Strain identifier

BacDive ID: 138128

Type strain: No

Species: Clostridioides difficile

Strain Designation: 545

Strain history: CIP <- 1996, J.P. Carlier, Inst. Pasteur, Paris, France: strain AIP 10133, Clostridium difficile C <- M. Delmée, Leuven, Belgium: strain 545

NCBI tax ID(s): 1496 (species)

For citation purpose refer to the digital object identifier (doi) of the current version.
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General

@ref: 39141

BacDive-ID: 138128

keywords: Bacteria, anaerobe, mesophilic

description: Clostridioides difficile 545 is an anaerobe, mesophilic bacterium of the family Peptostreptococcaceae.

NCBI tax id

  • NCBI tax id: 1496
  • Matching level: species

strain history

  • @ref: 39141
  • history: CIP <- 1996, J.P. Carlier, Inst. Pasteur, Paris, France: strain AIP 10133, Clostridium difficile C <- M. Delmée, Leuven, Belgium: strain 545

doi: 10.13145/bacdive138128.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Clostridia
  • order: Eubacteriales
  • family: Peptostreptococcaceae
  • genus: Clostridioides
  • species: Clostridioides difficile
  • full scientific name: Clostridioides difficile (Hall and O'Toole 1935) Lawson et al. 2016
  • synonyms

    @refsynonym
    20215Bacillus difficilis
    20215Peptoclostridium difficile
    20215Clostridium difficile

@ref: 39141

domain: Bacteria

phylum: Firmicutes

class: Clostridia

order: Eubacteriales

family: Peptostreptococcaceae

genus: Clostridioides

species: Clostridioides difficile

strain designation: 545

type strain: no

Culture and growth conditions

culture medium

@refnamegrowthcompositionlink
39141MEDIUM 20 - for Anaerobic bacteriayesAgar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)
39141CIP Medium 20yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=20

culture temp

@refgrowthtypetemperaturerange
39141positivegrowth37mesophilic
53852positivegrowth37mesophilic

Physiology and metabolism

oxygen tolerance

  • @ref: 53852
  • oxygen tolerance: anaerobe

fatty acid profile

  • fatty acids

    @reffatty acidpercentageECL
    53852C10:01.510
    53852C12:04.112
    53852C14:03.114
    53852C16:015.416
    53852C18:07.618
    53852C12:0 ISO1.311.608
    53852C13:0 ISO 2OH1.113.814
    53852C16:0 aldehyde514.949
    53852C16:0 iso2.215.626
    53852C16:1 ω7c8.815.819
    53852C16:1 ω9c615.774
    53852C17:0 CYCLO3.316.888
    53852C17:1 ISO I/C16:0 DMA1716.481
    53852C18:1 ISO H1.717.46
    53852C18:1 ω7c /12t/9t2.417.824
    53852C18:1 ω9c5.417.769
    53852C18:2 ω6,9c/C18:0 ANTE217.724
    53852C19:0 CYCLO ω9c3.718.87
    53852C19:1 ISO I5.418.473
    53852Unidentified1.516.108
    53852unknown 9.7301.89.73
  • type of FA analysis: whole cell analysis
  • method/protocol: CCUG

Isolation, sampling and environmental information

isolation

@refcountryorigin.countrycontinentsample type
39141BelgiumBELEurope
39141BelgiumBELEuropeHuman, Feces

Safety information

risk assessment

  • @ref: 39141
  • biosafety level: 2
  • biosafety level comment: Risk group (French classification)

External links

@ref: 39141

culture collection no.: CIP 104904, ATCC 43596, CCUG 37766

straininfo link

  • @ref: 94918
  • straininfo: 41930

literature

  • Pubmed-ID: 35500838
  • title: Activity of omadacycline in vitro against Clostridioides difficile and preliminary efficacy assessment in a hamster model of C. difficile-associated diarrhea.
  • authors: Leahy RG, Serio AW, Wright K, Traczewski MM, Tanaka SK
  • journal: J Glob Antimicrob Resist
  • DOI: 10.1016/j.jgar.2022.04.019
  • year: 2022

Reference

@idauthorstitledoi/urlcatalogue
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ10.1099/ijsem.0.004332
39141Curators of the CIPhttps://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20104904Collection of Institut Pasteur (CIP 104904)
53852Curators of the CCUGhttps://www.ccug.se/strain?id=37766Culture Collection University of Gothenburg (CCUG) (CCUG 37766)
94918Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.StrainInfo: A central database for resolving microbial strain identifiers10.60712/SI-ID41930.1