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Strain identifier

BacDive ID: 14445

Type strain: No

Species: Staphylococcus aureus

Strain Designation: 209 P

Strain history: IAM 12082 <-- IID 671 (strain 209P).

NCBI tax ID(s): 1280 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 139

BacDive-ID: 14445

DSM-Number: 346

keywords: genome sequence, 16S sequence, Bacteria, mesophilic, antibiotic resistance, human pathogen

description: Staphylococcus aureus 209 P is a mesophilic human pathogen that has multiple antibiotic resistances.

NCBI tax id

  • NCBI tax id: 1280
  • Matching level: species

strain history

doi: 10.13145/bacdive14445.20221219.7.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Bacilli
  • order: Caryophanales
  • family: Staphylococcaceae
  • genus: Staphylococcus
  • species: Staphylococcus aureus
  • full scientific name: Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)
  • synonyms

    • @ref: 20215
    • synonym: Staphylococcus aureus subsp. anaerobius

@ref: 139

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Bacillales

family: Staphylococcaceae

genus: Staphylococcus

species: Staphylococcus aureus

full scientific name: Staphylococcus aureus Rosenbach 1884

strain designation: 209 P

type strain: no

Morphology

cell morphology

  • @ref: 69480
  • gram stain: positive
  • confidence: 91.433

colony morphology

  • @ref: 139
  • type of hemolysis: beta
  • incubation period: 1-2 days

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
139COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)yeshttps://mediadive.dsmz.de/medium/693Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base
139TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92)yeshttps://mediadive.dsmz.de/medium/92Name: TRYPTICASE SOY YEAST EXTRACT MEDIUM (DSMZ Medium 92) Composition: Trypticase soy broth 30.0 g/l Agar 15.0 g/l Yeast extract 3.0 g/l Distilled water
41865MEDIUM 3 - Columbia agaryesColumbia agar (39.000 g);distilled water (1000.000 ml)

culture temp

@refgrowthtypetemperaturerange
139positivegrowth37mesophilic
41865positivegrowth37mesophilic
67770positivegrowth37mesophilic

Physiology and metabolism

antibiogram

@refmediumPenicillin Goxacillinampicillinticarcillinmezlocillincefalotincefazolincefotaximeaztreonamimipenemtetracyclinechloramphenicolgentamycinamikacinvancomycinerythromycinlincomycinofloxacinnorfloxacincolistinpipemidic acidnitrofurantoinbacitracinpolymyxin bkanamycinneomycindoxycyclineceftriaxoneclindamycinfosfomycinmoxifloxacinlinezolidnystatinquinupristin/dalfopristinteicoplaninpiperacillin/tazobactamincubation temperatureincubation timeoxygen condition
139Mueller-Hinton Agar4032-3436-3842-443440402805032-343022242030302822-240824188262034283836-3832300302032-34
139Mueller-Hinton Agar40-423438-4042-4432-3440-424030050343026282032303024-2601024-2618-20828-30243628-3038-4030-323232028-302032-34
139Mueller-Hinton Agar4434-364046364442-443405036-383026-28282032-34303026010261810302438304038-4034-36400322036371aerob
139Mueller-Hinton Agar42-443640483644423005038322626-28203230-323024-260102620828-302238-40304038-4034400302038371aerob
139Mueller-Hinton Agar28242432222826-2818-200381816-181620141818181800181200018n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.37
139Mueller-Hinton Agar40-423436-3842-443240402805032-3430-3226262030-3228-3028240122418-2010342236n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.37
139Mueller-Hinton Agar423438-4042-4432-3440-4238-40280463230-32242420-2230-3228-3028-3024-260102416-1810282234-36n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.n.d.37
139Mueller Hinton42-4436404834-3642-44402805036-3832262620-22323030260826208302238-40304040-423638030203637aerob

spore formation

  • @ref: 69480
  • spore formation: no
  • confidence: 95.253

halophily

  • @ref: 69480
  • halophily level: halophilic
  • confidence: 98.433

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
6837522599arabinose-fermentation
6837532528turanose-fermentation
6837559640N-acetylglucosamine+fermentation
6837517992sucrose+fermentation
6837517632nitrate+reduction
6837517057cellobiose-fermentation
6837516634raffinose-fermentation
6837516899D-mannitol+fermentation
6837527082trehalose+fermentation
6837517306maltose+fermentation
6837516024D-mannose+fermentation
6837515824D-fructose+fermentation
6837517634D-glucose+fermentation
683754853esculin-hydrolysis
6837518257ornithine-degradation
6837529016arginine+hydrolysis
6837516199urea+hydrolysis

metabolite production

  • @ref: 68375
  • Chebi-ID: 15688
  • metabolite: acetoin
  • production: yes

metabolite tests

  • @ref: 68375
  • Chebi-ID: 15688
  • metabolite: acetoin
  • voges-proskauer-test: +

enzymes

@refvalueactivityec
139catalase+1.11.1.6
139cytochrome-c oxidase-1.9.3.1
68375beta-glucuronidase-3.2.1.31
68375alkaline phosphatase+3.1.3.1
68375L-arginine arylamidase-
68375beta-galactosidase-3.2.1.23
68375beta-glucosidase-3.2.1.21
68375ornithine decarboxylase-4.1.1.17
68375arginine dihydrolase+3.5.3.6
68375urease+3.5.1.5

API ID32STA

@refUREADH ArgODCESCGLUFRUMNEMALLACTREMANRAFRIBCELNITVPbeta GALArgAPALPyrANOVOSACNAGTURARAbeta GUR
139++--+++++++---++--+++/-++---
139++--+++++++-+/--++--+++/-++---
139++--+++++++-+-++--+++++---
139++--+++++++-+-++--+++++---
139++--+++++/-++-+/--++--++-++---
139++--+++++++-+-++--+++++---
139++--+++++++-+/--++--+++++---
139++--+++++++-+-++--+-+++---
139++--+++++++-+-++--+++++---

Isolation, sampling and environmental information

taxonmaps

  • @ref: 69479
  • File name: preview.99_3.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_3;96_3;97_3;98_3;99_3&stattab=map
  • Last taxonomy: Staphylococcus
  • 16S sequence: AB598746
  • Sequence Identity:
  • Total samples: 23199
  • soil counts: 353
  • aquatic counts: 991
  • animal counts: 21663
  • plant counts: 192

Safety information

risk assessment

  • @ref: 139
  • pathogenicity human: yes
  • pathogenicity animal: yes
  • biosafety level: 2
  • biosafety level comment: Risk group (German classification)

Sequence information

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
67770Staphylococcus aureus JCM 2151 gene for 16S rRNA, partial sequenceAB5987461474ena1280
67770Staphylococcus aureus NBRC 12732 gene for 16S rRNA, partial sequenceAB6803361477ena1280

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Staphylococcus aureus NCTC7447GCA_900457305contigncbi1280
66792Staphylococcus aureus subsp. aureus JCM 2151 JCM 2151GCA_001312225contigncbi1295139
66792Staphylococcus aureus strain NCTC74471280.18033wgspatric1280
66792Staphylococcus aureus subsp. aureus JCM 21511295139.3wgspatric1295139
66792Staphylococcus aureus aureus JCM 21512728369715draftimg1295139

External links

@ref: 139

culture collection no.: CCUG 1828, CCM 2022, DSM 346, ATCC 6538P, CIP 53.156, NCTC 7447, WDCM 00033, JCM 2151, BCRC 10451, CECT 240, CGMCC 1.2910, FDA 209P, IAM 1011, IAM 12082, IFO 12732, IID 671, KCTC 1927, LMG 8195, NBRC 12732, NCFB 1963, NCIMB 8625, NRIC 1136, NRRL B-313, RIMD 3109007

straininfo link

@refpassport
20218http://www.straininfo.net/strains/21783
20218http://www.straininfo.net/strains/21773
20218http://www.straininfo.net/strains/228878
20218http://www.straininfo.net/strains/21794
20218http://www.straininfo.net/strains/866263

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Pathogenicity485130New rapid assay for nafcillin in serum by spectrofluorometry.Lichtenwalner DM, Suh B, Lorber B, Sugar AMAntimicrob Agents Chemother10.1128/AAC.16.2.2101979Biological Assay, Humans, Nafcillin/*blood, Spectrometry, Fluorescence/methods
Pathogenicity578459Biological properties and clinical application of propolis. III. Investigation of the sensitivity of Staphylococci isolated from pathological cases to ethanol extract of propolis (EEP). Attempts on inducing resistance in laboratory Staphylococcus strain to EEP.Scheller S, Tustanowski J, Kurylo B, Paradowski Z, Obuszko ZArzneimittelforschung1977Anti-Bacterial Agents/*pharmacology, *Bees, Culture Media, Drug Resistance, Microbial, Humans, Resins, Plant/*pharmacology, Staphylococcal Infections/microbiology, Staphylococcus/*drug effects/isolation & purification, Time FactorsCultivation
Pathogenicity761993Prevention of penicillin-induced lysis of Staphylococcus aureus by cellular lipoteichoic acid.Suginaka H, Shimatani M, Ogawa M, Kotani SJ Antibiot (Tokyo)10.7164/antibiotics.32.731979Bacteriolysis/drug effects, Penicillin G/*antagonists & inhibitors/pharmacology, Staphylococcus aureus/*drug effects/growth & development, Teichoic Acids/*pharmacology, Time Factors
Metabolism884150Studies on bacterial cell wall inhibitors. III. 3-amino-3-deoxy-D-glucose, an inhibitor of bacterial cell wall synthesis.Iwai Y, Tanaka H, Oiwa R, Shimizu S, Omura SBiochim Biophys Acta10.1016/0304-4165(77)90102-71977Alanine/metabolism, Bacterial Proteins/biosynthesis, Cell Wall/drug effects/*physiology, DNA, Bacterial/biosynthesis, Glucosamine/*pharmacology, Kanamycin/pharmacology, Kinetics, Leucine/metabolism, Peptidoglycan/biosynthesis, RNA, Bacterial/biosynthesis, Species Specificity, Staphylococcus aureus/drug effects/*physiology, Thymidine/metabolism, Uridine/metabolismPathogenicity
Phylogeny931810Identification of producer and biological activities of new antibiotics, mimosamycin and chlorocarcins.Mikami Y, Yokoyama K, Omi A, Arai TJ Antibiot (Tokyo)10.7164/antibiotics.29.4081976Animals, *Anti-Bacterial Agents/biosynthesis/pharmacology/therapeutic use, Antibiotics, Antineoplastic/*isolation & purification/therapeutic use, Carcinoma, Ehrlich Tumor/drug therapy, Fungi/drug effects, Leukemia L1210/drug therapy, Mice, Streptomyces/classification/*metabolismEnzymology
Metabolism948143Microorganism capable of decomposing N-acetylglucosaminyl ribitol teichoic acid of Staphylococcus aureus.Iwata S, Tochikubo K, Kato K, Hirata T, Kotani S, Yagi KJpn J Microbiol10.1111/j.1348-0421.1976.tb00918.x1976Bacillus/classification/enzymology, Bacteria/classification/*enzymology/growth & development, Cell Wall/metabolism, Cell-Free System, Enzymes/*metabolism, Hydrolysis, *Soil Microbiology, Spores, Bacterial/growth & development, Staphylococcus aureus/*metabolism, Teichoic Acids/*metabolismEnzymology
1083878Structural requirements for arthritogenicity of peptidoglycans from Staphylococcus aureus and Lactobacillus plant arum and analogous synthetic compounds.Kohashi O, Pearson CM, Watanabe Y, Kotani S, Koga TJ Immunol1976Animals, Antigens, Bacterial, Arthritis, Rheumatoid/*etiology/immunology, Cell Wall/immunology, Female, Lactobacillus/*immunology, Mycobacterium/immunology, *Peptidoglycan, Rats, Rats, Inbred Lew, Skin Tests, Staphylococcus aureus/*immunology
1116984Characterization of the lipids of mesosomal vesicles and plasma membranes from Staphylococcus aureus.Beining PR, Huff E, Prescott B, Theodore TSJ Bacteriol10.1128/jb.121.1.137-143.19751975Cardiolipins/analysis, Carotenoids/analysis, Cell Fractionation, Cell Membrane/analysis, Chromatography, DEAE-Cellulose, Chromatography, Thin Layer, Diglycerides/analysis, Fatty Alcohols/analysis, Glycosides/analysis, Lipids/*analysis, Phospholipids/analysis, Protoplasts, Solvents, Staphylococcus/analysis/*ultrastructure, Vitamin K/analysis
1147743Phagocytic properties of exudative microphages from animals with alloxan diabetes and insulin-induced hypoglycemia.Danieluk-Gil IArch Immunol Ther Exp (Warsz)1975Alloxan/administration & dosage, Animals, Blood Glucose/analysis, Diabetes Mellitus, Experimental/*immunology/pathology, Exudates and Transudates/cytology, Hypoglycemia/*immunology/pathology, Injections, Subcutaneous, Insulin/administration & dosage, Liver/ultrastructure, Male, Mice, Pancreas/ultrastructure, Phagocytes/*immunology
Enzymology1180873Immunoadjuvant activities of peptidoglycan subunits from the cell walls of Staphyloccus aureus and Lactobacillus plantarum.Kotani S, Watanabe Y, Shimono T, Kinoshita F, Narita TBiken J1975*Adjuvants, Immunologic, Animals, Antibody Formation, Cell Wall/analysis/*immunology, Guinea Pigs, Hypersensitivity, Delayed, Lactobacillus/analysis/*immunology, Ovalbumin/immunology, Peptidoglycan/analysis/*immunology/isolation & purification, Staphylococcus aureus/analysis/*immunologyPhylogeny
Pathogenicity1293906[Evaluation of phagocytic activity of peripheral blood neutrophils in patients after kidney transplantation treated with cyclosporin and prednisone or with azathioprine with prednisone].Hrycek A, Szoltysik IActa Haematol Pol1992Adolescent, Adult, Azathioprine/pharmacology, Cyclosporine/pharmacology, Female, Humans, Kidney Transplantation/*immunology, Male, Middle Aged, Neutrophils/*drug effects, Phagocytosis/*drug effects, Prednisone/pharmacology, Staphylococcus aureus/drug effects
Cultivation1297243[The effect of culture media on bacteriocin production in various strains of bacteria].Laukova AVet Med (Praha)1992Bacteriocins/*biosynthesis, *Culture Media, Enterococcus/*metabolism, Staphylococcus/*metabolismMetabolism
Phylogeny1367491Expression of penicillin G acylase gene from Bacillus megaterium ATCC 14945 in Escherichia coli and Bacillus subtilis.Kang JH, Hwang Y, Yoo OJJ Biotechnol10.1016/0168-1656(91)90001-c1991Bacillus megaterium/enzymology/*genetics, Bacillus subtilis/genetics, Bacterial Proteins/*biosynthesis/genetics, Cephalosporins/metabolism, Escherichia coli/genetics, Gene Expression Regulation, Enzymologic, Genetic Vectors, Molecular Weight, Penicillin Amidase/*biosynthesis/genetics, Recombinant Fusion Proteins/*biosynthesis, Species Specificity, Substrate SpecificityEnzymology
Enzymology1699048[Determination of the enterotoxigenicity of conditionally pathogenic microorganisms using the method of suppressing the dehydrogenase activity of the UV mutant Staphylococcus aureus 209 P].Kalinina TE, Ternovskaia LN, Andrusenko IT, Kaminskaia VP, Ved'mina EA, Shepelev APLab Delo1990Bacteriological Techniques, Enterobacteriaceae/*pathogenicity, Enterotoxins/*analysisPathogenicity
Pathogenicity1715631[The action of tomicide on macromolecular synthesis in bacterial cells].Butova LG, Blinkova LPZh Mikrobiol Epidemiol Immunobiol1991Anti-Bacterial Agents/*pharmacology, Anti-Infective Agents, Local/*pharmacology, Bacteriocins, DNA, Bacterial/biosynthesis/drug effects, Depression, Chemical, Dose-Response Relationship, Drug, Leucine/drug effects/metabolism, Macromolecular Substances, RNA, Bacterial/biosynthesis/drug effects, Staphylococcus aureus/*drug effects/metabolism, Thymidine/metabolism, Time Factors, Tritium, Uridine/metabolismMetabolism
Pathogenicity1791781[The effect of the antibiotic AL-87 on the amino acid yield from Staphylococcus aureus 209P cells].Snirnov VV, Churkina LN, Kiprianova EA, Pustovalova LIMikrobiol Zh1991Amino Acids/analysis/*drug effects, Anti-Bacterial Agents/*pharmacology, Culture Media/analysis, Dose-Response Relationship, Drug, Pseudomonas, Staphylococcus aureus/chemistry/*drug effectsBiotechnology
Pathogenicity1884976Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A.Sugai M, Ooku K, Akiyama T, Inoue S, Iseda S, Miyake Y, Suginaka HFEMS Microbiol Lett10.1016/0378-1097(91)90586-y1991Bacteriolysis/*drug effects, Coloring Agents/*pharmacology, Penicillin G/*pharmacology, Staphylococcus aureus/*drug effects, Triazines/*pharmacology
Pathogenicity2013242Effects of antibiotics on nonopsonized adherence of Staphylococcus aureus to human polymorphonuclear leukocytes.Kohada A, Miyake Y, Sugai M, Tsuru H, Suginaka HChemotherapy10.1159/0002388321991Aminoglycosides, Anti-Bacterial Agents/*pharmacology, Bacterial Adhesion/*drug effects, Humans, Lactams, Neutrophils/*drug effects/physiology, Phagocytosis, Staphylococcus aureus/*drug effects/physiology
Enzymology2085620[Hydrolysis of a Staphylococcus aureus cell wall peptidoglycan by 209 P lysoamidase].Severin AI, Il'chenko VIa, Kulaev ISBiokhimiia1990Amino Acid Sequence, Carbohydrate Sequence, Cell Wall/enzymology, Chromatography, Liquid, Electrophoresis, Paper, Hydrolysis, Molecular Sequence Data, Peptide Hydrolases/*chemistry, Peptidoglycan/*metabolism, Staphylococcus aureus/*enzymologyGenetics
Pathogenicity2389120The effect of zinc oxide on Staphylococcus aureus and polymorphonuclear cells in a tissue cage model.Sunzel B, Lasek J, Soderberg T, Elmros T, Hallmans G, Holm SScand J Plast Reconstr Surg Hand Surg10.3109/028443190090045171990Animals, Chemotaxis/*drug effects, Diffusion Chambers, Culture, Guinea Pigs, Models, Biological, Neutrophils/*drug effects, Rabbits, Staphylococcus aureus/*drug effects, Zinc/*pharmacology, Zinc Oxide/*pharmacology
Pathogenicity2447280Effects of mucopolysaccharides on penicillin-induced lysis of Staphylococcus aureus.Kiriyama T, Miyake Y, Sugai M, Kobayashi K, Yoshiga K, Takada K, Suginaka HJ Med Microbiol10.1099/00222615-24-4-3251987Bacteriolysis/*drug effects, Chondroitin Sulfates/pharmacology, Dextran Sulfate, Dextrans/pharmacology, Drug Interactions, Glycosaminoglycans/*pharmacology, Heparin/pharmacology, Hyaluronic Acid/pharmacology, Lipopolysaccharides/metabolism, Mitogens/pharmacology, Penicillin G/*pharmacology, Staphylococcus aureus/*drug effects, Teichoic Acids/metabolismMetabolism
Pathogenicity2481139[A stat-method of determining antibiotic concentration in biological fluids].Pasternak NA, Shenderovich VA, Ved'mina EALab Delo1989Anti-Bacterial Agents/*analysis, Body Fluids/*analysis, Humans, Immunodiffusion, Oxidoreductases/antagonists & inhibitors, Staphylococcus aureus/enzymologyEnzymology
Pathogenicity2509599[Production of oxygen free radicals by phagocytes in patients on hemodialysis].Ueda YKansenshogaku Zasshi10.11150/kansenshogakuzasshi1970.63.9971989Adult, Aged, Anti-Bacterial Agents/pharmacology, Female, Free Radicals, Humans, Klebsiella pneumoniae/drug effects, Luminescent Measurements, Male, Middle Aged, Oxygen/*metabolism, Phagocytes/*metabolism, *Renal DialysisMetabolism
Enzymology2515095Purification of a 51 kDa endo-beta-N-acetylglucosaminidase from Staphylococcus aureus.Sugai M, Koike H, Hong YM, Miyake Y, Nogami R, Suginaka HFEMS Microbiol Lett10.1016/0378-1097(89)90209-71989Acetylglucosaminidase/*isolation & purification, Chromatography, High Pressure Liquid, Electrophoresis, Polyacrylamide Gel, Hexosaminidases/*isolation & purification, Isoelectric Point, Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase, Molecular Weight, Staphylococcus aureus/*enzymologyPhylogeny
Pathogenicity2694953Comparison of electronic and viability counting methods for determination of postantibiotic effect of oxacillin on Staphylococcus aureus.Nadler HL, Curby WA, Forgacs P, Rosenberg FAntimicrob Agents Chemother10.1128/AAC.33.12.21551989Bacteriological Techniques, Microbial Sensitivity Tests, Oxacillin/*pharmacology, Staphylococcus aureus/*drug effects
Pathogenicity2775357Aminoglycosides enhance the adherence of Staphylococcus aureus to HeLa cells.Miyake Y, Kohada A, Fujii I, Sugai M, Suginaka HJ Antimicrob Chemother10.1093/jac/23.1.791989Aminoglycosides, Anti-Bacterial Agents/*pharmacology, Bacterial Adhesion/*drug effects, HeLa Cells, Humans, Staphylococcus aureus/*physiology
Enzymology2847648DNA gyrase of Staphylococcus aureus and inhibitory effect of quinolones on its activity.Takahata M, Nishino TAntimicrob Agents Chemother10.1128/AAC.32.8.119219884-Quinolones, Anti-Infective Agents/*pharmacology, DNA Topoisomerases, Type II/analysis/isolation & purification, DNA, Bacterial/analysis, DNA, Superhelical/analysis, Electrophoresis, Agar Gel, Staphylococcus aureus/drug effects/*enzymology, *Topoisomerase II InhibitorsPhylogeny
Pathogenicity3144613[Influence of human albumin on bactericidal or antibacterial activities of cephems and monobactams].Saionji KJpn J Antibiot1988Albumins/*pharmacology, Cephalosporins/*pharmacology, Escherichia coli/*drug effects, Humans, Microbial Sensitivity Tests, Monobactams/*pharmacology, Pseudomonas aeruginosa/*drug effects, Staphylococcus aureus/*drug effects
Pathogenicity3701783Synthesis of delta 3-1-methylene-1-carbacephems.Herdewijn P, Claes PJ, Vanderhaeghe HJ Med Chem10.1021/jm00155a0131986Cephalexin/pharmacology, Cephalosporins/*chemical synthesis/pharmacology, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Staphylococcus aureus/drug effects
Pathogenicity4084017Phagocytic and bactericidal activities of neutrophils in duodenal ulcer patients during cimetidine treatment.Markiewicz K, Kowalska M, Malec P, Denys AArch Immunol Ther Exp (Warsz)1985Adult, Aged, Cimetidine/*therapeutic use, Duodenal Ulcer/blood/*drug therapy, Female, Humans, Kinetics, Male, Middle Aged, Neutrophils/drug effects/immunology/*physiology, Phagocytosis/*drug effects, Staphylococcus aureus/immunologyEnzymology
Enzymology4106221Electron microscopy during release and purification of mesosomal vesicles and protoplast membranes from Staphylococcus aureus.Popkin TJ, Theodore TS, Cole RMJ Bacteriol10.1128/jb.107.3.907-917.19711971Acetates, Cell Membrane, Centrifugation, Density Gradient, Cesium, Chlorides, Deoxyribonucleases, Enzymes, Lead, *Microscopy, Electron, Organoids, Osmosis, Phosphotungstic Acid, Protoplasts/cytology, Ribonucleases, Staining and Labeling, Staphylococcus/*cytology/growth & development, Sucrose, Uranium
Pathogenicity4166078Antibiotic sensitivity of Micrococcus radiodurans.Hawiger J, Jeljaszewicz JAppl Microbiol10.1128/am.15.2.304-306.19671967Anti-Bacterial Agents/*pharmacology, Bacitracin/pharmacology, Chloramphenicol/pharmacology, Dactinomycin/pharmacology, Dihydrostreptomycin Sulfate/pharmacology, Erythromycin/pharmacology, Kanamycin/pharmacology, Micrococcus/*drug effects, Mitomycins/pharmacology, Neomycin/pharmacology, Penicillin G/pharmacology, *Penicillin Resistance, Vancomycin/pharmacology
Enzymology4373433Cellular location of degradative enzymes in Staphylococcus aureus.Nugent KM, Huff E, Cole RM, Theodore TSJ Bacteriol10.1128/jb.120.3.1012-1016.19741974Acid Phosphatase/metabolism, Adenosine Triphosphatases/metabolism, Alkaline Phosphatase/metabolism, Aminohydrolases/metabolism, Cell Fractionation, Cell Membrane/enzymology, Cytoplasm/enzymology, Endonucleases/metabolism, Enzyme Induction, Glucosephosphate Dehydrogenase/metabolism, Hexokinase/metabolism, Microscopy, Electron, Nucleotidases/metabolism, Penicillinase/biosynthesis, Peptide Hydrolases/*isolation & purification/metabolism, Phosphoric Monoester Hydrolases/*isolation & purification, Protoplasts/enzymology, Staphylococcus/*enzymology/ultrastructure, Subcellular Fractions/enzymologyMetabolism
Enzymology4424507Lipoteichoic acid localization in mesosomal vesicles of Staphylococcus aureus.Huff E, Cole RM, Theodore TSJ Bacteriol10.1128/jb.120.1.273-281.19741974Cell Fractionation, Cell Membrane/analysis, Chromatography, Gas, Chromatography, Paper, Fatty Acids/analysis, Glycerol/analysis, Glycerophosphates/analysis, Hydrolysis, Lipids/analysis, Organoids/*analysis, Phosphates/analysis, Protoplasts, Solvents, Staphylococcus/*analysis, Teichoic Acids/analysis/*isolation & purificationPhylogeny
Pathogenicity4670428Four-hour microbiological assay of gentamicin in serum.Warren E, Snyder RJ, Washington JA IIAntimicrob Agents Chemother10.1128/AAC.1.1.461972Biological Assay, Gentamicins/*blood/pharmacology, Staphylococcus/*drug effects, Time Factors
Enzymology4745430Protein and fatty acid composition of mesosomal vesicles and plasma membranes of Staphylococcus aureus.Theodore TS, Panos CJ Bacteriol10.1128/jb.116.2.571-576.19731973Bacterial Proteins/*analysis/isolation & purification, Cell Membrane/*analysis, Chromatography, Gas, Densitometry, Electrophoresis, Polyacrylamide Gel, Fatty Acids/*analysis, Sodium Dodecyl Sulfate, Staphylococcus/*cytologyPhylogeny
Pathogenicity5423366Lysostaphin-induced, osmotically fragile Staphylococcus aureus cells.Huber TW, Schuhardt VTJ Bacteriol10.1128/jb.103.1.116-119.19701970Agar, Anti-Bacterial Agents/*pharmacology, Cell Wall/analysis/drug effects, Culture Media, Hexosamines/analysis, L Forms/drug effects, Lysostaphin/pharmacology, Manometry, *Osmotic Fragility, Oxygen Consumption, Polysaccharides, Bacterial/analysis, Protoplasts/metabolism, Serotyping, Sodium Chloride, Staphylococcus/analysis/*drug effects/growth & development, Time FactorsCultivation
Pathogenicity5647523Differential chromatographic bioassay for the gentamicin complex.Wagman GH, Oden EM, Weinstein MJAppl Microbiol10.1128/am.16.4.624-627.19681968*Biological Assay, Chromatography, Paper, Gentamicins/*analysis/pharmacology, Methods, Staphylococcus/drug effects
Pathogenicity5732506Osmotic fragility and viability of lysostaphin-induced staphylococcal spheroplasts.Schuhardt VT, Klesius PHJ Bacteriol10.1128/jb.96.3.734-737.19681968Anti-Bacterial Agents/*pharmacology, Hypertonic Solutions, Lysostaphin/pharmacology, Osmosis, *Protoplasts, Sodium Chloride/pharmacology, Staphylococcus/*drug effects/growth & development, Sucrose/pharmacology
Pathogenicity5764340Electron microscopy and viability of lysostaphin-induced staphylococcal spheroplasts, protoplast-like bodies, and protoplasts.Schuhardt VT, Huber TW, Pope LMJ Bacteriol10.1128/jb.97.1.396-401.19691969Anti-Bacterial Agents/*pharmacology, Cell Wall/*drug effects, DNA, Bacterial, Lysostaphin/pharmacology, Microscopy, Electron, Osmotic Fragility, Peptides, *Protoplasts, Spectrophotometry, Tritium
6077408Enhancement of antibiotic activity against Staphylococcus aureus by exposure to hyperbaric oxygen.Bornside GHAppl Microbiol10.1128/am.15.5.1020-1024.19671967Anti-Bacterial Agents/*pharmacology, Cephalothin/pharmacology, Kanamycin/pharmacology, Oxygen/*pharmacology, Oxytetracycline/pharmacology, Penicillins/pharmacology, Pressure, Staphylococcus/*growth & development, Streptomycin/pharmacology, Tetracycline/pharmacology
Enzymology6301566Synthesis of N-(2-hydroxypropyl)methacrylamide copolymers with antimicrobial activity.Solovskij MV, Ulbrich K, Kopecek JBiomaterials10.1016/0142-9612(83)90069-81983Acrylates/*chemical synthesis, Ampicillin, Anti-Bacterial Agents/*chemical synthesis/pharmacology, Bacteria/drug effects, Kinetics, Methacrylates/*chemical synthesis/pharmacology, Penicillanic AcidPathogenicity
Pathogenicity6353817[Model UF-2 mutant of Staphylococcus aureus 209 P for titrating Vibrio cholera enterotoxin].Pasternak NA, Ved'mina EA, Andrusenko IT, Shenderovich VA, Zhuravleva TPZh Mikrobiol Epidemiol Immunobiol1983Animals, Animals, Suckling, Bacteriological Techniques, Carcinoma, Ehrlich Tumor/microbiology, Enterotoxins/*analysis/pharmacology/toxicity, Guinea Pigs, In Vitro Techniques, Intestines/drug effects, *Mutation, Oxidoreductases/metabolism, Rabbits, Skin Absorption/drug effects, Staphylococcus aureus/*drug effects/enzymology, Vibrio cholerae/pathogenicityEnzymology
Pathogenicity6364128[Antifungal and antimicrobial activity of beta-ionone and vitamin A derivatives].Mikhlin ED, Radina VP, Dmitrovskii AA, Blinkova LP, Butova LGPrikl Biokhim Mikrobiol1983Anti-Bacterial Agents, Anti-Infective Agents/*pharmacology, Antifungal Agents/*pharmacology, Fusarium/drug effects, Microbial Sensitivity Tests, Micrococcus/drug effects, Mitosporic Fungi/drug effects, *Norisoprenoids, Retinoids/*pharmacology, Spores, Fungal/drug effects, Staphylococcus aureus/drug effects, Streptococcus pyogenes/drug effects, Structure-Activity Relationship, Terpenes/*pharmacology
Enzymology6647420[Action of dioxidine on the membrane apparatus of the bacterial cell].Rudzit EA, Ermachenko VA, Kutsemako RT, Dzhemukhadze GK, Kharat'ian EFPrikl Biokhim Mikrobiol1983Anti-Bacterial Agents/*pharmacology, Cell Membrane/drug effects/enzymology, Cytochromes/metabolism, Micrococcus/*drug effects/enzymology, Oxidoreductases/metabolism, Protoplasts/drug effects/enzymology, Quinoxalines/*pharmacology, Staphylococcus aureus/*drug effects/enzymologyPathogenicity
Pathogenicity6732206[Fatty acid composition of variant Staphylococcus aureus 209 P resistant to antibiotic AL-87].Smirnov VV, Churkina LN, Vasiurenko ZP, Kiprianova EA, Garagulia ADAntibiotiki1984Anti-Bacterial Agents/*antagonists & inhibitors, Chromatography, Gas, Drug Resistance, Microbial, Fatty Acids/*analysis, Genetic Variation/*drug effects, Pseudomonas, Staphylococcus aureus/analysis/cytology/*drug effects
Enzymology6832811Production, purification, and properties of a bacteriocin from Staphylococcus aureus isolated from saliva.Nakamura T, Yamazaki N, Taniguchi H, Fujimura SInfect Immun10.1128/iai.39.2.609-614.19831983Amino Acids/analysis, Bacteria/growth & development, Bacteriocins/analysis/*biosynthesis/isolation & purification/pharmacology, Humans, Isoelectric Point, Molecular Weight, Saliva/*microbiology, Staphylococcus aureus/isolation & purification/*metabolismPhylogeny
6967453Influence of carrier-specific, thymus-derived cells on the immunologlobulin M antibody response to staphylococcal lipoteichoic acid.Beining PR, Flannery GM, Prescott B, Baker PJInfect Immun10.1128/iai.29.1.132-139.19801980Animals, Antibodies, Bacterial/*biosynthesis, Antibody Specificity, Antibody-Producing Cells/immunology, Female, Immunization, Immunoglobulin M/*biosynthesis, *Lipopolysaccharides, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Phosphatidic Acids/*immunology, Staphylococcus aureus/*immunology, T-Lymphocytes/immunology, Teichoic Acids/*immunology
7447634Effect of immunization of guinea pigs on in vitro phagocytosis by polymorphonuclear leukocytes (PMNL).Tchorzewski H, Denys A, Grzybowski A, Malewska ZArch Immunol Ther Exp (Warsz)1980Animals, Antigens/*immunology, Antigens, Viral/immunology, Cattle, Guinea Pigs, In Vitro Techniques, Influenza A virus/immunology, Neutrophils/*immunology, Orthomyxoviridae/immunology, *Phagocytosis, Serum Albumin, Bovine/*immunology, Staphylococcus aureus/immunology
Enzymology7494504Alteration of bacteriolytic enzyme profile of Staphylococcus aureus during growth.Komatsuzawa H, Sugai M, Nakashima S, Suginaka HMicrobiol Immunol10.1111/j.1348-0421.1995.tb02253.x1995N-Acetylmuramoyl-L-alanine Amidase/*isolation & purification/metabolism, Staphylococcus aureus/*enzymology/growth & developmentPhylogeny
Metabolism7628982Binding affinities of beta-lactam antibodies for penicillin-binding protein 2' in methicillin-resistant staphylococcus aureus.Sumita Y, Fukasawa M, Mitsuhashi S, Inoue MJ Antimicrob Chemother10.1093/jac/35.4.4731995Anti-Bacterial Agents/*immunology, Antibodies, Bacterial/*metabolism, *Bacterial Proteins, Carrier Proteins/genetics/*metabolism, *Hexosyltransferases, Kinetics, Membranes/metabolism, *Methicillin Resistance/genetics, Microbial Sensitivity Tests, Muramoylpentapeptide Carboxypeptidase/genetics/*metabolism, Penicillin-Binding Proteins, *Peptidyl Transferases, Protein Binding, Staphylococcus aureus/drug effects/genetics/*metabolism, beta-LactamsEnzymology
Phylogeny7723694Isolation and characterization of Staphylococcus aureus mutants which form altered cell clusters.Sugai M, Komatsuzawa H, Ooku-Inomata K, Miyake Y, Ishida E, Suginaka HMicrobiol Immunol10.1111/j.1348-0421.1994.tb02158.x1994Acetylglucosaminidase/analysis, Muramidase/analysis, N-Acetylmuramoyl-L-alanine Amidase/*genetics, Staphylococcus aureus/*cytology/enzymology/*geneticsEnzymology
Enzymology7883705Identification of endo-beta-N-acetylglucosaminidase and N-acetylmuramyl-L-alanine amidase as cluster-dispersing enzymes in Staphylococcus aureus.Sugai M, Komatsuzawa H, Akiyama T, Hong YM, Oshida T, Miyake Y, Yamaguchi T, Suginaka HJ Bacteriol10.1128/jb.177.6.1491-1496.19951995Acetylglucosaminidase/isolation & purification/*metabolism/pharmacology, Bacterial Adhesion/*physiology, Bacterial Proteins/isolation & purification/*metabolism/pharmacology, Bacteriolysis, Blotting, Western, Mutagenesis, Insertional, Particle Size, Staphylococcus aureus/*enzymology/growth & developmentPhylogeny
Pathogenicity7898564Bacteriological evaluation of a new air turbine handpiece for preventing cross-contamination in dental procedures.Masuda K, Ohta M, Ohsuka S, Matsuyama M, Ashoori M, Usami T, Ito M, Ueda M, Kaneda TNagoya J Med Sci1994Bacteriological Techniques, Cross Infection/*prevention & control/transmission, Decontamination, *Dental Equipment, Evaluation Studies as Topic, Humans, *Infectious Disease Transmission, Patient-to-Professional
Metabolism8067117[The interaction of staphylococci with plasmin and its inhibitors].Zorin NA, Zhabin SG, Vorob'eva ONZh Mikrobiol Epidemiol Immunobiol1993Animals, Bacterial Proteins/metabolism, Cell Wall/metabolism, Drug Interactions, Fibrinolysin/*antagonists & inhibitors/*metabolism, Humans, Interferon-alpha/metabolism, Molecular Weight, Rabbits, Receptors, Cell Surface/metabolism, Receptors, Interferon/metabolism, Receptors, Peptide/metabolism, Receptors, Urokinase Plasminogen Activator, Staphylococcus aureus/*metabolismPathogenicity
Cultivation8319007[Modeling of the bactericidal effect of spiramycin. Choice of a pharmacodynamic model].Renard L, Sanders P, Laurentie MVet Res1993Culture Media, Dose-Response Relationship, Drug, Hydrogen-Ion Concentration, *Models, Biological, Spiramycin/*pharmacology, Staphylococcus aureus/*drug effects/growth & development, Time FactorsPathogenicity
Pathogenicity8572896Effect of hydrocortisone treatment on oxygen metabolism and phagocytosis of peripheral blood neutrophils in asthmatic patients, sensitive and resistant to glucocorticosteroid therapy.Jankowska R, Zak-Nejmark T, Malolepszy J, Nadobna G, Osos M, Medrala WArch Immunol Ther Exp (Warsz)1994Adult, Asthma/*blood/*drug therapy, Drug Resistance, Humans, Hydrocortisone/*therapeutic use, Luminescent Measurements, Middle Aged, Neutrophils/*drug effects/*metabolism, Oxygen/*blood, Phagocytosis/*drug effectsMetabolism
Pathogenicity8879559Synthesis and biological evaluation of an electronically activated isooxacephem.Hakimelahi GH, Tsay SC, Tso HH, Ramezani Z, Hwu JRBioorg Med Chem10.1016/0968-0896(96)00131-91996Anti-Bacterial Agents/*chemistry, Cephalosporins/*chemistry, Microbial Sensitivity Tests, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects
Pathogenicity9032632Prevention of infection in dental procedures.Matsuyama M, Usami T, Masuda K, Niimi N, Ohta M, Ueda MJ Hosp Infect10.1016/s0195-6701(97)90164-x1997Adult, Colony Count, Microbial, Cross Infection/*prevention & control, *Dental High-Speed Equipment, Disinfection/*methods, Equipment Contamination/*prevention & control, Equipment Design, Humans, Infection Control, Dental/*methods, Staphylococcus aureus, Streptococcus mutans, Suction
Phylogeny9142742Isolation and characterization of autolysin-defective mutants of Staphylococcus aureus that form cell packets.Kaneda SCurr Microbiol10.1007/s0028499001951997Methylnitronitrosoguanidine, Mutagenesis, Mutation, N-Acetylmuramoyl-L-alanine Amidase/*genetics, Staphylococcus aureus/*cytology/*genetics/growth & development
Enzymology9299402Identification of nitric oxide synthase in Staphylococcus aureus.Choi WS, Chang MS, Han JW, Hong SY, Lee HWBiochem Biophys Res Commun10.1006/bbrc.1997.71891997Blotting, Western, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Citrulline/metabolism, Electrophoresis, Polyacrylamide Gel, Kinetics, NADP/metabolism, Nitric Oxide/analysis, Nitric Oxide Synthase/isolation & purification/*metabolism, Staphylococcus aureus/*enzymology, ThermodynamicsMetabolism
Pathogenicity9341918Cephalosporin 3'-phloroglucide esters and 7-(phloroglucidamido) cephalosporins as novel antibacterial agents.Hwu JR, Moshfegh AA, Tsay SC, Lin CC, Tseng WN, Azaripour A, Mottaghian H, Hakimelahi GHJ Med Chem10.1021/jm960810e1997Anti-Bacterial Agents, Anti-Infective Agents/*chemical synthesis/chemistry/pharmacology, Benzhydryl Compounds/*chemical synthesis/pharmacology, Benzophenones/*chemical synthesis/pharmacology, Candida albicans/drug effects, Cephalosporins/*chemical synthesis/chemistry/pharmacology, Esters/chemical synthesis/pharmacology, Microbial Sensitivity Tests, Models, Molecular, Molecular Conformation, Molecular Structure, Pseudomonas aeruginosa/drug effects, Staphylococcus aureus/drug effects, beta-Lactamase Inhibitors
Pathogenicity9394239[Evaluation of reduced vancomycin susceptibility of MRSA strain Mu50 with various conditions of antibiotic susceptibility tests].Hanaki H, Hiramatsu KJpn J Antibiot1997Anti-Bacterial Agents/*pharmacology, Drug Resistance, Microbial, Humans, Methicillin Resistance, Microbial Sensitivity Tests/methods, Staphylococcal Infections/microbiology, Staphylococcus aureus/*drug effects/isolation & purification, Surgical Wound Infection/microbiology, Vancomycin/*pharmacologyEnzymology
Pathogenicity9400512Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin.Hiramatsu K, Aritaka N, Hanaki H, Kawasaki S, Hosoda Y, Hori S, Fukuchi Y, Kobayashi ILancet10.1016/S0140-6736(97)07324-81997Aged, Aged, 80 and over, Anti-Bacterial Agents/*pharmacology, Drug Resistance, Microbial, Electrophoresis, Gel, Pulsed-Field, Genotype, Hospitals, Humans, Japan, Male, *Methicillin Resistance, Microbial Sensitivity Tests, Prevalence, Sputum/microbiology, Staphylococcus aureus/*drug effects/genetics, Vancomycin/*pharmacologyEnzymology
Metabolism9597552[Mechanism of vancomycin resistance in MRSA strain Mu50].Hanaki H, Labischinski H, Sasaki K, Kuwahara-Arai K, Inaba Y, Hiramatsu KJpn J Antibiot1998Anti-Bacterial Agents/metabolism/*pharmacology, *Bacterial Proteins, Binding Sites, Carrier Proteins/metabolism, Cell Wall/metabolism/ultrastructure, Drug Resistance, Microbial, *Hexosyltransferases, Humans, Methicillin Resistance, Microscopy, Electron, Scanning Transmission, Muramoylpentapeptide Carboxypeptidase/metabolism, Penicillin-Binding Proteins, Peptidoglycan/metabolism, *Peptidyl Transferases, Pneumonia, Staphylococcal/microbiology, Staphylococcus aureus/cytology/*drug effects/metabolism, Surgical Wound Infection/microbiology, Vancomycin/metabolism/*pharmacologyPathogenicity
Metabolism9644600[Increase of non-amidated muropeptides in the cell wall of vancomycin-resistant Staphylococcus aureus (VRSA) strain Mu50].Hanaki H, Labischinski H, Inaba Y, Hiramatsu KJpn J Antibiot1998Acetylglucosamine/metabolism, Anti-Bacterial Agents/pharmacokinetics/*pharmacology, Cell Wall/*metabolism, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Humans, Peptidoglycan/*metabolism, Staphylococcus aureus/*drug effects/metabolism, Vancomycin/pharmacokinetics/*pharmacologyPathogenicity
Pathogenicity9796192[In vitro specific binding of Shiga toxin 1 and 2 by TAK-751S (Gb3 analog)].Takeda T, Yoshino K, Adachi E, Yamagata K, Uchida H, Okonogi K, Iizawa YKansenshogaku Zasshi10.11150/kansenshogakuzasshi1970.72.9241998Adsorption, *Bacterial Toxins, Diatomaceous Earth, *Enterotoxins, Escherichia coli O157, Humans, Shiga Toxins, *Trihexosylceramides, *Trisaccharides
10028666Identification and semiquantitative estimation of antibiotics added to complete feeds, premixes, and concentrates.Gafner JLJ AOAC Int1999*Animal Feed, Anti-Bacterial Agents/*analysis, Chromatography, Thin Layer, Glycopeptides, Microbial Sensitivity Tests, *Quality Control, Software Design
Pathogenicity10349564Feasibility of an in vitro microbiological model as an alternative to the rabbit eye model.Devarajan PV, Bhogte CP, Majali AB, Sabharwal SDrug Dev Ind Pharm10.1081/ddc-1001022381999Administration, Topical, Animal Testing Alternatives/*methods, Animals, Evaluation Studies as Topic, Eye/*microbiology, Gentamicins/*administration & dosage, In Vitro Techniques, Male, Models, Biological, Polyvinyl Alcohol/chemistry, Pseudomonas aeruginosa/*drug effects, Rabbits, Staphylococcus aureus/*drug effects, Time Factors
Cultivation10419208Modeling the aerobic growth and decline of Staphylococcus aureus as affected by pH and potassium sorbate concentration.Giannuzzi L, Contreras E, Zaritzky NJ Food Prot10.4315/0362-028x-62.4.3561999Aerobiosis, Colony Count, Microbial, Culture Media, Hydrogen-Ion Concentration, *Models, Biological, Sorbic Acid/*pharmacology, Staphylococcus aureus/drug effects/*growth & developmentPathogenicity
Pathogenicity10991847In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum.Zhang H, Yoshida S, Aizawa T, Murakami R, Suzuki M, Koganezawa N, Matsuura A, Miyazawa M, Kawano K, Nitta K, Kato YAntimicrob Agents Chemother10.1128/AAC.44.10.2701-2705.20002000Amino Acid Sequence, Animals, Anti-Bacterial Agents/antagonists & inhibitors/biosynthesis/*pharmacology, Ascaris suum/chemistry/*metabolism, Bacteria/*drug effects, Chromatography, High Pressure Liquid, Chromatography, Ion Exchange, Genetic Vectors, Helminth Proteins/antagonists & inhibitors/biosynthesis/*pharmacology, Hemolysis/drug effects, Humans, In Vitro Techniques, Microbial Sensitivity Tests, Molecular Sequence Data, Recombinant Proteins/pharmacology, Yeasts/drug effectsGenetics
Pathogenicity11020277Design, synthesis, and SAR of novel carbapenem antibiotics with high stability to Xanthomonas maltophilia oxyiminocephalosporinase type II.Hakimelahi GH, Moosavi-Movahedi AA, Tsay SC, Tsai FY, Wright JD, Dudev T, Hakimelahi S, Lim CJ Med Chem10.1021/jm000213z2000Carbapenems/*chemical synthesis/chemistry/pharmacology, Colony Count, Microbial, Drug Resistance, Microbial, Enzyme Inhibitors/*chemical synthesis/chemistry/pharmacology, Microbial Sensitivity Tests, Models, Molecular, Stenotrophomonas maltophilia/*chemistry/drug effects, Stereoisomerism, Structure-Activity Relationship, beta-Lactamases/*chemistry
Pathogenicity11293238Antimicrobial activity of selected non-antibiotics--activity of methotrexate against Staphylococcus aureus strains.Kruszewska H, Zareba T, Tyski SActa Pol Pharm2000Anti-Bacterial Agents/*pharmacology, Humans, Methicillin Resistance, Methotrexate/*pharmacology, Staphylococcus aureus/*drug effects
Enzymology11397624Effects of Helichrysum italicum extract on growth and enzymatic activity of Staphylococcus aureus.Nostro A, Bisignano G, Angela Cannatelli M, Crisafi G, Paola Germano M, Alonzo VInt J Antimicrob Agents10.1016/s0924-8579(01)00336-32001Anti-Bacterial Agents/isolation & purification/pharmacology, *Asteraceae, Coagulase/antagonists & inhibitors, Deoxyribonucleases/antagonists & inhibitors, Enzyme Inhibitors/isolation & purification/pharmacology, Humans, In Vitro Techniques, Lipase/antagonists & inhibitors, Micrococcal Nuclease/antagonists & inhibitors, Plant Extracts/pharmacology, *Plants, Medicinal, Staphylococcus aureus/*drug effects/enzymology/growth & development/isolation & purificationPhylogeny
Phylogeny11509983Antibacterial activity of Hydrastis canadensis extract and its major isolated alkaloids.Scazzocchio F, Cometa MF, Tomassini L, Palmery MPlanta Med10.1055/s-2001-164932001Alkaloids/chemistry/isolation & purification/*pharmacology, Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology, Bacteria/*drug effects, Magnoliopsida/*chemistry, Microbial Sensitivity Tests, Plant Extracts/pharmacology, Time FactorsEnzymology
Pathogenicity11548201Comparison of the effects in vitro of tea tree oil and plaunotol on methicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus.Hada T, Furuse S, Matsumoto Y, Hamashima H, Masuda K, Shiojima K, Arai T, Sasatsu MMicrobios2001Anti-Bacterial Agents/*pharmacology, Diterpenes, Fatty Alcohols/*pharmacology, Humans, Methicillin/pharmacology, *Methicillin Resistance, Microbial Sensitivity Tests/methods, Oils, Volatile/pharmacology, Penicillins/pharmacology, Staphylococcus aureus/*drug effects/growth & development, Tea Tree Oil/*pharmacology
Pathogenicity12024816[The effect of the intra- and extracellular metabolites of microorganisms isolated from various ecotopes on the catalase activity of Staphylococcus aureus 6538P].Bukharin OV, Sgibnev AV, Cherkasov SV, Ivanov IuBMikrobiologiia2002Biological Factors/*pharmacology, Catalase/*antagonists & inhibitors, Culture Media, Enzyme Inhibitors/pharmacology, Humans, Hydrogen Peroxide/pharmacology, Staphylococcus aureus/drug effects/*enzymology/growth & developmentCultivation
Pathogenicity12475283Green-leaf-derived C6-aroma compounds with potent antibacterial action that act on both Gram-negative and Gram-positive bacteria.Nakamura S, Hatanaka AJ Agric Food Chem10.1021/jf025808c2002Alcohols/*pharmacology, Aldehydes/*pharmacology, Anti-Bacterial Agents/*pharmacology, Cyclodextrins/chemistry/pharmacology, Escherichia coli/drug effects, Gases, Gram-Negative Bacteria/*drug effects, Gram-Positive Bacteria/*drug effects, Kinetics, Methicillin Resistance, Odorants/analysis, Plant Leaves/*chemistry, Salmonella enteritidis/drug effects, Solutions, Staphylococcus aureus/drug effects, *alpha-CyclodextrinsEnzymology
12476876Interaction of iodine with 2-hydroxypropyl-alpha-cyclodextrin and its bactericidal activity.Tomono K, Goto H, Suzuki T, Ueda H, Nagai T, Watanabe JDrug Dev Ind Pharm10.1081/ddc-12001535920022-Hydroxypropyl-beta-cyclodextrin, Cyclodextrins/*chemistry, Drug Stability, Iodine/*chemistry, Microbial Sensitivity Tests, Solubility, *alpha-Cyclodextrins, *beta-Cyclodextrins
Enzymology12770704Purification and characterization of nitric oxide synthase from Staphylococcus aureus.Hong IS, Kim YK, Choi WS, Seo DW, Yoon JW, Han JW, Lee HY, Lee HWFEMS Microbiol Lett10.1016/S0378-1097(03)00254-42003Enzyme Inhibitors/pharmacology, Molecular Weight, NG-Nitroarginine Methyl Ester/pharmacology, Nitric Oxide Synthase/chemistry/*isolation & purification/*metabolism, Staphylococcus aureus/*enzymologyPhylogeny
Pathogenicity12956062Application of the Barton photochemical reaction in the synthesis of 1-dethia-3-aza-1-carba-2-oxacephem: a novel agent against resistant pathogenic microorganisms.Hakimelahi GH, Li PC, Moosavi-Movahedi AA, Chamani J, Khodarahmi GA, Ly TW, Valiyev F, Leong MK, Hakimelahi S, Shia KS, Chao IOrg Biomol Chem10.1039/b304167k2003Anti-Infective Agents/*chemical synthesis/chemistry/*pharmacology, Cell Division/drug effects, Cells, Cultured, Cephalosporins/*chemical synthesis/chemistry/*pharmacology, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/chemistry, Drug Resistance, Bacterial, Enzyme Inhibitors/chemistry/pharmacology, Escherichia coli/*drug effects/enzymology/genetics, Humans, Isomerism, Klebsiella pneumoniae/drug effects/genetics, Methicillin/pharmacology, Microbial Sensitivity Tests, Models, Molecular, Pseudomonas aeruginosa/*drug effects/enzymology/genetics, Staphylococcus aureus/*drug effects/enzymology/genetics, beta-Lactamase Inhibitors, beta-Lactams/chemistry/pharmacologyEnzymology
Pathogenicity14529966A kinetic microplate method for quantifying the antibacterial properties of biological fluids.Holowachuk SA, Bal'a MF, Buddington RKJ Microbiol Methods10.1016/s0167-7012(03)00190-82003Animals, Anti-Bacterial Agents/*pharmacology, Area Under Curve, Escherichia coli/drug effects/growth & development, Extracellular Fluid/chemistry/*metabolism, Gentamicins/*pharmacology, Lactobacillus/drug effects/growth & development, Microbial Sensitivity Tests, Pancreas/metabolism, Staphylococcus aureus/drug effects/growth & development, SwineMetabolism
Pathogenicity14758005Diastereomeric selective effects for growth inhibition of synthesized mini parallel double-stranded peptides on Escherichia coli and Staphylococcus aureus.Kobayashi S, Atuchi N, Kobayashi H, Shiraishi A, Hamashima H, Tanaka AChem Pharm Bull (Tokyo)10.1248/cpb.52.2042004Anti-Bacterial Agents/*chemical synthesis/chemistry/pharmacokinetics/pharmacology, Cell Line, Tumor, Cell Membrane Permeability/drug effects, Circular Dichroism, Escherichia coli/*drug effects/growth & development, Humans, Microbial Sensitivity Tests, Models, Molecular, Molecular Structure, Peptides/*chemical synthesis/chemistry/pharmacokinetics/pharmacology, Staphylococcus aureus/*drug effects/growth & development, Stereoisomerism, Structure-Activity RelationshipEnzymology
Metabolism15028958Nonparallel secretion of antibacterial activity and protein in porcine pancreatic juice.Holowachuk SA, Bal'a MF, Gerard PD, Buddington RKPancreas10.1097/00006676-200403000-000172004Animals, Anti-Bacterial Agents/*pharmacology, Eating, Enzymes/*metabolism, Pancreatic Juice/*metabolism, Staphylococcus aureus/drug effects, SwineEnzymology
Pathogenicity15129996Microbiological assay for enrofloxacin injection.e Souza MJ, Bittencourt CF, e Souza Filho Pda SInt J Pharm10.1016/j.ijpharm.2003.11.0122004Anti-Bacterial Agents/*pharmacology/standards, Colony Count, Microbial/*methods, Enrofloxacin, Fluoroquinolones/*pharmacology/standards, Injections, Quinolones/*pharmacology/standards, Reference Standards, Reproducibility of Results, Sensitivity and Specificity, Staphylococcus aureus/*drug effects/growth & development
Pathogenicity15804533Carbapenem-based prodrugs. Design, synthesis, and biological evaluation of carbapenems.Hakimelahi GH, Moosavi-Movahedi AA, Saboury AA, Osetrov V, Khodarahmi GA, Shia KSEur J Med Chem10.1016/j.ejmech.2004.11.0022005Anti-Bacterial Agents/chemical synthesis/chemistry/pharmacology, Carbapenems/*chemical synthesis/chemistry/*pharmacology, *Drug Design, Enzyme Inhibitors/chemical synthesis/chemistry/pharmacology, Molecular Structure, Prodrugs/*chemical synthesis/chemistry/*pharmacology, beta-Lactamase Inhibitors, beta-Lactamases/metabolismMetabolism
Pathogenicity16358986Phagocytic and bactericidal activity and morphological parameters of blood platelets in patients with Trichinella spiralis infection.Matowicka-Karna J, Kemona H, Dymicka-Piekarska V, Butkiewicz ARocz Akad Med Bialymst2005Adult, Aged, Animals, Antiparasitic Agents/therapeutic use, Blood Bactericidal Activity/*physiology, Blood Platelets/*immunology, Case-Control Studies, Female, Humans, Male, Middle Aged, Phagocytosis/*physiology, Platelet Activation, Trichinella spiralis/*pathogenicity, Trichinellosis/drug therapy/*immunology
Pathogenicity16410969Studies on antimicrobial activity, in vitro, of Physalis angulata L. (Solanaceae) fraction and physalin B bringing out the importance of assay determination.Silva MT, Simas SM, Batista TG, Cardarelli P, Tomassini TCMem Inst Oswaldo Cruz10.1590/s0074-027620050007000182006Agar, Anti-Bacterial Agents/*therapeutic use, Candida albicans/*drug effects, Culture Media, Drug Evaluation, Preclinical, Gram-Negative Bacteria/*drug effects, Gram-Positive Bacteria/*drug effects, Lactones/*therapeutic use, Microbial Sensitivity Tests/methods, *Physalis, Plant Extracts/pharmacology, Secosteroids, Steroids/*therapeutic useCultivation
Pathogenicity16427259Multifactorial aspects of antimicrobial activity of propolis.Scazzocchio F, D'Auria FD, Alessandrini D, Pantanella FMicrobiol Res10.1016/j.micres.2005.12.0032006Anti-Bacterial Agents/*pharmacology, Ethanol/pharmacology, Microbial Sensitivity Tests, Propolis/*pharmacology, Staphylococcus aureus/*drug effects/growth & development
Pathogenicity16651758Synthesis and biological properties of gemini quaternary ammonium compounds, 5,5'-[2,2'-(alpha,omega-polymethylnedicarbonyldioxy)diethyl]bis-(3-alkyl-4-methyl thiazolium iodide) and 5,5'-[2,2'-(p-phenylenedicarbonyldioxy)diethyl]bis(3-alkyl-4-methylthiazolium bromide).Shirai A, Sumitomo T, Yoshida M, Kaimura T, Nagamune H, Maeda T, Kourai HChem Pharm Bull (Tokyo)10.1248/cpb.54.6392006Alkylation, Anti-Bacterial Agents/chemical synthesis/pharmacology, Anti-Infective Agents/*chemical synthesis/pharmacology, Antifungal Agents/chemical synthesis/pharmacology, Chemical Phenomena, Chemistry, Physical, Chromatography, Thin Layer, Escherichia coli/drug effects, Fungi/drug effects, Magnetic Resonance Spectroscopy, Microbial Sensitivity Tests, Quaternary Ammonium Compounds/*chemical synthesis/*pharmacology, Staphylococcus aureus, Structure-Activity Relationship, Thiazoles/*chemical synthesis/*pharmacology, Yeasts/drug effects
Pathogenicity17927050The mechanism of the bactericidal activity of hinokitiol.Morita Y, Sakagami Y, Okabe T, Ohe T, Inamori Y, Ishida NBiocontrol Sci10.4265/bio.12.1012007Adenine/metabolism, Anti-Infective Agents/*pharmacology, Cell Membrane Permeability/drug effects, Escherichia coli/*drug effects/growth & development/metabolism, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, Monoterpenes/*pharmacology, Oxygen Consumption/drug effects, Staphylococcus aureus/*drug effects/growth & development/metabolism, Tropolone/*analogs & derivatives/pharmacologyMetabolism
Pathogenicity18041957Antibacterial activity of guava (Psidium guajava L.) and Neem (Azadirachta indica A. Juss.) extracts against foodborne pathogens and spoilage bacteria.Mahfuzul Hoque MD, Bari ML, Inatsu Y, Juneja VK, Kawamoto SFoodborne Pathog Dis10.1089/fpd.2007.00402007Anti-Bacterial Agents/*pharmacology, Azadirachta/*chemistry, Colony Count, Microbial, Dose-Response Relationship, Drug, Ethanol, Food Microbiology, Food Preservation/*methods, Gram-Negative Bacteria/*drug effects/growth & development, Gram-Positive Bacteria/*drug effects/growth & development, Humans, Hydrogen-Ion Concentration, Microbial Sensitivity Tests, Plant Extracts/*pharmacology, Psidium/*chemistry, Species Specificity, TemperatureBiotechnology
Biotechnology18554739Interactions in dual species biofilms between Listeria monocytogenes EGD-e and several strains of Staphylococcus aureus.Rieu A, Lemaitre JP, Guzzo J, Piveteau PInt J Food Microbiol10.1016/j.ijfoodmicro.2008.05.0062008Bacterial Adhesion/physiology, Biofilms/*growth & development, Colony Count, Microbial, Equipment Contamination/*prevention & control, Food Contamination/*prevention & control, Food Microbiology, Food-Processing Industry, Listeria monocytogenes/*physiology, Microscopy, Electron, Scanning, Species Specificity, Stainless Steel, Staphylococcus aureus/*physiologyPhylogeny
Metabolism18797139No relationship exists between PBP 2a amounts expressed in different MRSA strains obtained clinically and their beta-lactam MIC values.Parvez MA, Shibata H, Nakano T, Niimi S, Fujii N, Arakaki N, Higuti TJ Med Invest10.2152/jmi.55.2462008Bacterial Proteins/analysis/genetics/*metabolism, Humans, Immunoblotting, In Vitro Techniques, Methicillin Resistance, Methicillin-Resistant Staphylococcus aureus/*drug effects/genetics/isolation & purification/*metabolism, Microbial Sensitivity Tests, Penicillin-Binding Proteins/analysis/genetics/*metabolism, Species Specificity, Staphylococcal Infections/drug therapy/microbiology, beta-Lactams/administration & dosage/*pharmacologyPathogenicity
Pathogenicity19344741Development and validation of a microbiological agar assay for determination of cefuroxime sodium in pharmaceutical preparations.Schmidt CA, Agarrayua DA, Laporta LV, Machado JC, Manfio ML, Bittencourt CFJ Microbiol Methods10.1016/j.mimet.2009.03.0122009Agar/analysis, Anti-Bacterial Agents/*pharmacology, Cefuroxime/*pharmacology, Microbial Sensitivity Tests, *Microbiological Techniques, Pharmaceutical Preparations/*analysis, Staphylococcus aureus/drug effects
Pathogenicity19664066Lethal effect of chitosan-Ag (I) films on Staphylococcus aureus as evaluated by electron microscopy.Diaz-Visurraga J, Garcia A, Cardenas GJ Appl Microbiol10.1111/j.1365-2672.2009.04447.x2009Anti-Infective Agents/chemistry/*pharmacology, Bacteriolysis, Cell Wall/ultrastructure, Chitosan/chemistry/*pharmacology, Microbial Sensitivity Tests, Microscopy, Electron, Silver/chemistry/*pharmacology, Staphylococcus aureus/*drug effects/ultrastructure
Pathogenicity20490884Cellular effects induced by Inula graveolens and Santolina corsica essential oils on Staphylococcus aureus.Guinoiseau E, Luciani A, Rossi PG, Quilichini Y, Ternengo S, Bradesi P, Berti LEur J Clin Microbiol Infect Dis10.1007/s10096-010-0943-x2010Anti-Bacterial Agents/isolation & purification/*pharmacology, Asteraceae/*chemistry, Cell Membrane/drug effects/ultrastructure, Cell Wall/drug effects/ultrastructure, Humans, Inula/*chemistry, Microbial Sensitivity Tests, Microbial Viability/drug effects, Microscopy, Electron, Transmission, Oils, Volatile/isolation & purification/*pharmacology, Staphylococcus aureus/*drug effects/ultrastructure, Time FactorsEnzymology
Phylogeny20513963Isolation of bacteriocin-like substances producing bacteria from finished cattle-manure compost and activity evaluation against some food-borne pathogenic and spoilage bacteria.Abdel-Mohsein H, Yamamoto N, Otawa K, Tada C, Nakai YJ Gen Appl Microbiol10.2323/jgam.56.1512010Animals, Anti-Bacterial Agents/pharmacology, Bacteriocins/*biosynthesis/pharmacology, Cattle, Enterobacteriaceae/classification/*drug effects/pathogenicity, Food Contamination, *Food Microbiology, Gram-Positive Cocci/classification/*drug effects/pathogenicity, Manure, Microbial Sensitivity Tests, Salmonella/classification/drug effects/*isolation & purification/metabolism, Shigella/classification/drug effects/*isolation & purification/metabolism, SoilPathogenicity
Pathogenicity20562272Direct observation and analysis of bacterial growth on an antimicrobial surface.Yamada H, Takahashi N, Okuda S, Tsuchiya Y, Morisaki HAppl Environ Microbiol10.1128/AEM.00576-102010Cell Cycle/*drug effects, Culture Media/chemistry, Disinfectants/*pharmacology, Escherichia coli/*drug effects/*growth & development/metabolism, Microbial Sensitivity Tests/methods, Staphylococcus aureus/*drug effects/*growth & development/metabolismMetabolism
Pathogenicity20584079In vitro effect of branch extracts of Juniperus species from Turkey on Staphylococcus aureus biofilm.Marino A, Bellinghieri V, Nostro A, Miceli N, Taviano MF, Guvenc A, Bisignano GFEMS Immunol Med Microbiol10.1111/j.1574-695X.2010.00705.x2010Anti-Bacterial Agents/chemistry/isolation & purification/*pharmacology, Biofilms/*drug effects, Biomass, Chromatography, Thin Layer, Colony Count, Microbial, Juniperus/*chemistry, Microbial Sensitivity Tests, Microbial Viability/drug effects, Plant Extracts/chemistry/isolation & purification/*pharmacology, Spectrophotometry, Staphylococcus aureus/*drug effects/physiology, TurkeyEnzymology
Pathogenicity20686274Antibacterial activity of 5-dialkylaminomethylhydantoins and related compounds.Fujisaki F, Shoji K, Shimodouzono M, Kashige N, Miake F, Sumoto KChem Pharm Bull (Tokyo)10.1248/cpb.58.11232010Anti-Bacterial Agents/chemical synthesis/chemistry/*pharmacology, Escherichia coli/*drug effects, Hydantoins/chemical synthesis/chemistry/*pharmacology, Microbial Sensitivity Tests, Molecular Structure, Staphylococcus aureus/*drug effects, Stereoisomerism
Pathogenicity20798583Antimicrobial activities of 1,4-benzoquinones and wheat germ extract.Kim MH, Jo SH, Ha KS, Song JH, Jang HD, Kwon YIJ Microbiol Biotechnol10.4014/jmb.1004.040372010Anti-Bacterial Agents/chemistry/*pharmacology, Bacteria/drug effects, Benzoquinones/chemistry/*pharmacology, Microbial Sensitivity Tests, Molecular Structure, Plant Extracts/chemistry/*pharmacology, Triticum/*chemistry
Metabolism20938718Antibacterial effect of silver nanoparticles on Staphylococcus aureus.Li WR, Xie XB, Shi QS, Duan SS, Ouyang YS, Chen YBBiometals10.1007/s10534-010-9381-62010Acetyltransferases/metabolism, Anti-Bacterial Agents/chemistry/*pharmacology, Cell Wall/drug effects, Dose-Response Relationship, Drug, Glycerolphosphate Dehydrogenase/antagonists & inhibitors/metabolism, Metal Nanoparticles/*chemistry, Microbial Sensitivity Tests, Oxidoreductases/antagonists & inhibitors/metabolism, Proteomics, Recombinases/antagonists & inhibitors/metabolism, Silver/chemistry/*pharmacology, Staphylococcus aureus/cytology/*drug effects/enzymologyEnzymology
Pathogenicity21652210A concise synthesis and antimicrobial activities of 3-polyamino-23,24-bisnorcholanes as steroid-polyamine conjugates.Kim HS, Khan SN, Jadhav JR, Jeong JW, Jung K, Kwak JHBioorg Med Chem Lett10.1016/j.bmcl.2011.05.0482011Anti-Infective Agents/*chemical synthesis/chemistry/*pharmacology, Cholanes/*chemical synthesis/chemistry/*pharmacology, Gram-Positive Bacteria/*drug effects, Humans, Microbial Sensitivity Tests, Polyamines/chemical synthesis/chemistry/pharmacology, Structure-Activity Relationship
22059662Effect of chitosan in meat preservation.Darmadji P, Izumimoto MMeat Sci10.1016/0309-1740(94)90114-71994
Pathogenicity22736550Enhanced photoinactivation of Staphylococcus aureus with nanocomposites containing plasmonic particles and hematoporphyrin.Khlebtsov BN, Tuchina ES, Khanadeev VA, Panfilova EV, Petrov PO, Tuchin VV, Khlebtsov NGJ Biophotonics10.1002/jbio.2012000792012Gold/chemistry, Hematoporphyrins/*chemistry, *Light, Metal Nanoparticles/chemistry, Microbial Viability/*radiation effects, Nanocomposites/*chemistry, Optical Phenomena, Photosensitizing Agents/chemistry/*pharmacology, Porosity, Silicon Dioxide/chemistry, Silver/chemistry, Staphylococcus aureus/*drug effects/physiology/*radiation effects, Temperature
Pathogenicity23928379Antimicrobial activity of quinoxaline 1,4-dioxide with 2- and 3-substituted derivatives.Vieira M, Pinheiro C, Fernandes R, Noronha JP, Prudencio CMicrobiol Res10.1016/j.micres.2013.06.0152013Anti-Infective Agents/chemistry/*pharmacology, Candida albicans/*drug effects, Escherichia coli/*drug effects, Microbial Sensitivity Tests, Microbial Viability/drug effects, Quinoxalines/chemistry/*pharmacology, Saccharomyces cerevisiae/*drug effects, Staphylococcus aureus/*drug effects
Pathogenicity24053648Developing a microbiological growth inhibition screening assay for the detection of 27 veterinary drugs from 13 different classes in animal feedingstuffs.Bohn T, Pellet T, Boscher A, Hoffmann LFood Addit Contam Part A Chem Anal Control Expo Risk Assess10.1080/19440049.2013.8324002013Animal Feed/*analysis, Animals, Anti-Bacterial Agents/*analysis, Cattle, Coccidiostats/*analysis, Disk Diffusion Antimicrobial Tests/*methods, Drug Residues, European Union, Reproducibility of Results, Sheep, Swine, Veterinary Drugs/*analysis
Pathogenicity24528382Evaluation of antibacterial and cytotoxic effects of nano-sized bioactive glass/collagen composites releasing tetracycline hydrochloride.Rivadeneira J, Di Virgilio AL, Audisio MC, Boccaccini AR, Gorustovich AAJ Appl Microbiol10.1111/jam.124762014Anti-Bacterial Agents/chemistry/*pharmacology, Biocompatible Materials/chemistry/*pharmacology, Body Fluids, Cell Line, Tumor, Collagen/chemistry, Glass/chemistry, Humans, Nanocomposites/*chemistry, Osteoblasts/drug effects, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Tetracycline/*pharmacology
Pathogenicity24848589Antimicrobial effect of Dinoponera quadriceps (Hymenoptera: Formicidae) venom against Staphylococcus aureus strains.Lima DB, Torres AF, Mello CP, de Menezes RR, Sampaio TL, Canuto JA, da Silva JJ, Freire VN, Quinet YP, Havt A, Monteiro HS, Nogueira NA, Martins AMJ Appl Microbiol10.1111/jam.125482014Animals, Ant Venoms/*pharmacology, Anti-Bacterial Agents/*pharmacology, Ants, Staphylococcus aureus/*drug effects
Pathogenicity24881665Salusin-beta, an antimicrobially active peptide against Gram-positive bacteria.Kimura M, Shindo M, Moriizumi T, Tagawa N, Fujinami A, Kato I, Uchida YChem Pharm Bull (Tokyo)10.1248/cpb.c14-001032014Dose-Response Relationship, Drug, Gram-Positive Bacteria/*drug effects, Humans, Intercellular Signaling Peptides and Proteins/chemistry/*pharmacology, Microbial Sensitivity Tests, Protein Conformation, Structure-Activity Relationship
Pathogenicity24907739Antibacterial performance of ZnO-based fillers with mesoscale structured morphology in model medical PVC composites.Machovsky M, Kuritka I, Bazant P, Vesela D, Saha PMater Sci Eng C Mater Biol Appl10.1016/j.msec.2014.04.0342014Anti-Bacterial Agents/*chemistry/pharmacology, Composite Resins/chemistry, Escherichia coli/drug effects, Polyvinyl Chloride/*chemistry, Staphylococcus aureus/drug effects, Zinc Oxide/*chemistry
Pathogenicity25353630TLR2 activation in corneal stromal cells by Staphylococcus aureus-induced keratitis.Marino A, Pergolizzi S, Lauriano ER, Santoro G, Spataro F, Cimino F, Speciale A, Nostro A, Bisignano GAPMIS10.1111/apm.123332014Animals, Cell Differentiation, Corneal Keratocytes/cytology, Corneal Stroma/cytology/microbiology/pathology, Enzyme Activation, Inflammation/immunology/microbiology, Interleukin-8/biosynthesis/genetics/metabolism, Keratitis/*immunology/microbiology, Myofibroblasts/cytology, Organ Culture Techniques, RNA, Messenger/biosynthesis, Rabbits, Staphylococcal Infections/*immunology/microbiology, Staphylococcus aureus/*immunology, Stromal Cells/*immunology, Toll-Like Receptor 2/biosynthesis/genetics/*immunologyMetabolism
25523046Synthesis, characterization, optical and antimicrobial studies of polyvinyl alcohol-silver nanocomposites.Mahmoud KHSpectrochim Acta A Mol Biomol Spectrosc10.1016/j.saa.2014.11.0742014Anti-Infective Agents/chemical synthesis/*chemistry, Aspergillus niger, Bacillus subtilis, Carbon/chemistry, Escherichia coli, Metal Nanoparticles/*chemistry, Microbial Sensitivity Tests, Microscopy, Electron, Transmission, Nanocomposites/*chemistry, Nanotechnology, Optics and Photonics, Particle Size, Polyvinyl Alcohol/*chemistry, Pseudomonas aeruginosa, Refractometry, Silver/*chemistry, Spectrophotometry, Infrared, Staphylococcus aureus
Pathogenicity26414807Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine.Pathan NB, Parvez A, Bader A, Shaheen U, Hadda TBEur J Med Chem10.1016/j.ejmech.2013.12.0362014Anti-Bacterial Agents/*chemical synthesis/chemistry/*pharmacology, Crystallography, X-Ray, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Escherichia coli/drug effects, Microbial Sensitivity Tests, Molecular Structure, Pyrimidines/*chemistry/*pharmacology, Salmonella/drug effects, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects, Structure-Activity Relationship
Genetics26564052Complete Genome Sequence of the Drug-Naive Classical Staphylococcus aureus Strain FDA209P.Singh M, Sasaki T, Matsuo M, Morimoto Y, Aiba Y, Hiramatsu KGenome Announc10.1128/genomeA.01343-152015Pathogenicity
Pathogenicity26664112Green synthesis of silver nanoparticles using cranberry powder aqueous extract: characterization and antimicrobial properties.Ashour AA, Raafat D, El-Gowelli HM, El-Kamel AHInt J Nanomedicine10.2147/IJN.S872682015Animals, Anti-Infective Agents/*pharmacology, Bacteria/drug effects/ultrastructure, Gels/pharmacology, Green Chemistry Technology/*methods, Male, Metal Nanoparticles/*chemistry/ultrastructure, Microbial Sensitivity Tests, Particle Size, Plant Extracts/chemistry/*pharmacology, Poloxamer/pharmacology, Powders, Rats, Silver/*chemistry, Spectrophotometry, Ultraviolet, Spectroscopy, Fourier Transform Infrared, Static Electricity, Vaccinium macrocarpon/*chemistry, Wound Healing/drug effects
Biotechnology26770255In Vitro Antimicrobial Activity and Effect on Biofilm Production of a White Grape Juice (Vitis vinifera) Extract.Filocamo A, Bisignano C, Mandalari G, Navarra MEvid Based Complement Alternat Med10.1155/2015/8562432015
Pathogenicity27043217Laxitextines A and B, Cyathane Xylosides from the Tropical Fungus Laxitextum incrustatum.Mudalungu CM, Richter C, Wittstein K, Abdalla MA, Matasyoh JC, Stadler M, Sussmuth RDJ Nat Prod10.1021/acs.jnatprod.5b009502016Animals, Anti-Bacterial Agents/chemistry/*isolation & purification/pharmacology, Antineoplastic Agents/chemistry/*isolation & purification/pharmacology, Bacillus subtilis/drug effects, Diterpenes/chemistry/*isolation & purification/pharmacology, Drug Screening Assays, Antitumor, Female, Glycosides/chemistry/*isolation & purification/pharmacology, Humans, MCF-7 Cells, Methicillin Resistance/drug effects, Mice, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Staphylococcus aureus/drug effectsEnzymology
27247773The application of alkaline and acidic electrolyzed water in the sterilization of chicken breasts and beef liver.Shimamura Y, Shinke M, Hiraishi M, Tsuchiya Y, Masuda SFood Sci Nutr10.1002/fsn3.3052015
Pathogenicity27400878Antimicrobial and anti-Quorum Sensing activities of selected medicinal plants of Ethiopia: Implication for development of potent antimicrobial agents.Bacha K, Tariku Y, Gebreyesus F, Zerihun S, Mohammed A, Weiland-Brauer N, Schmitz RA, Mulat MBMC Microbiol10.1186/s12866-016-0765-92016Anti-Infective Agents/isolation & purification/*pharmacology, Bacillus cereus/drug effects, Bacteria/drug effects, Biofilms/drug effects, Candida albicans/drug effects, Drug Resistance, Microbial, Escherichia coli/drug effects, Ethiopia, Fruit/chemistry, Fungi/drug effects, Microbial Sensitivity Tests, Plant Extracts/*pharmacology, Plants, Medicinal/*chemistry, Pseudomonas aeruginosa/drug effects, Quorum Sensing/*drug effects, Seeds/chemistry, Staphylococcus aureus/drug effects, Tracheophyta/chemistryEnzymology
Pathogenicity27855063In Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin.Singh M, Matsuo M, Sasaki T, Morimoto Y, Hishinuma T, Hiramatsu KAntimicrob Agents Chemother10.1128/AAC.01154-162017Anti-Bacterial Agents/pharmacology, Isoleucine-tRNA Ligase/antagonists & inhibitors/genetics, Microbial Sensitivity Tests, Mupirocin/pharmacology, Mutation, Polymorphism, Single Nucleotide, Staphylococcus aureus/*drug effects/*genetics, Vancomycin/*pharmacology, Vancomycin Resistance/genetics
29494511Synthesis and Effect of Hierarchically Structured Ag-ZnO Hybrid on the Surface Antibacterial Activity of a Propylene-Based Elastomer Blends.Bazant P, Sedlacek T, Kuritka I, Podlipny D, Holcapkova PMaterials (Basel)10.3390/ma110303632018
Pathogenicity29577952Lipid transfer protein isolated from noni seeds displays antibacterial activity in vitro and improves survival in lethal sepsis induced by CLP in mice.Souza AA, Costa AS, Campos DCO, Batista AHM, Sales GWP, Nogueira NAP, Alves KMM, Coelho-de-Souza AN, Oliveira HDBiochimie10.1016/j.biochi.2018.03.0112018Animals, Anti-Bacterial Agents/*administration & dosage/chemistry, Carrier Proteins/*administration & dosage/genetics/isolation & purification, Cecum/pathology/surgery, Disease Models, Animal, Humans, Lipids/chemistry/genetics, Male, Mice, Morinda/*chemistry, Seeds/chemistry, Sepsis/*drug therapy/microbiology/pathology/surgery, Staphylococcus aureus/drug effects/pathogenicityEnzymology
Phylogeny30141597[Identification and Antagonistic Properties of the Soil Streptomycete Streptomyces sp. 100].Biliavska LA, Efimenko TA, Efremenkova OV, Koziritska VY, Iutynska GAMikrobiol Z2016*Antibiosis, Fusarium, Pseudomonas, RNA, Ribosomal, 16S/genetics, Soil, *Soil Microbiology, Streptomyces/genetics/*physiology
Pathogenicity30345828Chemical constituents, in vitro antioxidant and antimicrobial properties of ethyl acetate extract obtained from Cytisus triflorus l'Her.Benabderrahmane W, Amrani A, Benaissa O, Lores M, Lamas JP, de Miguel T, Benayache F, Benayache SNat Prod Res10.1080/14786419.2018.15198162018Acetates/chemistry, Anti-Bacterial Agents/chemistry/*pharmacology, Antioxidants/administration & dosage/chemistry/*pharmacology, Cytisus/*chemistry, Dose-Response Relationship, Drug, Escherichia coli/drug effects, Flavonoids/analysis/chemistry, Lipid Peroxidation/drug effects, Microbial Sensitivity Tests, Molecular Structure, Phenols/analysis, Plant Components, Aerial/chemistry, Plant Extracts/chemistry/*pharmacology, Staphylococcus aureus/drug effects
Phylogeny30509938Genetic and Transcriptomic Analyses of Ciprofloxacin-Tolerant Staphylococcus aureus Isolated by the Replica Plating Tolerance Isolation System (REPTIS).Matsuo M, Hiramatsu M, Singh M, Sasaki T, Hishinuma T, Yamamoto N, Morimoto Y, Kirikae T, Hiramatsu KAntimicrob Agents Chemother10.1128/AAC.02019-182019Anti-Bacterial Agents/*pharmacology, Ciprofloxacin/*pharmacology, Drug Resistance, Bacterial/*genetics, GTP Pyrophosphokinase/genetics, Gene Expression Profiling/methods, Humans, Leucine-tRNA Ligase/genetics, Microbial Sensitivity Tests/*methods, Mupirocin/pharmacology, Staphylococcus aureus/*drug effects/*genetics/isolation & purificationPathogenicity
Metabolism30986911Study of the Lipid Profile of ATCC and Clinical Strains of Staphylococcus aureus in Relation to Their Antibiotic Resistance.Bisignano C, Ginestra G, Smeriglio A, La Camera E, Crisafi G, Franchina FA, Tranchida PQ, Alibrandi A, Trombetta D, Mondello L, Mandalari GMolecules10.3390/molecules240712762019Anti-Bacterial Agents/*pharmacology, Chromatography, Gas, Drug Resistance, Microbial, Fatty Acids/metabolism, Hydrophobic and Hydrophilic Interactions, Microbial Sensitivity Tests, Phospholipids/metabolism, Staphylococcus aureus/*drug effects/*metabolismPathogenicity
Pathogenicity31009250Antibacterial Effects of Phytic Acid against Foodborne Pathogens and Investigation of Its Mode of Action.Zhou QI, Zhao YU, Dang H, Tang Y, Zhang BJ Food Prot10.4315/0362-028X.JFP-18-4182019Anti-Bacterial Agents/pharmacology, *Bacteria/drug effects, Bacterial Adhesion/drug effects, *Food Microbiology, Microbial Sensitivity Tests, Microscopy, Electron, Scanning, *Phytic Acid/pharmacologyBiotechnology
Pathogenicity31365649Evaluating antimicrobial and antioxidant capacity of endemic Phlomis russeliana from Turkey and its antiproliferative effect on Human Caco-2 Cell Lines.Alpay M, Dulger G, Sahin IE, Dulger BAn Acad Bras Cienc10.1590/0001-37652019201804042019Anti-Bacterial Agents/isolation & purification/*pharmacology, Antioxidants/isolation & purification/*pharmacology, Caco-2 Cells, Candida albicans/*drug effects, Disk Diffusion Antimicrobial Tests, Gram-Negative Bacteria/classification/*drug effects, Gram-Positive Bacteria/classification/*drug effects, Humans, Phlomis/*chemistry, Plant Extracts/*pharmacology, TurkeyPhylogeny
Pathogenicity31614835Comparative In Vitro Evaluation of Antibacterial and Osteogenic Activity of Polysaccharide and Flavonoid Fractions Isolated from the leaves of Saussurea controversa.Khlusov I, Avdeeva E, Shupletsova V, Khaziakhmatova O, Litvinova L, Porokhova E, Reshetov Y, Zvereva I, Mushtovatova L, Karpova M, Guryev A, Sukhodolo I, Belousov MMolecules10.3390/molecules242036802019Anti-Bacterial Agents/chemistry/*pharmacology, Cell Differentiation/drug effects, Flavonoids/chemistry/*pharmacology, Humans, Mesenchymal Stem Cells/drug effects, Osteogenesis/drug effects, Plant Leaves/chemistry, Polysaccharides/chemistry/*pharmacology, Saussurea/*chemistryPhylogeny
Pathogenicity31623329The Antimicrobial and Antiviral Activity of Polyphenols from Almond (Prunus dulcis L.) Skin.Musarra-Pizzo M, Ginestra G, Smeriglio A, Pennisi R, Sciortino MT, Mandalari GNutrients10.3390/nu111023552019Animals, Anti-Infective Agents/*pharmacology, Antiviral Agents/*pharmacology, Chlorocebus aethiops, DNA, Viral/analysis, Herpesvirus 1, Human/drug effects/genetics, Microbial Sensitivity Tests, Plant Extracts/chemistry, Polyphenols/isolation & purification/*pharmacology, Prunus dulcis/*chemistry, Seeds/*chemistry, Staphylococcus aureus/drug effects, Vero Cells/virologyEnzymology
Pathogenicity32448814Potent Antibacterial Activity of Synthetic Peptides Designed from Salusin-beta and HIV-1 Tat(49-57).Kimura M, Kosuge K, Ko Y, Kurosaki N, Tagawa N, Kato I, Uchida YChem Pharm Bull (Tokyo)10.1248/cpb.c20-002092020Amino Acid Sequence, Anti-Bacterial Agents/*chemical synthesis/chemistry/pharmacology, Cell Membrane/drug effects, Escherichia coli/drug effects, HIV-1/metabolism, Humans, Intercellular Signaling Peptides and Proteins/*chemistry, Microbial Sensitivity Tests, Peptides/chemical synthesis/*chemistry/pharmacology, Staphylococcus aureus/drug effects, tat Gene Products, Human Immunodeficiency Virus/*chemistryMetabolism
Pathogenicity32589001Preparation, Antimicrobial Properties, and Cytotoxicity of Acrylic Resins Containing Poly(diallyldimethylammonium chloride).Dos Santos RLO, Sarra G, Lincopan N, Petri DFS, Aliaga J, Marques MM, Dias RB, Coto NP, Sugaya NN, Paula CRInt J Prosthodont10.11607/ijp.65062020*Acrylic Resins, *Anti-Bacterial Agents, Gram-Negative Bacteria, Gram-Positive Bacteria, Humans, Polyethylenes, Quaternary Ammonium Compounds
34219748Bacteriostatic impact of nanoscale zero-valent iron against pathogenic bacteria in the municipal wastewater.Sadek AH, Asker MS, Abdelhamid SABiologia (Bratisl)10.1007/s11756-021-00814-w2021
34714443The Ethyl Acetate Extract of the Marine Edible Gastropod Haliotis tuberculata coccinea: a Potential Source of Bioactive Compounds.Tortorella E, Giugliano R, De Troch M, Vlaeminck B, de Vicose GC, de Pascale DMar Biotechnol (NY)10.1007/s10126-021-10073-02021Acetates, Animals, *Bivalvia, *Gastropoda, *Methicillin-Resistant Staphylococcus aureus
34866130Anti-Biofilm Effects of Torilis japonica Ethanol Extracts against Staphylococcus aureus.Kim GS, Park CR, Kim JE, Kim HK, Kim BSJ Microbiol Biotechnol10.4014/jmb.2107.070532022Animals, Anti-Bacterial Agents/pharmacology, Biofilms, Ethanol/pharmacology, *Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Plant Extracts/pharmacology, Sheep, *Staphylococcal Infections/drug therapy, Staphylococcus aureus
Pathogenicity34994956Characterization and validation of an alternative reference bacterium Korean Pharmacopoeia Staphylococcus aureus strain.An YW, Choi YS, Yun MR, Choi C, Kim SYJ Microbiol10.1007/s12275-022-1335-52022Anti-Bacterial Agents/pharmacology, Bacterial Typing Techniques/methods, Drug Resistance, Bacterial, Humans, RNA, Ribosomal, 16S, Reference Standards, Republic of Korea, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods, Staphylococcal Infections/microbiology, Staphylococcus aureus/*classification/cytology/drug effects/*genetics, Whole Genome SequencingPhylogeny
Pathogenicity35049890Saccharobisindole, Neoasterric Methyl Ester, and 7-Chloro-4(1H)-quinolone: Three New Compounds Isolated from the Marine Bacterium Saccharomonospora sp.Kim S, Le TC, Han SA, Hillman PF, Hong A, Hwang S, Du YE, Kim H, Oh DC, Cha SS, Lee J, Nam SJ, Fenical WMar Drugs10.3390/md200100352021*Actinobacteria, Animals, Anti-Bacterial Agents/chemistry/*pharmacology, Aquatic Organisms, Bacillus subtilis/drug effects, Esters, Humans, Microbial Sensitivity Tests, Quinolones/chemistry/*pharmacologyPhylogeny
35206082Probiotic Effects and Metabolic Products of Enterococcus faecalis LD33 with Respiration Capacity.Jiao Y, Yang H, Shigwedha N, Zhang S, Liu F, Zhang LFoods10.3390/foods110406062022
35478884Development of structurally extended benzosiloxaboroles - synthesis and in vitro biological evaluation.Pacholak P, Krajewska J, Winska P, Dunikowska J, Gogowska U, Mierzejewska J, Durka K, Wozniak K, Laudy AE, Lulinski SRSC Adv10.1039/d1ra04127d2021
36090419Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity.Krajewska J, Nowicki K, Durka K, Marek-Urban PH, Winska P, Stepniewski T, Wozniak K, Laudy AE, Lulinski SRSC Adv10.1039/d2ra03910a2022
Phylogeny36289975In Silico Study for Algerian Essential Oils as Antimicrobial Agents against Multidrug-Resistant Bacteria Isolated from Pus Samples.Aouf A, Bouaouina S, Abdelgawad MA, Abourehab MAS, Farouk AAntibiotics (Basel)10.3390/antibiotics111013172022Pathogenicity
36404740Apis mellifera Venom Inhibits Bacterial and Fungal Pathogens in vitro.K Bakhiet E, A M Hussien H, Elshehaby MPak J Biol Sci10.3923/pjbs.2022.875.8842022Bees, Animals, *Antifungal Agents/pharmacology, Microbial Sensitivity Tests, Bacteria, Anti-Bacterial Agents/pharmacology, *Anti-Infective Agents/pharmacology, Escherichia coli

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20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
41865Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/17000
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68375Automatically annotated from API ID32STA
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.https://microbeatlas.org/MicrobeAtlas 1.0 beta
69480Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesPredictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)