infective Agents, Local/pharmacology, Blood Vessel Prosthesis, Collagen/analogs & derivatives/pharmacology, Femoral Artery/pathology, Gentamicins/pharmacology, Prosthesis-Related Infections/drug therapy/pathology, Staphylococcal Infections/drug therapy/pathology, Swine, Taurine/analogs & derivatives/pharmacology, Thiadiazines/*pharmacology
Pathogenicity	11413744	Synthesis of some benzimidazole derivatives and their antibacterial and antifungal activities.	Kucukbay H, Durmaz R, Guven M, Gunal S	Arzneimittelforschung	10.1055/s-0031-1300057	2001	Anti-Bacterial Agents, Anti-Infective Agents/chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Benzimidazoles/chemical synthesis/pharmacology, Candida/drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Spectroscopy, Fourier Transform Infrared, Structure-Activity Relationship
Pathogenicity	11448567	Validation of cefditoren MIC quality control ranges by a multi-laboratory study (2001).	Jones RN, Biedenbach DJ	Diagn Microbiol Infect Dis	10.1016/s0732-8893(01)00236-x	2001	Cephalosporins/pharmacology, Escherichia coli/drug effects, Haemophilus influenzae/drug effects, Humans, Laboratories/standards, Microbial Sensitivity Tests/standards, Microbiology, Quality Control, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects
Pathogenicity	11741112	Effect of sulfur hexafluoride gas on antibacterial activity of antibiotics in vitro against agents causing endophthalmitis.	Yanyali A, Cetin S, Talu H, Vahaboglu H	Ophthalmologica	10.1159/000050905	2001	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Cefazolin/pharmacology, Ceftazidime/pharmacology, Cephalosporins/pharmacology, Drug Synergism, Endophthalmitis/microbiology, Microbial Sensitivity Tests, Ofloxacin/pharmacology, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Sulfur Hexafluoride/*pharmacology, Tobramycin/pharmacology
Pathogenicity	11899052	Inhibition, resistance development, and increased antibiotic and antimicrobial resistance caused by nutraceuticals.	Ward P, Fasitsas S, Katz SE	J Food Prot	10.4315/0362-028x-65.3.528	2002	Ampicillin/pharmacology, Ampicillin Resistance, Drug Resistance, Bacterial, Echinacea/adverse effects, Escherichia coli/drug effects/growth & development, Garlic/adverse effects, Microbial Sensitivity Tests, Staphylococcus aureus/*drug effects/growth & development, Zinc/adverse effects
Pathogenicity	12072923	In vitro evaluation of the antibacterial activity of three different central venous catheters against gram-positive bacteria.	Yorganci K, Krepel C, Weigelt JA, Edmiston CE	Eur J Clin Microbiol Infect Dis	10.1007/s10096-002-0719-z	2002	Anti-Bacterial Agents/administration & dosage/pharmacology, Bacteremia/prevention & control, Bacterial Adhesion/drug effects, Catheterization, Central Venous/adverse effects, Colony Count, Microbial, Drug Combinations, Equipment Contamination/prevention & control, Gram-Positive Bacteria/drug effects, Humans, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Time Factors
Phylogeny	12112858	Identification and discrimination of Staphylococcus aureus strains using matrix-assisted laser desorption/ionization-time of flight mass spectrometry.	Bernardo K, Pakulat N, Macht M, Krut O, Seifert H, Fleer S, Hunger F, Kronke M	Proteomics	10.1002/1615-9861(200206)2:6<747::AID-PROT747>3.0.CO;2-V	2002	Electrophoresis, Gel, Pulsed-Field, Humans, Methicillin Resistance, Reproducibility of Results, Species Specificity, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, Staphylococcal Infections/microbiology, Staphylococcus aureus/classification/*metabolism	Enzymology
Pathogenicity	12120877	Remarkable substituent effects on antimicrobial activities of 1,3-diorganylimidazolidinium salts.	Cetinkaya E, Denizci A, Ozdemir I, Ozturk HT, Karaboz I, Cetinkaya B	J Chemother	10.1179/joc.2002.14.3.241	2002	Anti-Bacterial Agents, Anti-Infective Agents/chemistry/pharmacology/therapeutic use, Candida albicans/drug effects, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Humans, Imidazoles/chemistry/*pharmacology/therapeutic use, Microbial Sensitivity Tests, Structure-Activity Relationship
Pathogenicity	12149255	The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins.	Hoover DM, Boulegue C, Yang D, Oppenheim JJ, Tucker K, Lu W, Lubkowski J	J Biol Chem	10.1074/jbc.M203907200	2002	Amino Acid Sequence, Animals, Anti-Bacterial Agents, Anti-Infective Agents/chemistry/pharmacology, Chemokine CCL20, Chemokines, CC/chemistry, Dimerization, Escherichia coli/drug effects, Humans, Macrophage Inflammatory Proteins/chemistry, Mice, Microbial Sensitivity Tests, Models, Molecular, Molecular Sequence Data, Peptide Fragments, Protein Denaturation, Protein Folding, Protein Structure, Secondary, Receptors, CCR6, Receptors, Chemokine/chemistry, Recombinant Proteins/metabolism/pharmacology, Staphylococcus aureus/drug effects, beta-Defensins/chemistry/pharmacology	Genetics
Pathogenicity	12583435	Calibration of fusidic acid disk diffusion susceptibility testing of Staphylococcus areus.	Olsson-Liljequist B, Koljalg S, Karlsson I, Kronvall G	APMIS	10.1034/j.1600-0463.2002.1101002.x	2002	Anti-Bacterial Agents/pharmacology, Drug Resistance, Bacterial, Fusidic Acid/pharmacology, Humans, In Vitro Techniques, Microbial Sensitivity Tests/methods/statistics & numerical data, Regression Analysis, Staphylococcus aureus/drug effects/isolation & purification	Enzymology
	12767382	Synthesis, antibacterial and antifungal activities of electron-rich olefins derived benzimidazole compounds.	Kucukbay H, Durmaz R, Orhan E, Gunal S	Farmaco	10.1016/S0014-827X(03)00068-5	2003	Alkenes/chemical synthesis/pharmacology, Anti-Bacterial Agents/chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Benzimidazoles/chemical synthesis/pharmacology, *Electrons, Microbial Sensitivity Tests/methods
Enzymology	12791470	Target site bacterial killing of cefpirome and fosfomycin in critically ill patients.	Zeitlinger MA, Marsik C, Georgopoulos A, Muller M, Heinz G, Joukhadar C	Int J Antimicrob Agents	10.1016/s0924-8579(03)00047-5	2003	Anti-Bacterial Agents/administration & dosage/pharmacokinetics/pharmacology/therapeutic use, Cephalosporins/administration & dosage/pharmacokinetics/pharmacology/therapeutic use, Colony Count, Microbial, Drug Therapy, Combination/administration & dosage/pharmacokinetics/pharmacology/therapeutic use, Fosfomycin/administration & dosage/pharmacokinetics/pharmacology/therapeutic use, Humans, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/growth & development, Shock, Septic/drug therapy/metabolism/microbiology, Staphylococcus aureus/*drug effects/growth & development	Pathogenicity
Pathogenicity	12854364	Inhibition of the anti-staphylococcal activity of the antiseptic polihexanide by mucin.	Ansorg R, Rath PM, Fabry W	Arzneimittelforschung	10.1055/s-0031-1297121	2003	Anti-Infective Agents, Local/antagonists & inhibitors/pharmacology, Diffusion, Hexanes/antagonists & inhibitors/pharmacology, Microbial Sensitivity Tests, Mucins/pharmacology, Mucus/chemistry, Polymers/pharmacology, Staphylococcus/drug effects/growth & development
Pathogenicity	12960550	Bacterial reduction by cell salvage washing and leukocyte depletion filtration.	Waters JH, Tuohy MJ, Hobson DF, Procop G	Anesthesiology	10.1097/00000542-200309000-00021	2003	Blood/microbiology, Blood Preservation/methods, Cell Separation/methods, Colony Count, Microbial, Filtration, Humans, In Vitro Techniques, Leukocytes/physiology
Cultivation	14979611	Synthesis and antibacterial activities of new bis-benzimidazoles.	Kucukbay H, Durmaz R, Okuyucu N, Gunal S, Kazaz C	Arzneimittelforschung	10.1055/s-0031-1296938	2004	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects, Benzimidazoles/chemical synthesis/*pharmacology, Culture Media, Indicators and Reagents, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Spectrophotometry, Infrared, Spectroscopy, Fourier Transform Infrared, Structure-Activity Relationship	Pathogenicity
Enzymology	15120955	In vitro antimicrobial activity of orbifloxacin against Staphylococcus intermedius isolates from canine skin and ear infections.	Ganiere JP, Medaille C, Etore F	Res Vet Sci	10.1016/j.rvsc.2004.02.002	2004	Animals, Anti-Infective Agents/pharmacology, Ciprofloxacin/analogs & derivatives/pharmacology, Dog Diseases/microbiology, Dogs, Drug Resistance, Bacterial, Microbial Sensitivity Tests/veterinary, Otitis Externa/microbiology/veterinary, Pyoderma/microbiology/veterinary, Staphylococcal Skin Infections/microbiology/veterinary, Staphylococcus/drug effects/isolation & purification	Phylogeny
Metabolism	15183885	Differences in biofilm and planktonic cell mediated reduction of metalloid oxyanions.	Harrison JJ, Ceri H, Stremick C, Turner RJ	FEMS Microbiol Lett	10.1016/j.femsle.2004.05.005	2004	Animals, Biofilms/drug effects/growth & development, Culture Media, Drug Resistance, Bacterial, Metals, Heavy/metabolism/pharmacology, Oxidation-Reduction, Plankton/drug effects/growth & development/metabolism, Pseudomonas aeruginosa/drug effects/genetics/metabolism, Sodium Selenite/metabolism/pharmacology, Staphylococcus aureus/drug effects/growth & development/*metabolism, Tellurium/metabolism/pharmacology	Pathogenicity
Pathogenicity	15288924	Comparison of methods for antimicrobial susceptibility testing and MIC values for pleuromutilin drugs for Brachyspira hyodysenteriae isolated in Germany.	Rohde J, Kessler M, Baums CG, Amtsberg G	Vet Microbiol	10.1016/j.vetmic.2004.03.023	2004	Animals, Anti-Bacterial Agents/pharmacology, Diterpenes/pharmacology, Dysentery/microbiology/veterinary, Germany, Microbial Sensitivity Tests/methods/veterinary, Retrospective Studies, Spirochaetales/drug effects/isolation & purification, Spirochaetales Infections/microbiology/veterinary, Swine, Swine Diseases/*microbiology	Enzymology
Pathogenicity	15317502	Synthesis and characterization of human alpha-defensins 4-6.	Wu Z, Ericksen B, Tucker K, Lubkowski J, Lu W	J Pept Res	10.1111/j.1399-3011.2004.00179.x	2004	Amino Acid Sequence, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Chromatography, High Pressure Liquid, Escherichia coli/drug effects, Humans, Methods, Molecular Sequence Data, Oxidation-Reduction, Protein Folding, Spectrometry, Mass, Electrospray Ionization, Staphylococcus aureus/drug effects, alpha-Defensins/*chemical synthesis/chemistry/genetics/pharmacology	Genetics
Metabolism	15472003	Impact of plasma protein binding on antimicrobial activity using time-killing curves.	Zeitlinger MA, Sauermann R, Traunmuller F, Georgopoulos A, Muller M, Joukhadar C	J Antimicrob Chemother	10.1093/jac/dkh443	2004	Anti-Bacterial Agents/metabolism/pharmacology, Aza Compounds/metabolism/pharmacology, Blood Proteins/*metabolism, Fluoroquinolones, Microbial Sensitivity Tests, Moxifloxacin, Protein Binding, Quinolines/metabolism/pharmacology, Serum Albumin/metabolism
Metabolism	15488711	Light effect and reactive oxygen species in the action of ciprofloxacin on Staphylococcus aureus.	Becerra MC, Sarmiento M, Paez PL, Arguello G, Albesa I	J Photochem Photobiol B	10.1016/j.jphotobiol.2004.06.003	2004	Anti-Bacterial Agents/pharmacology, Ciprofloxacin/pharmacology, DNA Damage/radiation effects, Drug Resistance, Bacterial, Electrodes, Energy Transfer, Furans/metabolism, Light, Methionine/metabolism, Microbial Sensitivity Tests, Oxidation-Reduction, Oxidative Stress/drug effects/physiology, Phenalenes/metabolism, Reactive Oxygen Species/metabolism, Staining and Labeling, Staphylococcus aureus/drug effects/physiology/radiation effects, Time Factors, Ultraviolet Rays	Pathogenicity
Pathogenicity	15560820	Biofilm susceptibility to metal toxicity.	Harrison JJ, Ceri H, Stremick CA, Turner RJ	Environ Microbiol	10.1111/j.1462-2920.2004.00656.x	2004	Anti-Bacterial Agents/pharmacology, Biofilms/drug effects/growth & development, Cations/pharmacology, Escherichia coli/drug effects/growth & development, Metals/pharmacology, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/growth & development, Staphylococcus aureus/*drug effects/growth & development
Pathogenicity	15616286	Identification of novel inhibitors of bacterial translation elongation factors.	Jayasekera MM, Onheiber K, Keith J, Venkatesan H, Santillan A, Stocking EM, Tang L, Miller J, Gomez L, Rhead B, Delcamp T, Huang S, Wolin R, Bobkova EV, Shaw KJ	Antimicrob Agents Chemother	10.1128/AAC.49.1.131-136.2005	2005	Anti-Bacterial Agents/chemistry/pharmacology, Benzimidazoles/chemistry/pharmacology, Dipeptides/chemistry/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Cocci/drug effects, Guanidines/chemistry/pharmacology, Imidazoles/chemistry/pharmacology, Indoles/chemistry, Macromolecular Substances/metabolism, Microbial Sensitivity Tests, Peptide Elongation Factor Tu/antagonists & inhibitors/metabolism, Peptide Elongation Factors/antagonists & inhibitors/metabolism, Protein Biosynthesis/drug effects, Structure-Activity Relationship, Transcription, Genetic/drug effects	Metabolism
Pathogenicity	15808482	Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities.	Liang CH, Romero A, Rabuka D, Sgarbi PW, Marby KA, Duffield J, Yao S, Cheng ML, Ichikawa Y, Sears P, Hu C, Hwang SB, Shue YK, Sucheck SJ	Bioorg Med Chem Lett	10.1016/j.bmcl.2005.02.029	2005	Aminoglycosides/chemistry/pharmacology, Animals, Anti-Bacterial Agents/chemistry/pharmacology, Drug Evaluation, Preclinical, Female, Humans, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/isolation & purification, Structure-Activity Relationship	Enzymology
Pathogenicity	15931854	[Impact of Ph-SA on the expression of delta-toxin in Staphylococcus aureus].	Guo L, Zhang J, Tang XY, Qiu XQ	Sichuan Da Xue Xue Bao Yi Xue Ban		2005	Bacterial Proteins/genetics/pharmacology, Bacterial Toxins/biosynthesis, Humans, Pheromones/genetics/pharmacology, Pilot Projects, Staphylococcus aureus/drug effects/metabolism, Trans-Activators/genetics/*pharmacology	Metabolism
Enzymology	16182077	The effect of interlaboratory variability on antimicrobial susceptibility determination.	Annis DH, Craig BA	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2005.03.012	2005	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects/isolation & purification, Laboratories/standards, Microbial Sensitivity Tests/methods/standards, Microbiology, *Quality Control	Phylogeny
Pathogenicity	16195256	Cationic peptide of the male reproductive tract, HE2alpha, displays antimicrobial activity against Neisseria gonorrhoeae, Staphylococcus aureus and Enterococcus faecalis.	Liao M, Ruddock PS, Rizvi AS, Hall SH, French FS, Dillon JR	J Antimicrob Chemother	10.1093/jac/dki350	2005	Antigens, Surface/pharmacology, Antimicrobial Cationic Peptides/pharmacology, Colony Count, Microbial, Dose-Response Relationship, Drug, Enterococcus faecalis/drug effects, Glycopeptides/pharmacology, Humans, Microbial Sensitivity Tests, Neisseria gonorrhoeae/drug effects, Recombinant Proteins/pharmacology, Staphylococcus aureus/*drug effects, Time Factors
Pathogenicity	16209091	Flow cytometry analysis of the activity of disinfecting agents tested with Staphylococcus aureus and Escherichia coli.	Wozniak-Kosek A, Kawiak J	Pol J Microbiol		2005	Disinfectants/pharmacology, Escherichia coli/drug effects/growth & development, Flow Cytometry/methods, Propidium/metabolism, Staphylococcus aureus/drug effects/growth & development, Time Factors	Metabolism
Pathogenicity	16229118	Synthesis and evaluation of analgesic/ anti-inflammatory and antimicrobial activities of 3-substituted- 1,2,4-triazole-5-thiones.	Tozkoparan B, Kupeli E, Yesilada E, Isik S, Ozalp M, Ertan M	Arzneimittelforschung	10.1055/s-0031-1296901	2005	Analgesics/chemical synthesis/pharmacology, Animals, Anti-Infective Agents/chemical synthesis/pharmacology, Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Biological Assay, Carrageenan, Edema/chemically induced/prevention & control, Indicators and Reagents, Magnetic Resonance Spectroscopy, Male, Mice, Microbial Sensitivity Tests, Models, Molecular, Spectrophotometry, Infrared, Stomach Ulcer/chemically induced/prevention & control, Thiones/chemical synthesis/pharmacology, Triazoles/chemical synthesis/pharmacology
Enzymology	16229889	Analysis of the beta-lactamase plasmid of borderline methicillin-susceptible Staphylococcus aureus: focus on bla complex genes and cadmium resistance determinants cadD and cadX.	Massidda O, Mingoia M, Fadda D, Whalen MB, Montanari MP, Varaldo PE	Plasmid	10.1016/j.plasmid.2005.08.001	2005	Bacterial Proteins/chemistry/genetics, Base Sequence, Cadmium/physiology, Cloning, Molecular, Drug Resistance, Bacterial/genetics, Membrane Proteins/genetics, Methicillin Resistance/genetics, Molecular Sequence Data, Plasmids/genetics, Staphylococcus aureus/drug effects/enzymology/genetics, Transformation, Bacterial, beta-Lactamases/chemistry/*genetics	Genetics
	16242721	Wound healing potential of Cassia fistula on infected albino rat model.	Senthil Kumar M, Sripriya R, Vijaya Raghavan H, Sehgal PK	J Surg Res	10.1016/j.jss.2005.08.025	2005	Animals, Cassia/chemistry, Male, Phytotherapy, Plant Extracts/pharmacology, Plant Leaves/chemistry, Pseudomonas Infections/drug therapy, Rats, Rats, Wistar, Staphylococcal Infections/drug therapy, Surgical Wound Infection/drug therapy, Treatment Outcome, *Wound Healing
Enzymology	16377693	Pharmacodynamics of a new streptogramin, XRP 2868, in murine thigh and lung infection models.	Andes D, Craig WA	Antimicrob Agents Chemother	10.1128/AAC.50.1.243-249.2006	2006	Animals, Anti-Infective Agents/pharmacokinetics/therapeutic use, Area Under Curve, Bacteria/drug effects, Bacterial Infections/drug therapy/metabolism/microbiology, Disease Models, Animal, Drug Combinations, Drug Evaluation, Lung/microbiology, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Streptogramin A/pharmacokinetics/therapeutic use, Streptogramin B/pharmacokinetics/therapeutic use, Streptogramins/pharmacokinetics/therapeutic use, Thigh/microbiology	Pathogenicity
Pathogenicity	16541200	Lipids and DNA oxidation in Staphylococcus aureus as a consequence of oxidative stress generated by ciprofloxacin.	Becerra MC, Paez PL, Larovere LE, Albesa I	Mol Cell Biochem	10.1007/s11010-005-9051-0	2006	Anti-Infective Agents/pharmacology, Ciprofloxacin/pharmacology, DNA Damage/drug effects, DNA, Bacterial/drug effects/metabolism, Drug Resistance, Humans, Lipid Peroxidation/drug effects, Luminescent Measurements, Malondialdehyde/metabolism, Oxidative Stress, Reactive Oxygen Species/pharmacology, Staphylococcus aureus/*drug effects/metabolism	Metabolism
Enzymology	16569855	Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target.	Andes D, Craig WA	Antimicrob Agents Chemother	10.1128/AAC.50.4.1376-1383.2006	2006	Animals, Butyrates/pharmacokinetics/pharmacology/therapeutic use, Female, Methicillin Resistance, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Oxazoles/pharmacokinetics/pharmacology/therapeutic use, Pneumonia, Bacterial/drug therapy, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects, Thigh/microbiology	Pathogenicity
Pathogenicity	16621461	Treatment of implant-associated infections with moxifloxacin: an animal study.	Kalteis T, Beckmann J, Schroder HJ, Schaumburger J, Linde HJ, Lerch K, Lehn N	Int J Antimicrob Agents	10.1016/j.ijantimicag.2005.12.003	2006	Animals, Anti-Bacterial Agents/therapeutic use, Aza Compounds/therapeutic use, Biofilms/drug effects, Fluoroquinolones, Implants, Experimental, Male, Moxifloxacin, Osteomyelitis/drug therapy, Quinolines/therapeutic use, Rats, Rats, Wistar, Staphylococcal Infections/drug therapy, Vancomycin/therapeutic use
Pathogenicity	16713190	Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests.	Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF	Int J Antimicrob Agents	10.1016/j.ijantimicag.2006.01.008	2006	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Microbial Sensitivity Tests/methods, Mouth Diseases/microbiology, Silver/pharmacology, Zinc/pharmacology
Pathogenicity	16735429	Consistent rates of kill of Staphylococcus aureus by gentamicin over a 6-fold clinical concentration range in an in vitro pharmacodynamic model (IVPDM).	Schafer JA, Hovde LB, Rotschafer JC	J Antimicrob Chemother	10.1093/jac/dkl216	2006	Anti-Bacterial Agents/pharmacology, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Gentamicins/pharmacology, Microbial Sensitivity Tests, Staphylococcus aureus/*drug effects/physiology
Enzymology	16752296	Moxifloxacin superior to vancomycin for treatment of bone infections--a study in rats.	Kalteis T, Beckmann J, Schroder HJ, Handel M, Grifka J, Lehn N, Lerch K	Acta Orthop	10.1080/17453670610046082	2006	Animals, Anti-Bacterial Agents/therapeutic use, Aza Compounds/therapeutic use, Drug Resistance, Bacterial, Femur/microbiology, Fluoroquinolones, Male, Moxifloxacin, Osteomyelitis/drug therapy/microbiology, Quinolines/therapeutic use, Rats, Rats, Wistar, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects/isolation & purification, Vancomycin/therapeutic use	Phylogeny
Pathogenicity	16870751	Comparative pharmacodynamics of gentamicin against Staphylococcus aureus and Pseudomonas aeruginosa.	Tam VH, Kabbara S, Vo G, Schilling AN, Coyle EA	Antimicrob Agents Chemother	10.1128/AAC.01165-05	2006	Anti-Bacterial Agents/pharmacology, Colony Count, Microbial, Dose Fractionation, Radiation, Dose-Response Relationship, Drug, Gentamicins/pharmacology, Humans, In Vitro Techniques, Kinetics, Microbial Sensitivity Tests, Models, Biological, Models, Statistical, Pseudomonas aeruginosa/drug effects/genetics/growth & development/isolation & purification, Reproducibility of Results, Staphylococcus aureus/drug effects/genetics/isolation & purification, Time Factors	Enzymology
Pathogenicity	17065618	Serum bactericidal activities of high-dose daptomycin with and without coadministration of gentamicin against isolates of Staphylococcus aureus and Enterococcus species.	DeRyke CA, Sutherland C, Zhang B, Nicolau DP, Kuti JL	Antimicrob Agents Chemother	10.1128/AAC.00290-06	2006	Adolescent, Adult, Anti-Bacterial Agents/administration & dosage/pharmacokinetics/pharmacology, Chromatography, High Pressure Liquid, Cross-Over Studies, Daptomycin/administration & dosage/pharmacokinetics/pharmacology, Drug Interactions, Drug Resistance, Bacterial, Enterococcus/drug effects, Female, Gentamicins/administration & dosage/pharmacokinetics/pharmacology, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Serum Bactericidal Test, Staphylococcus aureus/*drug effects	Enzymology
Pathogenicity	17174046	Bismuth-norfloxacin complex: synthesis, physicochemical and antimicrobial evaluation.	Shaikh AR, Giridhar R, Yadav MR	Int J Pharm	10.1016/j.ijpharm.2006.11.037	2006	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacillus/drug effects/growth & development, Calorimetry, Differential Scanning, Drug Combinations, Escherichia coli/drug effects/growth & development, Hydrogen-Ion Concentration, Klebsiella pneumoniae/drug effects/growth & development, Microbial Sensitivity Tests, Molecular Structure, Norfloxacin/analogs & derivatives/chemical synthesis/pharmacology, Organometallic Compounds/chemical synthesis/pharmacology, Solubility, Spectrophotometry, Atomic, Spectrophotometry, Infrared, Spectrophotometry, Ultraviolet, Staphylococcus aureus/drug effects/growth & development, Staphylococcus epidermidis/drug effects/growth & development, Temperature, Thermogravimetry, Titrimetry
Pathogenicity	17205689	[Investigation of the efficacy of electrolyzed acid water on the standard strains of some pathogenic microorganisms].	Ileri C, Sezen Y, Dimoglo A	Mikrobiyol Bul		2006	Candida albicans/drug effects/physiology, Chlorides/analysis, Disinfection/methods, Electrolysis, Hydrogen-Ion Concentration, Oxidation-Reduction, Pseudomonas aeruginosa/drug effects/physiology, Staphylococcus aureus/drug effects/physiology, Water/*chemistry/pharmacology
Pathogenicity	17485184	Identification of antibacterial constituents from the indigenous Australian medicinal plant Eremophila duttonii F. Muell. (Myoporaceae).	Smith JE, Tucker D, Watson K, Jones GL	J Ethnopharmacol	10.1016/j.jep.2007.03.031	2007	Anti-Bacterial Agents/chemistry/pharmacology, Australia, Biological Assay, Chromatography, Thin Layer, Hexanes, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Myoporaceae/*chemistry, Solvents, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Streptococcus pneumoniae/drug effects
Pathogenicity	17485797	Antibiotic susceptibility of potentially probiotic vaginal lactobacilli.	Ocana V, Silva C, Nader-Macias ME	Infect Dis Obstet Gynecol	10.1155/IDOG/2006/18182	2006	Agar, Anti-Bacterial Agents/pharmacology, Culture Media, Drug Resistance, Bacterial, Female, Humans, Lactobacillus/classification/drug effects/growth & development, Microbial Sensitivity Tests/methods/standards, Probiotics, Vagina/microbiology	Cultivation
Enzymology	17502404	Efficacy of a novel rifamycin derivative, ABI-0043, against Staphylococcus aureus in an experimental model of foreign-body infection.	Trampuz A, Murphy CK, Rothstein DM, Widmer AF, Landmann R, Zimmerli W	Antimicrob Agents Chemother	10.1128/AAC.00120-07	2007	Animals, Anti-Bacterial Agents/administration & dosage/chemistry/pharmacokinetics/therapeutic use, Colony Count, Microbial, Disease Models, Animal, Drug Therapy, Combination, Foreign-Body Reaction/drug therapy, Guinea Pigs, Injections, Intraperitoneal, Levofloxacin, Male, Microbial Sensitivity Tests, Molecular Structure, Ofloxacin/therapeutic use, Rifampin/administration & dosage/pharmacokinetics/therapeutic use, Rifamycins/administration & dosage/chemistry/pharmacokinetics/therapeutic use, Staphylococcal Infections/drug therapy, Staphylococcus aureus/*drug effects, Time Factors	Pathogenicity
Enzymology	17631925	Antimicrobial compounds from Eremophila serrulata.	Ndi CP, Semple SJ, Griesser HJ, Pyke SM, Barton MD	Phytochemistry	10.1016/j.phytochem.2007.05.039	2007	Anti-Infective Agents/chemistry/isolation & purification/pharmacology, Diterpenes/chemistry/isolation & purification/pharmacology, Eremophila Plant/chemistry, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Molecular Structure, Naphthalenes/chemistry/isolation & purification/pharmacology, Plant Leaves/chemistry, Plant Preparations, Pyrones/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects, Streptococcus pyogenes/drug effects	Phylogeny
Pathogenicity	17670919	Factors influencing broth microdilution antimicrobial susceptibility test results for dalbavancin, a new glycopeptide agent.	Rennie RP, Koeth L, Jones RN, Fritsche TR, Knapp CC, Killian SB, Goldstein BP	J Clin Microbiol	10.1128/JCM.02411-06	2007	Anti-Bacterial Agents/pharmacology, Humans, Microbial Sensitivity Tests/methods, Staphylococcus aureus/drug effects, Streptococcus/drug effects, Teicoplanin/*analogs & derivatives/pharmacology
	17719807	Laparoscopic diagnosis and treatment of aortic vascular prosthetic graft infections in a porcine model.	Gao H, Lund L, Prag J, Sandermann J, Lindholt JS	Eur J Vasc Endovasc Surg	10.1016/j.ejvs.2007.07.005	2007	Animals, Anti-Bacterial Agents/administration & dosage/therapeutic use, Aorta/surgery, Blood Vessel Prosthesis/adverse effects, Blood Vessel Prosthesis Implantation/instrumentation, Ciprofloxacin/therapeutic use, Debridement, Disease Models, Animal, Drug Therapy, Combination, Feasibility Studies, Female, Laparoscopy, Prosthesis-Related Infections/diagnosis/drug therapy/surgery, Rifampin/therapeutic use, *Staphylococcal Infections/diagnosis/drug therapy/surgery, Swine, Time Factors
Enzymology	17822333	[Species-identification and antimicrobial susceptibility tests by the fully automated RAISUS using an early-harvested cell suspension].	Nakasone I, Kisanuki K, Higa M, Kinjo T, Yamane N	Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi		2006	Automation, Bacteriological Techniques/instrumentation, Enterococcus faecalis/isolation & purification, Escherichia coli/isolation & purification, Microbial Sensitivity Tests/instrumentation, Pseudomonas aeruginosa, Staphylococcus aureus/isolation & purification, Streptococcus pneumoniae/isolation & purification	Phylogeny
Pathogenicity	17893163	In vitro ability of Staphylococcus aureus isolates from bacteraemic patients with and without metastatic complications to invade vascular endothelial cells.	Park WB, Kim SH, Kang CI, Cho JH, Bang JW, Park KW, Lee YS, Kim NJ, Oh MD, Kim HB, Won Choe K	J Med Microbiol	10.1099/jmm.0.46765-0	2007	Adult, Aged, Bacteremia/microbiology, Colony Count, Microbial, Community-Acquired Infections/microbiology, Cytoplasm/microbiology, Endothelial Cells/microbiology, Female, Humans, Male, Middle Aged, Staphylococcal Infections/microbiology, Staphylococcus aureus/isolation & purification/pathogenicity	Enzymology
Pathogenicity	17993505	Efficacy of telavancin in a murine model of pneumonia induced by methicillin-susceptible Staphylococcus aureus.	Hegde SS, Reyes N, Skinner R, Difuntorum S	J Antimicrob Chemother	10.1093/jac/dkm417	2007	Aminoglycosides/pharmacology/therapeutic use, Animals, Anti-Bacterial Agents/pharmacology/therapeutic use, Female, Lipoglycopeptides, Methicillin Resistance/drug effects, Mice, Mice, Inbred BALB C, Pneumonia, Staphylococcal/drug therapy/microbiology, Staphylococcus aureus/*drug effects/pathogenicity
Pathogenicity	18041123	[Influence of doxorubicin on the development of resistance of staphylococci to ceftriaxone].	Shapoval OG	Zh Mikrobiol Epidemiol Immunobiol		2007	Anti-Bacterial Agents/pharmacology, Antibiotics, Antineoplastic/pharmacology, Ceftriaxone/pharmacology, Doxorubicin/pharmacology, Drug Resistance, Bacterial/drug effects, Humans, Microbial Sensitivity Tests, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects
Pathogenicity	18177345	Effect of tumor necrosis factor-alpha on intracellular Staphylococcus aureus in vascular endothelial cells.	Park WB, Lee JH, Jeon JH, Lee SJ, Kim SH, Kim NJ, Kim HB, Oh MD, Choe KW	FEMS Immunol Med Microbiol	10.1111/j.1574-695X.2007.00365.x	2008	Anti-Bacterial Agents/pharmacology, Apoptosis, Cell Line, Colony Count, Microbial, Endothelial Cells/microbiology, Humans, L-Lactate Dehydrogenase/metabolism, Microbial Viability, Oxacillin/pharmacology, Staphylococcus aureus/drug effects, Tumor Necrosis Factor-alpha/*immunology	Enzymology
Pathogenicity	18332629	Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi.	Ryge TS, Frimodt-Moller N, Hansen PR	Chemotherapy	10.1159/000119707	2008	Anti-Infective Agents/chemistry/pharmacology, Bacteria/drug effects/isolation & purification, Drug Resistance, Microbial/physiology, Fungi/drug effects/isolation & purification/physiology, Humans, Lysine/chemistry/pharmacology, Microbial Sensitivity Tests/methods, Peptoids/chemistry/*pharmacology	Enzymology
Pathogenicity	18505206	Comparison of agar dilution and E-test for antimicrobial susceptibility testing of Campylobacter coil isolates recovered from 80 Ontario swine farms.	Varela NP, Friendship R, Dewey C, Valdivieso A	Can J Vet Res		2008	Agar, Animals, Anti-Bacterial Agents/pharmacology, Campylobacter coli/drug effects/growth & development, Colony Count, Microbial/instrumentation/methods/standards/veterinary, Drug Resistance, Bacterial, Microbial Sensitivity Tests/instrumentation/methods/standards/*veterinary, Ontario, Reproducibility of Results, Sensitivity and Specificity, Swine, Swine Diseases/drug therapy/microbiology
Pathogenicity	18614315	Newly defined in vitro quality control ranges for oritavancin broth microdilution testing and impact of variation in testing parameters.	Arhin FF, Tomfohrde K, Draghi DC, Aranza M, Parr TR Jr, Sahm DF, Moeck G	Diagn Microbiol Infect Dis	10.1016/j.diagmicrobio.2008.05.009	2008	Anti-Bacterial Agents/pharmacology, Enterococcus faecalis/drug effects, Glycopeptides/pharmacology, Humans, Lipoglycopeptides, Microbial Sensitivity Tests/methods/standards, Polysorbates, Quality Control, Reference Standards, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects
Pathogenicity	18715512	Antimicrobial activity of some sulfonamide derivatives on clinical isolates of Staphylococus aureus.	Genc Y, Ozkanca R, Bekdemir Y	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-7-17	2008	Anti-Bacterial Agents/pharmacology, Hospitals, Humans, Microbial Sensitivity Tests, Oxacillin/pharmacology, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects/isolation & purification, Sulfonamides/chemistry/pharmacology, Turkey	Enzymology
Pathogenicity	18818469	Antibacterial effects of three experimental quaternary ammonium salt (QAS) monomers on bacteria associated with oral infections.	Xiao YH, Chen JH, Fang M, Xing XD, Wang H, Wang YJ, Li F	J Oral Sci	10.2334/josnusd.50.323	2008	Anti-Bacterial Agents/chemistry/pharmacology, Bacteria, Anaerobic/drug effects, Colony Count, Microbial, Microbial Sensitivity Tests, Molecular Structure, Mouth Diseases/microbiology, Quaternary Ammonium Compounds/chemistry/*pharmacology, Staphylococcus aureus/drug effects
Pathogenicity	19104027	Oritavancin kills stationary-phase and biofilm Staphylococcus aureus cells in vitro.	Belley A, Neesham-Grenon E, McKay G, Arhin FF, Harris R, Beveridge T, Parr TR Jr, Moeck G	Antimicrob Agents Chemother	10.1128/AAC.00766-08	2008	Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Colony Count, Microbial, Dose-Response Relationship, Drug, Drug Resistance, Multiple, Bacterial/drug effects, Glycopeptides/pharmacology, Kinetics, Lipoglycopeptides, Methicillin/pharmacology/therapeutic use, Methicillin Resistance/drug effects, Microbial Sensitivity Tests, Plankton/drug effects, Staphylococcus aureus/drug effects/*growth & development/ultrastructure, Vancomycin/pharmacology/therapeutic use, Vancomycin Resistance/drug effects	Enzymology
Pathogenicity	19146534	In vitro anti-biofilm activity of Boswellia spp. oleogum resin essential oils.	Schillaci D, Arizza V, Dayton T, Camarda L, Di Stefano V	Lett Appl Microbiol	10.1111/j.1472-765X.2008.02469.x	2008	Bacterial Adhesion/drug effects, Biofilms/drug effects/growth & development, Boswellia/chemistry, Candida albicans/drug effects/growth & development, Growth Inhibitors/pharmacology, Microbial Sensitivity Tests, Microbial Viability, Oils, Volatile/pharmacology, Staining and Labeling, Staphylococcus aureus/drug effects/growth & development, Staphylococcus epidermidis/drug effects/growth & development, Tetrazolium Salts/metabolism, Thiazoles/metabolism	Metabolism
Pathogenicity	19226402	Investigation of functional and morphological changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Origanum compactum essential oil.	Bouhdid S, Abrini J, Zhiri A, Espuny MJ, Manresa A	J Appl Microbiol	10.1111/j.1365-2672.2008.04124.x	2009	Anti-Bacterial Agents/pharmacology, Cell Membrane Permeability/drug effects, Chlorhexidine/pharmacology, Membrane Potentials/drug effects, Microbial Sensitivity Tests, Microscopy, Electron, Transmission, Oils, Volatile/chemistry/pharmacology, Origanum/chemistry, Plant Oils/chemistry/pharmacology, Polymyxin B/pharmacology, Potassium/metabolism, Pseudomonas aeruginosa/cytology/drug effects/ultrastructure, Staphylococcus aureus/cytology/*drug effects/ultrastructure	Metabolism
Pathogenicity	19343338	Anti-adhesion activity of two biosurfactants produced by Bacillus spp. prevents biofilm formation of human bacterial pathogens.	Rivardo F, Turner RJ, Allegrone G, Ceri H, Martinotti MG	Appl Microbiol Biotechnol	10.1007/s00253-009-1987-7	2009	Bacillus/chemistry/metabolism, Bacteria/drug effects, Bacterial Adhesion/drug effects, Bacterial Infections/microbiology, Bacterial Physiological Phenomena/drug effects, Biofilms/drug effects, Humans, Surface-Active Agents/chemistry/metabolism/pharmacology	Metabolism
Pathogenicity	19544478	Synthesis, antibacterial and antifungal activities of novel 1,2,4-triazolium derivatives.	Luo Y, Lu YH, Gan LL, Zhou CH, Wu J, Geng RX, Zhang YY	Arch Pharm (Weinheim)	10.1002/ardp.200800221	2009	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Bacteria/drug effects, Fungi/drug effects, Mass Spectrometry, Microbial Sensitivity Tests, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Spectrophotometry, Infrared, Triazoles/chemical synthesis/chemistry/pharmacology
Pathogenicity	19548887	Antimicrobial and antistaphylococcal biofilm activity from the sea urchin Paracentrotus lividus.	Schillaci D, Arizza V, Parrinello N, Di Stefano V, Fanara S, Muccilli V, Cunsolo V, Haagensen JJ, Molin S	J Appl Microbiol	10.1111/j.1365-2672.2009.04394.x	2010	Animals, Anti-Infective Agents/chemistry/isolation & purification/pharmacology, Biofilms/drug effects, Cell Fractionation, Cytosol/chemistry, Microbial Sensitivity Tests, Microbial Viability/drug effects, Microscopy, Confocal, Paracentrotus/cytology/immunology/metabolism, Peptides/chemistry/pharmacology, Staining and Labeling, Staphylococcal Infections/prevention & control, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/*drug effects, Thymosin/chemistry/genetics	Enzymology
Enzymology	19583457	[Evaluation of rapid antimicrobial susceptibility test for Staphylococcus aureus by chemiluminescent assay and its application for screening of beta-lactam antibiotic induced vancomycin-resistant MRSA].	Nagasawa Z, Nakashima Y, Oho M, Kusaba K, Manome I, Nagayama A	Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi		2008	Luminescent Measurements, Methicillin-Resistant Staphylococcus aureus/drug effects/isolation & purification, Microbial Sensitivity Tests/methods, Teicoplanin/pharmacology, Vancomycin/pharmacology, Vancomycin Resistance, beta-Lactams/pharmacology	Phylogeny
Pathogenicity	19639538	Ceanothane and lupane type triterpenes from Zizyphus joazeiro - an anti-staphylococcal evaluation.	Leal IC, dos Santos KR, Junior II, Antunes OA, Porzel A, Wessjohann L, Kuster RM	Planta Med	10.1055/s-0029-1185947	2009	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Brazil, Medicine, Traditional, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Plant Extracts/pharmacology, Triterpenes/isolation & purification/pharmacology, Ziziphus/*chemistry	Enzymology
Cultivation	19688248	Comparative evaluation of a rapid MRSA detection assay based on multiplex real-time PCR versus MRSA screening cultures containing egg yolk.	Sumitani Y, Kobayashi Y	J Infect Chemother	10.1007/s10156-009-0685-9	2009	Bacterial Proteins/genetics, Cell Culture Techniques, Culture Media/chemistry, DNA Primers/genetics, Egg Yolk, Methicillin Resistance/genetics, Methicillin-Resistant Staphylococcus aureus/genetics/isolation & purification, Penicillin-Binding Proteins, Polymerase Chain Reaction/methods, Sensitivity and Specificity, Staphylococcal Infections/*diagnosis/microbiology, Transcription Factors/genetics	Enzymology
Pathogenicity	19699074	Synergism and postantibiotic effect of tobramycin and Melaleuca alternifolia (tea tree) oil against Staphylococcus aureus and Escherichia coli.	D'Arrigo M, Ginestra G, Mandalari G, Furneri PM, Bisignano G	Phytomedicine	10.1016/j.phymed.2009.07.008	2009	Anti-Bacterial Agents/pharmacology, Drug Resistance, Drug Synergism, Drug Therapy, Combination, Escherichia coli/drug effects, Melaleuca/chemistry, Microbial Sensitivity Tests, Plant Extracts/chemistry/pharmacology, Staphylococcus aureus/drug effects, Tea Tree Oil/pharmacology, Tobramycin/*pharmacology
Pathogenicity	19752277	Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700).	Locke JB, Hilgers M, Shaw KJ	Antimicrob Agents Chemother	10.1128/AAC.00871-09	2009	Acetamides/chemistry/pharmacology, Anti-Bacterial Agents/chemistry/pharmacology, Linezolid, Methicillin-Resistant Staphylococcus aureus/drug effects/genetics, Microbial Sensitivity Tests, Molecular Structure, Mutation, Oxazolidinones/chemistry/pharmacology, RNA, Ribosomal, 23S/genetics, Ribosomal Protein L3, Ribosomal Proteins/genetics, Staphylococcus aureus/drug effects/genetics, Tetrazoles/chemistry/pharmacology
Pathogenicity	19860905	Application of a high throughput Alamar blue biofilm susceptibility assay to Staphylococcus aureus biofilms.	Pettit RK, Weber CA, Pettit GR	Ann Clin Microbiol Antimicrob	10.1186/1476-0711-8-28	2009	Anti-Bacterial Agents/pharmacology, Biofilms/drug effects/growth & development, Humans, Microbial Sensitivity Tests/methods, Microbial Viability/drug effects, Oxazines/metabolism, Oxidation-Reduction, Reproducibility of Results, Staphylococcus aureus/drug effects/growth & development, Statistics as Topic, Tetrazolium Salts/metabolism, Xanthenes/metabolism	Metabolism
Enzymology	19933805	Lack of bactericidal antagonism or synergism in vitro between oxacillin and vancomycin against methicillin-susceptible strains of Staphylococcus aureus.	Joukhadar C, Pillai S, Wennersten C, Moellering RC Jr, Eliopoulos GM	Antimicrob Agents Chemother	10.1128/AAC.00348-09	2009	Anti-Bacterial Agents/pharmacokinetics/pharmacology, Drug Antagonism, Drug Synergism, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Oxacillin/pharmacokinetics/pharmacology, Vancomycin/pharmacokinetics/pharmacology	Pathogenicity
Pathogenicity	19942397	Relationship between structure and antibacterial activity of lipophilic N-acyldiamines.	de Almeida CG, Garbois GD, Amaral LM, Diniz CC, Le Hyaric M	Biomed Pharmacother	10.1016/j.biopha.2009.09.013	2009	Anti-Bacterial Agents/chemistry/pharmacology, Diamines/administration & dosage/chemistry/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Microbial Sensitivity Tests, Structure-Activity Relationship
Pathogenicity	19955747	Benzoxazine series of histidine kinase inhibitors as potential antimicrobial agents with activity against enterococci.	Mueller-Premru M, Zidar N, Spik VC, Krope A, Kikelj D	Chemotherapy	10.1159/000263228	2009	Anti-Bacterial Agents/pharmacology, Benzoxazines/pharmacology, Enterococcus/drug effects, Escherichia coli/drug effects, Histidine Kinase, Microbial Sensitivity Tests, Protein Kinase Inhibitors/pharmacology, Protein Kinases/drug effects/metabolism, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Vancomycin Resistance	Metabolism
Metabolism	20030722	Effect of the association of reduced glutathione and ciprofloxacin on the antimicrobial activity in Staphylococcus aureus.	Paez PL, Becerra MC, Albesa I	FEMS Microbiol Lett	10.1111/j.1574-6968.2009.01867.x	2009	Anti-Bacterial Agents/pharmacology, Chloramphenicol/pharmacology, Ciprofloxacin/pharmacology, Drug Interactions, Gentamicins/pharmacology, Glutathione/pharmacology, Microbial Sensitivity Tests, Reactive Oxygen Species/metabolism, Staphylococcus aureus/drug effects	Pathogenicity
Pathogenicity	20049525	In vitro activity of antimicrobial agents against Legionella isolated from environmental water systems: first results from Turkey.	Erdogan H, Can F, Demirbilek M, Timurkaynak F, Arslan H	Environ Monit Assess	10.1007/s10661-009-1293-y	2010	Anti-Infective Agents/pharmacology, Humans, Legionella pneumophila/drug effects, Legionnaires' Disease/microbiology, Microbial Sensitivity Tests, Turkey, Water Microbiology, Water Supply
Pathogenicity	20060624	Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4,6-pyrimidinediones.	Tomasic T, Zidar N, Mueller-Premru M, Kikelj D, Masic LP	Eur J Med Chem	10.1016/j.ejmech.2009.12.030	2009	Anti-Bacterial Agents/chemical synthesis/pharmacology, Bacteria/drug effects/growth & development, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Pyrimidines/chemical synthesis/pharmacology, Spectrometry, Mass, Electrospray Ionization, Spectrophotometry, Infrared, Thiazolidines/chemical synthesis/pharmacology
Pathogenicity	20084919	[Investigation of antibacterial activity of sertralin].	Coban AY, Tanriverdi Cayci Y, Keles Uludag S, Durupinar B	Mikrobiyol Bul		2009	Anti-Bacterial Agents/pharmacology, Antidepressive Agents/pharmacology, Bacteria/drug effects, Humans, Microbial Sensitivity Tests, Serotonin Uptake Inhibitors/pharmacology, Sertraline/*pharmacology
	20186866	Synthesis and in vitro antibacterial activity of 7-(3-alkoxyimino-4-methyl-4-methylaminopiperidin-1-yl)-fluoroquinolone derivatives.	Zhang YB, Feng LS, You XF, Guo Q, Guo HY, Liu ML	Arch Pharm (Weinheim)	10.1002/ardp.200900191	2010	Anti-Bacterial Agents/chemical synthesis/pharmacology, Chemistry, Pharmaceutical/methods, Ciprofloxacin/pharmacology, Fluoroquinolones/chemical synthesis/chemistry/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship
Pathogenicity	20226886	Biofilm formation on bone grafts and bone graft substitutes: comparison of different materials by a standard in vitro test and microcalorimetry.	Clauss M, Trampuz A, Borens O, Bohner M, Ilchmann T	Acta Biomater	10.1016/j.actbio.2010.03.011	2010	Bacterial Adhesion, Biofilms/growth & development, Bone Substitutes/analysis, Bone Transplantation, Calorimetry/methods, Colony Count, Microbial, Humans, Materials Testing/methods, Sonication, Staphylococcus aureus/cytology/physiology/ultrastructure, Staphylococcus epidermidis/cytology/*physiology/ultrastructure, Surface Properties
Pathogenicity	20428059	Synthesis and antimicrobial activity of novel Ag-N-hetero-cyclic carbene complexes.	Ozdemir I, Ozcan EO, Gunal S, Gurbuz N	Molecules	10.3390/molecules15042499	2010	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Candida albicans/drug effects, Candida tropicalis/drug effects, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Heterocyclic Compounds/chemical synthesis/chemistry/pharmacology, Imidazolidines/chemistry, Magnetic Resonance Spectroscopy, Methane/analogs & derivatives/chemistry, Nitrogen/chemistry, Pseudomonas aeruginosa/drug effects, Silver/chemistry, Staphylococcus aureus/drug effects
Pathogenicity	20456525	Functional and ultrastructural changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Cinnamomum verum essential oil.	Bouhdid S, Abrini J, Amensour M, Zhiri A, Espuny MJ, Manresa A	J Appl Microbiol	10.1111/j.1365-2672.2010.04740.x	2010	Anti-Bacterial Agents/pharmacology, Cell Membrane Permeability/drug effects, Cinnamomum/chemistry, Membrane Potentials/drug effects, Oils, Volatile/pharmacology, Potassium/metabolism, Pseudomonas aeruginosa/drug effects/metabolism/ultrastructure, Staphylococcus aureus/drug effects/metabolism/ultrastructure, Thiobarbiturates/analysis	Metabolism
Pathogenicity	20515462	Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation.	Petek M, Baebler S, Kuzman D, Rotter A, Podlesek Z, Gruden K, Ravnikar M, Urleb U	BMC Microbiol	10.1186/1471-2180-10-159	2010	Anti-Bacterial Agents/pharmacology, Biological Transport/drug effects, Cell Wall/metabolism, Coenzymes/biosynthesis, Dose-Response Relationship, Drug, Energy Metabolism/drug effects, Fosfomycin/pharmacology, Gene Expression Profiling, Nucleic Acids/biosynthesis, Oligonucleotide Array Sequence Analysis, Peptidoglycan/biosynthesis, Phosphoenolpyruvate/metabolism, Staphylococcus aureus/drug effects, Time Factors, Transcription, Genetic/*drug effects	Metabolism
Pathogenicity	20553344	Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6''-O-lauroyl ester.	Celiz G, Audisio MC, Daz M	J Appl Microbiol	10.1111/j.1365-2672.2010.04773.x	2010	Anti-Infective Agents/chemistry/pharmacology, Flavanones/chemistry/pharmacology, Flavones/chemistry/pharmacology, Glucosides/chemistry/pharmacology, Listeria monocytogenes/drug effects/ultrastructure, Phlorhizin/*analogs & derivatives/chemistry/pharmacology
Pathogenicity	20572203	MRT letter: Spatial distribution of vancomycin-induced damage in Staphylococcus epidermidis biofilm: an electron microscopic study.	Singh R, Ray P, Das A, Sharma M	Microsc Res Tech	10.1002/jemt.20871	2010	Amikacin/pharmacology, Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Ciprofloxacin/pharmacology, Humans, Microscopy, Electron, Scanning, Staphylococcus epidermidis/drug effects/ultrastructure, Vancomycin/*pharmacology
Pathogenicity	20582913	Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution.	Gonzalez R, Albericio F, Cascone O, Iannucci NB	J Pept Sci	10.1002/psc.1258	2010	Alanine/chemistry, Anti-Infective Agents/chemical synthesis/chemistry/pharmacology, Escherichia coli/drug effects, Hemolysis/drug effects, Humans, Microbial Sensitivity Tests, Muramidase/chemistry/pharmacology, Peptides/chemical synthesis/chemistry/*pharmacology, Staphylococcus aureus/drug effects, Structure-Activity Relationship
	20634934	Corneal deposit of ciprofloxacin after laser assisted subepithelial keratomileusis procedure: a case report.	De Benedetti G, Brancaccio A	J Ophthalmol	10.1155/2010/296034	2010
Pathogenicity	20648496	Multistep virtual screening for rapid and efficient identification of non-nucleoside bacterial thymidine kinase inhibitors.	Zander J, Hartenfeller M, Hahnke V, Proschak E, Besier S, Wichelhaus TA, Schneider G	Chemistry	10.1002/chem.201001347	2010	Amino Acid Sequence, Drug Design, High-Throughput Screening Assays/methods, Humans, Methicillin Resistance, Microbial Sensitivity Tests, Models, Molecular, Molecular Sequence Data, Molecular Structure, Sequence Alignment, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Thymidine Kinase/antagonists & inhibitors, Trimethoprim, Sulfamethoxazole Drug Combination/pharmacology/therapeutic use	Genetics
	20839321	Efficacy of moxifloxacin compared to teicoplanin in the treatment of implant-related chronic osteomyelitis in rats.	Ozturan KE, Yucel I, Kocoglu E, Cakici H, Guven M	J Orthop Res	10.1002/jor.21159	2010	Animals, Anti-Bacterial Agents/administration & dosage/therapeutic use, Aza Compounds/administration & dosage/therapeutic use, Chronic Disease, Disease Models, Animal, Fluoroquinolones, Injections, Intraperitoneal, Male, Moxifloxacin, Osteomyelitis/drug therapy/microbiology, Prosthesis-Related Infections/complications/drug therapy, Quinolines/administration & dosage/therapeutic use, Rats, Rats, Wistar, Staphylococcal Infections/complications/drug therapy, Staphylococcus aureus, Teicoplanin/administration & dosage/therapeutic use, Treatment Outcome
Pathogenicity	20880412	Diminished in vitro antibacterial activity of oxacillin against clinical isolates of borderline oxacillin-resistant Staphylococcus aureus.	Croes S, Beisser PS, Terporten PH, Neef C, Deurenberg RH, Stobberingh EE	Clin Microbiol Infect	10.1111/j.1469-0691.2010.02956.x	2010	Acetamides/pharmacology, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Daptomycin/pharmacology, Drug Resistance, Bacterial, Humans, Linezolid, Microbial Sensitivity Tests, Oxacillin/pharmacology, Oxazolidinones/pharmacology, Penicillin Resistance, Penicillin-Binding Proteins, Plasmids/genetics, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects/enzymology/genetics/isolation & purification, Vancomycin/pharmacology, beta-Lactamases/metabolism	Enzymology
Pathogenicity	20949909	Self-protecting bactericidal titanium alloy surface formed by covalent bonding of daptomycin bisphosphonates.	Chen CP, Wickstrom E	Bioconjug Chem	10.1021/bc100136e	2010	Alloys/chemistry, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Daptomycin/analogs & derivatives/chemistry/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Staphylococcus aureus/drug effects, Surface Properties, Titanium/*chemistry
Enzymology	20974887	Prevalence of Staphylococcus aureus and lack of its lytic bacteriophages in the anterior nares of patients and healthcare workers at a rural clinic.	Aswani VH, Shukla SK	Clin Med Res	10.3121/cmr.2010.954	2010	Adult, Aged, Bacteriophages/isolation & purification, Female, Health Personnel, Humans, Male, Methicillin-Resistant Staphylococcus aureus/growth & development/isolation & purification/virology, Middle Aged, Nose Diseases/epidemiology/microbiology, Prevalence, *Rural Health Services	Phylogeny
Pathogenicity	21251840	Synthesis of egonol derivatives and their antimicrobial activities.	Emirdag-Ozturk S, Karayildirim T, Anil H	Bioorg Med Chem	10.1016/j.bmc.2010.12.044	2010	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Bacillus subtilis/drug effects, Benzodioxoles/chemical synthesis/chemistry/pharmacology, Benzofurans/analysis/chemical synthesis, Candida albicans/drug effects, Escherichia coli/drug effects, Microbial Sensitivity Tests, Molecular Structure, Seeds, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Styrax, Sulfuric Acid Esters/chemical synthesis/chemistry/pharmacology
Metabolism	21255298	Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms.	Di Stefano A, D'Aurizio E, Trubiani O, Grande R, Di Campli E, Di Giulio M, Di Bartolomeo S, Sozio P, Iannitelli A, Nostro A, Cellini L	Microb Biotechnol	10.1111/j.1751-7915.2009.00120.x	2009	Bacterial Proteins/genetics, Biofilms, Elasticity, Hemolysis, Microscopy, Confocal, Staphylococcus aureus/chemistry/physiology, Staphylococcus epidermidis/chemistry/physiology, Trans-Activators/genetics, Viscoelastic Substances/metabolism, Viscosity
Pathogenicity	21326597	Proteome analyses of cellular proteins in methicillin-resistant Staphylococcus aureus treated with rhodomyrtone, a novel antibiotic candidate.	Sianglum W, Srimanote P, Wonglumsom W, Kittiniyom K, Voravuthikunchai SP	PLoS One	10.1371/journal.pone.0016628	2011	Anti-Bacterial Agents/pharmacology/therapeutic use, Bacterial Proteins/analysis/drug effects/metabolism, Drug Resistance, Bacterial/physiology, Drugs, Investigational/pharmacology/therapeutic use, Ethanol/chemistry/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects/metabolism, Microbial Sensitivity Tests, Microbial Viability/drug effects, Microscopy, Electron, Transmission, Plant Extracts/pharmacology/therapeutic use, Proteome/analysis/drug effects, Time Factors, Virulence Factors/analysis/metabolism, Xanthones/*pharmacology/therapeutic use	Metabolism
Pathogenicity	21393141	Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design.	Bhagunde P, Singh R, Ledesma KR, Chang KT, Nikolaou M, Tam VH	J Antimicrob Chemother	10.1093/jac/dkr054	2011	Anti-Bacterial Agents/pharmacology, Aza Compounds/pharmacology, Drug Resistance, Bacterial, Escherichia coli/drug effects, Fluoroquinolones/pharmacology, Humans, Levofloxacin, Microbial Sensitivity Tests, Microbial Viability/drug effects, Models, Biological, Models, Theoretical, Moxifloxacin, Mutation, Ofloxacin/pharmacology, Quinolines/pharmacology, Staphylococcus aureus/*drug effects, Time Factors
Pathogenicity	21406118	Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-beta-boswellic acid from Boswellia serrata.	Raja AF, Ali F, Khan IA, Shawl AS, Arora DS, Shah BA, Taneja SC	BMC Microbiol	10.1186/1471-2180-11-54	2011	Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Boswellia/chemistry, Microbial Sensitivity Tests, Resins, Plant/pharmacology, Staphylococcus aureus/drug effects, Triterpenes/*pharmacology
Pathogenicity	21609344	Norfloxacin and ursolic acid: in vitro association and postantibiotic effect against Staphylococcus aureus.	Filocamo A, Bisignano C, D'Arrigo M, Ginestra G, Mandalari G, Galati EM	Lett Appl Microbiol	10.1111/j.1472-765X.2011.03090.x	2011	Anti-Bacterial Agents/pharmacology, Drug Therapy, Combination, Humans, Methicillin Resistance/drug effects, Microbial Sensitivity Tests, Norfloxacin/pharmacology, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects/growth & development, Triterpenes/pharmacology
Pathogenicity	21630572	Antibiofilm activity of selected plant essential oils and their major components.	Budzynska A, Wieckowska-Szakiel M, Sadowska B, Kalemba D, Rozalska B	Pol J Microbiol		2011	Biofilms/drug effects, Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Oils, Volatile/pharmacology
Enzymology	21693461	Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.	Alt S, Mitchenall LA, Maxwell A, Heide L	J Antimicrob Chemother	10.1093/jac/dkr247	2011	Aminocoumarins/chemistry/pharmacology, Anti-Bacterial Agents/chemistry/pharmacology, Bacterial Proteins/biosynthesis/isolation & purification, Cloning, Molecular, DNA Gyrase/genetics, DNA Topoisomerase IV/antagonists & inhibitors/genetics, DNA, Superhelical/chemistry, Escherichia coli/drug effects/enzymology/genetics, Glutamates/pharmacology, Microbial Sensitivity Tests, Reverse Transcriptase Polymerase Chain Reaction, Sodium Glutamate/pharmacology, Staphylococcus aureus/drug effects/enzymology/genetics, Structure-Activity Relationship, Topoisomerase II Inhibitors, Topoisomerase Inhibitors/*pharmacology	Pathogenicity
	21702740	Mupirocin calcium microencapsulation via spray drying: feed solvent influence on microparticle properties, stability and antimicrobial activity.	Durrigl M, Kregar ML, Hafner A, Klaric MS, Filipovic-Grcic J	Drug Dev Ind Pharm	10.3109/03639045.2011.580350	2011	Analysis of Variance, Anti-Bacterial Agents/chemistry, Calorimetry, Differential Scanning, Delayed-Action Preparations/chemistry, Desiccation, Drug Compounding, Drug Stability, Mupirocin/chemistry, *Nebulizers and Vaporizers, Particle Size, Polymers, Solubility, Solvents, Spectroscopy, Fourier Transform Infrared, Thermogravimetry
Phylogeny	21892356	Pseudonocardians A-C, new diazaanthraquinone derivatives from a deap-sea actinomycete Pseudonocardia sp. SCSIO 01299.	Li S, Tian X, Niu S, Zhang W, Chen Y, Zhang H, Yang X, Zhang W, Li W, Zhang S, Ju J, Zhang C	Mar Drugs	10.3390/md9081428	2011	Actinomycetales/chemistry/genetics/isolation & purification, Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Benzoquinones/chemistry/isolation & purification/pharmacology, Cell Line, Tumor, China, Crystallography, X-Ray/methods, Geologic Sediments/microbiology, Humans, Magnetic Resonance Spectroscopy/methods, Mass Spectrometry/methods, Models, Molecular, Oceans and Seas, Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis/methods, Sequence Analysis, RNA/methods	Enzymology
Phylogeny	21897400	Lobophorins E and F, new spirotetronate antibiotics from a South China Sea-derived Streptomyces sp. SCSIO 01127.	Niu S, Li S, Chen Y, Tian X, Zhang H, Zhang G, Zhang W, Yang X, Zhang S, Ju J, Zhang C	J Antibiot (Tokyo)	10.1038/ja.2011.78	2011	Anti-Bacterial Agents/chemistry/metabolism/pharmacology, China, Cluster Analysis, DNA, Bacterial/chemistry/genetics, DNA, Ribosomal/chemistry/genetics, Enterococcus faecalis/drug effects, Geologic Sediments/microbiology, Inhibitory Concentration 50, Macrolides/chemistry/metabolism/pharmacology, Magnetic Resonance Spectroscopy, Mass Spectrometry, Microbial Sensitivity Tests, Models, Molecular, Molecular Sequence Data, Molecular Structure, Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Staphylococcus aureus/drug effects, Streptomyces/classification/genetics/isolation & purification/*metabolism	Metabolism
Enzymology	22011691	Antimicrobial effect of statins: organic solvents might falsify microbiological testing results.	Matzneller P, Manafi M, Zeitlinger M	Int J Clin Pharmacol Ther	10.5414/cp201581	2011	Anti-Infective Agents/pharmacology, Hydrogen-Ion Concentration, Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology, Methanol/pharmacology, Microbial Sensitivity Tests, Simvastatin/pharmacology, Solvents/pharmacology
Pathogenicity	22064531	Generic vancomycin enriches resistant subpopulations of Staphylococcus aureus after exposure in a neutropenic mouse thigh infection model.	Rodriguez CA, Agudelo M, Zuluaga AF, Vesga O	Antimicrob Agents Chemother	10.1128/AAC.05129-11	2011	Animals, Anti-Bacterial Agents/administration & dosage/adverse effects/pharmacokinetics, Colony Count, Microbial, Disease Models, Animal, Drug Administration Schedule, Drugs, Generic/administration & dosage/adverse effects/pharmacokinetics, Female, Humans, Methicillin Resistance/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects/growth & development, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Neutropenia/microbiology, Staphylococcal Infections/drug therapy/microbiology, Therapeutic Equivalency, Thigh/microbiology, Tissue Extracts, *Vancomycin/administration & dosage/adverse effects/pharmacokinetics	Enzymology
Pathogenicity	22129590	Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression.	Mitchell G, Lafrance M, Boulanger S, Seguin DL, Guay I, Gattuso M, Marsault E, Bouarab K, Malouin F	J Antimicrob Chemother	10.1093/jac/dkr510	2011	Aminoglycosides/pharmacology, Animals, Anti-Bacterial Agents/pharmacology, Culture Media/chemistry, Drug Resistance, Multiple, Bacterial/drug effects, Drug Synergism, Erythrocytes/microbiology, Gene Expression Profiling, Gene Expression Regulation, Bacterial/drug effects, Hemolysin Proteins/antagonists & inhibitors, Hemolysis, Horses, Microbial Sensitivity Tests, Microbial Viability/drug effects, Real-Time Polymerase Chain Reaction, Staphylococcus aureus/drug effects/pathogenicity, Time Factors, Tomatine/analogs & derivatives/pharmacology, Virulence, Virulence Factors/antagonists & inhibitors	Cultivation
Pathogenicity	22210435	Enhanced activity of linezolid against Staphylococcus aureus in cerebrospinal fluid.	Schwameis R, Fille M, Manafi M, Zeitlinger M, Sauermann R	Res Microbiol	10.1016/j.resmic.2011.12.004	2011	Acetamides/pharmacology, Anti-Bacterial Agents/pharmacology, Cerebrospinal Fluid/microbiology, Humans, Linezolid, Microbial Sensitivity Tests, Microbial Viability/drug effects, Oxazolidinones/pharmacology, Staphylococcus aureus/*drug effects, Staphylococcus epidermidis/drug effects
Metabolism	22336123	[Effects of Staphylococcus aureus supernatant on expression of various cytokines by neutrophils and retinal pigment epithelium cells].	Lou BS, Yuan ZH, Luo YW, Lin XF	Zhonghua Yan Ke Za Zhi		2011	Cells, Cultured, Coculture Techniques, Culture Media, Conditioned/toxicity, Humans, Interleukin-1beta/metabolism, Interleukin-6/metabolism, Neutrophils/cytology/drug effects/metabolism, Retinal Pigment Epithelium/cytology/drug effects/metabolism, Staphylococcus aureus, Tumor Necrosis Factor-alpha/metabolism	Pathogenicity
Pathogenicity	22349957	Ciprofloxacin-induced antibacterial activity is reversed by vitamin E and vitamin C.	Masadeh MM, Mhaidat NM, Alzoubi KH, Al-Azzam SI, Shaweesh AI	Curr Microbiol	10.1007/s00284-012-0094-7	2012	Anti-Bacterial Agents/antagonists & inhibitors/pharmacology, Ascorbic Acid/antagonists & inhibitors/pharmacology, Bacteria/drug effects/isolation & purification, Bacterial Infections/microbiology, Ciprofloxacin/antagonists & inhibitors/pharmacology, Drug Antagonism, Humans, Microbial Sensitivity Tests, Vitamin E/antagonists & inhibitors/pharmacology	Enzymology
Phenotype	22434711	Classifying compound mechanism of action for linking whole cell phenotypes to molecular targets.	Bourne CR, Wakeham N, Bunce RA, Nammalwar B, Berlin KD, Barrow WW	J Mol Recognit	10.1002/jmr.2174	2012	Anti-Bacterial Agents/analysis/classification/pharmacology, Cluster Analysis, Drug Evaluation, Preclinical/methods, Microarray Analysis, Microbial Sensitivity Tests/methods, Phenotype, Staphylococcus aureus/drug effects	Phylogeny
	22509721	In vitro analysis of bacterial morphology by atomic force microscopy of low level laser therapy 660, 830 and 904 nm.	de Sousa NT, Guirro RR, Santana HF, Silva CC	Photomed Laser Surg	10.1089/pho.2011.3160	2012	Colony Count, Microbial, Low-Level Light Therapy, Microscopy, Atomic Force, Radiation Dosage, Staphylococcus aureus/growth & development/radiation effects
Pathogenicity	22526313	Front-loaded linezolid regimens result in increased killing and suppression of the accessory gene regulator system of Staphylococcus aureus.	Tsuji BT, Brown T, Parasrampuria R, Brazeau DA, Forrest A, Kelchlin PA, Holden PN, Peloquin CA, Hanna D, Bulitta JB	Antimicrob Agents Chemother	10.1128/AAC.05453-11	2012	Acetamides/pharmacology, Linezolid, Methicillin-Resistant Staphylococcus aureus/drug effects/genetics, Microbial Sensitivity Tests, Monte Carlo Method, Oxazolidinones/pharmacology, Real-Time Polymerase Chain Reaction, Staphylococcus aureus/*drug effects/genetics
	22579134	A pilot study of a triple antimicrobial-bonded Dacron graft for the prevention of aortic graft infection.	Aboshady I, Raad I, Shah AS, Vela D, Dvorak T, Safi HJ, Buja LM, Khalil KG	J Vasc Surg	10.1016/j.jvs.2012.02.008	2012	Animals, Anti-Infective Agents/administration & dosage, Aorta, Abdominal/microbiology/pathology/surgery, Blood Vessel Prosthesis, Blood Vessel Prosthesis Implantation/adverse effects/instrumentation, Chlorhexidine/administration & dosage, Coated Materials, Biocompatible, Disease Models, Animal, Drug Therapy, Combination, Minocycline/administration & dosage, Pilot Projects, Polyethylene Terephthalates, Prosthesis Design, Prosthesis-Related Infections/microbiology/pathology/prevention & control, Rifampin/administration & dosage, Staphylococcal Infections/microbiology/pathology/prevention & control, Swine, Swine, Miniature, Time Factors
Pathogenicity	22684972	Comparison of microplate and macrodilution methods in time-kill study of new antimicrobial drugs.	Zhou Y, Hou Z, Fang C, Xue X, Da F, Wang Y, Bai H, Luo X	Folia Microbiol (Praha)	10.1007/s12223-012-0168-8	2012	Anti-Infective Agents/pharmacology, Escherichia coli/drug effects, Microbial Sensitivity Tests/methods, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects
Pathogenicity	22814462	Disk diffusion and MIC quality control ranges for BC-3205 and BC-3781, two novel pleuromutilin antibiotics.	Ross JE, Sader HS, Ivezic-Schoenfeld Z, Paukner S, Jones RN	J Clin Microbiol	10.1128/JCM.01294-12	2012	Anti-Bacterial Agents/pharmacology, Diterpenes/pharmacology, Haemophilus influenzae/drug effects, Humans, Microbial Sensitivity Tests/standards, Polycyclic Compounds, Quality Control, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects
Pathogenicity	22845330	Synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives.	Guzeldemirci NU, Satana D, Kucukbasmaci O	J Enzyme Inhib Med Chem	10.3109/14756366.2012.700926	2012	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Bacteria/drug effects, Dose-Response Relationship, Drug, Fungi/drug effects, Hydrazines/chemical synthesis/chemistry/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Structure-Activity Relationship, Thiadiazoles/chemical synthesis/chemistry/pharmacology, Thiourea/analogs & derivatives/chemical synthesis/chemistry/pharmacology, Triazoles/chemical synthesis/chemistry/pharmacology
Pathogenicity	23037005	Impact of pH on activity of trimethoprim, fosfomycin, amikacin, colistin and ertapenem in human urine.	Burian A, Erdogan Z, Jandrisits C, Zeitlinger M	Pharmacology	10.1159/000342423	2012	Amikacin/pharmacology, Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Colistin/pharmacology, Ertapenem, Fosfomycin/pharmacology, Humans, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Trimethoprim/pharmacology, Urine/*chemistry, beta-Lactams/pharmacology
Pathogenicity	23136829	Fluostatins I-K from the South China Sea-derived micromonospora rosaria SCSIO N160.	Zhang W, Liu Z, Li S, Lu Y, Chen Y, Zhang H, Zhang G, Zhu Y, Zhang G, Zhang W, Liu J, Zhang C	J Nat Prod	10.1021/np300505y	2012	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology, Bacillus subtilis/drug effects, Candida albicans/drug effects, Crystallography, X-Ray, Drug Screening Assays, Antitumor, Escherichia coli/drug effects, Female, Fluorenes/chemistry/isolation & purification/pharmacology, Geologic Sediments, Humans, Microbial Sensitivity Tests, Micromonospora/chemistry, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oceans and Seas, RNA, Ribosomal, 16S/genetics, Staphylococcus aureus/drug effects, Streptomyces/chemistry	Phylogeny
Pathogenicity	23229481	In vitro pharmacodynamics of AZD5206 against Staphylococcus aureus.	Tam VH, Chang KT, Yang Z, Newman J, Hu M	Antimicrob Agents Chemother	10.1128/AAC.01208-12	2012	Anti-Bacterial Agents/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Organic Chemicals/*pharmacology, Staphylococcal Infections/microbiology
Pathogenicity	23232977	Comparison of Rosco Neo-Sensitabs with Oxoid paper disks in EUCAST disk diffusion antimicrobial susceptibility testing on Mueller-Hinton agar.	Justesen US, Acar Z, Olsson K, Jensen TG, Kerrn MB, Skov RL, Gahrn-Hansen B	Eur J Clin Microbiol Infect Dis	10.1007/s10096-012-1785-5	2012	Agar, Anti-Infective Agents/pharmacology, Bacteria/drug effects, Bacterial Infections/microbiology, Culture Media, Disk Diffusion Antimicrobial Tests/instrumentation/methods/standards, Humans	Cultivation
Enzymology	23317050	A rabbit model of right-sided Staphylococcus aureus endocarditis created with echocardiographic guidance.	Wang ML, Zhang Y, Fan M, Guo YJ, Ren WD, Luo EJ	Cardiovasc Ultrasound	10.1186/1476-7120-11-3	2013	Animals, Cardiac Catheterization/adverse effects, Catheters/microbiology, Disease Models, Animal, Echocardiography/methods, Endocarditis, Bacterial/diagnostic imaging/etiology/microbiology, Female, Male, Rabbits, Staphylococcal Infections/diagnostic imaging/etiology/microbiology, Staphylococcus aureus/isolation & purification	Phylogeny
Pathogenicity	23361610	Biofilm formation by staphylococci on fresh, fresh-frozen and processed human and bovine bone grafts.	Clauss M, Tafin UF, Bizzini A, Trampuz A, Ilchmann T	Eur Cell Mater	10.22203/ecm.v025a11	2013	Aged, Animals, Bacterial Load, Biofilms, Bone Transplantation, Cattle, Cryopreservation, Femur Head/microbiology, Humans, Male, Sonication, Staphylococcus aureus/*physiology
Enzymology	23433441	Pharmacokinetics, pharmacodynamics and efficacy of novel FabI inhibitor AFN-1252 against MSSA and MRSA in the murine thigh infection model.	Banevicius MA, Kaplan N, Hafkin B, Nicolau DP	J Chemother	10.1179/1973947812Y.0000000061	2013	Acetamides/pharmacology, Animals, Anti-Bacterial Agents/pharmacokinetics/pharmacology, Benzofurans/pharmacokinetics/pharmacology, Community-Acquired Infections/drug therapy/metabolism/microbiology, Female, Linezolid, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Oxazolidinones/pharmacology, Pyrones/pharmacokinetics/pharmacology, Staphylococcal Infections/drug therapy/*metabolism/microbiology, Staphylococcus aureus/drug effects, Thigh/microbiology	Metabolism
	23493936	In vitro determination of the antibiotic susceptibility of biofilm-forming Pseudomonas aeruginosa and Staphylococcus aureus: possible role of proteolytic activity and membrane lipopolysaccharide.	Masadeh MM, Mhaidat NM, Alzoubi KH, Hussein EI, Al-Trad EI	Infect Drug Resist	10.2147/IDR.S41501	2013
Pathogenicity	23547139	Dissecting the mechanisms of linezolid resistance in a Drosophila melanogaster infection model of Staphylococcus aureus.	Diaz L, Kontoyiannis DP, Panesso D, Albert ND, Singh KV, Tran TT, Munita JM, Murray BE, Arias CA	J Infect Dis	10.1093/infdis/jit138	2013	Acetamides/pharmacology, Animals, Anti-Bacterial Agents/pharmacology, Disease Models, Animal, Dose-Response Relationship, Drug, Drosophila melanogaster/drug effects/microbiology, Drug Resistance, Bacterial, Female, Linezolid, Mice, Mice, Inbred ICR, Oxazolidinones/pharmacology, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects
Pathogenicity	23558199	Effects of Zataria multiflora Boiss. essential oil on growth and gene expression of enterotoxins A, C and E in Staphylococcus aureus ATCC 29213.	Azizkhani M, Misaghi A, Basti AA, Gandomi H, Hosseini H	Int J Food Microbiol	10.1016/j.ijfoodmicro.2013.02.020	2013	Enterotoxins/genetics, Gene Expression Regulation, Bacterial/drug effects, Lamiaceae/chemistry, Microbial Sensitivity Tests, Oils, Volatile/chemistry/pharmacology, Staphylococcus aureus/*drug effects
Pathogenicity	23619231	Antimicrobial/anti-biofilm activity of expired blood platelets and their released products.	Rozalski MI, Micota B, Sadowska B, Paszkiewicz M, Wieckowska-Szakiel M, Rozalska B	Postepy Hig Med Dosw (Online)	10.5604/17322693.1046009	2013	Acetamides/pharmacology, Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Biofilms, Blood Platelets/immunology, Endocarditis, Bacterial/drug therapy/immunology/microbiology, Humans, Linezolid, Microbial Sensitivity Tests, Oxacillin/pharmacology, Oxazolidinones/pharmacology, Staphylococcal Infections/drug therapy/immunology/microbiology, Staphylococcus/drug effects, Staphylococcus aureus/drug effects, Vancomycin/pharmacology, beta-Thromboglobulin/*immunology
Pathogenicity	23632681	Effects of selenium coating of orthopaedic implant surfaces on bacterial adherence and osteoblastic cell growth.	Holinka J, Pilz M, Kubista B, Presterl E, Windhager R	Bone Joint J	10.1302/0301-620X.95B5.31216	2013	Anti-Bacterial Agents/pharmacology, Bacterial Adhesion/drug effects, Cell Line, Tumor, Cell Proliferation/drug effects, Coated Materials, Biocompatible, Humans, Materials Testing, Prostheses and Implants/microbiology, Selenium/pharmacology, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/*drug effects, Surface Properties, Titanium
Pathogenicity	23647672	Antimicrobial activity of newly synthesized methylsulfanyl-triazoloquinazoline derivatives.	Al-Salahi R, Marzouk M, Awad G, Al-Omar M, Ezzeldin E	J Pharm Pharmacol	10.1111/jphp.12039	2013	Anti-Bacterial Agents/chemistry/pharmacology, Antifungal Agents/chemistry/pharmacology, Fungi/drug effects, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Mesylates/chemistry/pharmacology, Microbial Sensitivity Tests, Quinazolines/chemistry/pharmacology
Enzymology	23670623	New antibacterial germacrene from Verbesina negrensis.	Mora FD, Alpan L, de Tommasi N, McCracken VJ, Nieto M	Planta Med	10.1055/s-0032-1328542	2013	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Enterococcus faecalis/drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Sesquiterpenes, Germacrane/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects, Verbesina/*chemistry	Phylogeny
	23757948	Comparative study on the antibacterial activity of some flavonoids and their sulfonic derivatives.	Woznicka E, Kuzniar A, Nowak D, Nykiel E, Kopacz M, Gruszecka J, Golec K	Acta Pol Pharm		2013	Anti-Bacterial Agents/chemistry/pharmacology, Flavonoids/chemistry/pharmacology, Quercetin/analogs & derivatives/pharmacology, Structure-Activity Relationship, Sulfonic Acids/pharmacology
Enzymology	23771045	Antibacterial and cytotoxic new napyradiomycins from the marine-derived Streptomyces sp. SCSIO 10428.	Wu Z, Li S, Li J, Chen Y, Saurav K, Zhang Q, Zhang H, Zhang W, Zhang W, Zhang S, Zhang C	Mar Drugs	10.3390/md11062113	2013	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology, Bacteria/drug effects, Cell Line, Tumor, Drug Screening Assays, Antitumor, Humans, Inhibitory Concentration 50, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Naphthoquinones/chemistry/isolation & purification/pharmacology, Neoplasms/drug therapy/pathology, Streptomyces/chemistry	Phylogeny
Metabolism	23856775	Differential adaptive responses of Staphylococcus aureus to in vitro selection with different antimicrobial peptides.	Shireen T, Singh M, Das T, Mukhopadhyay K	Antimicrob Agents Chemother	10.1128/AAC.00780-13	2013	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Antimicrobial Cationic Peptides, Cell Membrane/drug effects/metabolism, Gramicidin, Microbial Sensitivity Tests, Peptides/pharmacology, Phospholipids/metabolism, Staphylococcus aureus/drug effects/metabolism	Pathogenicity
Pathogenicity	23951794	Comparison of chlorine dioxide and dichloroisocyanurate disinfectants for use in the dental setting.	Patel M, Ebonwu J, Cutler E	SADJ		2012	Anti-Infective Agents/pharmacology, Bacillus subtilis/drug effects, Candida albicans/drug effects, Chlorine/pharmacology, Chlorine Compounds/pharmacology, Dental Disinfectants/pharmacology, Hepatitis B virus/drug effects, Humans, Materials Testing, Mycobacterium avium/drug effects, Mycobacterium tuberculosis/drug effects, Oxides/pharmacology, Pseudomonas aeruginosa/drug effects, Spores, Bacterial/drug effects, Staphylococcus aureus/drug effects, Streptococcus mutans/drug effects, Time Factors, Triazines/pharmacology
Enzymology	23999155	Bioactive polyketides and alkaloids from Penicillium citrinum, a fungal endophyte isolated from Ocimum tenuiflorum.	Lai D, Brotz-Oesterhelt H, Muller WEG, Wray V, Proksch P	Fitoterapia	10.1016/j.fitote.2013.08.017	2013	Alkaloids/chemistry/isolation & purification/pharmacology, Animals, Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology/therapeutic use, Biological Products/chemistry/pharmacology/therapeutic use, Cell Line, Tumor, Endophytes/chemistry, Inhibitory Concentration 50, Lymphoma/drug therapy, Mice, Molecular Structure, Ocimum/microbiology, Penicillium/chemistry, Polyketides/chemistry/isolation & purification/pharmacology/therapeutic use, Staphylococcus aureus/*drug effects	Phylogeny
Enzymology	24054287	Detection and enumeration of Staphylococcus aureus from bovine milk samples by real-time polymerase chain reaction.	Botaro BG, Cortinhas CS, Marco LV, Moreno JFG, Silva LFP, Benites NR, Santos MV	J Dairy Sci	10.3168/jds.2013-6559	2013	Animals, Anti-Infective Agents, Cattle/microbiology, Female, Mastitis, Bovine/microbiology, Micrococcal Nuclease/genetics, Milk/microbiology, Propylene Glycols, Real-Time Polymerase Chain Reaction/methods/veterinary, Reproducibility of Results, Sensitivity and Specificity, Staphylococcal Infections/microbiology/veterinary, Staphylococcus aureus/enzymology/genetics/isolation & purification	Phylogeny
Pathogenicity	24055630	Probiotic properties of lactobacilli species isolated from children's feces.	Tulumoglu S, Yuksekdag ZN, Beyatli Y, Simsek O, Cinar B, Yasar E	Anaerobe	10.1016/j.anaerobe.2013.09.006	2013	Adolescent, Anti-Bacterial Agents/pharmacology, Antibiosis, Bacterial Adhesion, Bile Acids and Salts/toxicity, Child, Child, Preschool, Cholesterol/metabolism, Escherichia coli/growth & development, Feces/microbiology, Female, Humans, Hydrogen-Ion Concentration, Lactobacillus/drug effects/isolation & purification/physiology, Male, Microbial Sensitivity Tests, Microbial Viability/drug effects, Polysaccharides, Bacterial/metabolism, Probiotics/isolation & purification, Pseudomonas aeruginosa/growth & development, Staphylococcus aureus/growth & development	Metabolism
Pathogenicity	24076183	Synthesis, crystal structures, and anti-drug-resistant Staphylococcus aureus activities of novel 4-hydroxycoumarin derivatives.	Li MK, Li J, Liu BH, Zhou Y, Li X, Xue XY, Hou Z, Luo XX	Eur J Pharmacol	10.1016/j.ejphar.2013.09.040	2013	4-Hydroxycoumarins/chemical synthesis/chemistry/pharmacology, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Chemistry Techniques, Synthetic, Crystallography, X-Ray, Drug Resistance, Bacterial/drug effects, Microbial Sensitivity Tests, Models, Molecular, Molecular Conformation, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Time Factors
Pathogenicity	24097361	Antibacterial effects of curcumin: An in vitro minimum inhibitory concentration study.	Gunes H, Gulen D, Mutlu R, Gumus A, Tas T, Topkaya AE	Toxicol Ind Health	10.1177/0748233713498458	2013	Anti-Bacterial Agents/pharmacology, Bacillus subtilis/drug effects, Curcumin/pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects
Pathogenicity	24171975	In vitro evaluation of the minimum bactericidal concentrations of different root-end filling materials.	Kocak MM, Kocak S, Oktay EA, Kilic A, Yaman SD	J Contemp Dent Pract	10.5005/jp-journals-10024-1330	2013	Aerobiosis, Aluminum Compounds/pharmacology, Anti-Bacterial Agents/administration & dosage/pharmacology, Bacterial Load/drug effects, Bacteriological Techniques, Bismuth/pharmacology, Calcium Compounds/pharmacology, Dental Cements/pharmacology, Drug Combinations, Enterococcus faecalis/drug effects, Gram-Positive Bacteria/drug effects, Humans, Materials Testing, Methylmethacrylates/pharmacology, Microbial Sensitivity Tests, Oxides/pharmacology, Root Canal Filling Materials/*pharmacology, Silicates/pharmacology, Staphylococcus aureus/drug effects, Streptococcus mutans/drug effects, Temperature, Time Factors, Zinc Oxide-Eugenol Cement/pharmacology
Pathogenicity	24251399	Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406.	Song Y, Huang H, Chen Y, Ding J, Zhang Y, Sun A, Zhang W, Ju J	J Nat Prod	10.1021/np4006025	2013	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, China, Drug Screening Assays, Antitumor, Female, Hep G2 Cells, Humans, MCF-7 Cells, Magnetic Resonance Spectroscopy, Methicillin Resistance/drug effects, Microbial Sensitivity Tests, Molecular Structure, Naphthoquinones/chemistry/isolation & purification/pharmacology, Oceans and Seas, Phenazines/chemistry/isolation & purification/pharmacology, Sesquiterpenes/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Streptomyces/*chemistry	Enzymology
Pathogenicity	24333580	Synthesis and evaluation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-(4-substitutedpiperazin-1-yl)ace tyl)piperazin-1-yl)quinoline-3-carboxylic acid derivatives as anti-tubercular and antibacterial agents.	Suresh N, Nagesh HN, Renuka J, Rajput V, Sharma R, Khan IA, Kondapalli Venkata Gowri CS	Eur J Med Chem	10.1016/j.ejmech.2013.10.055	2013	Anti-Bacterial Agents/chemistry/pharmacology, Carboxylic Acids/chemistry/pharmacology, Escherichia coli/drug effects, Escherichia coli Infections/drug therapy, Halogenation, Humans, Mycobacterium tuberculosis/drug effects, Quinolines/chemistry/pharmacology, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Tuberculosis/drug therapy
Pathogenicity	24378967	Synthesis of novel 2-(substituted amino)alkylthiopyrimidin-4(3H)-ones as potential antimicrobial agents.	Attia MI, El-Emam AA, Al-Turkistani AA, Kansoh AL, El-Brollosy NR	Molecules	10.3390/molecules19010279	2013	Anti-Infective Agents/chemical synthesis/chemistry/pharmacology, Bacteria/drug effects, Candida albicans/drug effects, Fungi/drug effects, Microbial Sensitivity Tests, Pyrimidines/chemical synthesis/chemistry/pharmacology, Staphylococcus aureus/drug effects
	24426114	Essential oils and herbal extracts as antimicrobial agents in cosmetic emulsion.	Herman A, Herman AP, Domagalska BW, Mlynarczyk A	Indian J Microbiol	10.1007/s12088-012-0329-0	2012
Enzymology	24614373	Pharmacodynamics of cefquinome in a neutropenic mouse thigh model of Staphylococcus aureus infection.	Wang J, Shan Q, Ding H, Liang C, Zeng Z	Antimicrob Agents Chemother	10.1128/AAC.01666-13	2014	Animals, Anti-Bacterial Agents/pharmacokinetics, Area Under Curve, Cephalosporins/pharmacokinetics, Disease Models, Animal, Female, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Neutropenia, Specific Pathogen-Free Organisms, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Tandem Mass Spectrometry, Thigh/microbiology	Proteome
	24640147	[Comparison of antibacterial activities of Tobramycin inhalation solutions].	Pisarev VV	Antibiot Khimioter		2013	Administration, Inhalation, Anti-Bacterial Agents/pharmacology, Dose-Response Relationship, Drug, Escherichia coli/growth & development, Microbial Sensitivity Tests/methods, Pseudomonas aeruginosa/growth & development, Staphylococcus aureus/growth & development, Tobramycin/*pharmacology
Pathogenicity	24676969	Extracorporeal shockwave increases the effectiveness of systemic antibiotic treatment in implant-related chronic osteomyelitis: experimental study in a rat model.	Inanmaz ME, Uslu M, Isik C, Kaya E, Tas T, Bayram R	J Orthop Res	10.1002/jor.22604	2014	Animals, Anti-Bacterial Agents/administration & dosage, High-Energy Shock Waves/therapeutic use, Models, Animal, Osteomyelitis/drug therapy, Prostheses and Implants/adverse effects, Rats, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects, Teicoplanin/administration & dosage, Tibia/microbiology
Enzymology	24721233	Selection and characterisation of Staphylococcus aureus mutants with reduced susceptibility to the investigational oxazolidinone MRX-I.	Huang Y, Xu Y, Liu S, Wang H, Xu X, Guo Q, Wu B, Gordeev MF, Wang W, Yuan Z, Wang M	Int J Antimicrob Agents	10.1016/j.ijantimicag.2014.02.008	2014	Anti-Bacterial Agents/pharmacology, Drug Resistance, Bacterial, Microbial Sensitivity Tests, Mutation, Mutation Rate, Oxazolidinones/pharmacology, Pyridones/pharmacology, RNA, Ribosomal, 23S/genetics, Ribosomal Proteins/genetics, Selection, Genetic, Serial Passage, Staphylococcus aureus/drug effects/isolation & purification	Phylogeny
Pathogenicity	24744220	Development of EUCAST zone diameter breakpoints and quality control range for Staphylococcus aureus with ceftaroline 5-mug disk.	Koeth LM, Matuschek E, Kahlmeter G, Alm RA, Ambler JE	Eur J Clin Microbiol Infect Dis	10.1007/s10096-014-2089-8	2014	Anti-Bacterial Agents/pharmacology, Cephalosporins/pharmacology, Humans, Microbial Sensitivity Tests/standards, Quality Control, Staphylococcus aureus/*drug effects
Pathogenicity	24748178	Negative-pressure wound therapy enhances local inflammatory responses in acute infected soft-tissue wound.	Liu D, Zhang L, Li T, Wang G, Du H, Hou H, Han L, Tang P	Cell Biochem Biophys	10.1007/s12013-014-9953-0	2014	Animals, Bacterial Load, Cell Count, Cytokines/genetics, Female, Gene Expression Regulation, Inflammation/genetics/immunology/therapy, Negative-Pressure Wound Therapy, Neutrophils/cytology, Rabbits, Soft Tissue Infections/genetics/immunology/therapy, Staphylococcal Infections/genetics/immunology/therapy, Staphylococcus aureus/physiology, Wound Infection/genetics/immunology/therapy
Pathogenicity	24757836	[A study of the single nucleotide polymorphism fragments of the AUR gene metalloprotease strains of Staphylococcus aureus isolated from the skin of patients with atopic dermatitis].	Tuyrin YA, Shamsutdinov AF, Fassahov RS	Mol Gen Mikrobiol Virusol		2014	Adolescent, Adult, Amino Acid Sequence, Bacterial Proteins/genetics, Child, Child, Preschool, Dermatitis, Atopic/microbiology, Female, Humans, Infant, Male, Metalloendopeptidases/genetics, Molecular Sequence Data, Polymorphism, Single Nucleotide, Skin/microbiology, Staphylococcus aureus/genetics/isolation & purification	Genetics
Pathogenicity	24794452	In vitro evaluation of antimicrobial features of sugammadex.	Hanci V, Vural A, Hanci SY, Ali Kiraz H, Omur D, Unver A	Braz J Anesthesiol	10.1016/j.bjane.2013.09.003	2013	Anti-Infective Agents/pharmacology, Bacteria/drug effects, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Sugammadex, gamma-Cyclodextrins/pharmacology
Enzymology	24844761	Sensitive and selective near-infrared fluorescent off-on probe and its application to imaging different levels of beta-lactamase in Staphylococcus aureus.	Li L, Li Z, Shi W, Li X, Ma H	Anal Chem	10.1021/ac501288e	2014	Fluorescent Dyes, Magnetic Resonance Spectroscopy, Spectrometry, Mass, Electrospray Ionization, Spectroscopy, Near-Infrared/methods, Staphylococcus aureus/enzymology, beta-Lactamases/metabolism	Metabolism
Pathogenicity	24905974	Effect of subinhibitory concentrations of chlorogenic acid on reducing the virulence factor production by Staphylococcus aureus.	Li G, Qiao M, Guo Y, Wang X, Xu Y, Xia X	Foodborne Pathog Dis	10.1089/fpd.2013.1731	2014	Anti-Bacterial Agents/pharmacology, Bacterial Adhesion/drug effects, Bacterial Toxins/genetics, Chlorogenic Acid/pharmacology, Coagulase/genetics, Enterotoxins/genetics, Fibrinogen/drug effects, Hemolysin Proteins/genetics, Hemolysis/drug effects, Humans, Microbial Sensitivity Tests, Staphylococcal Food Poisoning/microbiology/prevention & control, Staphylococcal Infections/microbiology/prevention & control, Staphylococcus aureus/drug effects/pathogenicity/physiology, Virulence Factors/genetics/*metabolism	Biotechnology
Pathogenicity	24920777	Quality control MIC ranges used for telavancin with application of a revised CLSI reference broth microdilution method.	Ross JE, Mendes RE, Jones RN	J Clin Microbiol	10.1128/JCM.01210-14	2014	Aminoglycosides/pharmacology, Anti-Bacterial Agents/pharmacology, Enterococcus faecalis/drug effects, Humans, Lipoglycopeptides, Microbial Sensitivity Tests/methods/standards, Quality Control, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/*drug effects
Pathogenicity	24947818	Synthesis, antibacterial activities, and theoretical studies of dicoumarols.	Li J, Hou Z, Chen GH, Li F, Zhou Y, Xue XY, Li ZP, Jia M, Zhang ZD, Li MK, Luo XX	Org Biomol Chem	10.1039/c4ob00772g	2014	Anti-Bacterial Agents/chemical synthesis/pharmacology/toxicity, Cell Death, Crystallography, X-Ray, Dicumarol/chemical synthesis/chemistry/pharmacology/toxicity, Electrons, Human Umbilical Vein Endothelial Cells/cytology/drug effects, Hydrogen Bonding, Methicillin-Resistant Staphylococcus aureus/drug effects/growth & development, Microbial Sensitivity Tests, *Models, Molecular, Quantum Theory, Static Electricity, Thermodynamics
	24950856	Right atrial pressure alterations during echocardiography-guided-catheterization predict tricuspid valvular impairment: a novel method for the creation of a rabbit model of Staphylococcus aureus endocarditis.	Wang ML, Zhang Y, Fan M, Guo YJ, Ren WD, Luo EJ	Cardiovasc Ultrasound	10.1186/1476-7120-12-21	2014	Animals, Atrial Function, Right/physiology, Atrial Pressure/physiology, Cardiac Catheterization/methods, Disease Models, Animal, Echocardiography/methods, Endocarditis, Bacterial/diagnostic imaging/microbiology, Female, Male, Predictive Value of Tests, Rabbits, Staphylococcal Infections/diagnostic imaging, Staphylococcus aureus, Tricuspid Valve/diagnostic imaging/microbiology, Tricuspid Valve Insufficiency/*diagnostic imaging
Pathogenicity	24980636	Antimicrobial, insecticidal and phytotoxic activities of Cotinus coggyria Scop. essential oil (Anacardiaceae).	Ulukanli Z, Karaborklu S, Bozok F, Cenet M, Ozturk B, Balcilar M	Nat Prod Res	10.1080/14786419.2014.928879	2014	Acyclic Monoterpenes, Anacardiaceae/chemistry, Animals, Anti-Infective Agents/chemistry/isolation & purification/pharmacology, Bicyclic Monoterpenes, Candida albicans/drug effects, Cyclohexenes/analysis, Dose-Response Relationship, Drug, Insecticides/pharmacology, Limonene, Microbial Sensitivity Tests, Monoterpenes/analysis, Oils, Volatile/analysis/*pharmacology, Plant Leaves/chemistry, Staphylococcus aureus/drug effects, Terpenes/analysis, Tribolium/drug effects	Enzymology
Pathogenicity	25036054	Influence of physico-chemical material characteristics on staphylococcal biofilm formation--a qualitative and quantitative in vitro analysis of five different calcium phosphate bone grafts.	Clauss M, Furustrand Tafin U, Betrisey B, van Garderen N, Trampuz A, Ilchmann T, Bohner M	Eur Cell Mater	10.22203/ecm.v028a04	2014	Biofilms/drug effects, Bone Transplantation, Calcium Phosphates/chemistry/pharmacology, Porosity, Staphylococcus aureus/drug effects/physiology, Staphylococcus epidermidis/drug effects/physiology, Tissue Scaffolds/chemistry/microbiology, Transplants/chemistry/*microbiology
Pathogenicity	25068263	Recombinant scorpine produced using SUMO fusion partner in Escherichia coli has the activities against clinically isolated bacteria and inhibits the Plasmodium falciparum parasitemia in vitro.	Zhang C, He X, Gu Y, Zhou H, Cao J, Gao Q	PLoS One	10.1371/journal.pone.0103456	2014	Acinetobacter baumannii/drug effects, Animals, Anti-Bacterial Agents/isolation & purification/metabolism/pharmacology, Antiprotozoal Agents/isolation & purification/metabolism/pharmacology, Bacteria/drug effects, Blotting, Western, Escherichia coli/genetics, Humans, Microbial Sensitivity Tests, Parasitemia/parasitology/prevention & control, Parasitic Sensitivity Tests, Plasmodium falciparum/drug effects, Recombinant Fusion Proteins/isolation & purification/metabolism/pharmacology, Scorpions/genetics/metabolism, Small Ubiquitin-Related Modifier Proteins/genetics/metabolism, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects	Metabolism
	25135015	The effects of oral antibiotics on infection prophylaxis in traumatic wounds.	Erbil B, Ersoy G, Ozkutuk A, Akarca FK, Korkmaz T, Demir OF, Kiyan S	Ulus Travma Acil Cerrahi Derg	10.5505/tjtes.2014.63993	2014	Administration, Oral, Animals, Anti-Bacterial Agents/administration & dosage/therapeutic use, Antibiotic Prophylaxis/methods, Rats, Rats, Wistar, Wound Infection/drug therapy/epidemiology
Pathogenicity	25136008	Identification and characterization of linezolid-resistant cfr-positive Staphylococcus aureus USA300 isolates from a New York City medical center.	Locke JB, Zuill DE, Scharn CR, Deane J, Sahm DF, Goering RV, Jenkins SG, Shaw KJ	Antimicrob Agents Chemother	10.1128/AAC.03380-14	2014	Acetamides/pharmacology, Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics, Clindamycin/pharmacology, Diterpenes/pharmacology, Drug Resistance, Multiple, Bacterial/genetics, Gene Transfer Techniques, Humans, Linezolid, Methicillin-Resistant Staphylococcus aureus/drug effects/genetics/isolation & purification, Microbial Sensitivity Tests, Molecular Sequence Data, New York, Organophosphates/pharmacology, Oxazoles/pharmacology, Oxazolidinones/pharmacology, Plasmids/genetics, Staphylococcal Infections/drug therapy/microbiology, Thiamphenicol/analogs & derivatives/pharmacology	Genetics
Enzymology	25145204	Pathogen removal during wastewater treatment by vermifiltration.	Arora S, Rajpal A, Kumar T, Bhargava R, Kazmi AA	Environ Technol	10.1080/09593330.2014.911358	2014	Animals, Biological Oxygen Demand Analysis, Enterobacteriaceae/isolation & purification/physiology, Filtration/methods, Hydrogen-Ion Concentration, Microbial Interactions, Oligochaeta, Waste Water/microbiology, Water Purification/*methods	Phylogeny
Pathogenicity	25148109	Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen.	Speck S, Courtiol A, Junkes C, Dathe M, Muller K, Schulze M	PLoS One	10.1371/journal.pone.0105949	2014	Animals, Antimicrobial Cationic Peptides/chemical synthesis/pharmacology, Drug Therapy, Combination, Gentamicins/pharmacology, Male, Microbial Sensitivity Tests, Semen/drug effects/microbiology, Semen Preservation/*methods, Swine
Pathogenicity	25151581	Cobalt(II) complexes with the antimicrobial drug enrofloxacin: structure, antimicrobial activity, DNA- and albumin-binding.	Protogeraki C, Andreadou EG, Perdih F, Turel I, Pantazaki AA, Psomas G	Eur J Med Chem	10.1016/j.ejmech.2014.08.043	2014	Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Bacillus/drug effects, Cattle, Cobalt/chemistry, DNA/drug effects, Dose-Response Relationship, Drug, Escherichia coli/drug effects, Microbial Sensitivity Tests, Molecular Structure, Organometallic Compounds/chemical synthesis/chemistry/pharmacology, Plasmids/drug effects, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Xanthomonas campestris/drug effects
Pathogenicity	25155597	Linezolid-resistant Staphylococcus aureus strain 1128105, the first known clinical isolate possessing the cfr multidrug resistance gene.	Locke JB, Zuill DE, Scharn CR, Deane J, Sahm DF, Denys GA, Goering RV, Shaw KJ	Antimicrob Agents Chemother	10.1128/AAC.03493-14	2014	Acetamides/therapeutic use, Adult, Anti-Bacterial Agents/therapeutic use, Bacterial Proteins/genetics, Base Sequence, Ceftazidime/therapeutic use, Cystic Fibrosis, DNA, Bacterial/genetics, Drug Resistance, Multiple, Bacterial/genetics, Female, Genes, MDR/genetics, Humans, Linezolid, Methicillin-Resistant Staphylococcus aureus/drug effects/genetics/isolation & purification, Microbial Sensitivity Tests, Molecular Sequence Data, Multilocus Sequence Typing, Oxazolidinones/therapeutic use, Plasmids/genetics, Pseudomonas Infections/drug therapy/microbiology, Pseudomonas aeruginosa/drug effects/isolation & purification, RNA, Ribosomal, 23S/genetics, Retrospective Studies, Sequence Analysis, DNA, Staphylococcal Infections/drug therapy/microbiology, Tobramycin/therapeutic use	Enzymology
Pathogenicity	25225069	Synergistic interaction of PMAP-36 and PRW4 with aminoglycoside antibiotics and their antibacterial mechanism.	Wang Z, Zhang L, Wang J, Wei D, Shi B, Shan A	World J Microbiol Biotechnol	10.1007/s11274-014-1739-4	2014	Aminoglycosides/pharmacology, Anti-Bacterial Agents/pharmacology, Antimicrobial Cationic Peptides/pharmacology, DNA, Bacterial/metabolism, Drug Synergism, Electrophoretic Mobility Shift Assay, Escherichia coli/drug effects, Microscopy, Confocal, Protein Binding, Proteins/pharmacology, Staphylococcus aureus/*drug effects	Metabolism
Enzymology	25268323	Selection of potential probiotic Enterococcus faecium isolated from Portuguese fermented food.	Barbosa J, Borges S, Teixeira P	Int J Food Microbiol	10.1016/j.ijfoodmicro.2014.09.009	2014	Animals, Antibiosis/physiology, Bacterial Physiological Phenomena, Enterococcus faecium/genetics/isolation & purification/physiology, Fermentation, Hot Temperature, Meat Products/microbiology, Microbial Viability, Milk/microbiology, Portugal, Probiotics/*isolation & purification	Phylogeny
	25312171	Phytochemical and biological activities of Bituminaria bituminosa L. (Fabaceae).	Azzouzi S, Zaabat N, Medjroubi K, Akkal S, Benlabed K, Smati F, Dijoux-Franca MG	Asian Pac J Trop Med	10.1016/S1995-7645(14)60278-9	2014
Enzymology	25371574	Antibacterial and anti-biofilm activity of flavonoids and triterpenes isolated from the extracts of Ficus sansibarica Warb. subsp. sansibarica (Moraceae) extracts.	Awolola GV, Koorbanally NA, Chenia H, Shode FO, Baijnath H	Afr J Tradit Complement Altern Med	10.4314/ajtcam.v11i3.19	2014	Anti-Bacterial Agents/analysis/isolation & purification/pharmacology, Biofilms/drug effects, Escherichia coli/drug effects/physiology, Ficus/chemistry, Flavonoids/analysis/isolation & purification/pharmacology, Microbial Sensitivity Tests, Plant Extracts/pharmacology, Plant Leaves/chemistry, Staphylococcus aureus/drug effects/physiology, Triterpenes/analysis/isolation & purification/pharmacology	Phylogeny
Pathogenicity	25424036	Testing the mutant selection window hypothesis in vitro and in vivo with Staphylococcus aureus exposed to fosfomycin.	Mei Q, Ye Y, Zhu YL, Cheng J, Chang X, Liu YY, Li HR, Li JB	Eur J Clin Microbiol Infect Dis	10.1007/s10096-014-2285-6	2014	Animals, Anti-Bacterial Agents/pharmacology, Drug Resistance, Bacterial, Female, Fosfomycin/pharmacology, Microbial Viability/drug effects, Mutation, Rabbits, Selection, Genetic, Staphylococcus aureus/drug effects
Pathogenicity	25428071	New type of protective hybrid and nanocomposite hybrid coatings containing silver and copper with an excellent antibacterial effect especially against MRSA.	Slamborova I, Zajicova V, Karpiskova J, Exnar P, Stibor I	Mater Sci Eng C Mater Biol Appl	10.1016/j.msec.2012.08.039	2012	Acinetobacter baumannii/drug effects/radiation effects, Anti-Bacterial Agents/chemistry/pharmacology, Coated Materials, Biocompatible/chemistry/pharmacology, Copper/chemistry, Light, Methicillin-Resistant Staphylococcus aureus/drug effects/radiation effects, Methylmethacrylate/chemistry, Nanocomposites/chemistry, Organometallic Compounds/chemistry, Proteus vulgaris/drug effects/radiation effects, Pseudomonas aeruginosa/drug effects/radiation effects, Silanes/chemistry, Silver/*chemistry, Ultraviolet Rays
Pathogenicity	25460310	New biscoumarin derivatives: synthesis, crystal structure, theoretical study and antibacterial activity against Staphylococcus aureus.	Qu D, Li J, Yang XH, Zhang ZD, Luo XX, Li MK, Li X	Molecules	10.3390/molecules191219868	2014	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Coumarins/chemical synthesis/chemistry/pharmacology, Crystallography, X-Ray, Microbial Sensitivity Tests, Models, Molecular, Quantum Theory, Staphylococcus aureus/drug effects/growth & development, Thermodynamics
Pathogenicity	25474870	[Effect of cinnamon and lavender oils on FtsZ gene expression in the Staphylococus aureus ATCC 29213].	Herman A, Bochenek J, Herman AP	Prikl Biokhim Mikrobiol		2013	Bacterial Proteins/biosynthesis, Cytoskeletal Proteins/biosynthesis, Gene Expression Regulation, Bacterial/drug effects, Lavandula, Oils, Volatile/pharmacology, Plant Oils/pharmacology, Staphylococcus aureus/metabolism	Metabolism
Pathogenicity	25556550	Synthesis and pharmacological evaluations of 4-hydroxycoumarin derivatives as a new class of anti-Staphylococcus aureus agents.	Li ZP, Li J, Qu D, Hou Z, Yang XH, Zhang ZD, Wang YK, Luo XX, Li MK	J Pharm Pharmacol	10.1111/jphp.12343	2014	4-Hydroxycoumarins/biosynthesis/pharmacology/therapeutic use, Animals, Anti-Bacterial Agents/pharmacology/therapeutic use, Human Umbilical Vein Endothelial Cells, Lung/drug effects/microbiology/pathology, Lung Diseases/drug therapy/microbiology/pathology, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Microbial Sensitivity Tests, Molecular Structure, Staphylococcal Infections/drug therapy/microbiology, Staphylococcus aureus
Pathogenicity	25613850	Anti-virulence potential of eugenyl acetate against pathogenic bacteria of medical importance.	Musthafa KS, Voravuthikunchai SP	Antonie Van Leeuwenhoek	10.1007/s10482-014-0364-4	2015	Acetates/pharmacology, Anti-Bacterial Agents/pharmacology, Eugenol/analogs & derivatives/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Pigments, Biological, Syzygium/chemistry, Virulence Factors/*antagonists & inhibitors
	25692135	In vitro bactericidal activity of 4- and 5-chloro-2-hydroxy-N-[1-oxo-1-(phenylamino)alkan-2-yl]benzamides against MRSA.	Zadrazilova I, Pospisilova S, Pauk K, Imramovsky A, Vinsova J, Cizek A, Jampilek J	Biomed Res Int	10.1155/2015/349534	2015	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Benzamides/chemical synthesis/chemistry/pharmacology, Methicillin-Resistant Staphylococcus aureus/*growth & development
Pathogenicity	25697605	Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.	Vandal J, Abou-Zaid MM, Ferroni G, Leduc LG	Pharm Biol	10.3109/13880209.2014.942867	2015	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Antifungal Agents/pharmacology, Bacteria/drug effects, Biological Products/pharmacology, Chromatography, High Pressure Liquid, Fungi/drug effects, Indicators and Reagents, Microbial Sensitivity Tests, Ontario, Oxazines, Plant Extracts/pharmacology, Plants/*chemistry, Xanthenes
Pathogenicity	25818154	Preparation of gentamicin dioctyl sulfosuccinate loaded poly(trimethylene carbonate) matrices intended for the treatment of orthopaedic infections.	ter Boo GA, Grijpma DW, Richards RG, Moriarty TF, Eglin D	Clin Hemorheol Microcirc	10.3233/CH-151935	2015	Anti-Bacterial Agents/administration & dosage/pharmacology, Biocompatible Materials/chemical synthesis/chemistry, Cell Line, Cell Survival, Dioctyl Sulfosuccinic Acid/chemistry, Dioxanes/chemistry, Drug Implants, Fibroblasts/drug effects/physiology, Gentamicins/administration & dosage/pharmacology, Humans, Microbial Sensitivity Tests, Polymers/chemistry, Prostheses and Implants, Staphylococcus/*drug effects, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects
Phylogeny	25820813	Bacillus subtilis subsp. subtilis CBMDC3f with antimicrobial activity against Gram-positive foodborne pathogenic bacteria: UV-MALDI-TOF MS analysis of its bioactive compounds.	Torres MJ, Petroselli G, Daz M, Erra-Balsells R, Audisio MC	World J Microbiol Biotechnol	10.1007/s11274-015-1847-9	2015	Anti-Bacterial Agents/analysis, Antibiosis, Bacillus subtilis/classification/isolation & purification/metabolism/physiology, Biological Products/analysis, Cluster Analysis, DNA Gyrase/genetics, DNA, Bacterial/chemistry/genetics, DNA, Ribosomal/chemistry/genetics, Food Microbiology, Gram-Positive Bacteria/growth & development/isolation & purification, Molecular Sequence Data, Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Spectrophotometry, Ultraviolet	Enzymology
Phylogeny	25922338	Development of a novel matrix-assisted laser desorption/ionization time-of-flight mass spectrum (MALDI-TOF-MS)-based typing method to identify meticillin-resistant Staphylococcus aureus clones.	Ueda O, Tanaka S, Nagasawa Z, Hanaki H, Shobuike T, Miyamoto H	J Hosp Infect	10.1016/j.jhin.2014.11.025	2015	Bacterial Typing Techniques/methods, DNA, Bacterial/analysis, Genetic Variation, Methicillin-Resistant Staphylococcus aureus/classification/genetics, Mutant Proteins/analysis, Reproducibility of Results, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Cultivation	26002505	Microbial fuel cell-based diagnostic platform to reveal antibacterial effect of beta-lactam antibiotics.	Schneider G, Czeller M, Rostas V, Kovacs T	Enzyme Microb Technol	10.1016/j.enzmictec.2015.04.004	2015	Anti-Bacterial Agents/pharmacology, Bioelectric Energy Sources, Biosensing Techniques, Culture Media, Disk Diffusion Antimicrobial Tests, Electrodes, Equipment Design, Escherichia coli/drug effects, Microbial Sensitivity Tests/methods, Miniaturization, Phenotype, Staphylococcus aureus/drug effects, beta-Lactams/pharmacology	Pathogenicity
Pathogenicity	26028441	Synergy between baicalein and penicillins against penicillinase-producing Staphylococcus aureus.	Qian M, Tang S, Wu C, Wang Y, He T, Chen T, Xiao X	Int J Med Microbiol	10.1016/j.ijmm.2015.05.001	2015	Animals, Anti-Bacterial Agents/pharmacology, Drug Synergism, Enzyme Inhibitors/pharmacology, Flavanones/pharmacology, Humans, Methicillin Resistance, Microbial Sensitivity Tests, Penicillinase/metabolism, Penicillins/pharmacology, Staphylococcus aureus/*drug effects/enzymology	Metabolism
Pathogenicity	26077886	Synthesis of biscoumarin and dihydropyran derivatives as two novel classes of potential anti-bacterial derivatives.	Li J, Xue XY, Li X, Hou Z, Yang XH, Qu D, Zhou Y, Zhang ZD, Luo XX, Li JT, Li MK	Arch Pharm Res	10.1007/s12272-015-0614-7	2015	Anti-Bacterial Agents/chemical synthesis/classification/pharmacology, Coumarins/chemical synthesis/classification/pharmacology, Crystallography, X-Ray/methods, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects/physiology, Microbial Sensitivity Tests/methods	Phylogeny
Pathogenicity	26079401	Salicylanilide carbamates: Promising antibacterial agents with high in vitro activity against methicillin-resistant Staphylococcus aureus (MRSA).	Zadrazilova I, Pospisilova S, Masarikova M, Imramovsky A, Ferriz JM, Vinsova J, Cizek A, Jampilek J	Eur J Pharm Sci	10.1016/j.ejps.2015.06.009	2015	Anti-Bacterial Agents/pharmacology, Cell Line, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Salicylanilides/*pharmacology
Pathogenicity	26162029	Synthesis, antitumor and antimicrobial activity of some new 6-methyl-3-phenyl-4(3H)-quinazolinone analogues: in silico studies.	Alanazi AM, Abdel-Aziz AA, Shawer TZ, Ayyad RR, Al-Obaid AM, Al-Agamy MH, Maarouf AR, El-Azab AS	J Enzyme Inhib Med Chem	10.3109/14756366.2015.1060482	2015	Anti-Infective Agents/chemical synthesis/pharmacology, Antineoplastic Agents/chemical synthesis/pharmacology, Cell Line, Tumor, Cell Proliferation, Cell Survival/drug effects, Humans, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, Quinazolinones/chemical synthesis/*pharmacology, Staphylococcaceae/drug effects
Pathogenicity	26213381	Potency and penetration of telavancin in staphylococcal biofilms.	Kirker KR, Fisher ST, James GA	Int J Antimicrob Agents	10.1016/j.ijantimicag.2015.05.022	2015	Aminoglycosides/pharmacology, Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Humans, Lipoglycopeptides, Staphylococcus aureus/drug effects/physiology, Staphylococcus epidermidis/*drug effects/physiology
Pathogenicity	26310860	Anti-biofilm activity of ultrashort cinnamic acid peptide derivatives against medical device-related pathogens.	Laverty G, McCloskey AP, Gorman SP, Gilmore BF	J Pept Sci	10.1002/psc.2805	2015	Anti-Bacterial Agents/adverse effects/chemistry/pharmacology, Biocompatible Materials, Biofilms/drug effects, Cell Line, Cell Survival/drug effects, Cinnamates/chemistry, Hemolysis/drug effects, Humans, Microbial Sensitivity Tests, Peptides/adverse effects/chemistry/pharmacology, Staphylococcus aureus/drug effects
	26372110	Antibacterial, antifungal and antimycobacterial activities of some pyrazoline, hydrazone and chalcone derivatives.	Evranos-Aksoz B, Onurdag FK, Ozgacar SO	Z Naturforsch C J Biosci	10.1515/znc-2014-4195	2015
Pathogenicity	26393571	Synthesis of Biscoumarin and Dihydropyran Derivatives and Evaluation of Their Antibacterial Activity.	Li J, Lv CW, Li XJ, Qu D, Hou Z, Jia M, Luo XX, Li X, Li MK	Molecules	10.3390/molecules200917469	2015	Anti-Bacterial Agents/chemical synthesis/pharmacology, Coumarins/chemical synthesis/pharmacology, Crystallography, X-Ray, Hydrogen Bonding, Methicillin-Resistant Staphylococcus aureus/drug effects, Molecular Structure, Pyrans/chemical synthesis/*pharmacology, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects
Genetics	26404610	Draft Genome Sequence of Methicillin-Sensitive Staphylococcus aureus ATCC 29213.	Soni I, Chakrapani H, Chopra S	Genome Announc	10.1128/genomeA.01095-15	2015
Pathogenicity	26468500	Standardization of Operator-Dependent Variables Affecting Precision and Accuracy of the Disk Diffusion Method for Antibiotic Susceptibility Testing.	Hombach M, Maurer FP, Pfiffner T, Bottger EC, Furrer R	J Clin Microbiol	10.1128/JCM.02351-15	2015	Anti-Bacterial Agents/pharmacology, Bacteria/drug effects, Colony Count, Microbial/standards, Densitometry/standards, Disk Diffusion Antimicrobial Tests/standards, Escherichia coli/drug effects, Specimen Handling/methods, Staphylococcus aureus/drug effects
Pathogenicity	26522947	Synthesis of biscoumarin and dihydropyran derivatives with promising antitumor and antibacterial activities.	Li J, Sui YP, Xin JJ, Du XL, Li JT, Huo HR, Ma H, Wang WH, Zhou HY, Zhan HD, Wang ZJ, Li C, Sui F, Li X	Bioorg Med Chem Lett	10.1016/j.bmcl.2015.10.063	2015	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antineoplastic Agents/chemical synthesis/chemistry/pharmacology, Apoptosis/drug effects, Carboplatin/chemical synthesis/chemistry/pharmacology, Cell Line, Tumor, Cell Proliferation/drug effects, Coumarins/chemical synthesis/chemistry/pharmacology, Crystallography, X-Ray, Humans, Inhibitory Concentration 50, Microbial Sensitivity Tests, Models, Molecular, Pyrans/chemical synthesis/chemistry/pharmacology, Staphylococcus aureus/drug effects
	26604928	In Vitro Evaluation of Antimicrobial Efficacy of Extracts Obtained from Raw and Fermented Wild Macrofungus, Lenzites quercina.	Ogidi OC, Oyetayo VO, Akinyele BJ	Int J Microbiol	10.1155/2015/106308	2015
	26626182	Prevention of perioperative vascular prosthetic infection with a novel triple antimicrobial-bonded arterial graft.	Aboshady I, Raad I, Vela D, Hassan M, Aboshady Y, Safi HJ, Buja LM, Khalil KG	J Vasc Surg	10.1016/j.jvs.2015.09.061	2015	Animals, Anti-Infective Agents/administration & dosage, Aorta, Abdominal/microbiology/pathology/surgery, Blood Vessel Prosthesis/adverse effects, Blood Vessel Prosthesis Implantation/adverse effects/instrumentation, Chlorhexidine/administration & dosage, Coated Materials, Biocompatible, Disease Models, Animal, Minocycline/administration & dosage, Polyethylene Terephthalates, Prosthesis Design, Prosthesis-Related Infections/diagnosis/microbiology/prevention & control, Rifampin/administration & dosage, Staphylococcal Infections/diagnosis/microbiology/*prevention & control, Swine, Swine, Miniature, Time Factors
Pathogenicity	26666773	Multi-functional Liposomes Enhancing Target and Antibacterial Immunity for Antimicrobial and Anti-Biofilm Against Methicillin-Resistant Staphylococcus aureus.	Meng Y, Hou X, Lei J, Chen M, Cong S, Zhang Y, Ding W, Li G, Li X	Pharm Res	10.1007/s11095-015-1825-9	2015	Animals, Anti-Bacterial Agents/immunology/pharmacology, Biofilms/drug effects, Clarithromycin/immunology/pharmacology, Kidney/microbiology, Liposomes/immunology, Macrophages/drug effects/immunology, Methicillin-Resistant Staphylococcus aureus/drug effects/immunology, Mice, Microbial Sensitivity Tests/methods, Phagocytosis/drug effects/immunology, Spleen/microbiology, Tissue Distribution/physiology, Wheat Germ Agglutinins/immunology
Pathogenicity	26747522	Enhanced anti-cancer and antimicrobial activities of curcumin nanoparticles.	Adahoun MA, Al-Akhras MH, Jaafar MS, Bououdina M	Artif Cells Nanomed Biotechnol	10.3109/21691401.2015.1129628	2016	Anti-Infective Agents/chemistry/pharmacology, Antineoplastic Agents/chemistry/pharmacology, Bacteria/growth & development, Cell Line, Curcumin/chemistry/pharmacology, HEK293 Cells, Humans, Male, Nanoparticles/chemistry, Prostatic Neoplasms/drug therapy
Pathogenicity	26751436	Antibacterial Properties of Tebipenem Pivoxil Tablet, a New Oral Carbapenem Preparation against a Variety of Pathogenic Bacteria in Vitro and in Vivo.	Yao Q, Wang J, Cui T, Yang Z, Su M, Zhao P, Yan H, Zhan Y, Yang H	Molecules	10.3390/molecules21010062	2016	Animals, Anti-Bacterial Agents/pharmacology, Carbapenems/pharmacology, Escherichia coli/drug effects/growth & development, Escherichia coli Infections/drug therapy/mortality/pathology, Female, Klebsiella Infections/drug therapy/mortality/pathology, Klebsiella pneumoniae/drug effects/growth & development, Male, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Pseudomonas Infections/drug therapy/mortality/pathology, Pseudomonas aeruginosa/drug effects/growth & development, Sepsis/drug therapy/microbiology/mortality/pathology, Staphylococcal Infections/*drug therapy/mortality/pathology, Staphylococcus aureus/drug effects/growth & development, Survival Analysis, Tablets
	26788319	Phenolic compounds, antioxidant, and antibacterial properties of pomace extracts from four Virginia-grown grape varieties.	Xu Y, Burton S, Kim C, Sismour E	Food Sci Nutr	10.1002/fsn3.264	2015
Metabolism	26833442	Evaluation of Antibacterial Activity and Reactive Species Generation of N-Benzenesulfonyl Derivatives of Heterocycles.	Martinez SR, Miana GE, Albesa I, Mazzieri MR, Becerra MC	Chem Pharm Bull (Tokyo)	10.1248/cpb.c15-00682	2016	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Benzene Derivatives/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Escherichia coli/drug effects/metabolism, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/metabolism, Quinolines/chemical synthesis/chemistry/pharmacology, Reactive Oxygen Species/metabolism, Staphylococcus aureus/drug effects/metabolism, Structure-Activity Relationship	Pathogenicity
Pathogenicity	26883392	Antimicrobial potency of single and combined mupirocin and monoterpenes, thymol, menthol and 1,8-cineole against Staphylococcus aureus planktonic and biofilm growth.	Kifer D, Muzinic V, Klaric MS	J Antibiot (Tokyo)	10.1038/ja.2016.10	2016	Anti-Bacterial Agents/administration & dosage/pharmacology, Biofilms/drug effects, Cyclohexanols/administration & dosage/pharmacology, Drug Synergism, Eucalyptol, Menthol/administration & dosage/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Monoterpenes/administration & dosage/pharmacology, Mupirocin/administration & dosage/pharmacology, Plankton/drug effects, Staphylococcus aureus/drug effects, Thymol/administration & dosage/pharmacology
Pathogenicity	26929622	Development of nanoantibiotic delivery system using cockle shell-derived aragonite nanoparticles for treatment of osteomyelitis.	Saidykhan L, Abu Bakar MZ, Rukayadi Y, Kura AU, Latifah SY	Int J Nanomedicine	10.2147/IJN.S95885	2016	Animal Shells/chemistry, Animals, Anti-Bacterial Agents/chemistry/pharmacology, Calcium Carbonate/chemistry, Cardiidae/chemistry, Cells, Cultured, Chemistry, Pharmaceutical, Drug Carriers, Drug Delivery Systems, Fetus/drug effects, Humans, Microbial Sensitivity Tests, Nanoparticles/administration & dosage/chemistry, Osteoblasts/cytology/drug effects, Osteomyelitis/drug therapy/pathology, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus/drug effects, Vancomycin/chemistry/*pharmacology, X-Ray Diffraction
	26998253	Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity.	Grace JL, Huang JX, Cheah SE, Truong NP, Cooper MA, Li J, Davis TP, Quinn JF, Velkov T, Whittaker MR	RSC Adv	10.1039/C5RA24361K	2016
Pathogenicity	27137748	Enhanced nanocurcumin toxicity against (PC3) tumor and microbial by using magnetic field in vitro.	Aldahoun MA, Jaafar MS, Al-Akhras MH, Bououdina M	Artif Cells Nanomed Biotechnol	10.1080/21691401.2016.1178137	2016	Anti-Bacterial Agents/chemistry/metabolism/pharmacokinetics/pharmacology, Antineoplastic Agents/chemistry/metabolism/pharmacokinetics/pharmacology, Bacteria/drug effects, Biological Availability, Biological Transport, Cell Line, Tumor, Cell Membrane Permeability, Curcumin/chemistry/metabolism/pharmacokinetics/pharmacology, Erythrocytes/drug effects, Humans, Magnetic Fields, Male, Nanoparticles/chemistry, Prostatic Neoplasms/pathology	Enzymology
Pathogenicity	27141642	[Influence of Chlorhexidine and Prontosan on Dual Species and Monospecies Biofilms Formed by Staphylococcus aureus and Pseudomonas aeruginosa].	Kuznetsova MV, Encheva YA, Samartsev VA	Antibiot Khimioter		2015	Anti-Infective Agents, Local/administration & dosage/pharmacology, Betaine, Biguanides/pharmacology, Biofilms/drug effects/growth & development, Chlorhexidine/administration & dosage/analogs & derivatives/pharmacology, Microscopy, Atomic Force, Pseudomonas aeruginosa/drug effects/growth & development, Staphylococcus aureus/drug effects/growth & development
Metabolism	27166532	Studies on bioactivity and secondary metabolites of crude extracts of Bidens pilosa L. (Asteraceae): A medicinal plant used in the Transkei region of South Africa.	Njume C, Gqaza BM, Rozani C, Goduka NI	Pak J Pharm Sci		2016	Anti-Bacterial Agents/isolation & purification/metabolism/pharmacology, Bacteria/drug effects/growth & development, Bidens/metabolism, Chemical Fractionation, Disk Diffusion Antimicrobial Tests, Drugs, Chinese Herbal/isolation & purification/metabolism/*pharmacology, Molecular Structure, Phytotherapy, Plants, Medicinal, Solvents/chemistry, South Africa	Enzymology
Pathogenicity	27183717	[ABILITY OF STAPHYLOCOCCUS OF VARIOUS STRAINS TO CREATE BIOFILMS AND THEIR EFFECT ON HUMAN BODY CELLS].	Kornienko MA, Kopyltsov VN, Shevlyagina NV, Didenko LV, Lyubasovskaya LA, Priputnevich TV, Ilina EN	Mol Gen Mikrobiol Virusol		2016	Biofilms/growth & development, Cell Line, Tumor, Humans, Staphylococcus/physiology
Enzymology	27239017	In vivo bactericidal efficacy of farnesol on Ti6Al4V implants.	Constantino JA, Delgado-Rastrollo M, Pacha-Olivenza MA, Perez-Giraldo C, Quiles M, Gonzalez-Martin ML, Gallardo-Moreno AM	Rev Esp Cir Ortop Traumatol	10.1016/j.recot.2016.04.004	2016	Alloys, Animals, Anti-Bacterial Agents/administration & dosage/therapeutic use, Bone Nails/adverse effects/microbiology, Colony Count, Microbial, Farnesol/administration & dosage/therapeutic use, Femur/microbiology/surgery, Male, Prosthesis-Related Infections/diagnosis/prevention & control, Random Allocation, Rats, Rats, Wistar, Staphylococcal Infections/diagnosis/etiology/prevention & control, Staphylococcus aureus/isolation & purification, *Titanium	Phylogeny
Pathogenicity	27498831	Antimicrobial evaluation of selected naturally occurring oxyprenylated secondary metabolites.	Di Giulio M, Genovese S, Fiorito S, Epifano F, Nostro A, Cellini L	Nat Prod Res	10.1080/14786419.2015.1079908	2015	1-Propanol/chemistry/pharmacology, Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/chemistry/pharmacology, Biofilms/drug effects, Candida albicans/drug effects, Drug Evaluation, Preclinical/methods, Escherichia coli/drug effects, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/physiology, *Secondary Metabolism, Staphylococcus aureus/drug effects/physiology, Staphylococcus epidermidis/drug effects/physiology, Terpenes/chemistry/pharmacology	Metabolism
	27681720	The Structure-Antimicrobial Activity Relationships of a Promising Class of the Compounds Containing the N-Arylpiperazine Scaffold.	Malik I, Csollei J, Jampilek J, Stanzel L, Zadrazilova I, Hosek J, Pospisilova S, Cizek A, Coffey A, O'Mahony J	Molecules	10.3390/molecules21101274	2016
Transcriptome	27739497	Comparative virulence studies and transcriptome analysis of Staphylococcus aureus strains isolated from animals.	Iqbal Z, Seleem MN, Hussain HI, Huang L, Hao H, Yuan Z	Sci Rep	10.1038/srep35442	2016	Animals, Bacterial Proteins/genetics/metabolism, Cell Line, Chickens, Female, Methicillin-Resistant Staphylococcus aureus/genetics/isolation & purification/pathogenicity, Mice, Mice, Inbred BALB C, Poultry Diseases/microbiology, Protein Kinases/genetics/metabolism, Staphylococcal Infections/microbiology/veterinary, Swine, Swine Diseases/microbiology, Trans-Activators/genetics/metabolism, *Transcriptome, Virulence/genetics	Metabolism
Proteome	27821440	Bacterial Replication Rate Modulation in Combination with Antimicrobial Therapy: Turning the Microbe against Itself.	Ambrose PG, VanScoy B, Conde H, McCauley J, Rubino CM, Bhavnani SM	Antimicrob Agents Chemother	10.1128/AAC.01605-16	2016	Anti-Infective Agents/pharmacology, Chromatography, Liquid, Levofloxacin/pharmacology, Microbial Sensitivity Tests, Mutation, Staphylococcus aureus/*drug effects/genetics, Tandem Mass Spectrometry	Pathogenicity
	27871033	Design, synthesis, anticancer, antimicrobial activities and molecular docking studies of novel quinoline bearing dihydropyridines.	Nkosi SM, Anand K, Anandakumar S, Singh S, Chuturgoon AA, Gengan RM	J Photochem Photobiol B	10.1016/j.jphotobiol.2016.10.009	2016	Anti-Infective Agents/chemistry/pharmacology, Antineoplastic Agents/chemistry/pharmacology, Dihydropyridines/chemistry, Drug Design, Molecular Docking Simulation, Quinolines/chemistry
	27873612	Activity of the antiseptic polyhexanide against meticillin-susceptible and meticillin-resistant Staphylococcus aureus.	Fabry W, Reimer C, Azem T, Aepinus C, Kock HJ, Vahlensieck W	J Glob Antimicrob Resist	10.1016/j.jgar.2013.05.007	2013
	27942357	The Effect of Ferula assa-foetida L and Carum copticum Hydroalcoholic Extract on the Expression Levels of Staphylococcus aureus Genes Involved in Quorum Sensing.	Jomehpour N, Eslami G, Khalili MB	Jundishapur J Microbiol	10.5812/jjm.33879	2016
Pathogenicity	28039103	iTRAQ-based proteome analysis of fluoroquinolone-resistant Staphylococcus aureus.	Thai VC, Lim TK, Le KPU, Lin Q, Nguyen TTH	J Glob Antimicrob Resist	10.1016/j.jgar.2016.11.003	2016	Bacterial Proteins/genetics/isolation & purification/metabolism, Chromatography, Liquid/methods, Drug Resistance, Bacterial/drug effects/genetics/physiology, Fluoroquinolones/pharmacology, Gene Expression Regulation, Bacterial/drug effects, Gene Ontology, Molecular Sequence Annotation, Protein Interaction Maps, Proteome/analysis, Proteomics/methods, Rec A Recombinases/genetics/metabolism, Ribosomes/metabolism, SOS Response, Genetics/drug effects, Staphylococcus aureus/drug effects/genetics/*metabolism, Stress, Physiological/drug effects, Tandem Mass Spectrometry/methods	Metabolism
	28066341	A New Synthetic Peptide Having Two Target of Antibacterial Action in E. coli ML35.	Barreto-Santamaria A, Curtidor H, Arevalo-Pinzon G, Herrera C, Suarez D, Perez WH, Patarroyo ME	Front Microbiol	10.3389/fmicb.2016.02006	2016
Phylogeny	28066367	Burkholderia paludis sp. nov., an Antibiotic-Siderophore Producing Novel Burkholderia cepacia Complex Species, Isolated from Malaysian Tropical Peat Swamp Soil.	Ong KS, Aw YK, Lee LH, Yule CM, Cheow YL, Lee SM	Front Microbiol	10.3389/fmicb.2016.02046	2016
Metabolism	28068600	Design, synthesis and antibacterial evaluation of novel pleuromutilin derivatives possessing piperazine linker.	Gao ML, Zeng J, Fang X, Luo J, Jin Z, Liu YH, Tang YZ	Eur J Med Chem	10.1016/j.ejmech.2017.01.004	2017	Anti-Bacterial Agents/chemical synthesis/chemistry/metabolism/pharmacology, Chemistry Techniques, Synthetic, Diterpenes/chemical synthesis/chemistry/metabolism/pharmacology, Drug Design, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Molecular Conformation, Molecular Docking Simulation, Piperazine, Piperazines/chemistry, Polycyclic Compounds, Ribosome Subunits, Large, Bacterial/chemistry/metabolism, Structure-Activity Relationship	Pathogenicity
Phylogeny	28214187	Microbiological analysis, antimicrobial activity, and heavy-metals content of Jordanian Ma'in hot-springs water.	Shakhatreh MAK, Jacob JH, Hussein EI, Masadeh MM, Obeidat SM, Juhmani AF, Abd Al-Razaq MA	J Infect Public Health	10.1016/j.jiph.2017.01.010	2017	Anti-Infective Agents/analysis, Bacteria/classification/genetics/isolation & purification, Cluster Analysis, DNA, Bacterial/chemistry/genetics, DNA, Ribosomal/chemistry/genetics, Hot Springs/chemistry/microbiology, Jordan, Metals, Heavy/analysis, Microbial Sensitivity Tests, Phylogeny, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA	Transcriptome
Pathogenicity	28257182	Poly(carboxylic acid)-Cyclodextrin/Anionic Porphyrin Finished Fabrics as Photosensitizer Releasers for Antimicrobial Photodynamic Therapy.	Castriciano MA, Zagami R, Casaletto MP, Martel B, Trapani M, Romeo A, Villari V, Sciortino MT, Grasso L, Guglielmino S, Scolaro LM, Mazzaglia A	Biomacromolecules	10.1021/acs.biomac.6b01752	2017	Anti-Infective Agents/pharmacology, Carboxylic Acids/chemistry, Cyclodextrins/chemistry, Microscopy, Electron, Scanning, Photochemotherapy, Photoelectron Spectroscopy, Photosensitizing Agents/pharmacology, Polypropylenes/chemistry, Porphyrins/chemistry/pharmacology, Pseudomonas aeruginosa/drug effects, Spectrometry, Fluorescence, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus/drug effects, Textiles
Pathogenicity	28277992	In situ development and application of natural coatings on non-absorbable sutures to reduce incision site infections.	Masood R, Hussain T, Umar M, Azeemullah, Areeb T, Riaz S	J Wound Care	10.12968/jowc.2017.26.3.115	2017	Anti-Infective Agents, Local/pharmacology, Bacterial Adhesion/drug effects, Chitosan, Coated Materials, Biocompatible, Curcuma, Humans, Hydrolysis, Oils, Volatile, Surgical Wound Infection/prevention & control, Sutures, Wound Healing
Pathogenicity	28361404	Antibacterial mode of action of violacein from Chromobacterium violaceum UTM5 against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).	Aruldass CA, Masalamany SRL, Venil CK, Ahmad WA	Environ Sci Pollut Res Int	10.1007/s11356-017-8855-2	2017	Anti-Bacterial Agents/isolation & purification/pharmacology/toxicity, Cell Line, Cell Membrane/drug effects/ultrastructure, Cell Survival/drug effects, Chromobacterium/chemistry, HEK293 Cells, Humans, Indoles/isolation & purification/pharmacology/toxicity, Methicillin-Resistant Staphylococcus aureus/drug effects/ultrastructure, Microbial Sensitivity Tests, Microbial Viability/drug effects, Staphylococcus aureus/*drug effects/ultrastructure	Enzymology
Pathogenicity	28436320	Antibacterial Activity of Desert Truffles from Saudi Arabia Against Staphylococcus aureus and Pseudomonas aeruginosa.	Schillaci D, Cusimano MG, Cascioferro SM, Di Stefano V, Arizza V, Chiaramonte M, Inguglia L, Bawadekji A, Davino S, Gargano ML, Venturella G	Int J Med Mushrooms	10.1615/IntJMedMushrooms.v19.i2.30	2017	Anti-Bacterial Agents/isolation & purification/pharmacology, Ascomycota/chemistry, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects, Saudi Arabia, Staphylococcus aureus/*drug effects	Enzymology
Pathogenicity	28441350	Synthesis and Bioactivity Evaluation of Novel 2-Salicyloylbenzofurans as Antibacterial Agents.	Phan PT, Nguyen TT, Nguyen HT, Le BN, Vu TT, Tran DC, Pham TN	Molecules	10.3390/molecules22050687	2017	Anti-Bacterial Agents/chemical synthesis/pharmacology, Benzofurans/chemical synthesis/pharmacology, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Salicylates/*chemical synthesis/pharmacology
	28460979	Distinct growth and extractive methods of Acmellaoleracea (L.) R.K. Jansen rising different concentrations of spilanthol: An important bioactive compound in human dietary.	Franca JV, Queiroz MSR, do Amaral BP, Simas NK, da Silva NCB, Leal ICR	Food Res Int	10.1016/j.foodres.2016.09.018	2016
Pathogenicity	28475376	Two new kaurane-type diterpenoids from Wedelia chinensis (Osbeck.) Merr.	Cai C, Zhang Y, Yang D, Hao X, Li S	Nat Prod Res	10.1080/14786419.2017.1317775	2017	Anti-Bacterial Agents/chemistry/pharmacology, Diterpenes, Diterpenes, Kaurane/chemistry/pharmacology, Drug Evaluation, Preclinical/methods, Escherichia coli/drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Molecular Structure, Pseudomonas aeruginosa/drug effects, Salmonella enterica/drug effects, Spectrophotometry, Ultraviolet, Staphylococcus aureus/drug effects, Wedelia/chemistry
Pathogenicity	28573239	THERAPEUTIC POTENTIALS OF ETHANOLIC EXTRACT OF LEAVES OF HOLARRHENA FLORIBUNDA (G. DON) DUR. AND SCHINZ (APOCYNACEAE).	Hoekou YP, Tchacondo T, Karou SD, Yerbanga RS, Achoribo E, Da O, Atakpama W, Batawila K	Afr J Tradit Complement Altern Med	10.21010/ajtcam.v14i2.24	2017	Animals, Anti-Bacterial Agents/pharmacology/therapeutic use, Antimalarials/pharmacology/therapeutic use, Bacteria/drug effects/growth & development, Female, Holarrhena, Infections/drug therapy/microbiology, Klebsiella pneumoniae/drug effects/growth & development, Malaria/blood/parasitology/prevention & control, Mice, Microbial Sensitivity Tests, Parasitemia/prevention & control, *Phytotherapy, Plant Extracts/pharmacology/therapeutic use, Plant Leaves, Salmonella typhi/drug effects/growth & development, Staphylococcus aureus/drug effects/growth & development
Pathogenicity	28583022	Implementation of the new VIRTUO blood culture system: evaluation and comparison to the 3D system using simulated blood cultures.	Miller N, Brassinne L, Allemeersch D	Acta Clin Belg	10.1080/17843286.2017.1331618	2017	Blood Culture/*instrumentation, Humans, Specimen Handling, Time Factors
Pathogenicity	28596137	Reshaping antibiotics through hydrophobic drug-bile acid ionic complexation enhances activity against Staphylococcus aureus biofilms.	Giovagnoli S, Pietrella D, Barberini L, Santi C, Carotti A, di Michele A, Ricci M	Int J Pharm	10.1016/j.ijpharm.2017.06.008	2017	Amikacin/pharmacology, Animals, Anti-Bacterial Agents/pharmacology, Bile Acids and Salts/chemistry, Biofilms/drug effects, Chick Embryo, Humans, Kanamycin/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Vancomycin/pharmacology
Pathogenicity	28623814	Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs.	El-Gohary NS, Shaaban MI	Eur J Med Chem	10.1016/j.ejmech.2017.05.064	2017	Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Antineoplastic Agents/chemical synthesis/chemistry/pharmacology, Aspergillus fumigatus/drug effects, Bacillus cereus/drug effects, Benzimidazoles/chemical synthesis/chemistry/pharmacology, Candida albicans/drug effects, Cell Line, Cell Proliferation/drug effects, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Escherichia coli/drug effects, Humans, Mice, Microbial Sensitivity Tests, Molecular Structure, Quorum Sensing/*drug effects, Staphylococcus aureus/drug effects, Structure-Activity Relationship
	28626456	Bactericidal Effect of Photodynamic Therapy, Alone or in Combination with Mupirocin or Linezolid, on Staphylococcus aureus.	Perez-Laguna V, Perez-Artiaga L, Lampaya-Perez V, Garcia-Luque I, Ballesta S, Nonell S, Paz-Cristobal MP, Gilaberte Y, Rezusta A	Front Microbiol	10.3389/fmicb.2017.01002	2017
Phylogeny	28647504	Antimicrobial investigation of selected soil actinomycetes isolated from unexplored regions of Kashmir Himalayas, India.	Shah AM, Shakeel-U-Rehman, Hussain A, Mushtaq S, Rather MA, Shah A, Ahmad Z, Khan IA, Bhat KA, Hassan QP	Microb Pathog	10.1016/j.micpath.2017.06.017	2017	Actinobacteria/chemistry/classification/genetics/isolation & purification, Anti-Infective Agents/chemistry/isolation & purification/pharmacology, DNA, Bacterial/genetics, Dactinomycin/analogs & derivatives/chemistry/isolation & purification/pharmacology, Drug Evaluation, Preclinical, Fermentation, India, Microbial Sensitivity Tests, Mycobacterium tuberculosis/drug effects, Phylogeny, RNA, Ribosomal, 16S/genetics, Soil, *Soil Microbiology, Staphylococcus aureus/drug effects, Streptomyces/chemistry/classification/genetics/isolation & purification	Enzymology
Pathogenicity	28652709	Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study.	Greimel F, Scheuerer C, Gessner A, Simon M, Kalteis T, Grifka J, Benditz A, Springorum HR, Schaumburger J	Drug Des Devel Ther	10.2147/DDDT.S138888	2017	Animals, Anti-Bacterial Agents/pharmacology, Bacterial Load, Biofilms/drug effects/growth & development, Colony Count, Microbial, Disease Models, Animal, Drug Resistance, Bacterial, Drug Therapy, Combination, Floxacillin/pharmacology, Fluoroquinolones/pharmacology, Joint Prosthesis/adverse effects, Male, Moxifloxacin, Prosthesis-Related Infections/diagnosis/drug therapy/microbiology, Rats, Wistar, Rifampin/pharmacology, Staphylococcal Infections/diagnosis/drug therapy/microbiology, Staphylococcus aureus/drug effects/growth & development, Time Factors
Pathogenicity	28710559	Aloe-emodin inhibits Staphylococcus aureus biofilms and extracellular protein production at the initial adhesion stage of biofilm development.	Xiang H, Cao F, Ming D, Zheng Y, Dong X, Zhong X, Mu D, Li B, Zhong L, Cao J, Wang L, Ma H, Wang T, Wang D	Appl Microbiol Biotechnol	10.1007/s00253-017-8403-5	2017	Anthraquinones/pharmacology, Anti-Bacterial Agents/pharmacology, Bacterial Adhesion/drug effects, Bacterial Proteins/metabolism, Biofilms/drug effects/growth & development, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Polysaccharides, Bacterial/antagonists & inhibitors, Staphylococcus aureus/*drug effects/physiology/ultrastructure	Biotechnology
Phylogeny	28785826	Saccharopolyspora hattusasensis sp. nov., isolated from soil.	Veyisoglu A, Saygin H, Tatar D, Bektas KI, Sahin N	Antonie Van Leeuwenhoek	10.1007/s10482-017-0921-8	2017	Bacterial Typing Techniques, Metabolomics/methods, Phylogeny, RNA, Ribosomal, 16S/genetics, Saccharopolyspora/chemistry/classification/genetics/isolation & purification, Sequence Analysis, DNA, Soil Microbiology	Transcriptome
Enzymology	28818482	Drawbacks of the use of cotrimoxazole in foreign-body infections.	El Haj C, Ribera A, Lloberas N, Tubau F, Ariza J, Murillo O	Enferm Infecc Microbiol Clin (Engl Ed)	10.1016/j.eimc.2017.07.005	2017	Animals, Anti-Bacterial Agents/pharmacokinetics/therapeutic use, Bacterial Load, Diffusion Chambers, Culture, Dose-Response Relationship, Drug, Foreign Bodies/complications, Microbial Sensitivity Tests, Rats, Staphylococcal Infections/drug therapy/microbiology, Thymidine/analysis, Treatment Failure, Trimethoprim, Sulfamethoxazole Drug Combination/pharmacokinetics/therapeutic use, Wound Infection/*drug therapy/etiology/metabolism	Metabolism
Pathogenicity	28842740	Lactococcus lactis as a safe and inexpensive source of bioactive silver composites.	Viorica RP, Pawel P, Kinga M, Michal Z, Katarzyna R, Boguslaw B	Appl Microbiol Biotechnol	10.1007/s00253-017-8443-x	2017	Animals, Anti-Bacterial Agents/pharmacology, Lactococcus lactis/metabolism, Metal Nanoparticles/chemistry, Microbial Sensitivity Tests, Milk/microbiology, Nanocomposites/chemistry, Proteus mirabilis/drug effects, Pseudomonas aeruginosa/drug effects, Silver/pharmacology, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, X-Ray Diffraction	Metabolism
Enzymology	28901070	[Bioactive quinolizidine alkaloids from Sophora tonkinensis].	Zhang Y, Hu WZ, Chen XZ, Peng YB, Song LY, Shi YS	Zhongguo Zhong Yao Za Zhi	10.4268/cjcmm20161215	2016	Alkaloids/isolation & purification, Anti-Bacterial Agents/isolation & purification, Phytochemicals/isolation & purification, Quinolizidines/isolation & purification, Quinolizines, Sophora/*chemistry, Staphylococcus aureus/drug effects	Phylogeny
	28914821	Biocompatibility of Titania Nanotube Coatings Enriched with Silver Nanograins by Chemical Vapor Deposition.	Piszczek P, Lewandowska Z, Radtke A, Jedrzejewski T, Kozak W, Sadowska B, Szubka M, Talik E, Fiori F	Nanomaterials (Basel)	10.3390/nano7090274	2017
Pathogenicity	28929962	[Determination of in vitro susceptibilities of Brucella spp. strains against 11 different antibacterial gents isolated from blood cultures].	Kesli R, Bilgin H, Yilmaz H	Mikrobiyol Bul	10.5578/mb.57362	2017	Anti-Bacterial Agents/pharmacology, Bacteremia/microbiology, Brucella/drug effects, Brucellosis/microbiology, Child, Humans, Microbial Sensitivity Tests/standards, Quality Control, Turkey
	28933732	The Bioactivity and Photocatalytic Properties of Titania Nanotube Coatings Produced with the Use of the Low-Potential Anodization of Ti6Al4V Alloy Surface.	Radtke A, Topolski A, Jedrzejewski T, Kozak W, Sadowska B, Wieckowska-Szakiel M, Szubka M, Talik E, Pleth Nielsen L, Piszczek P	Nanomaterials (Basel)	10.3390/nano7080197	2017
Pathogenicity	29017918	Comparative analysis of methicillin-sensitive and resistant Staphylococcus aureus exposed to emodin based on proteomic profiling.	Ji X, Liu X, Peng Y, Zhan R, Xu H, Ge X	Biochem Biophys Res Commun	10.1016/j.bbrc.2017.10.033	2017	Anti-Bacterial Agents/pharmacology, Bacterial Proteins/genetics/metabolism, Cathartics/pharmacology, Computational Biology, Drug Repositioning, Emodin/pharmacology, Gene Expression/drug effects, Gene Expression Profiling, Gene Regulatory Networks/drug effects, Methicillin-Resistant Staphylococcus aureus/*drug effects/genetics/growth & development/metabolism, Microbial Sensitivity Tests, Proteomics	Metabolism
Pathogenicity	29061748	In Vitro Evaluation of Povidone-Iodine and Chlorhexidine against Outbreak and Nonoutbreak Strains of Mycobacterium abscessus Using Standard Quantitative Suspension and Carrier Testing.	Cheng A, Sun HY, Tsai YT, Wu UI, Chuang YC, Wang JT, Sheng WH, Hsueh PR, Chen YC, Chang SC	Antimicrob Agents Chemother	10.1128/AAC.01364-17	2017	Anti-Infective Agents, Local/pharmacology, Chlorhexidine/pharmacology, Disease Outbreaks, Drug Evaluation, Preclinical/methods/standards, Humans, Microbial Sensitivity Tests, Mycobacterium Infections, Nontuberculous/epidemiology/microbiology, Mycobacterium abscessus/drug effects/isolation & purification, Povidone-Iodine/pharmacology, Suspensions	Enzymology
Stress	29061917	Production and mechanical properties of Ti-5Al-2.5Fe-xCu alloys for biomedical applications.	Yamanoglu R, Efendi E, Kolayli F, Uzuner H, Daoud I	Biomed Mater	10.1088/1748-605X/aa957d	2018	Alloys/chemistry, Anti-Bacterial Agents/chemistry, Biocompatible Materials/chemistry, Compressive Strength, Copper/chemistry, Corrosion, Escherichia coli, Hardness, HeLa Cells, Hot Temperature, Humans, Materials Testing, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Particle Size, Powders, Staphylococcus aureus, Stress, Mechanical, Tetrazolium Salts/chemistry, Thiazoles/chemistry, X-Ray Diffraction	Pathogenicity
Pathogenicity	29063889	Survivability and fitness cost of heterogeneous vancomycin-intermediate Staphylococcus aureus.	Singh A, Singh S, Singh J, Rahman M, Pathak A, Prasad KN	Indian J Med Microbiol	10.4103/ijmm.IJMM_17_311	2017	Desiccation, Genetic Fitness, Humans, Microbial Viability, Staphylococcus aureus/genetics/growth & development/physiology, Vancomycin Resistance
Pathogenicity	29238856	Anti-endotoxin mechanism of the KW4 peptide in inflammation in RAW 264.7 cells induced by LTA and drug-resistant Staphylococcus aureus 1630.	Lee JK, Park Y	Amino Acids	10.1007/s00726-017-2518-y	2017	Animals, Antimicrobial Cationic Peptides/chemical synthesis/pharmacology, Endotoxins/antagonists & inhibitors/biosynthesis, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Humans, Immunologic Deficiency Syndromes/drug therapy/immunology/microbiology/pathology, Inflammation/chemically induced/drug therapy/immunology/microbiology, Lipopolysaccharides/toxicity, Methicillin-Resistant Staphylococcus aureus/drug effects/pathogenicity, Mice, RAW 264.7 Cells, Staphylococcal Infections/drug therapy/immunology/microbiology/pathology, Teichoic Acids/toxicity
Enzymology	29378717	Identification of the In Vivo Pharmacokinetics and Pharmacodynamic Driver of Iclaprim.	Park JH, Craig W, Marchillo K, Huang DB, Andes DR	Antimicrob Agents Chemother	10.1128/AAC.02550-17	2018	Animals, Mice, Microbial Sensitivity Tests, Pyrimidines/pharmacokinetics/pharmacology, Staphylococcus aureus/drug effects, Streptococcus pneumoniae/drug effects, Thigh/microbiology, Trimethoprim/pharmacokinetics/pharmacology	Pathogenicity
Pathogenicity	29432912	In vitro evaluation of new 2-phenoxy-benzo[g][1,2,4]triazolo[1,5-a]quinazoline derivatives as antimicrobial agents.	Abuelizz HA, El-Dib RA, Marzouk M, Al-Salahi R	Microb Pathog	10.1016/j.micpath.2018.02.018	2018	Anti-Bacterial Agents/chemical synthesis/pharmacology, Anti-Infective Agents/chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Fungi/drug effects, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Microbial Sensitivity Tests, Molecular Structure, Quinazolines/chemical synthesis/*pharmacology, Structure-Activity Relationship
Metabolism	29526203	Staphylococcus aureus undergoes major transcriptional reorganization during growth with Enterococcus faecalis in milk.	Vicosa GN, Botta C, Ferrocino I, Bertolino M, Ventura M, Nero LA, Cocolin L	Food Microbiol	10.1016/j.fm.2018.01.007	2018	Animals, Bacterial Proteins/genetics/metabolism, Cattle, Cheese/microbiology, Coculture Techniques, Enterococcus faecalis/growth & development, Food Microbiology, Milk/microbiology, Staphylococcus aureus/genetics/growth & development/metabolism, Transcription, Genetic	Biotechnology
Pathogenicity	29653134	The optimal ethanol lock therapy regimen for treatment of biofilm-associated catheter infections: an in-vitro study.	Alonso B, Perez-Granda MJ, Rodriguez-Huerta A, Rodriguez C, Bouza E, Guembe M	J Hosp Infect	10.1016/j.jhin.2018.04.007	2018	Bacteria/drug effects/growth & development, Biofilms/drug effects/growth & development, Candida/drug effects/growth & development, Catheter-Related Infections/prevention & control, Catheters/microbiology, Disinfectants/administration & dosage, Ethanol/administration & dosage, Heparin/administration & dosage, Humans, Infection Control/methods, Metabolism/drug effects, Staining and Labeling/methods, Tetrazolium Salts/metabolism	Metabolism
Metabolism	29722184	Synthesis and antibacterial activities of novel pleuromutilin derivatives bearing an aminothiophenol moiety.	Zhang ZS, Huang YZ, Luo J, Jin Z, Liu YH, Tang YZ	Chem Biol Drug Des	10.1111/cbdd.13328	2018	Animals, Anti-Bacterial Agents/chemical synthesis/metabolism/pharmacology/therapeutic use, Bacterial Proteins/chemistry/metabolism, Binding Sites, Deinococcus/enzymology, Diterpenes/chemistry/metabolism/pharmacology/therapeutic use, Escherichia coli/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Microbial Sensitivity Tests, Molecular Docking Simulation, Peptidyl Transferases/chemistry/metabolism, Phenols/chemistry, Polycyclic Compounds, Protein Structure, Tertiary, Ribosome Subunits, Large, Bacterial/chemistry/metabolism, Staphylococcal Infections/drug therapy/pathology/veterinary, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Sulfhydryl Compounds/chemistry	Pathogenicity
	29805849	Herbal extracts in the treatment of Diabetic Foot Syndrome.	Kustova T, Karpenyuk T, Goncharova A, Mamonov L, Ross S	Cent Asian J Glob Health	10.5195/cajgh.2013.86	2014
Pathogenicity	29847738	Inhibitory Effect of 2R,3R-Dihydromyricetin on Biofilm Formation by Staphylococcus aureus.	Wu YP, Bai JR, Grosu E, Zhong K, Liu LJ, Tang MM, Huang YN, Gao H	Foodborne Pathog Dis	10.1089/fpd.2017.2405	2018	Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Flavonols/pharmacology, Food Contamination/prevention & control, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Stainless Steel, Staphylococcus aureus/drug effects
Pathogenicity	29945177	The antimicrobial spectrum of lysozyme broadened by reductive modification.	Liu J, Wang N, Liu Y, Jin Y, Ma M	Poult Sci	10.3382/ps/pey245	2018	Animals, Anti-Bacterial Agents/chemistry/pharmacology, Chickens, Disulfides/chemistry, Egg White/chemistry, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Muramidase/chemistry/pharmacology, Oxidation-Reduction, Sulfites/chemistry
Metabolism	30007045	Covalent Whey Protein-Rosmarinic Acid Interactions: A Comparison of Alkaline and Enzymatic Modifications on Physicochemical, Antioxidative, and Antibacterial Properties.	Ali M, Keppler JK, Coenye T, Schwarz K	J Food Sci	10.1111/1750-3841.14222	2018	Anti-Bacterial Agents, Antioxidants, Chemical Phenomena, Cinnamates/chemistry/metabolism, Depsides/chemistry/metabolism, Hydrogen-Ion Concentration, Monophenol Monooxygenase/metabolism, Phenols, Whey Proteins/chemistry/metabolism
Pathogenicity	30041003	Phenotype and RNA-seq-Based transcriptome profiling of Staphylococcus aureus biofilms in response to tea tree oil.	Zhao X, Liu Z, Liu Z, Meng R, Shi C, Chen X, Bu X, Guo N	Microb Pathog	10.1016/j.micpath.2018.07.027	2018	Amino Acids/genetics/metabolism, Anti-Bacterial Agents/pharmacology, Bacterial Adhesion/drug effects, Biofilms/drug effects/growth & development, Gene Expression Profiling/methods, Gene Expression Regulation, Bacterial/drug effects, Genes, Bacterial/genetics, Metabolic Networks and Pathways/drug effects/genetics, Microbial Sensitivity Tests, Phenotype, RNA, Bacterial/analysis, Sequence Analysis, RNA, Staphylococcus aureus/drug effects/genetics, Tea Tree Oil/*pharmacology	Transcriptome
Pathogenicity	30046488	Synthesis and characterization of ZnO phytonanocomposite using Strychnos nux-vomica L. (Loganiaceae) and antimicrobial activity against multidrug-resistant bacterial strains from diabetic foot ulcer.	Steffy K, Shanthi G, Maroky AS, Selvakumar S	J Adv Res	10.1016/j.jare.2017.11.001	2017
	30057579	Efficient Exploitation of Multiple Novel Bacteriocins by Combination of Complete Genome and Peptidome.	Yi L, Luo L, Lu X	Front Microbiol	10.3389/fmicb.2018.01567	2018
Pathogenicity	30087309	Synthesis and Spectrum of Biological Activities of Novel N-arylcinnamamides.	Pospisilova S, Kos J, Michnova H, Kapustikova I, Strharsky T, Oravec M, Moricz AM, Bakonyi J, Kauerova T, Kollar P, Cizek A, Jampilek J	Int J Mol Sci	10.3390/ijms19082318	2018	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antifungal Agents/chemical synthesis/chemistry/pharmacology, Antitubercular Agents/chemical synthesis/chemistry/pharmacology, Biofilms/drug effects, Chemistry Techniques, Synthetic, Cinnamates/chemical synthesis/chemistry/pharmacology, Fusarium/drug effects, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects/physiology, Microbial Sensitivity Tests, Mycobacterium tuberculosis/drug effects/physiology, Plant Diseases/microbiology, Plants/microbiology, Staphylococcal Infections/drug therapy, Staphylococcus aureus/drug effects/physiology, Tuberculosis/drug therapy
Biotechnology	30095422	Simplistic approach in extracellular synthesis of silver nanoparticles via bioreducing potential of Planococcus plakortidis strain BGCC-51 isolated from dye industry effluent soil.	Chokriwal A, Stephen BJ, Jain D, Singh A	IET Nanobiotechnol	10.1049/iet-nbt.2017.0251	2018	Biotechnology, Coloring Agents, Extracellular Space/metabolism, Metal Nanoparticles/chemistry, Oxidation-Reduction, Planococcaceae/chemistry/isolation & purification/metabolism, Silver/*chemistry, Soil Microbiology, Textile Industry	Metabolism
Pathogenicity	30104447	Biosynthesis of Ag, Se, and ZnO nanoparticles with antimicrobial activities against resistant pathogens using waste isolate Streptomyces enissocaesilis.	Shaaban M, El-Mahdy AM	IET Nanobiotechnol	10.1049/iet-nbt.2017.0213	2018	Anti-Infective Agents/chemistry/isolation & purification/metabolism/pharmacology, Antibiosis, Drug Resistance, Microbial/drug effects, Escherichia coli/drug effects, Klebsiella pneumoniae/drug effects, Metal Nanoparticles/chemistry, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Microscopy, Electron, Transmission, Particle Size, Pseudomonas aeruginosa/drug effects, Selenium/isolation & purification/metabolism, Silver/isolation & purification/metabolism, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus/drug effects, Streptomyces/chemistry/isolation & purification/metabolism, Zinc Oxide/isolation & purification/*metabolism	Enzymology
	30116728	Combination of Cloxacillin and Essential Oil of Melaleuca armillaris as an Alternative Against Staphylococcus aureus.	Buldain D, Buchamer AV, Marchetti ML, Aliverti F, Bandoni A, Mestorino N	Front Vet Sci	10.3389/fvets.2018.00177	2018
Metabolism	30174025	Antimicrobial and antioxidant activities of phenolic metabolites from flavonoid-producing yeast: Potential as natural food preservatives.	Ng KR, Lyu X, Mark R, Chen WN	Food Chem	10.1016/j.foodchem.2018.07.077	2018	Anti-Infective Agents, Antioxidants, Flavonoids, Food Preservation/methods, Food Preservatives/metabolism, Phenols/metabolism, Saccharomyces cerevisiae/*metabolism, Staphylococcus aureus
	30187740	Antimicrobial Activity and Phytochemical Screening of Sarcocolla Gum Resin.	Ababutain IM	Pak J Biol Sci	10.3923/pjbs.2017.571.576	2017
Pathogenicity	30262284	Potential bactericidal activity of S. nux-vomica-ZnO nanocomposite against multidrug-resistant bacterial pathogens and wound-healing properties.	Steffy K, Shanthi G, Maroky AS, Selvakumar S	J Trace Elem Med Biol	10.1016/j.jtemb.2018.07.009	2018	Animals, Anti-Bacterial Agents/adverse effects/chemistry/pharmacology, Cell Line, Escherichia coli/drug effects, Flow Cytometry, HEK293 Cells, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Microbial Sensitivity Tests, Nanocomposites/adverse effects/chemistry, Staphylococcus aureus/drug effects, Wound Healing/drug effects
	30263461	Antimicrobial activity of a novel furan fatty acid, 7,10-epoxyoctadeca-7,9-dienoic acid against methicillin-resistant Staphylococcus aureus.	Dasagrandhi C, Ellamar JB, Kim YS, Kim HR	Food Sci Biotechnol	10.1007/s10068-016-0257-6	2016
Pathogenicity	30267931	Impact of different pathophysiological conditions on antimicrobial activity of glycopeptides in vitro.	Oesterreicher Z, Eberl S, Nussbaumer-Proell A, Peilensteiner T, Zeitlinger M	Clin Microbiol Infect	10.1016/j.cmi.2018.09.004	2018	Albumins, Aminoglycosides/pharmacology, Anti-Infective Agents/pharmacology, Glycopeptides/pharmacology, Humans, Hydrogen-Ion Concentration, Lipoglycopeptides/pharmacology, Microbial Sensitivity Tests/methods, Staphylococcal Infections/microbiology, Staphylococcus aureus/*drug effects/isolation & purification, Teicoplanin/pharmacology, Temperature, Vancomycin/pharmacology	Enzymology
	30288618	Antimicrobial and Cytotoxicity Effects of Synthesized Silver Nanoparticles from Punica granatum Peel Extract.	Devanesan S, AlSalhi MS, Balaji RV, Ranjitsingh AJA, Ahamed A, Alfuraydi AA, AlQahtani FY, Aleanizy FS, Othman AH	Nanoscale Res Lett	10.1186/s11671-018-2731-y	2018
	30323791	Sarconesin: Sarconesiopsis magellanica Blowfly Larval Excretions and Secretions With Antibacterial Properties.	Diaz-Roa A, Patarroyo MA, Bello FJ, Da Silva PI Jr	Front Microbiol	10.3389/fmicb.2018.02249	2018
Enzymology	30373794	Use of Translational Pharmacokinetic/Pharmacodynamic Infection Models To Understand the Impact of Neutropenia on the Efficacy of Tedizolid Phosphate.	Xiao J, Gill C, Liang L, Liu J, Wu J, Feng HP, Flanagan S, Tan C, Flattery A	Antimicrob Agents Chemother	10.1128/AAC.00822-18	2018	Animals, Anti-Bacterial Agents/pharmacokinetics/pharmacology, Disease Models, Animal, Linezolid/pharmacokinetics/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Microbial Sensitivity Tests, Neutropenia/metabolism, Organophosphates/pharmacokinetics/pharmacology, Oxazoles/pharmacokinetics/pharmacology, Staphylococcal Skin Infections/*drug therapy/microbiology	Pathogenicity
Pathogenicity	30406042	Identification of Anti-staphylococcal and Anti-biofilm Compounds by Repurposing the Medicines for Malaria Venture Pathogen Box.	Bhandari V, Chakraborty S, Brahma U, Sharma P	Front Cell Infect Microbiol	10.3389/fcimb.2018.00365	2018	Animals, Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology/toxicity, Biofilms/drug effects, Cell Survival/drug effects, Drug Evaluation, Preclinical, Drug Repositioning, Mice, Microbial Sensitivity Tests, RAW 264.7 Cells/drug effects, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects	Enzymology
Phylogeny	30563178	Mollicellins O(-)R, Four New Depsidones Isolated from the Endophytic Fungus Chaetomium sp. Eef-10.	Ouyang J, Mao Z, Guo H, Xie Y, Cui Z, Sun J, Wu H, Wen X, Wang J, Shan T	Molecules	10.3390/molecules23123218	2018	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology, Antioxidants/chemistry/pharmacology, Cell Line, Tumor, Chaetomium/chemistry/metabolism, Depsides/chemistry/isolation & purification/pharmacology, Endophytes/chemistry/metabolism, Humans, Lactones/chemistry/isolation & purification/pharmacology, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Molecular Structure	Enzymology
Pathogenicity	30572157	Transcriptome analysis of silver nanoparticles treated Staphylococcus aureus reveals potential targets for biofilm inhibition.	Singh N, Rajwade J, Paknikar KM	Colloids Surf B Biointerfaces	10.1016/j.colsurfb.2018.12.032	2018	Anti-Bacterial Agents/administration & dosage/chemistry, Biofilms/drug effects, Biomarkers/analysis/metabolism, Gene Expression Profiling, High-Throughput Nucleotide Sequencing, Metal Nanoparticles/administration & dosage/chemistry, Quorum Sensing, Silver/chemistry, Staphylococcal Infections/drug therapy/microbiology, Staphylococcus aureus/*drug effects/genetics, Virulence/drug effects	Transcriptome
Pathogenicity	30602287	Chemical composition and antimicrobial activity of essential oil of Helichrysum italicum (Roth) G. Don fil. (Asteraceae) from Montenegro.	Oliva A, Garzoli S, Sabatino M, Tadic V, Costantini S, Ragno R, Bozovic M	Nat Prod Res	10.1080/14786419.2018.1538218	2019	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Asteraceae, Bacteria/drug effects, Bicyclic Monoterpenes, Candida/drug effects, Gas Chromatography-Mass Spectrometry, Helichrysum/chemistry, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Monocyclic Sesquiterpenes, Montenegro, Oils, Volatile/*chemistry/pharmacology, Terpenes/chemistry/isolation & purification/pharmacology	Enzymology
Enzymology	30618287	Two new aromatic polyketides from a deep-sea fungus Penicillium sp. SCSIO 06720.	Guo C, Lin XP, Liao SR, Yang B, Zhou XF, Yang XW, Tian XP, Wang JF, Liu YH	Nat Prod Res	10.1080/14786419.2018.1553880	2019	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Anti-HIV Agents/chemistry/isolation & purification/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Molecular Structure, Penicillium/chemistry, Polyketides/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects	Phylogeny
Metabolism	30621590	Novel linear lipopeptide paenipeptin C' binds to lipopolysaccharides and lipoteichoic acid and exerts bactericidal activity by the disruption of cytoplasmic membrane.	Moon SH, Huang E	BMC Microbiol	10.1186/s12866-018-1381-7	2019	Anti-Bacterial Agents/metabolism/pharmacology, Cell Membrane/drug effects, Lipopeptides/isolation & purification/metabolism/pharmacology, Lipopolysaccharides/metabolism, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Teichoic Acids/metabolism	Pathogenicity
Enzymology	30621792	Staphylococcus aureus biofilm organization modulated by YycFG two-component regulatory pathway.	Wu S, Huang F, Zhang H, Lei L	J Orthop Surg Res	10.1186/s13018-018-1055-z	2019	Adult, Bacterial Proteins/isolation & purification/physiology, Biofilms/growth & development, Female, Humans, Male, Methicillin-Resistant Staphylococcus aureus/isolation & purification/physiology, Middle Aged, Signal Transduction/physiology, Staphylococcal Infections/diagnosis/genetics, Staphylococcus aureus/isolation & purification/physiology, Young Adult	Phylogeny
Pathogenicity	30630320	Antimicrobial effect of novel hydrogel matrix based on natural polysaccharide Sterculia urens.	Lipovy B, Holoubek J, Vacek L, Ruzicka F, Nedomova E, Postulkova H, Vojtova L	Epidemiol Mikrobiol Imunol	107027		Anti-Infective Agents/pharmacology, Bacteria/drug effects, Hydrogels/chemistry, Microbial Sensitivity Tests, Polysaccharides/pharmacology, *Sterculia/chemistry
Pathogenicity	30682527	Antibacterial activity of Morinda citrifolia Linneo seeds against Methicillin-Resistant Staphylococcus spp.	De La Cruz-Sanchez NG, Gomez-Rivera A, Alvarez-Fitz P, Ventura-Zapata E, Perez-Garcia MD, Aviles-Flores M, Gutierrez-Roman AS, Gonzalez-Cortazar M	Microb Pathog	10.1016/j.micpath.2019.01.030	2019	Anti-Bacterial Agents/chemistry/pharmacology, Butyrophenones/pharmacology, Dioxins/pharmacology, Fatty Acids/pharmacology, Gas Chromatography-Mass Spectrometry, Magnetic Resonance Spectroscopy, Medicine, Traditional, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Morinda/chemistry, Plant Extracts/chemistry/pharmacology, Scopoletin/pharmacology, Seeds/chemistry, Staphylococcus/*drug effects, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Staphylococcus haemolyticus/drug effects
Pathogenicity	30687870	Impact of erythrocytes on bacterial growth and antimicrobial activity of selected antibiotics.	Nussbaumer-Proll AK, Knotzer S, Eberl S, Reiter B, Stimpfl T, Jager W, Poschner S, Zeitlinger M	Eur J Clin Microbiol Infect Dis	10.1007/s10096-018-03452-4	2019	Anti-Bacterial Agents/metabolism/pharmacology, Bacteria/drug effects/growth & development, Ciprofloxacin/metabolism/pharmacology, Erythrocytes/metabolism/*physiology, Escherichia coli/drug effects/growth & development, Humans, Meropenem/metabolism/pharmacology, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects/growth & development, Staphylococcus aureus/drug effects/growth & development, Tigecycline/metabolism/pharmacology	Metabolism
Pathogenicity	30688429	Antibiofilm Nitric Oxide-Releasing Polydopamine Coatings.	Sadrearhami Z, Shafiee FN, Ho KKK, Kumar N, Krasowska M, Blencowe A, Wong EHH, Boyer C	ACS Appl Mater Interfaces	10.1021/acsami.8b16853	2019	Anti-Bacterial Agents/chemistry/pharmacology, Biofilms/drug effects/growth & development, Coated Materials, Biocompatible/chemistry/pharmacology, Indoles/chemistry/pharmacology, Nitric Oxide/chemistry/pharmacology, Polymers/chemistry/pharmacology, Pseudomonas aeruginosa/physiology, Staphylococcus aureus/physiology
Pathogenicity	30761529	Fabrication and physicochemical and antibacterial properties of ethyl cellulose-structured cinnamon oil oleogel: relation between ethyl cellulose viscosity and oleogel performance.	Zhang K, Wang W, Wang X, Cheng S, Zhou J, Wu Z, Li Y	J Sci Food Agric	10.1002/jsfa.9636	2019	Anti-Bacterial Agents/chemistry/pharmacology, Cellulose/analogs & derivatives/chemistry, Cinnamomum zeylanicum/chemistry, Escherichia coli O157/drug effects/growth & development, Listeria monocytogenes/drug effects/growth & development, Microbial Sensitivity Tests, Oils, Volatile/chemistry/pharmacology, Organic Chemicals/chemistry/pharmacology, Plant Oils/chemistry/pharmacology, Staphylococcus aureus/drug effects/growth & development, Viscosity
	30905995	A Comparison of Bacterial Adhesion and Biofilm Formation on Commonly Used Orthopaedic Metal Implant Materials: An In vitro Study.	Malhotra R, Dhawan B, Garg B, Shankar V, Nag TC	Indian J Orthop	10.4103/ortho.IJOrtho_66_18	2019
Pathogenicity	31148374	Antimicrobial effects of local anaesthetics.	Kesici U, Demirci M, Kesici S	Int Wound J	10.1111/iwj.13153	2019	Anesthetics, Local/pharmacology/therapeutic use, Anti-Bacterial Agents/pharmacology/therapeutic use, Escherichia coli/drug effects, Humans, Lidocaine/pharmacology/therapeutic use, Mupirocin/pharmacology/therapeutic use, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/*drug effects
Phylogeny	31159162	Sarconesin II, a New Antimicrobial Peptide Isolated from Sarconesiopsis magellanica Excretions and Secretions.	Diaz-Roa A, Espinoza-Culupu A, Torres-Garcia O, Borges MM, Avino IN, Alves FL, Miranda A, Patarroyo MA, da Silva PI Jr, Bello FJ	Molecules	10.3390/molecules24112077	2019	Amino Acid Sequence, Animals, Anti-Bacterial Agents/biosynthesis/chemistry/isolation & purification/pharmacology, Antimicrobial Cationic Peptides/biosynthesis/chemistry/isolation & purification/pharmacology, Bacteria/drug effects, Chemical Phenomena, Chromatography, High Pressure Liquid, Diptera/*metabolism, Dose-Response Relationship, Drug, Mass Spectrometry, Microbial Sensitivity Tests, Models, Molecular, Protein Conformation, Structure-Activity Relationship	Enzymology
Metabolism	31183878	Pharmacokinetic profile of amoxicillin and its glucuronide-like metabolite when administered subcutaneously to koalas (Phascolarctos cinereus).	Kimble B, Vogelnest L, Gharibi S, Izes AM, Govendir M	J Vet Pharmacol Ther	10.1111/jvp.12767	2019	Amoxicillin/administration & dosage/blood/pharmacokinetics, Animals, Anti-Bacterial Agents/administration & dosage/blood/pharmacokinetics, Area Under Curve, Blood Proteins/metabolism, Chromatography, Liquid/veterinary, Escherichia coli/drug effects/growth & development, Female, Glucuronides/metabolism, Half-Life, Injections, Subcutaneous/veterinary, Male, Mass Spectrometry/veterinary, Phascolarctidae/*metabolism, Protein Binding, Staphylococcus aureus/drug effects/growth & development	Enzymology
Enzymology	31206719	Pharmacokinetics and pharmacodynamics of intramammary cefquinome in lactating goats with and without experimentally induced Staphylococcus aureus mastitis.	El Badawy SA, Amer AMM, Kamel GM, Eldeib KM, Constable PD	J Vet Pharmacol Ther	10.1111/jvp.12790	2019	Animals, Anti-Bacterial Agents/therapeutic use, Cephalosporins/pharmacokinetics/therapeutic use, Female, Goat Diseases/drug therapy/microbiology, Goats, Lactation, Mastitis/drug therapy/microbiology/veterinary, Milk/chemistry, Staphylococcal Infections/drug therapy/microbiology/*veterinary, Staphylococcus aureus
Pathogenicity	31244223	Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models.	Su M, Qiu L, Deng Y, Ruiz CH, Rudolf JD, Dong LB, Feng X, Cameron MD, Shen B, Duan Y, Huang Y	Mol Pharm	10.1021/acs.molpharmaceut.9b00293	2019	Adamantane/administration & dosage/therapeutic use, Aminobenzoates/administration & dosage/therapeutic use, Anilides/administration & dosage/therapeutic use, Animals, Anti-Bacterial Agents/administration & dosage/therapeutic use, Biofilms/drug effects, Burns/drug therapy/microbiology, Disease Models, Animal, Drug Resistance, Bacterial/drug effects, Drug Stability, Fatty Acid Synthase, Type II/antagonists & inhibitors, Fatty Acid Synthesis Inhibitors/administration & dosage/therapeutic use, Female, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Microsomes/drug effects, Peritonitis/drug therapy/microbiology, Prodrugs/administration & dosage/therapeutic use, Staphylococcal Skin Infections/drug therapy/microbiology, Sulfides, Treatment Outcome
Pathogenicity	31248162	The Antibiofilm Effect of a Medical Device Containing TIAB on Microorganisms Associated with Surgical Site Infection.	Puca V, Traini T, Guarnieri S, Carradori S, Sisto F, Macchione N, Muraro R, Mincione G, Grande R	Molecules	10.3390/molecules24122280	2019	Anti-Bacterial Agents/chemistry/pharmacology, Bacteria/drug effects/ultrastructure, Biofilms/drug effects, Coated Materials, Biocompatible, Equipment and Supplies/adverse effects/microbiology, Humans, Microbial Sensitivity Tests, Silver Compounds/chemistry, Surgical Wound Infection/etiology
Pathogenicity	31308654	Investigation of silver nanoparticles on titanium surface created by ion implantation technology.	Lampe I, Beke D, Biri S, Csarnovics I, Csik A, Dombradi Z, Hajdu P, Hegedus V, Racz R, Varga I, Hegedus C	Int J Nanomedicine	10.2147/IJN.S197782	2019	Animals, Anti-Bacterial Agents/pharmacology, Cell Survival/drug effects, Coated Materials, Biocompatible/pharmacology, Dental Implantation/methods, Ions, Metal Nanoparticles/chemistry, Microbial Sensitivity Tests, Particle Size, Silver/pharmacology, Staphylococcus aureus/drug effects, Stem Cells/cytology/drug effects/ultrastructure, Surface Properties, Titanium/pharmacology
Cultivation	31315953	Determination of MIC Quality Control Ranges for the Novel Gyrase Inhibitor Zoliflodacin.	Miller AA, Traczewski MM, Huband MD, Bradford PA, Mueller JP	J Clin Microbiol	10.1128/JCM.00567-19	2019	Anti-Bacterial Agents/pharmacology, Barbiturates/pharmacology, Culture Media, Enzyme Inhibitors/pharmacology, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Isoxazoles, Microbial Sensitivity Tests/methods/standards, Morpholines, Oxazolidinones, Quality Control, Spiro Compounds/pharmacology	Pathogenicity
Pathogenicity	31345195	In vitro evaluation of methicillin-resistant and methicillin-sensitive Staphylococcus aureus susceptibility to Saudi honeys.	Hussain MB, Kamel YM, Ullah Z, Jiman-Fatani AAM, Ahmad AS	BMC Complement Altern Med	10.1186/s12906-019-2603-8	2019	Anti-Bacterial Agents/analysis/pharmacology, Drug Evaluation, Preclinical, Escherichia coli/drug effects/growth & development, Honey/analysis, Humans, Methicillin Resistance, Methicillin-Resistant Staphylococcus aureus/*drug effects/growth & development, Microbial Sensitivity Tests, Saudi Arabia, Staphylococcus aureus/drug effects
Pathogenicity	31357964	Prenylated flavonoid-enriched fraction from Maclura tinctoria shows biological activity against Staphylococcus aureus and protects Galleria mellonella larvae from bacterial infection.	das Chagas Almeida A, Azevedo Rodrigues L, Dos Santos Paulino G, Pereira Aguilar A, Andrade Almeida A, Olavo Ferreira S, Brandao GC, Viana Leite JP, de Oliveira Barros Ribon A	BMC Complement Altern Med	10.1186/s12906-019-2600-y	2019	Animals, Anti-Bacterial Agents/administration & dosage/chemistry, Brazil, Disease Models, Animal, Flavonoids/administration & dosage/chemistry, Humans, Larva/growth & development/microbiology, Maclura/chemistry, Microbial Sensitivity Tests, Moths/growth & development/microbiology, Plant Extracts/administration & dosage/chemistry, Protective Agents/administration & dosage/chemistry, Staphylococcal Infections/microbiology/prevention & control, Staphylococcus aureus/drug effects
Pathogenicity	31407479	Antibacterial effects of lidocaine and adrenaline.	Kesici S, Demirci M, Kesici U	Int Wound J	10.1111/iwj.13182	2019	Epinephrine/pharmacology, Escherichia coli/drug effects, Humans, In Vitro Techniques, Lidocaine/pharmacology, Microbial Sensitivity Tests/methods, Pseudomonas aeruginosa/drug effects, Sensitivity and Specificity, Staphylococcus aureus/*drug effects
Pathogenicity	31407480	Bacterial inhibition efficiency of prilocaine and bupivacaine.	Kesici S, Demirci M, Kesici U	Int Wound J	10.1111/iwj.13180	2019	Bupivacaine/pharmacology, Escherichia coli/drug effects, Humans, In Vitro Techniques, Microbial Sensitivity Tests, Prilocaine/pharmacology, Pseudomonas aeruginosa/drug effects, Sensitivity and Specificity, Staphylococcus aureus/*drug effects, Statistics, Nonparametric
Pathogenicity	31419741	Design, synthesis and biological evaluation of novel pleuromutilin derivatives possessing acetamine phenyl linker.	Jin Z, Wang L, Gao H, Zhou YH, Liu YH, Tang YZ	Eur J Med Chem	10.1016/j.ejmech.2019.111594	2019	Aniline Compounds/chemical synthesis/chemistry/pharmacology/therapeutic use, Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology/therapeutic use, Diterpenes/chemical synthesis/chemistry/pharmacology/therapeutic use, Drug Design, Escherichia coli/drug effects, Escherichia coli Infections/drug therapy, Female, Humans, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Inbred ICR, Polycyclic Compounds/chemical synthesis/chemistry/pharmacology/therapeutic use, Staphylococcal Infections/drug therapy/microbiology, Staphylococcus aureus/drug effects
Metabolism	31437692	Impact of co-cultivation with Enterococcus faecalis over growth, enterotoxin production and gene expression of Staphylococcus aureus in broth and fresh cheeses.	Nogueira Vicosa G, Vieira Botelho C, Botta C, Bertolino M, Fernandes de Carvalho A, Nero LA, Cocolin L	Int J Food Microbiol	10.1016/j.ijfoodmicro.2019.108291	2019	Animals, Antibiosis/physiology, Biological Control Agents/metabolism, Cheese/microbiology, Coculture Techniques, Enterococcus faecalis/metabolism, Enterotoxins/biosynthesis/genetics, Food Safety/methods, Gene Expression, Milk/microbiology, Staphylococcal Infections/prevention & control, Staphylococcus aureus/metabolism, Virulence Factors/metabolism	Biotechnology
Pathogenicity	31438836	Recent Patents on Impact of Lipopeptide on the Biofilm Formation onto Titanium and Stainless Steel Surfaces.	Pires MEE, Parreira AG, Silva TNL, Colares HC, da Silva JA, de Magalhaes JT, Galdino AS, Goncalves DB, Granjeiro JM, Granjeiro PA	Recent Pat Biotechnol	10.2174/1872208313666190822150323	2020	Bacillus subtilis/chemistry, Bacterial Adhesion/drug effects, Bacterial Proteins/pharmacology, Biofilms/drug effects, Escherichia coli/drug effects, Humans, Lipopeptides/pharmacology, Patents as Topic, Prosthesis Design, Prosthesis-Related Infections/prevention & control, Stainless Steel, Staphylococcus aureus/drug effects, Surface Properties, Titanium
	31488167	Microwaves increase the effectiveness of systemic antibiotic treatment in acute bone infection: experimental study in a rat model.	Qi XY, Qiu XS, Jiang JY, Chen YX, Tang LM, Shi HF	J Orthop Surg Res	10.1186/s13018-019-1342-3	2019	Animals, Anti-Bacterial Agents, Bone Diseases, Infectious/diagnostic imaging/therapy, Combined Modality Therapy/methods, Disease Models, Animal, Male, Microwaves/therapeutic use, Radiofrequency Therapy/methods, Rats, Treatment Outcome
	31523409	Inhibitory effect of probiotic yeast Saccharomyces cerevisiae on biofilm formation and expression of alpha-hemolysin and enterotoxin A genes of Staphylococcus aureus.	Saidi N, Owlia P, Marashi SMA, Saderi H	Iran J Microbiol		2019
	31579244	Development, optimization, standardization, and validation of a simple in-house agar gradient method to determine minimum inhibitory concentration of vancomycin for Staphylococcus aureus.	Rai S, Tandon M, Singh NP, Manchanda V, Kaur IR	J Lab Physicians	10.4103/JLP.JLP_11_19	2019
Pathogenicity	31607570	Vancomycin-loaded oxidized hyaluronic acid and adipic acid dihydrazide hydrogel: Bio-compatibility, drug release, antimicrobial activity, and biofilm model.	Liao CH, Chen CS, Chen YC, Jiang NE, Farn CJ, Shen YS, Hsu ML, Chang CH	J Microbiol Immunol Infect	10.1016/j.jmii.2019.08.008	2019	Adipates/chemistry, Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Cell Line, Humans, Hyaluronic Acid/chemistry, Hydrogels/chemistry, Mesenchymal Stem Cells/drug effects/microbiology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Prosthesis-Related Infections/drug therapy/microbiology, Vancomycin/chemistry/pharmacology
Pathogenicity	31710159	In vitro antimicrobial activity of narasin and monensin in combination with adjuvants against pathogens associated with canine otitis externa.	Chan WY, Hickey EE, Khazandi M, Page SW, Trott DJ, Hill PB	Vet Dermatol	10.1111/vde.12803	2019	Adjuvants, Pharmaceutic/pharmacology, Animals, Anti-Bacterial Agents/pharmacology, Bacteria/drug effects/pathogenicity, Biofilms/drug effects, Dog Diseases/drug therapy/microbiology, Dogs, Drug Synergism, Ionophores/pharmacology, Microbial Sensitivity Tests, Monensin/pharmacology, Otitis Externa/drug therapy/microbiology/veterinary, Proteus mirabilis/drug effects, Pseudomonas aeruginosa/drug effects, Pyrans/pharmacology, Staphylococcus aureus/drug effects
Metabolism	31726879	Green synthesis of ZnO nanoparticles with Veronica multifida and their antibiofilm activity.	Dogan SS, Kocabas A	Hum Exp Toxicol	10.1177/0960327119888270	2019	Anti-Bacterial Agents/chemistry/metabolism/pharmacology, Bacteria/drug effects, Bacterial Physiological Phenomena, Biofilms/drug effects, Green Chemistry Technology, Metal Nanoparticles/chemistry, Microbial Sensitivity Tests, Veronica/chemistry, Zinc Oxide/*chemistry/metabolism	Pathogenicity
Pathogenicity	31804978	From bugs to drugs: Combating antimicrobial resistance by discovering novel antibiotics.	Abou Fayad A, Itani D, Miari M, Tanelian A, Iweir S, Matar GM	J Infect Dev Ctries	10.3855/jidc.10108	2018
	31849660	Fusogenic Liposomes Increase the Antimicrobial Activity of Vancomycin Against Staphylococcus aureus Biofilm.	Scriboni AB, Couto VM, Ribeiro LNM, Freires IA, Groppo FC, de Paula E, Franz-Montan M, Cogo-Muller K	Front Pharmacol	10.3389/fphar.2019.01401	2019
Pathogenicity	31880892	Inhibition of Drug Resistance of Staphylococcus aureus by Efflux Pump Inhibitor and Autolysis Inducer to Strengthen the Antibacterial Activity of beta-lactam Drugs.	Luan W, Liu X, Wang X, An Y, Wang Y, Wang C, Shen K, Xu H, Li S, Liu M, Yu LU	Pol J Microbiol	10.33073/pjm-2019-047	2019	Anti-Bacterial Agents/pharmacology, Bacterial Proteins/antagonists & inhibitors/genetics/metabolism, Bacteriolysis/drug effects, Cloxacillin/pharmacology, Drug Resistance, Bacterial, Drug Therapy, Combination, Humans, Membrane Transport Proteins/genetics/metabolism, Miconazole/pharmacology, Microbial Sensitivity Tests, Staphylococcal Infections/drug therapy/microbiology, Staphylococcus aureus/cytology/drug effects/genetics/metabolism, Thioridazine/pharmacology, beta-Lactams/pharmacology	Metabolism
	31915570	A new p-terphenyl derivative from the insect-derived fungus Aspergillus candidus Bdf-2 and the synergistic effects of terphenyllin.	Shan T, Wang Y, Wang S, Xie Y, Cui Z, Wu C, Sun J, Wang J, Mao Z	PeerJ	10.7717/peerj.8221	2020
	31916426	Evaluation of Cumulative and Conditional Antibiotic Release from Vancomycin-Embedded Fibrin Sealant and Its Antibacterial Activity : An In Vitro Study.	Shin DW, Sohn MJ, Cho CR, Koo HW, Yoon SW	J Korean Neurosurg Soc	10.3340/jkns.2019.0161	2019
	32002605	The roles of genes associated with regulation, transportation, and macrocyclization in desotamide biosynthesis in Streptomyces scopuliridis SCSIO ZJ46.	Ding W, Dong Y, Ju J, Li Q	Appl Microbiol Biotechnol	10.1007/s00253-020-10414-4	2020	Bacterial Proteins/genetics, Biosynthetic Pathways, Gene Expression Regulation, Bacterial, Genes, Regulator, Multigene Family, Peptides, Cyclic/biosynthesis, Streptomyces/genetics
	32041117	Dibasic Derivatives of Phenylcarbamic Acid as Prospective Antibacterial Agents Interacting with Cytoplasmic Membrane.	Pospisilova S, Malik I, Bezouskova K, Kauerova T, Kollar P, Csollei J, Oravec M, Cizek A, Jampilek J	Antibiotics (Basel)	10.3390/antibiotics9020064	2020
Pathogenicity	32068948	Design, Synthesis, and Dual Evaluation of Quinoline and Quinolinium Iodide Salt Derivatives as Potential Anticancer and Antibacterial Agents.	Jin G, Xiao F, Li Z, Qi X, Zhao L, Sun X	ChemMedChem	10.1002/cmdc.202000002	2020	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antineoplastic Agents/chemical synthesis/chemistry/pharmacology, Cell Line, Cell Proliferation/drug effects, Drug Design, Drug Screening Assays, Antitumor, Escherichia coli/drug effects, Humans, Iodides/chemical synthesis/chemistry/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Quinolines/chemical synthesis/chemistry/pharmacology, Quinolinium Compounds/chemical synthesis/chemistry/pharmacology, Salts/chemical synthesis/chemistry/pharmacology, Staphylococcus aureus/drug effects
Metabolism	32095985	Synthesis of naphthalimide derivatives with potential anticancer activity, their comparative ds- and G-quadruplex-DNA binding studies and related biological activities.	Yildiz U, Kandemir I, Comert F, Akkoc S, Coban B	Mol Biol Rep	10.1007/s11033-019-05239-y	2020	Anti-Bacterial Agents/chemical synthesis/metabolism/pharmacology, Antineoplastic Agents/chemical synthesis/metabolism/pharmacology, Cell Line, Cell Line, Tumor, Cell Survival/drug effects, Circular Dichroism, DNA/chemistry/metabolism, Escherichia coli/drug effects, G-Quadruplexes, Hep G2 Cells, Humans, MCF-7 Cells, Microbial Sensitivity Tests, Models, Chemical, Molecular Structure, Naphthalimides/chemical synthesis/metabolism/pharmacology, Neoplasms/*metabolism/pathology, Structure-Activity Relationship	Pathogenicity
Pathogenicity	32101782	Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017.	Pan F, El-Kashef DH, Kalscheuer R, Muller WEG, Lee J, Feldbrugge M, Mandi A, Kurtan T, Liu Z, Wu W, Proksch P	Eur J Med Chem	10.1016/j.ejmech.2020.112159	2020	Acinetobacter baumannii/drug effects, Animals, Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antifungal Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology, Cell Line, Tumor, Cell Proliferation/drug effects, Cladosporium/chemistry, Density Functional Theory, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Enterococcus faecalis/drug effects, Mice, Microbial Sensitivity Tests, Molecular Structure, Mycobacterium tuberculosis/drug effects, Polyketides/chemistry/isolation & purification/*pharmacology, Pseudomonas aeruginosa/drug effects, Saccharomyces cerevisiae/drug effects, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Ustilago/drug effects	Enzymology
Pathogenicity	32146452	Chemical composition and antibacterial activity of essential oils against pathogens often related to cattle endometritis.	Braga Paiano R, Bonilla J, Moro de Sousa RL, Micke Moreno A, Sampaio Baruselli P	J Infect Dev Ctries	10.3855/jidc.12076	2020	Actinomycetaceae/drug effects, Animals, Anti-Infective Agents/pharmacology, Bacterial Infections/drug therapy/veterinary, Cattle, Cattle Diseases/drug therapy/microbiology, Endometritis/drug therapy/microbiology/veterinary, Escherichia coli/drug effects, Female, Fusobacterium necrophorum/drug effects, Gas Chromatography-Mass Spectrometry, Oils, Volatile/chemistry/*pharmacology, Staphylococcus aureus/drug effects
Pathogenicity	32213553	Identification of ica-dependent biofilm production by Staphylococcus aureus clinical isolates and antibiofilm effects of ascorbic acid against biofilm production.	Kirmusaoglu S, Kasikci H	J Clin Pathol	10.1136/jclinpath-2019-206280	2020	Anti-Bacterial Agents/pharmacology, Ascorbic Acid/pharmacology, Bacterial Proteins/genetics/metabolism, Biofilms/drug effects/growth & development, Microbial Sensitivity Tests, Staphylococcus aureus/*drug effects/physiology	Biotechnology
Enzymology	32220164	Antimicrobial activity of endophytic fungi from the medicinal plants Mammea americana (Calophyllaceae) and Moringa oleifera (Moringaceae)	Mosquera WG, Criado LY, Guerra BE	Biomedica	10.7705/biomedica.4644	2020	Animals, Anti-Bacterial Agents/isolation & purification/pharmacology, Chlorocebus aethiops, Cladosporium/chemistry/isolation & purification/physiology, Drug Evaluation, Preclinical, Drug Resistance, Multiple, Bacterial, Endophytes/isolation & purification/physiology, Escherichia coli/drug effects, Ethanol, Fungi/isolation & purification/physiology, Mammea/microbiology, Microbial Sensitivity Tests, Moringa oleifera/microbiology, Penicillium/chemistry/isolation & purification/physiology, Plant Leaves/microbiology, Plant Stems/microbiology, Plants, Medicinal/microbiology, Seeds/microbiology, Staphylococcus aureus/drug effects, Vero Cells	Phylogeny
Enzymology	32238320	Antifungal polyketide derivatives from the endophytic fungus Aplosporella javeedii.	Gao Y, Wang L, Kalscheuer R, Liu Z, Proksch P	Bioorg Med Chem	10.1016/j.bmc.2020.115456	2020	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antifungal Agents/chemistry/isolation & purification/pharmacology, Ascomycota/chemistry, Candida albicans/drug effects, Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Polyketides/chemistry/isolation & purification/pharmacology, Staphylococcus aureus/drug effects, Structure-Activity Relationship	Phylogeny
Pathogenicity	32299019	Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents.	Jin G, Li Z, Xiao F, Qi X, Sun X	Bioorg Chem	10.1016/j.bioorg.2020.103837	2020	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Antineoplastic Agents/chemical synthesis/chemistry/pharmacology, Cell Line, Cell Proliferation/drug effects, Cell Survival/drug effects, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Escherichia coli/drug effects, Humans, Microbial Sensitivity Tests, Molecular Structure, Quinolines/chemical synthesis/chemistry/pharmacology, Staphylococcus aureus/drug effects, Structure-Activity Relationship
Pathogenicity	32304431	High Fluence Increases the Antibacterial Efficacy of PACK Cross-Linking.	Kling S, Hufschmid FS, Torres-Netto EA, Randleman JB, Willcox M, Zbinden R, Hafezi F	Cornea	10.1097/ICO.0000000000002335	2020	Anti-Bacterial Agents/therapeutic use, Bacteria/drug effects/isolation & purification, Collagen/pharmacology, Cross-Linking Reagents/pharmacology, Eye Infections, Bacterial/diagnosis/drug therapy, Humans, Keratitis/diagnosis/drug therapy, Photochemotherapy/methods, *Visual Acuity	Enzymology
	32308717	Antimicrobial Evaluation of Latex and TLC Fractions from the Leaves of Aloe adigratana Reynolds.	Asmerom D, Hailu GS, Yimer EM, Bitew H, Kahsay G	Evid Based Complement Alternat Med	10.1155/2020/8312471	2020
	32328290	Determination of Antimicrobial and Toxic Metal Removal Activities of Plant-Based Synthesized (Capsicum annuum L. Leaves), Ecofriendly, Gold Nanomaterials.	Baran MF, Acay H, Keskin C	Glob Chall	10.1002/gch2.201900104	2020
Pathogenicity	32342800	Development and Characterization of Polymeric Peptides for Antibody Tagging of Bacterial Targets.	Climacosa FMM, King RAN, Santos BMM, Caoili SEC	Protein Pept Lett	10.2174/0929866527666200427212940	2020	Antibody-Dependent Cell Cytotoxicity, Escherichia coli/chemistry/immunology, Female, Humans, Neutrophils/immunology, Peptides/chemistry/immunology, Staphylococcus aureus/chemistry/immunology, Trinitrobenzenesulfonic Acid/chemistry/immunology
Metabolism	32415637	A eukaryotic expression strategy for producing the novel antimicrobial peptide PRW4.	Zhan N, Wang T, Zhang L, Shan A	Braz J Microbiol	10.1007/s42770-020-00291-4	2020	Animals, Anti-Bacterial Agents/isolation & purification/metabolism/pharmacology, Antimicrobial Cationic Peptides/genetics/isolation & purification/metabolism/pharmacology, Bacteria/drug effects, Fermentation, Gene Expression, Plasmids/genetics, Recombinant Proteins/genetics/isolation & purification/metabolism/pharmacology, Saccharomycetales/*genetics/metabolism, Swine	Enzymology
Pathogenicity	32441134	Chemical composition, antimicrobial and cytotoxic activities of essential oils from Schinus polygamus (Cav.) cabrera leaf and bark grown in Egypt.	El-Nashar HAS, Mostafa NM, El-Badry MA, Eldahshan OA, Singab ANB	Nat Prod Res	10.1080/14786419.2020.1765343	2020	Anacardiaceae, Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Caco-2 Cells, Egypt, Humans, Microbial Sensitivity Tests, *Oils, Volatile/pharmacology, Plant Bark, Plant Leaves
	32454607	Antibacterial, Antitubercular and Antiviral Activity Evaluations of Some Arylidenehydrazide Derivatives Bearing Imidazo[2,1-b]thiazole Moiety.	Ulusoy Guzeldemirci N, Karaman B, Kucukbasmaci O	Turk J Pharm Sci	10.4274/tjps.25743	2017
	32454665	Structure Elucidation and Antimicrobial Activities of Secondary Metabolites from the Flowery Parts of Verbascum mucronatum Lam.	Kahraman C, Tatli II, Kart D, Ekizoglu M, Akdemir ZS	Turk J Pharm Sci	10.4274/tjps.50479	2018
Pathogenicity	32454720	Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkey.	Heydari H, Saltan Iscan G, Eryilmaz M, Bahadir Acikara O, Yilmaz Sarialtin S, Tekin M, Coban T	Turk J Pharm Sci	10.4274/tjps.galenos.2018.86719	2019
Metabolism	32462243	Biogenic iron-silver nanoparticles inhibit bacterial biofilm formation due to Ag(+) release as determined by a novel phycoerythrin-based assay.	Cusimano MG, Ardizzone F, Nasillo G, Gallo M, Sfriso A, Martino-Chillura D, Schillaci D, Baldi F, Gallo G	Appl Microbiol Biotechnol	10.1007/s00253-020-10686-w	2020	Anti-Bacterial Agents/chemistry/metabolism/pharmacology, Biofilms/drug effects/growth & development, Culture Media/chemistry, Iron/analysis/chemistry/metabolism, Klebsiella oxytoca/metabolism, Metal Nanoparticles/chemistry, Microbial Sensitivity Tests, Phycoerythrin/chemistry, Polysaccharides, Bacterial/chemistry/metabolism, Pseudomonas aeruginosa/drug effects, Silver/*chemistry/metabolism/pharmacology, Staphylococcus aureus/drug effects	Pathogenicity
Pathogenicity	32538401	Activity-directed expansion of a series of antibacterial agents.	Leggott A, Clarke JE, Chow S, Warriner SL, O'Neill AJ, Nelson A	Chem Commun (Camb)	10.1039/d0cc02361b	2020	Anilides/chemical synthesis/chemistry/pharmacology, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Staphylococcus aureus/*drug effects, Structure-Activity Relationship
	32539814	Application of median lethal concentration (LC50) of pathogenic microorganisms and their antigens in vaccine development.	Saganuwan SA	BMC Res Notes	10.1186/s13104-020-05126-x	2020	Animals, Anti-Infective Agents/pharmacology, Antigens, Bacterial, Antigens, Viral, Fishes, Gram-Negative Bacteria/pathogenicity, Gram-Positive Bacteria/pathogenicity, Lethal Dose 50, Mice, Models, Theoretical, RNA Viruses/pathogenicity, Rabbits, Rats, Vaccines/*pharmacology
	32590185	Mutations in the MepRAB efflux system contribute to the in vitro development of tigecycline resistance in Staphylococcus aureus.	Fang R, Sun Y, Dai W, Zheng X, Tian X, Zhang X, Wang C, Cao J, Zhou T	J Glob Antimicrob Resist	10.1016/j.jgar.2020.06.005	2020	Bacterial Proteins/genetics, Methicillin-Resistant Staphylococcus aureus, Mutation, Staphylococcus aureus/genetics, Tigecycline/pharmacology
Pathogenicity	32599931	Synthesis of Iron(II)-N-Heterocyclic Carbene Complexes: Paving the Way for a New Class of Antibiotics.	Vinagreiro CS, Lopes R, Royo B, Da Silva GJ, Pereira MM	Molecules	10.3390/molecules25122917	2020	Anti-Bacterial Agents/chemical synthesis/pharmacology, Electron Spin Resonance Spectroscopy, Escherichia coli/drug effects, Heterocyclic Compounds/chemistry, Hydroxyl Radical/chemistry, Imidazoles/chemistry, Iron/chemistry, Methane/*analogs & derivatives/chemistry, Microbial Sensitivity Tests, Spectrophotometry, Ultraviolet, Staphylococcus aureus/drug effects, Structure-Activity Relationship
	32604791	N-Nonyloxypentyl-l-Deoxynojirimycin Inhibits Growth, Biofilm Formation and Virulence Factors Expression of Staphylococcus aureus.	De Gregorio E, Esposito A, Vollaro A, De Fenza M, D'Alonzo D, Migliaccio A, Iula VD, Zarrilli R, Guaragna A	Antibiotics (Basel)	10.3390/antibiotics9060362	2020
Pathogenicity	32659547	Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents.	Lin S, Chen Y, Li H, Liu J, Liu S	Eur J Med Chem	10.1016/j.ejmech.2020.112596	2020	Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Cell Line, Cell Survival/drug effects, Chalcones/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Drug Design, Humans, Mice, Mice, Inbred C57BL, Microbial Sensitivity Tests, Molecular Structure, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Surface-Active Agents/chemical synthesis/chemistry/*pharmacology
Pathogenicity	32663668	Insight into antimicrobial activity of substituted phenylcarbamoyloxypiperazinylpropanols.	Pospisilova S, Malik I, Curillova J, Michnova H, Cerna L, Padrtova T, Hosek J, Pecher D, Cizek A, Jampilek J	Bioorg Chem	10.1016/j.bioorg.2020.104060	2020	Anti-Infective Agents/pharmacology/therapeutic use, Carbamates/pharmacology/therapeutic use, Humans, Piperazines/pharmacology/*therapeutic use, Structure-Activity Relationship
Phylogeny	32670230	Molecular Mechanisms and Epidemiology of Fosfomycin Resistance in Staphylococcus aureus Isolated From Patients at a Teaching Hospital in China.	Xu W, Chen T, Wang H, Zeng W, Wu Q, Yu K, Xu Y, Zhang X, Zhou T	Front Microbiol	10.3389/fmicb.2020.01290	2020
	32708067	Characterization of Pediococcus acidilactici PFC69 and Lactococcus lactis PFC77 Bacteriocins and Their Antimicrobial Activities in Tarhana Fermentation.	Kaya HI, Simsek O	Microorganisms	10.3390/microorganisms8071083	2020
Phylogeny	32708115	In Vitro Antimicrobial and Antiproliferative Activities of the Root Bark Extract and Isolated Chemical Constituents of Zanthoxylum paracanthum Kokwaro (Rutaceae).	Kaigongi MM, Lukhoba CW, Yaouba S, Makunga NP, Githiomi J, Yenesew A	Plants (Basel)	10.3390/plants9070920	2020
Pathogenicity	32720091	Stability studies with tigecycline in bacterial growth medium and impact of stabilizing agents.	Amann LF, Vicente ER, Rathke M, Broeker A, Riedner M, Wicha SG	Eur J Clin Microbiol Infect Dis	10.1007/s10096-020-03970-0	2020	Anti-Bacterial Agents/pharmacology, Culture Media, Excipients, Humans, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects, Tigecycline/*pharmacology	Cultivation
Enzymology	32745508	Azacoccones F-H, new flavipin-derived alkaloids from an endophytic fungus Epicoccum nigrum MK214079.	Harwoko H, Lee J, Hartmann R, Mandi A, Kurtan T, Muller WEG, Feldbrugge M, Kalscheuer R, Ancheeva E, Daletos G, Frank M, Liu Z, Proksch P	Fitoterapia	10.1016/j.fitote.2020.104698	2020	Alkaloids/isolation & purification/pharmacology, Animals, Anti-Bacterial Agents/isolation & purification/pharmacology, Antifungal Agents/isolation & purification/pharmacology, Antineoplastic Agents/isolation & purification/pharmacology, Ascomycota/chemistry, Basidiomycota, Biological Products/isolation & purification/pharmacology, Cell Line, Tumor, Endophytes/chemistry, Mice, Microbial Sensitivity Tests, Molecular Structure, Plant Leaves/microbiology, Russia, Salix/microbiology, Staphylococcus aureus/drug effects, o-Phthalaldehyde/analogs & derivatives/isolation & purification/pharmacology	Phylogeny
Enzymology	32787074	Development of Highly Potent Carbazole Amphiphiles as Membrane-Targeting Antimicrobials for Treating Gram-Positive Bacterial Infections.	Lin S, Liu J, Li H, Liu Y, Chen Y, Luo J, Liu S	J Med Chem	10.1021/acs.jmedchem.0c00433	2020	Animals, Anti-Bacterial Agents/chemistry/pharmacology, Carbazoles/chemistry/pharmacology, Drug Design, Gram-Positive Bacteria/drug effects/physiology, *Hydrophobic and Hydrophilic Interactions, Kinetics, Mice	Pathogenicity
	32819727	[Antimicrobial effects of fentanyl and bupivacaine].	Kesici S, Demirci M, Kesici U	Braz J Anesthesiol	10.1016/j.bjan.2020.04.010	2020	Anesthetics, Local/administration & dosage/pharmacology, Anti-Infective Agents/administration & dosage/pharmacology, Bupivacaine/administration & dosage/pharmacology, Drug Synergism, Fentanyl/administration & dosage/pharmacology, Hydrochloric Acid/pharmacology, Microbial Sensitivity Tests, Prospective Studies, Sodium Hydroxide/pharmacology
	32834112	Structural basis of quinolone derivatives, inhibition of type I and II topoisomerases and inquiry into the relevance of bioactivity in odd or even branches with molecular docking study.	Wang Y, Xiao F, Jin G	J Mol Struct	10.1016/j.molstruc.2020.128869	2020
	32859056	A Fluorinated Analogue of Marine Bisindole Alkaloid 2,2-Bis(6-bromo-1H-indol-3-yl)ethanamine as Potential Anti-Biofilm Agent and Antibiotic Adjuvant Against Staphylococcus aureus.	Campana R, Mangiaterra G, Tiboni M, Frangipani E, Biavasco F, Lucarini S, Citterio B	Pharmaceuticals (Basel)	10.3390/ph13090210	2020
Pathogenicity	32924637	Type I collagen hydrogels as a delivery matrix for royal jelly derived extracellular vesicles.	Ramirez OJ, Alvarez S, Contreras-Kallens P, Barrera NP, Aguayo S, Schuh CMAP	Drug Deliv	10.1080/10717544.2020.1818880	2020	Cell Movement/drug effects/physiology, Collagen Type I/administration & dosage/chemical synthesis, Dose-Response Relationship, Drug, Drug Delivery Systems/methods, Extracellular Vesicles/chemistry, Fatty Acids/administration & dosage/chemical synthesis, Fibroblasts/drug effects/physiology, Humans, Hydrogels/*administration & dosage/chemical synthesis
Biotechnology	32945189	Production of 3-desmethyl protostreptovaricin I from the genetically engineered Streptomyces spectabilis CCTCC M2017417.	Liu Y, Cui X, Li Z, Chen X, Zeng G, Sun Y	J Asian Nat Prod Res	10.1080/10286020.2020.1816976	2020	Anti-Bacterial Agents/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Streptomyces, Streptovaricin
Biotechnology	33006856	Antibacterial effects of hydrogen peroxide and caprylic acid on selected foodborne bacteria.	Vyrostkova J, Pipova M, Semjon B, Jevinova P, Regecova I, Malova J	Pol J Vet Sci	10.24425/pjvs.2020.134689	2020	Animals, Bacteria/drug effects, Caprylates/administration & dosage/pharmacology, Cheese, Disinfectants/pharmacology, Dose-Response Relationship, Drug, Food Microbiology, Hydrogen Peroxide/administration & dosage/pharmacology, Meat/microbiology, Poultry, Rabbits, Sheep, *Water Microbiology	Pathogenicity
Pathogenicity	33074530	Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies.	Cavalluzzi MM, Budriesi R, De Salvia MA, Quintieri L, Piarulli M, Milani G, Gualdani R, Micucci M, Corazza I, Rosato A, Viale M, Caputo L, Franchini C, Lentini G	Pharmacol Rep	10.1007/s43440-020-00167-2	2020	Animals, Anti-Bacterial Agents/pharmacology, Antidiarrheals/therapeutic use, Bacteria/drug effects, Colon/physiopathology, Diarrhea/drug therapy/microbiology/physiopathology, Dose-Response Relationship, Drug, Gram-Negative Bacterial Infections/drug therapy/microbiology, Gram-Positive Bacterial Infections/drug therapy/microbiology, Guinea Pigs, Ileum/physiopathology, Loperamide/therapeutic use, Male, Microbial Sensitivity Tests, Muscle Contraction/drug effects, Neuroprotective Agents/therapeutic use, Piperidines/therapeutic use, Quaternary Ammonium Compounds/therapeutic use, Rats, Rats, Sprague-Dawley, Thiazoles/therapeutic use
	33134136	Antibacterial oral sprays from kaffir lime (Citrus hystrix DC.) fruit peel oil and leaf oil and their activities against respiratory tract pathogens.	Srifuengfung S, Bunyapraphatsara N, Satitpatipan V, Tribuddharat C, Junyaprasert VB, Tungrugsasut W, Srisukh V	J Tradit Complement Med	10.1016/j.jtcme.2019.09.003	2019
Pathogenicity	33137559	Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker.	Zhang GY, Zhang Z, Li K, Liu J, Li B, Jin Z, Liu YH, Tang YZ	Bioorg Chem	10.1016/j.bioorg.2020.104398	2020	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Cytochrome P-450 Enzyme Inhibitors/chemical synthesis/chemistry/pharmacology, Cytochrome P-450 Enzyme System/metabolism, Diterpenes/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Drug Design, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Microsomes, Liver/drug effects/enzymology, Molecular Structure, Piperazine/chemistry/pharmacology, Polycyclic Compounds/chemical synthesis/chemistry/*pharmacology, Structure-Activity Relationship, Triazoles/chemistry/pharmacology	Metabolism
Pathogenicity	33190958	Synthesis and evaluation of new quinazoline-benzimidazole hybrids as potent anti-microbial agents against multidrug resistant Staphylococcus aureus and Mycobacterium tuberculosis.	Malasala S, Ahmad MN, Akunuri R, Shukla M, Kaul G, Dasgupta A, Madhavi YV, Chopra S, Nanduri S	Eur J Med Chem	10.1016/j.ejmech.2020.112996	2020	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Benzimidazoles/chemistry/pharmacology, Dose-Response Relationship, Drug, Microbial Sensitivity Tests, Molecular Structure, Mycobacterium tuberculosis/drug effects, Quinazolines/chemistry/pharmacology, Staphylococcus aureus/*drug effects, Structure-Activity Relationship
Pathogenicity	33203170	Enhancing Drug Efficacy against Mastitis Pathogens-An In Vitro Pilot Study in Staphylococcus aureus and Staphylococcus epidermidis.	Rajamanickam K, Yang J, Chidambaram SB, Sakharkar MK	Animals (Basel)	10.3390/ani10112117	2020
Pathogenicity	33296391	Development and validation of a new microplate assay that utilises optical density to quantify the antibacterial activity of honeys including Jarrah, Marri and Manuka.	Green KJ, Dods K, Hammer KA	PLoS One	10.1371/journal.pone.0243246	2020	Anti-Bacterial Agents/analysis/pharmacology, Australia, Bacteria/drug effects, Bacterial Infections/drug therapy, Enterococcus faecalis/drug effects, Escherichia coli/drug effects, Honey/analysis, Humans, Microbial Sensitivity Tests/*methods, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects
	33310491	Through quorum sensing, Pseudomonas aeruginosa resists noble metal-based nanomaterials toxicity.	Li Z, Zhang Y, Huang D, Huang L, Zhang H, Li N, Wang M	Environ Pollut	10.1016/j.envpol.2020.116138	2020	Anti-Bacterial Agents/toxicity, Bacterial Proteins/pharmacology, Biofilms, Metal Nanoparticles/toxicity, Palladium/toxicity, Platinum/toxicity, Pseudomonas aeruginosa, Quorum Sensing
Enzymology	33318621	Structurally diverse polyketides and phenylspirodrimanes from the soft coral-associated fungus Stachybotrys chartarum SCSIO41201.	Yang B, Long J, Pang X, Lin X, Liao S, Wang J, Zhou X, Li Y, Liu Y	J Antibiot (Tokyo)	10.1038/s41429-020-00386-y	2020	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Antineoplastic Agents/chemistry/isolation & purification/pharmacology, Cell Line, Tumor, Humans, Inhibitory Concentration 50, Methicillin-Resistant Staphylococcus aureus/drug effects, Polyketides/chemistry/isolation & purification/pharmacology, Spiro Compounds/chemistry/isolation & purification/pharmacology, Stachybotrys/*metabolism	Phylogeny
Metabolism	33350415	An in vitro selective inhibitory effect of silver(i) aminoacidates against bacteria and intestinal cell lines and elucidation of the mechanism of action by means of DNA binding properties, DNA cleavage and cell cycle arrest.	Rendosova M, Gyepes R, Maruscakova IC, Mudronova D, Sabolova D, Kello M, Vilkova M, Almasi M, Huntosova V, Zemek O, Vargova Z	Dalton Trans	10.1039/d0dt03332d	2020	Animals, Anti-Bacterial Agents/chemistry/metabolism/pharmacology, Cell Line, Tumor, Coordination Complexes/chemistry/metabolism/pharmacology, DNA/metabolism, DNA Cleavage/drug effects, Humans, Intestines/cytology, Silver/chemistry, Swine	Pathogenicity
Pathogenicity	33381566	Evaluation of Antibacterial Activity of Three Quaternary Ammonium Disinfectants on Different Germs Isolated from the Hospital Environment.	Ramzi A, Oumokhtar B, Ez Zoubi Y, Filali Mouatassem T, Benboubker M, El Ouali Lalami A	Biomed Res Int	10.1155/2020/6509740	2020	Acinetobacter baumannii/drug effects, Anti-Bacterial Agents/pharmacology, Biofilms/drug effects, Diffusion, Disinfectants/pharmacology, Enterobacter cloacae/drug effects, Escherichia coli/drug effects, Hospitals, Klebsiella pneumoniae/drug effects, Microbial Sensitivity Tests, Morocco, Prospective Studies, Pseudomonas aeruginosa/drug effects, Quaternary Ammonium Compounds/*pharmacology, Risk, Risk Assessment, Staphylococcus aureus/drug effects	Phylogeny
Pathogenicity	33421270	The sponges Hymeniacidon perlevis and Halichondria panicea are reservoirs of antibiotic-producing bacteria against multi-drug resistant Staphylococcus aureus.	Rodriguez Jimenez A, Dechamps E, Giaux A, Goetghebuer L, Bauwens M, Willenz P, Flahaut S, Laport MS, George IF	J Appl Microbiol	10.1111/jam.14999	2021	Animals, Anti-Bacterial Agents/biosynthesis/pharmacology, Bacteria/metabolism, Methicillin Resistance/drug effects, Methicillin-Resistant Staphylococcus aureus/drug effects, Porifera/*microbiology, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Vancomycin/pharmacology	Metabolism
Metabolism	33486576	Extracellular myco-synthesis of nano-silver using the fermentable yeasts Pichia kudriavzeviiHA-NY2 and Saccharomyces uvarumHA-NY3, and their effective biomedical applications.	Ammar HA, El Aty AAA, El Awdan SA	Bioprocess Biosyst Eng	10.1007/s00449-020-02494-3	2021	Animals, Anti-Inflammatory Agents/chemistry, Bacillus subtilis/metabolism, Candida tropicalis/metabolism, Carrageenan/chemistry, Drug Screening Assays, Antitumor, Fermentation, Fusarium/metabolism, HCT116 Cells, Humans, Indomethacin/pharmacology, Inhibitory Concentration 50, Light, Metal Nanoparticles/chemistry, Microbial Sensitivity Tests, Microscopy, Electron, Transmission, PC-3 Cells, Phylogeny, Pichia/metabolism, Pseudomonas aeruginosa/metabolism, Rats, Rats, Wistar, Saccharomyces/metabolism, Scattering, Radiation, Silver/*chemistry, Spectrophotometry, Ultraviolet, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus/metabolism	Pathogenicity
Enzymology	33492131	Antibacterial Prenylated p-Hydroxybenzoic Acid Derivatives from Oberonia myosurus and Identification of Putative Prenyltransferases.	Ren FC, Liu L, Lv YF, Bai X, Kang QJ, Hu XJ, Zhuang HD, Yang L, Hu JM, Zhou J	J Nat Prod	10.1021/acs.jnatprod.0c01101	2021	Anti-Bacterial Agents/isolation & purification/pharmacology, China, Dimethylallyltranstransferase/genetics, Hydroxybenzoates/isolation & purification/pharmacology, Microbial Sensitivity Tests, Molecular Structure, Orchidaceae/chemistry/enzymology, Phytochemicals/isolation & purification/pharmacology, Prenylation, Staphylococcus/drug effects	Phylogeny
	33535577	Biofunctionalization of Poly(lactide-co-glycolic acid) Using Potent NorA Efflux Pump Inhibitors Immobilized on Nanometric Alpha-Zirconium Phosphate to Reduce Biofilm Formation.	Pica M, Messere N, Felicetti T, Sabatini S, Pietrella D, Nocchetti M	Materials (Basel)	10.3390/ma14030670	2021
Pathogenicity	33608109	Ultrastructural changes in methicillin-resistant Staphylococcus aureus (MRSA) induced by a novel cyclic peptide ASP-1 from Bacillus subtilis: A scanning electron microscopy (SEM) study.	Deshmukh R, Chalasani AG, Chattopadhyay D, Roy U	Rev Argent Microbiol	10.1016/j.ram.2020.11.006	2021	Anti-Bacterial Agents/pharmacology, Bacillus subtilis/chemistry, Methicillin-Resistant Staphylococcus aureus/drug effects/ultrastructure, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Peptides, Cyclic/*pharmacology
Pathogenicity	33616480	Development and characterization of lyophilized cefpodoxime proxetil-Pluronic((R)) F127/polyvinylpyrrolidone K30 solid dispersions with improved dissolution and enhanced antibacterial activity.	Yurtdas-Kirimlioglu G	Pharm Dev Technol	10.1080/10837450.2021.1889584	2021	Anti-Bacterial Agents/administration & dosage/chemistry/pharmacology, Bacteria/drug effects, Capsules, Ceftizoxime/administration & dosage/analogs & derivatives/chemistry/pharmacology, Chemistry, Pharmaceutical/methods, Drug Carriers/chemistry, Drug Liberation, Freeze Drying, Microbial Sensitivity Tests, Particle Size, Poloxamer/chemistry, Povidone/analogs & derivatives/chemistry, Solubility, Wettability
Pathogenicity	33634364	Therapeutic Effects of Newly Synthesized Boron Compounds (BGM and BGD) on Hepatocellular Carcinoma.	Gunduz MK, Bolat M, Kaymak G, Berikten D, Kose DA	Biol Trace Elem Res	10.1007/s12011-021-02647-9	2021	Antioxidants, Boron/pharmacology, Boron Compounds/pharmacology, Carcinoma, Hepatocellular/drug therapy, Glycine, Humans, Liver Neoplasms/drug therapy
	33656844	Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics.	Shchelik IS, Tomio A, Gademann K	ACS Infect Dis	10.1021/acsinfecdis.1c00015	2021	Anti-Bacterial Agents/pharmacology, Microbial Sensitivity Tests, Pseudomonas aeruginosa, Staphylococcus aureus, Vancomycin/pharmacology
Enzymology	33729901	Moringa oleifera leaves: could solvent and extraction method affect phenolic composition and bioactivities?	Bennour N, Mighri H, Bouhamda T, Mabrouk M, Apohan E, Yesilada O, Kucukbay H, Akrout A	Prep Biochem Biotechnol	10.1080/10826068.2021.1891550	2021	Anti-Bacterial Agents/analysis/isolation & purification/pharmacology, Antioxidants/analysis/isolation & purification/pharmacology, Flavonoids/analysis/isolation & purification/pharmacology, Moringa oleifera/chemistry, Phenols/analysis/isolation & purification/pharmacology, Plant Extracts/chemistry/isolation & purification/pharmacology, Plant Leaves/chemistry, Polyphenols/analysis/isolation & purification/pharmacology, Solvents	Phylogeny
	33768737	Design and evaluation of the antimicrobial properties of ackee seed extract silver nanoparticle film formulations.	Odeniyi MA, Olusomoka E, Odeniyi OA, Adebayo-Tayo BC	Polim Med	10.17219/pim/130388	2020	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents/pharmacology, Blighia, *Metal Nanoparticles, Microbial Sensitivity Tests, Pichia, Plant Extracts/pharmacology, Seeds, Silver/pharmacology, Spectroscopy, Fourier Transform Infrared
Pathogenicity	33810440	Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities.	Wajs-Bonikowska A, Malarz J, Szoka L, Kwiatkowski P, Stojakowska A	Molecules	10.3390/molecules26071883	2021	Anti-Bacterial Agents/chemistry/pharmacology, Asteraceae/chemistry, Bacteria/drug effects, Cell Line, Humans, Oils, Volatile/chemistry/pharmacology, Plant Components, Aerial/chemistry, Plant Extracts/chemistry/pharmacology, Plant Oils/chemistry/pharmacology, Plant Roots/*chemistry
	33829050	Efficacy Prediction of Four Pharmaceutical Formulations for Intramammary Administration Containing Aloe vera (L.) Burm. f. Combined With Ceftiofur or Cloxacillin in Lactating Cows as an Alternative Therapy to Treat Mastitis Caused by Staphylococcus aureus.	Forno-Bell N, Munoz MA, Chacon O, Pacha P, Iraguen D, Cornejo J, San Martin B	Front Vet Sci	10.3389/fvets.2021.572568	2021
Pathogenicity	33838179	Effect of sub-lethal doses of nisin on Staphylococcus aureus toxin production and biofilm formation.	Shivaee A, Rajabi S, Farahani HE, Imani Fooladi AA	Toxicon	10.1016/j.toxicon.2021.03.018	2021	Anti-Bacterial Agents/pharmacology, Biofilms, Enterotoxins, Humans, Nisin/pharmacology, Staphylococcal Infections, Staphylococcus aureus	Biotechnology
Pathogenicity	33857737	Design, synthesis and biological evaluation of novel pleuromutilin derivatives as potent anti-MRSA agents targeting the 50S ribosome.	Huang SY, Wang X, Shen DY, Chen F, Zhang GY, Zhang Z, Li K, Jin Z, Du D, Tang YZ	Bioorg Med Chem	10.1016/j.bmc.2021.116138	2021	Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Cell Survival/drug effects, Diterpenes/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Drug Design, Female, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Mice, Inbred ICR, Microbial Sensitivity Tests, Models, Molecular, Molecular Structure, Polycyclic Compounds/chemical synthesis/chemistry/pharmacology, RAW 264.7 Cells, Ribosome Subunits, Large, Bacterial/drug effects, Structure-Activity Relationship
	33903102	Development of a Broth Microdilution Method for Exebacase Susceptibility Testing.	Oh JT, Ambler JE, Cassino C, Schuch R	Antimicrob Agents Chemother	10.1128/AAC.02587-20	2021	Anti-Bacterial Agents/pharmacology, Endopeptidases, Microbial Sensitivity Tests, Staphylococcus aureus
	33910968	Determination of MIC Quality Control Parameters for Exebacase, a Novel Lysin with Antistaphylococcal Activity.	Traczewski MM, Ambler JE, Schuch R	J Clin Microbiol	10.1128/JCM.03117-20	2021	Anti-Bacterial Agents/pharmacology, Endopeptidases, Microbial Sensitivity Tests, Quality Control, Staphylococcus aureus
	33927460	The Antibacterial Properties of 4, 8, 4', 8'-Tetramethoxy (1,1'-biphenanthrene) -2,7,2',7'-Tetrol from Fibrous Roots of Bletilla striata.	Huang XJ, Xiong N, Chen BC, Luo F, Huang M, Ding ZS, Qian CD	Indian J Microbiol	10.1007/s12088-021-00932-8	2021
Phylogeny	34048334	Study of the impact of cultivation conditions and peg surface modification on the in vitro biofilm formation of Staphylococcus aureus and Staphylococcus epidermidis in a system analogous to the Calgary biofilm device.	Diepoltova A, Konecna K, Jandourek O, Nachtigal P	J Med Microbiol	10.1099/jmm.0.001371	2021	Animals, Bacteriological Techniques/instrumentation/methods, Biofilms/classification/drug effects/growth & development, Biomass, Culture Media/chemistry/pharmacology, Extracellular Polymeric Substance Matrix/classification/drug effects, Humans, Species Specificity, Staphylococcus/classification/drug effects/*physiology	Pathogenicity
	34067029	Rhodomyrtone Accumulates in Bacterial Cell Wall and Cell Membrane and Inhibits the Synthesis of Multiple Cellular Macromolecules in Epidemic Methicillin-Resistant Staphylococcus aureus.	Nwabor OF, Leejae S, Voravuthikunchai SP	Antibiotics (Basel)	10.3390/antibiotics10050543	2021
Pathogenicity	34153574	Design, synthesis and biological evaluation of pleuromutilin-Schiff base hybrids as potent anti-MRSA agents in vitro and in vivo.	Li B, Zhang Z, Zhang JF, Liu J, Zuo XY, Chen F, Zhang GY, Fang HQ, Jin Z, Tang YZ	Eur J Med Chem	10.1016/j.ejmech.2021.113624	2021	Animals, Anti-Bacterial Agents/chemical synthesis/pharmacology/therapeutic use, Diterpenes/chemical synthesis/pharmacology/therapeutic use, Drug Design, Female, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Inbred ICR, Microbial Sensitivity Tests, Polycyclic Compounds/chemical synthesis/pharmacology/therapeutic use, Schiff Bases/chemical synthesis/pharmacology/therapeutic use, Staphylococcal Infections/drug therapy
	34228443	Natural Berberine-Hybridized Benzimidazoles as Novel Unique Bactericides against Staphylococcus aureus.	Sun H, Ansari MF, Fang B, Zhou CH	J Agric Food Chem	10.1021/acs.jafc.1c02545	2021	Animals, Anti-Bacterial Agents/pharmacology, Benzimidazoles/pharmacology, Berberine/pharmacology, Microbial Sensitivity Tests, Staphylococcal Infections/drug therapy/veterinary, Staphylococcus aureus
Pathogenicity	34235929	Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn(2+) as Potent Broad-Spectrum Antibacterial Agents with a Membrane-Disruptive Mechanism.	Liu J, Li H, Li H, Fang S, Shi J, Chen Y, Zhong R, Liu S, Lin S	J Med Chem	10.1021/acs.jmedchem.1c00858	2021	Amines/chemistry/pharmacology, Animals, Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Carbazoles/chemistry/pharmacology, Coordination Complexes/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Drug Design, Female, Gram-Negative Bacteria/drug effects, Gram-Positive Bacteria/drug effects, Keratitis/drug therapy, Mice, Mice, Inbred C57BL, Microbial Sensitivity Tests, Molecular Structure, Picolinic Acids/chemistry/pharmacology, Structure-Activity Relationship, Zinc/chemistry/*pharmacology
Biotechnology	34265056	Antimicrobial Effects of Novel H2O2-Ag+ Complex on Membrane Damage to Staphylococcus aureus, Escherichia coli O157:H7, and Salmonella Typhimurium.	Han B, Han X, Ren M, You Y, Zhan J, Huang W	J Food Prot	10.4315/JFP-21-087	2022	Colony Count, Microbial, Disinfectants/pharmacology, Escherichia coli O157, Food Microbiology, Humans, Hydrogen Peroxide/pharmacology, Salmonella typhimurium, Staphylococcus aureus	Pathogenicity
Pathogenicity	34319262	Aloe-Emodin-Mediated Photodynamic Therapy Attenuates Sepsis-Associated Toxins in Selected Gram-Positive Bacteria In Vitro.	Otieno W, Liu C, Ji Y	J Microbiol Biotechnol	10.4014/jmb.2105.05024	2021	Animals, Anthraquinones/pharmacology, Bacterial Toxins/metabolism, Biofilms/drug effects/growth & development, Cell Survival/drug effects, Cytokines/metabolism, Dose-Response Relationship, Drug, Drug Resistance, Bacterial/drug effects, Gram-Positive Bacteria/drug effects/metabolism/pathogenicity, Mice, Microbial Viability/drug effects, Photochemotherapy, RAW 264.7 Cells, Sepsis/*microbiology, Virulence/drug effects	Metabolism
Pathogenicity	34328492	Chalcogenide nanoparticles and organic photosensitizers for synergetic antimicrobial photodynamic therapy.	Garin C, Alejo T, Perez-Laguna V, Prieto M, Mendoza G, Arruebo M, Sebastian V, Rezusta A	J Mater Chem B	10.1039/d1tb00972a	2021	Anti-Bacterial Agents/chemistry/pharmacology, Antifungal Agents/chemistry/pharmacology, Candida albicans/drug effects, Cell Survival/drug effects, Copper/chemistry/pharmacology, Fibroblasts/drug effects, Humans, Indocyanine Green/chemistry/pharmacology, Keratinocytes/drug effects, Microbial Sensitivity Tests, Nanoparticles/chemistry, Particle Size, Photochemotherapy, Photosensitizing Agents/chemistry/pharmacology, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, Sulfides/chemistry/pharmacology
	34358033	Reduced Level of Tear Antimicrobial and Immunomodulatory Proteins as a Possible Reason for Higher Ocular Infections in Diabetic Patients.	Kallo G, Varga AK, Szabo J, Emri M, Tozser J, Csutak A, Csosz E	Pathogens	10.3390/pathogens10070883	2021
	34439536	New Unnatural Gallotannins: A Way toward Green Antioxidants, Antimicrobials and Antibiofilm Agents.	Hricoviniova Z, Mascaretti S, Hricoviniova J, Cizek A, Jampilek J	Antioxidants (Basel)	10.3390/antiox10081288	2021
	34576724	Provisional Use of CLSI-Approved Quality Control Strains for Antimicrobial Susceptibility Testing of Mycoplasma ('Mesomycoplasma') hyorhinis.	Kabisch L, Schink AK, Kehrenberg C, Schwarz S	Microorganisms	10.3390/microorganisms9091829	2021
Pathogenicity	34641512	Design, Synthesis, and Antibacterial Evaluation of Novel Ocotillol Derivatives and Their Synergistic Effects with Conventional Antibiotics.	Zhang D, Cao Y, Wang K, Shi Z, Wang R, Meng Q, Bi Y	Molecules	10.3390/molecules26195969	2021	Anti-Bacterial Agents/chemical synthesis/pharmacology, Chloramphenicol/pharmacology, Drug Design, Drug Synergism, Ginsenosides/*chemistry, Kanamycin/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Molecular Structure, Staphylococcus aureus/drug effects, Structure-Activity Relationship
	34680832	Bacillus amyloliquefaciens-Derived Lipopeptide Biosurfactants Inhibit Biofilm Formation and Expression of Biofilm-Related Genes of Staphylococcus aureus.	Englerova K, Bedlovicova Z, Nemcova R, Kiraly J, Madar M, Hajduckova V, Stykova E, Mucha R, Reiffova K	Antibiotics (Basel)	10.3390/antibiotics10101252	2021
Enzymology	34787427	Penicisteckins A-F, Isochroman-Derived Atropisomeric Dimers from Penicillium steckii HNNU-5B18.	Wu XZ, Huang WJ, Liu W, Mandi A, Zhang Q, Zhang L, Zhang W, Kurtan T, Yuan CS, Zhang C	J Nat Prod	10.1021/acs.jnatprod.1c00787	2021	Anti-Bacterial Agents/chemistry/isolation & purification/pharmacology, Biosynthetic Pathways, Chromans/chemistry/isolation & purification/pharmacology, Penicillium/*metabolism, Staphylococcus aureus/drug effects	Phylogeny
Pathogenicity	34823417	A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking.	Zhang Z, Zhang ZS, Wang X, Xi GL, Jin Z, Tang YZ	J Enzyme Inhib Med Chem	10.1080/14756366.2021.1977931	2021	Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Click Chemistry, Diterpenes/chemical synthesis/chemistry/pharmacology, Dose-Response Relationship, Drug, Methicillin-Resistant Staphylococcus aureus/drug effects, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, Polycyclic Compounds/chemical synthesis/chemistry/pharmacology, Surface Plasmon Resonance
	34875839	Antiadhesive, antibiofilm and dispersion activity of biosurfactants isolated from Bacillus amyloliquefaciens 3/22.	Englerova K, Nemcova R, Bedlovicova Z, Stykova E	Ceska Slov Farm	10.5817/CSF2021-5-172	2021	Anti-Bacterial Agents/pharmacology, *Bacillus amyloliquefaciens, Biofilms, Staphylococcus aureus
Pathogenicity	34884631	Towards Property Profiling: SYNTHESIS and SAR Probing of New Tetracyclic Diazaphenothiazine Analogues.	Empel A, Bak A, Kozik V, Latocha M, Cizek A, Jampilek J, Suwinska K, Sochanik A, Zieba A	Int J Mol Sci	10.3390/ijms222312826	2021	Anti-Bacterial Agents/chemistry/pharmacology, Antineoplastic Agents/chemistry/pharmacology, Heterocyclic Compounds/chemistry, Humans, Microbial Sensitivity Tests, Neoplasms/drug therapy, Phenothiazines/chemistry, Staphylococcus aureus/drug effects, Structure-Activity Relationship, Tumor Cells, Cultured
	34887909	Ecofriendly Synthesis of Silver Nanoparticles Using Ananas comosus Fruit Peels: Anticancer and Antimicrobial Activities.	Baran A, Keskin C, Baran MF, Huseynova I, Khalilov R, Eftekhari A, Irtegun-Kandemir S, Kavak DE	Bioinorg Chem Appl	10.1155/2021/2058149	2021
	34943686	Effect of Essential Oils on Growth Inhibition, Biofilm Formation and Membrane Integrity of Escherichia coli and Staphylococcus aureus.	Martinez A, Manrique-Moreno M, Klaiss-Luna MC, Stashenko E, Zafra G, Ortiz C	Antibiotics (Basel)	10.3390/antibiotics10121474	2021
Pathogenicity	34956387	Comparative Study of Antimicrobial, Anti-Inflammatory, and Antioxidant Activities of Different Parts from Pterocarpus Santalinoides l'Her. Ex. DC (Fabaceae).	Ayena AC, Anani K, Dosseh K, Agbonon A, Gbeassor M	Evid Based Complement Alternat Med	10.1155/2021/8938534	2021
Pathogenicity	35022718	Heterogeneous vancomycin resistance in Staphylococcus aureus does not predict development of vancomycin resistance upon vancomycin pressure.	Gaillard T, Dupieux-Chabert C, Butin M, Dumitrescu O, Naceur O, Bouveyron C, Martra A, Bes M, Tristan A, Vandenesch F, Lina G, Laurent F, Rasigade JP	J Antimicrob Chemother	10.1093/jac/dkab488	2022	Anti-Bacterial Agents/pharmacology/therapeutic use, Humans, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Staphylococcal Infections/drug therapy, Staphylococcus aureus, Vancomycin/pharmacology, Vancomycin Resistance
	35114794	Antiadhesive, antibiofilm and dispersion activity of biosurfactants isolated from Bacillus amyloliquefaciens 3/22.	Englerova K, Nemcova R, Bedlovicova Z, Stykova E	Ceska Slov Farm	10.5817/CSF2021-5-172	2021	Anti-Bacterial Agents/pharmacology, *Bacillus amyloliquefaciens, Biofilms, Staphylococcus aureus
	35145500	RW-BP100-4D, a Promising Antimicrobial Candidate With Broad-Spectrum Bactericidal Activity.	Tong X, Li J, Wei R, Gong L, Ji X, He T, Wang R	Front Microbiol	10.3389/fmicb.2021.815980	2022
	35146890	Natural Occurring Phenolic Derivatives from Mauritia flexuosa (Buriti) Stems and Their Potential Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus (MRSA).	de Oliveira DM, de Oliveira DBC, Nunes YRF, de Almeida Alves TM, Kohlhoff M, Andrade AA, Cota BB	Chem Biodivers	10.1002/cbdv.202100788	2022	Anti-Bacterial Agents/pharmacology, Arecaceae/chemistry, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Staphylococcus aureus
Pathogenicity	35164034	Contribution to the Evaluation of Physicochemical Properties, Total Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Vinegar Commercialized in Morocco.	Kara M, Assouguem A, Fadili ME, Benmessaoud S, Alshawwa SZ, Kamaly OA, Saghrouchni H, Zerhouni AR, Bahhou J	Molecules	10.3390/molecules27030770	2022	Acetic Acid/chemistry, Anti-Infective Agents/chemistry/pharmacology, Antioxidants/chemistry/pharmacology, Aspergillus niger/drug effects, Microbial Sensitivity Tests, Morocco, Phenols/analysis, Principal Component Analysis, Staphylococcus aureus/drug effects
Pathogenicity	35178733	Antibacterial activity and mechanism of essential oils in combination with medium-chain fatty acids against predominant bovine mastitis pathogens.	Rani S, Verma S, Singh H, Ram C	Lett Appl Microbiol	10.1111/lam.13675	2022	Animals, Anti-Bacterial Agents/chemistry/pharmacology, Cattle, Escherichia coli, Fatty Acids/pharmacology, Female, Humans, Mastitis, Bovine/drug therapy/microbiology, Microbial Sensitivity Tests, Oils, Volatile/chemistry/pharmacology
Pathogenicity	35191589	Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of New Thiosemicarbazide-Triazole Hybrid Derivatives of (S)-Naproxen.	Han MI, Ince U, Gunduz MG, Kucukguzel SG	Chem Biodivers	10.1002/cbdv.202100900	2022	Anti-Bacterial Agents/chemistry, Anti-Infective Agents/pharmacology, Antifungal Agents/chemistry, Escherichia coli, Humans, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, Naproxen/pharmacology, Semicarbazides, Spectroscopy, Fourier Transform Infrared, Staphylococcus aureus, Structure-Activity Relationship, Triazoles/chemistry
	35220163	Design, synthesis and antibacterial evaluation of pleuromutilin derivatives.	Wu G, Zhu Z, Li J, Luo X, Zhu W, Liao G, Xia J, Zhang W, Pan W, Li T, Wu S	Bioorg Med Chem	10.1016/j.bmc.2022.116676	2022	Anti-Bacterial Agents/pharmacology, Diterpenes, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Polycyclic Compounds, Staphylococcus aureus, Urea
	35235612	Dual-functional bioactive silk sericin for osteoblast responses and osteomyelitis treatment.	Noosak C, Jantorn P, Meesane J, Voravuthikunchai S, Saeloh D	PLoS One	10.1371/journal.pone.0264795	2022	Animals, Bombyx, Osteoblasts, Osteomyelitis, Plant Extracts, Saline Solution, *Sericins/pharmacology, Silk/chemistry, Staphylococcus aureus
	35268830	Anthraquinones from the Aerial Parts of Rubia cordifolia with Their NO Inhibitory and Antibacterial Activities.	Luo H, Qin W, Zhang H, Ren FC, Fang WT, Kong QH, Yang L, Zhang JM, Fang CW, Hu JM, Liu SJ	Molecules	10.3390/molecules27051730	2022	*Rubia
Pathogenicity	35269342	Loaded n-Hydroxyapatite/SSG 3D Scaffolds as a Drug Delivery System of Nigella sativa Fractions for the Management of Local Antibacterial Infections.	Dalli M, El Guerraf A, Azizi SE, Benataya K, Azghar A, Mi-Kyung J, Maleb A, Bonglee K, Gseyra N	Nanomaterials (Basel)	10.3390/nano12050856	2022
Pathogenicity	35300362	Investigating antimicrobial features and drug interactions of sedoanalgesics in intensive care unit: an experimental study.	Unlu O, Bingul ES, Kesici S, Demirci M	ADMET DMPK	10.5599/admet.1042	2021
Phylogeny	35310564	Isolation and Characterization of Halophilic Kocuria salsicia Strains from Cheese Brine.	Youn HY, Seo KH	Food Sci Anim Resour	10.5851/kosfa.2022.e1	2022
	35353362	The effect of nickel ions on the susceptibility of bacteria to ciprofloxacin and ampicillin.	Pavlic A, Gobin I, Begic G, Tota M, Abram M, Spalj S	Folia Microbiol (Praha)	10.1007/s12223-022-00960-x	2022
Pathogenicity	35419861	Tagetes lucida Cav. essential oil and the mixture of its main compounds are antibacterial and modulate antibiotic resistance in multi-resistant pathogenic bacteria.	Torres-Martinez R, Moreno-Leon A, Garcia-Rodriguez YM, Hernandez-Delgado T, Delgado-Lamas G, Espinosa-Garcia FJ	Lett Appl Microbiol	10.1111/lam.13721	2022
	35430480	Semisynthetic pleuromutilin antimicrobials with therapeutic potential against methicillin-resistant Staphylococcus aureus by targeting 50S ribosomal subunit.	Wang X, Wang R, Zhang ZS, Zhang GY, Jin Z, Shen R, Du D, Tang YZ	Eur J Med Chem	10.1016/j.ejmech.2022.114341	2022	Animals, Anti-Bacterial Agents/chemistry, Diterpenes, Drug Design, *Methicillin-Resistant Staphylococcus aureus, Mice, Microbial Sensitivity Tests, Molecular Docking Simulation, Polycyclic Compounds, Ribosome Subunits, Staphylococcus aureus
	35453199	Comparative Analysis of the Antimicrobial Activity of Essential Oils and Their Formulated Microemulsions against Foodborne Pathogens and Spoilage Bacteria.	Campana R, Tiboni M, Maggi F, Cappellacci L, Cianfaglione K, Morshedloo MR, Frangipani E, Casettari L	Antibiotics (Basel)	10.3390/antibiotics11040447	2022
Biotechnology	35489426	Effects of citronellal on growth and enterotoxins production in Staphylococcus aureus ATCC 29213.	Zhang M, Li H, Agyekumwaa AK, Yu Y, Xiao X	Toxicon	10.1016/j.toxicon.2022.04.016	2022	Acyclic Monoterpenes, Aldehydes, Enterotoxins/analysis, Food Microbiology, Humans, Staphylococcal Infections, Staphylococcus aureus	Pathogenicity
	35520644	New marine-derived indolymethyl pyrazinoquinazoline alkaloids with promising antimicrobial profiles.	Long S, Resende DISP, Palmeira A, Kijjoa A, Silva AMS, Tiritan ME, Pereira-Terra P, Freitas-Silva J, Barreiro S, Silva R, Remiao F, Pinto E, Martins da Costa P, Sousa E, Pinto MMM	RSC Adv	10.1039/d0ra05319h	2020
	35547306	Identification of 4-isopropyl-thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation.	Elagawany M, Hegazy L, Cao F, Donlin MJ, Rath N, Tavis J, Elgendy B	RSC Adv	10.1039/c8ra06297h	2018
Pathogenicity	35566083	In Silico and Experimental Investigation of the Biological Potential of Some Recently Developed Carprofen Derivatives.	Dumitrascu F, Udrea AM, Caira MR, Nuta DC, Limban C, Chifiriuc MC, Popa M, Bleotu C, Hanganu A, Dumitrescu D, Avram S	Molecules	10.3390/molecules27092722	2022	Anti-Bacterial Agents/chemistry/pharmacology, Carbazoles, Escherichia coli, Gram-Negative Bacteria, Gram-Positive Bacteria, HeLa Cells, Humans, Microbial Sensitivity Tests
	35566270	Synthesis and Antibacterial Activity Studies of the Conjugates of Curcumin with closo-Dodecaborate and Cobalt Bis(Dicarbollide) Boron Clusters.	Druzina AA, Grammatikova NE, Zhidkova OB, Nekrasova NA, Dudarova NV, Kosenko ID, Grin MA, Bregadze VI	Molecules	10.3390/molecules27092920	2022	Anti-Bacterial Agents/pharmacology, Azides, Boron, Boron Compounds, Cobalt, Curcumin/pharmacology, Microbial Sensitivity Tests
	35570556	Designing, structural determination, and antibacterial activity of injectable ciprofloxacin-loaded gelatin-sodium carboxymethyl cellulose composite nanogels against Staphylococcus aureus.	Liu J, Song W, Algharib SA, Luo W, Chen W	Curr Drug Deliv	10.2174/1567201819666220513121219	2022
	35571108	Inhibitory Effect of Andrographis paniculata Lactone on Staphylococcus aureus alpha-Hemolysin.	Wang X, Ma Q, Niu X, Liu Z, Kang X, Mao Y, Li N, Wang G	Front Pharmacol	10.3389/fphar.2022.891943	2022
Pathogenicity	35586806	Thymol Reduces agr-Mediated Virulence Factor Phenol-Soluble Modulin Production in Staphylococcus aureus.	Lade H, Chung SH, Lee Y, Kumbhar BV, Joo HS, Kim YG, Yang YH, Kim JS	Biomed Res Int	10.1155/2022/8221622	2022	Bacterial Proteins/genetics/metabolism, Bacterial Toxins, Humans, Molecular Docking Simulation, Quorum Sensing, Staphylococcal Infections/microbiology, Staphylococcus aureus/drug effects/isolation & purification/metabolism/pathogenicity, *Thymol/pharmacology, Virulence Factors/genetics/metabolism	Metabolism
	35594246	Antibiofilm and cytotoxic potential of extracellular biosynthesized gold nanoparticles using actinobacteria Amycolatopsis sp. KMN.	Kabiri F, Aghaei SS, Pourbabaee AA, Soleimani M, Komeili Movahhed T	Prep Biochem Biotechnol	10.1080/10826068.2022.2076244	2022
	35605553	Design, synthesis and biological evaluation of novel pleuromutilin derivatives possessing 4-aminothiophenol linker as promising antibacterial agents.	Chai F, Wang J, Zhou KX, Wang SK, Liu YH, Jin Z, Tang YZ	Bioorg Chem	10.1016/j.bioorg.2022.105859	2022
	35693470	Effect of five decontamination methods on face masks and filtering facepiece respirators contaminated with Staphylococcus aureus and Pseudomonas aeruginosa.	Martinez E, Crevecoeur S, Dams L, Rabecki F, Habraken S, Haubruge E, Daube G	Access Microbiol	10.1099/acmi.0.000342	2022
	35745634	Antistaphylococcal Activities and ADME-Related Properties of Chlorinated Arylcarbamoylnaphthalenylcarbamates.	Gonec T, Pindjakova D, Vrablova L, Strharsky T, Michnova H, Kauerova T, Kollar P, Oravec M, Jendrzejewska I, Cizek A, Jampilek J	Pharmaceuticals (Basel)	10.3390/ph15060715	2022
	35861080	Novel Benzimidazole-Based Compounds as Antimicrobials: Synthesis, Molecular Docking, Molecular Dynamics and in silico ADME Profile Studies.	Yesilcayir E, Celik I, Sen HT, Gurpinar SS, Eryilmaz M, Kilcigil G	Acta Chim Slov	10.17344/acsi.2021.7314	2022	Anti-Bacterial Agents/pharmacology, Anti-Infective Agents, Benzimidazoles/pharmacology, Ligands, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Dynamics Simulation, Structure-Activity Relationship
	35875944	Design, synthesis, biological evaluation and molecular docking studies of novel pleuromutilin derivatives containing nitrogen heterocycle and alkylamine groups.	Wang Q, Liu J, Zhou ZD, Zhou KX, Li F, Zhang QW, Wang SK, Wang W, Jin Z, Tang YZ	J Enzyme Inhib Med Chem	10.1080/14756366.2022.2104267	2022	Animals, Anti-Bacterial Agents/chemistry/pharmacology, Diterpenes/chemistry/pharmacology, Methicillin-Resistant Staphylococcus aureus, Mice, Microbial Sensitivity Tests, Molecular Docking Simulation, Nitrogen/pharmacology, *Polycyclic Compounds/pharmacology, Staphylococcus aureus
	35884185	Antibiofilm Activity of Omega-3 Fatty Acids and Its Influence on the Expression of Biofilm Formation Genes on Staphylococcus aureus.	Spiegel C, Steixner SJM, Coraca-Huber DC	Antibiotics (Basel)	10.3390/antibiotics11070932	2022
Phylogeny	35889190	iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments.	Dos Santos JDN, Joao SA, Martin J, Vicente F, Reyes F, Lage OM	Microorganisms	10.3390/microorganisms10071471	2022
Pathogenicity	35963132	Design, synthesis, and antibacterial activity of derivatives of Tryptophanyl-tRNA synthetase inhibitor indolmycin.	Sun L, Zhang S, Kou S, Yi H, Cui A, Li Z	Eur J Med Chem	10.1016/j.ejmech.2022.114647	2022	Animals, Anti-Bacterial Agents/pharmacology, Bacterial Proteins, Escherichia coli/drug effects, Indoles/pharmacology, Methicillin-Resistant Staphylococcus aureus/drug effects, Mice, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, *Tryptophan-tRNA Ligase/antagonists & inhibitors
	36047617	Effectiveness of mechanical cleaning, antibiotics, and induction heating on eradication of Staphylococcus aureus in mature biofilms.	Pijls BG, Sanders IMJG, Kuijper EJ, Nelissen RGHH	Bone Joint Res	10.1302/2046-3758.119.BJR-2022-0010.R1	2022
Metabolism	36063866	Prenylated notoamide-type alkaloids isolated from the fungus Aspergillus sclerotiorum and their inhibition of NLRP3 inflammasome activation and antibacterial activities.	Meng Q, Guo X, Wu J, Liu D, Gu Y, Huang J, Fan A, Lin W	Phytochemistry	10.1016/j.phytochem.2022.113424	2022	Alkaloids/chemistry, Anti-Bacterial Agents/metabolism/pharmacology, Aspergillus/chemistry, Chromatography, Liquid, Indole Alkaloids/chemistry, Indolizines, Molecular Structure, NLR Family, Pyrin Domain-Containing 3 Protein/metabolism, Spiro Compounds, Tandem Mass Spectrometry	Proteome
Pathogenicity	36088756	Design, synthesis, and biological evaluation of tetrahydroquinoline amphiphiles as membrane-targeting antimicrobials against pathogenic bacteria and fungi.	Liu J, Li H, He Q, Chen K, Chen Y, Zhong R, Li H, Fang S, Liu S, Lin S	Eur J Med Chem	10.1016/j.ejmech.2022.114734	2022	Humans, Mice, Animals, Gram-Negative Bacteria, Gram-Positive Bacteria, Anti-Bacterial Agents/chemistry, Microbial Sensitivity Tests, Anti-Infective Agents, Bacteria, Fungi
	36144586	Determination of Chemical Compounds and Investigation of Biological Properties of Matricaria chamomilla Essential Oils, Honey, and Their Mixture.	Qasem A, Assaggaf H, Montesano D, Khalil Z, Al-Mijalli SH, Baaboua AE, El Omari N, El Menyiy N, Bakrim S, Sheikh RA, Alshahrani MM, Awadh AAA, Zengin G, Bouyahya A, Mrabti HN	Molecules	10.3390/molecules27185850	2022	Anti-Infective Agents/chemistry/pharmacology, Antifungal Agents/pharmacology, Antioxidants/chemistry/pharmacology, Camphor, Carrageenan, Free Radicals, Honey, Hypoglycemic Agents, Lipoxygenases, Matricaria, Microbial Sensitivity Tests, Oils, Volatile/chemistry/pharmacology, Phytochemicals/pharmacology, alpha-Amylases, alpha-Glucosidases, beta Carotene
Pathogenicity	36232947	Study of Biological Activities and ADMET-Related Properties of Salicylanilide-Based Peptidomimetics.	Pindjakova D, Pilarova E, Pauk K, Michnova H, Hosek J, Magar P, Cizek A, Imramovsky A, Jampilek J	Int J Mol Sci	10.3390/ijms231911648	2022	Ampicillin, Anilides, Anti-Bacterial Agents/pharmacology, Benzamides, Humans, Isoniazid, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Mycobacterium tuberculosis, *Peptidomimetics, Salicylanilides/pharmacology, Vancomycin
Phylogeny	36249367	Isolation and Identification of Flavones Responsible for the Antibacterial Activities of Tillandsia bergeri Extracts.	Lo MM, Benfodda Z, Dunyach-Remy C, Benimelis D, Roulard R, Fontaine JX, Mathiron D, Quero A, Molinie R, Meffre P	ACS Omega	10.1021/acsomega.2c04195	2022
	36250857	Dioxane-Linked Novel Bacterial Topoisomerase Inhibitors Exhibit Bactericidal Activity against Planktonic and Biofilm Staphylococcus aureus In Vitro.	Chen A, Dellos-Nolan S, Lu Y, West JS, Wozniak DJ, Mitton-Fry MJ	Microbiol Spectr	10.1128/spectrum.02056-22	2022
	36296701	Gallomyrtucommulones G and H, New Phloroglucinol Glycosides, from Bioactive Fractions of Myrtus communis against Staphylococcus Species.	Guzzo F, Duran AG, Sanna C, Marasco R, Molfetta N, Buommino E, Fiorentino A, D'Abrosca B	Molecules	10.3390/molecules27207109	2022	Myrtus/chemistry, Phloroglucinol/chemistry, Staphylococcus aureus, Staphylococcus, Glycosides/pharmacology/analysis, Microbial Sensitivity Tests, Plant Leaves/chemistry, Phytochemicals/pharmacology/analysis, Anti-Infective Agents/analysis, Anti-Bacterial Agents/chemistry, Plant Extracts/chemistry
	36354995	New Alkylpyridinium Anthraquinone, Isocoumarin, C-Glucosyl Resorcinol Derivative and Prenylated Pyranoxanthones from the Culture of a Marine Sponge-Associated Fungus, Aspergillus stellatus KUFA 2017.	Machado FP, Rodrigues IC, Gales L, Pereira JA, Costa PM, Dethoup T, Mistry S, Silva AMS, Vasconcelos V, Kijjoa A	Mar Drugs	10.3390/md20110672	2022	Animals, Isocoumarins/pharmacology/chemistry, Porifera/chemistry, Fungi/chemistry, Anthraquinones/pharmacology/chemistry, Anti-Bacterial Agents/chemistry, Resorcinols, Microbial Sensitivity Tests
	36373717	Malfilanol C, a new sesquiterpenoid isolated from the deep-sea-derived Aspergillus puniceus A2 fungus.	Niu S, Huang S, Wang J, He J, Chen M, Zhang G, Hong B	Nat Prod Res	10.1080/14786419.2022.2144299	2022
	36420624	Synthesis of new benzimidazole derivatives containing 1,3,4-thiadiazole: their in vitro antimicrobial, in silico molecular docking and molecular dynamic simulations studies.	Acar Cevik U, Isik A, Evren AE, Kapusiz O, Gul UD, Ozkay Y, Kaplancikli ZA	SAR QSAR Environ Res	10.1080/1062936X.2022.2149620	2022	Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Dynamics Simulation, Escherichia coli, Quantitative Structure-Activity Relationship, Anti-Infective Agents/pharmacology, Anti-Bacterial Agents, Thiadiazoles/pharmacology, Benzimidazoles/pharmacology, Candida albicans
	36421291	Sterilization Procedures for Titanium Alloy Surfaces Leads to Higher Expression of Biofilm-Related Staphylococcus aureus Genes.	Spiegel C, Nogler M, Coraca-Huber DC	Antibiotics (Basel)	10.3390/antibiotics11111647	2022
	36429174	Chitosan-Sodium Caseinate Composite Edible Film Incorporated with Probiotic Limosilactobacillus fermentum: Physical Properties, Viability, and Antibacterial Properties.	Wai SN, How YH, Saleena LAK, Degraeve P, Oulahal N, Pui LP	Foods	10.3390/foods11223583	2022
	36440112	Aminated Quinolinequinones as Privileged Scaffolds for Antibacterial Agents: Synthesis, In Vitro Evaluation, and Putative Mode of Action.	Yildirim H, Bayrak N, Yildiz M, Mataraci-Kara E, Korkmaz S, Shilkar D, Jayaprakash V, TuYuN AF	ACS Omega	10.1021/acsomega.2c03193	2022
	36458057	In vitro synergistic interaction between Melaleuca armillaris essential oil and erythromycin against Staphylococcus aureus isolated from dairy cows.	Buldain D, Gortari Castillo L, Buchamer AV, Bandoni A, Marchetti L, Mestorino N	Front Vet Sci	10.3389/fvets.2022.1005616	2022
Pathogenicity	36499402	Design, Synthesis and Antimicrobial Properties of New Tetracyclic Quinobenzothiazine Derivatives.	Kisiel-Nawrot E, Pindjakova D, Latocha M, Bak A, Kozik V, Suwinska K, Sochanik A, Cizek A, Jampilek J, Zieba A	Int J Mol Sci	10.3390/ijms232315078	2022	Humans, Microbial Sensitivity Tests, Methicillin-Resistant Staphylococcus aureus, Chlorides/pharmacology, Anti-Bacterial Agents/chemistry, Mycobacterium
Pathogenicity	36499415	Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections.	Strharsky T, Pindjakova D, Kos J, Vrablova L, Smak P, Michnova H, Gonec T, Hosek J, Oravec M, Jendrzejewska I, Cizek A, Jampilek J	Int J Mol Sci	10.3390/ijms232315090	2022	Humans, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Cinnamates/pharmacology/chemistry, Anti-Bacterial Agents/pharmacology/chemistry, Staphylococcal Infections
Pathogenicity	36500402	In Vitro Influence of ZnO, CrZnO, RuZnO, and BaZnO Nanomaterials on Bacterial Growth.	Abdallah EM, Modwi A, Al-Mijalli SH, Mohammed AE, Idriss H, Omar AS, Afifi M, Al-Farga A, Goh KW, Ming LC	Molecules	10.3390/molecules27238309	2022	Humans, Microbial Sensitivity Tests, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Anti-Bacterial Agents/pharmacology, Escherichia coli, Staphylococcal Infections, Bacteria
	36526037	Assessment of synergistic activity of rhamnolipid and linezolid against methicillin-resistant Staphylococcus aureus in-vitro and in-vivo with Galleria mellonella larvae model.	Kaskatepe B, Ozturk S	Microb Pathog	10.1016/j.micpath.2022.105945	2022

Reference

@id	authors	catalogue	doi/url	title
1123	Curators of the DSMZ	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 2569)	https://www.dsmz.de/collection/catalogue/details/culture/DSM-2569
20215	Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.		10.1099/ijsem.0.004332	List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
36626	Curators of the CIP		https://brclims.pasteur.fr/brcWeb/souche/detail/1/15226
46381	Curators of the CCUG	Culture Collection University of Gothenburg (CCUG) (CCUG 15915)	https://www.ccug.se/strain?id=15915
66792	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770	Curators of the JCM		https://jcm.brc.riken.jp/en/
68375				Automatically annotated from API ID32STA
69479	João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.		https://microbeatlas.org/	MicrobeAtlas 1.0 beta
69480	Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann		https://diaspora-project.de/progress.html#genomes	Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
69481	Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch		10.21203/rs.3.rs-2527258/v1	Predictions based on the model GenomeNet Sporulation v. 1
83592	Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.		10.60712/SI-ID4996.1	StrainInfo: A central database for resolving microbial strain identifiers
116609	Curators of the CIP	Collection of Institut Pasteur (CIP 103429)	https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20103429

General

NCBI tax id

strain history

Name and taxonomic classification

LPSN

synonyms

Morphology

cell morphology

colony morphology

Culture and growth conditions

culture medium

culture temp

Physiology and metabolism

oxygen tolerance

antibiogram

spore formation

observation

metabolite utilization

antibiotic resistance

metabolite production

metabolite tests

enzymes

fatty acid profile

fatty acids

API ID32STA

Isolation, sampling and environmental information

isolation

isolation source categories

taxonmaps

Safety information

risk assessment

Sequence information

16S sequences

Genome sequences

Genome-based predictions

predictions

External links

straininfo link

literature

Reference