Strain identifier

BacDive ID: 135307

Type strain: No

Species: Lactobacillus acidophilus

Strain Designation: 43

Strain history: CIP <- 1992, F. Gasser, Inst. Pasteur, Paris, France: strain VPI 0324, Lactobacillus acidophilus, group A1 <- ATCC <- E.O. Jorda, Bacillus acidophilus <- L.F. Rettger: strain 43

NCBI tax ID(s): 1579 (species)

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General

@ref: 34391

BacDive-ID: 135307

keywords: 16S sequence, Bacteria, facultative anaerobe, mesophilic, Gram-positive, rod-shaped

description: Lactobacillus acidophilus 43 is a facultative anaerobe, mesophilic, Gram-positive bacterium that was isolated from Human, Human isolate.

NCBI tax id

  • NCBI tax id: 1579
  • Matching level: species

strain history

@refhistory
67770ATCC 314 <-- E. O. Jordan ("Bacillus acidophilus") <-- L. F. Rettger 43.
34391CIP <- 1992, F. Gasser, Inst. Pasteur, Paris, France: strain VPI 0324, Lactobacillus acidophilus, group A1 <- ATCC <- E.O. Jorda, Bacillus acidophilus <- L.F. Rettger: strain 43

doi: 10.13145/bacdive135307.20230509.8.1

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/bacillota
  • domain: Bacteria
  • phylum: Bacillota
  • class: Bacilli
  • order: Lactobacillales
  • family: Lactobacillaceae
  • genus: Lactobacillus
  • species: Lactobacillus acidophilus
  • full scientific name: Lactobacillus acidophilus (Moro 1900) Hansen and Mocquot 1970 (Approved Lists 1980)

  • synonyms

    • @ref: 20215
    • synonym: Bacillus acidophilus

@ref: 34391

domain: Bacteria

phylum: Firmicutes

class: Bacilli

order: Lactobacillales

family: Lactobacillaceae

genus: Lactobacillus

species: Lactobacillus acidophilus

strain designation: 43

type strain: no

Morphology

cell morphology

  • @ref: 34391
  • gram stain: positive
  • cell shape: rod-shaped
  • motility: no

Culture and growth conditions

culture medium

@refnamegrowthcompositionlink
34391MEDIUM 40- for Lactobacillus and LeuconostocyesDistilled water make up to (1000.000 ml);Man Rogosa Sharp agar (68.000 g)
34391CIP Medium 40yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=40

culture temp

@refgrowthtypetemperaturerange
34391positivegrowth37mesophilic
67770positivegrowth37mesophilic
34391positivegrowth37-45
34391nogrowth15psychrophilic

Physiology and metabolism

oxygen tolerance

  • @ref: 34391
  • oxygen tolerance: facultative anaerobe

metabolite utilization

@refmetaboliteutilization activitykind of utilization testedChebi-ID
68371Potassium 5-ketogluconate-builds acid from
68371Potassium 2-ketogluconate-builds acid from
68371gluconate-builds acid from24265
68371L-arabitol-builds acid from18403
68371D-arabitol-builds acid from18333
68371L-fucose-builds acid from18287
68371D-fucose-builds acid from28847
68371D-tagatose-builds acid from16443
68371D-lyxose-builds acid from62318
68371turanose-builds acid from32528
68371gentiobiose+builds acid from28066
68371xylitol-builds acid from17151
68371glycogen-builds acid from28087
68371starch-builds acid from28017
68371melezitose-builds acid from6731
68371inulin-builds acid from15443
68371trehalose-builds acid from27082
68371sucrose+builds acid from17992
68371melibiose-builds acid from28053
68371lactose+builds acid from17716
68371maltose+builds acid from17306
68371cellobiose+builds acid from17057
68371salicin+builds acid from17814
68371esculin+builds acid from4853
68371arbutin+builds acid from18305
68371amygdalin+builds acid from27613
68371N-acetylglucosamine+builds acid from59640
68371methyl alpha-D-glucopyranoside-builds acid from320061
68371methyl alpha-D-mannoside-builds acid from43943
68371D-sorbitol-builds acid from17924
68371D-mannitol-builds acid from16899
68371myo-inositol-builds acid from17268
68371galactitol-builds acid from16813
68371L-rhamnose-builds acid from62345
68371L-sorbose-builds acid from17266
68371D-mannose+builds acid from16024
68371D-fructose+builds acid from15824
68371D-glucose+builds acid from17634
68371D-galactose+builds acid from12936
68371methyl beta-D-xylopyranoside-builds acid from74863
68371ribitol-builds acid from15963
68371L-xylose-builds acid from65328
68371D-xylose-builds acid from65327
68371D-ribose-builds acid from16988
68371L-arabinose-builds acid from30849
68371D-arabinose-builds acid from17108
68371erythritol-builds acid from17113
68371glycerol-builds acid from17754
34391nitrate-reduction17632
34391nitrite-reduction16301
34391nitrate+respiration17632

enzymes

@refvalueactivityec
34391oxidase-
34391alcohol dehydrogenase-1.1.1.1
34391catalase-1.11.1.6
34391lysine decarboxylase-4.1.1.18
34391ornithine decarboxylase-4.1.1.17
68382alkaline phosphatase-3.1.3.1
68382esterase (C 4)+
68382esterase lipase (C 8)-
68382lipase (C 14)-
68382leucine arylamidase+3.4.11.1
68382valine arylamidase+
68382cystine arylamidase-3.4.11.3
68382trypsin-3.4.21.4
68382alpha-chymotrypsin-3.4.21.1
68382acid phosphatase-3.1.3.2
68382naphthol-AS-BI-phosphohydrolase+
68382alpha-galactosidase-3.2.1.22
68382beta-galactosidase+3.2.1.23
68382beta-glucuronidase-3.2.1.31
68382alpha-glucosidase+3.2.1.20
68382beta-glucosidase+3.2.1.21
68382N-acetyl-beta-glucosaminidase+3.2.1.52
68382alpha-mannosidase-3.2.1.24
68382alpha-fucosidase-3.2.1.51

API zym

@refControlAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
34391--+--++----+-+-+++--

API 50CHac

@refGLYERYDARALARARIBDXYLLXYLADOMDXGALGLUFRUMNESBERHADULINOMANSORMDMMDGNAGAMYARBESCSALCELMALLACMELSACTREINUMLZRAFAMDGLYGXLTGENTURLYXTAGDFUCLFUCDARLLARLGNT2KG5KG
34391---------++++--------++++++++-+---+/----+----------

Isolation, sampling and environmental information

isolation

  • @ref: 34391
  • sample type: Human, Human isolate

taxonmaps

  • @ref: 69479
  • File name: preview.99_1527.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_46;96_146;97_157;98_175;99_1527&stattab=map
  • Last taxonomy: Lactobacillus acidophilus
  • 16S sequence: AB690249
  • Sequence Identity:
  • Total samples: 40282
  • soil counts: 892
  • aquatic counts: 1233
  • animal counts: 37635
  • plant counts: 522

Safety information

risk assessment

  • @ref: 34391
  • biosafety level: 1
  • biosafety level comment: Risk group (French classification)

Sequence information

16S sequences

  • @ref: 67770
  • description: Lactobacillus acidophilus gene for 16S rRNA, partial sequence, strain: JCM 2121
  • accession: AB690249
  • length: 1507
  • database: ena
  • NCBI tax ID: 1579

External links

@ref: 34391

culture collection no.: CIP 103598, ATCC 314, JCM 2121

straininfo link

  • @ref: 92681
  • straininfo: 3196

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Metabolism19961357Viability and growth characteristics of Lactobacillus in soymilk supplemented with B-vitamins.Ewe JA, Wan-Abdullah WN, Liong MTInt J Food Sci Nutr10.3109/096374809033341632010Chromatography, High Pressure Liquid, Colony Count, Microbial, Dietary Supplements, *Food Microbiology, Hydrogen-Ion Concentration, Hydrolysis, Lactobacillus/*growth & development, Lactobacillus acidophilus/*growth & development, Microbial Viability, Oligosaccharides/metabolism, *Probiotics, Soy Milk/chemistry/*metabolism, *Soybeans, Vitamin B Complex/biosynthesis/*metabolism, alpha-Galactosidase/metabolismBiotechnology
Metabolism20338415Removal of cholesterol by lactobacilli via incorporation and conversion to coprostanol.Lye HS, Rusul G, Liong MTJ Dairy Sci10.3168/jds.2009-25742010Bifidobacterium/enzymology/*metabolism, Cell Membrane/chemistry/*metabolism, Cholestanol/*metabolism, Cholesterol/*metabolism, Cultured Milk Products/microbiology, Fatty Acids/analysis, Humans, Hypercholesterolemia/therapy, Lactobacillus/enzymology/*metabolism, Oxidoreductases/metabolism, Probiotics, SonicationEnzymology
Metabolism23433374Use of Lactobacillus acidophilus and Lactobacillus casei for a potential probiotic legume-based fermented product using pigeon pea (Cajanus cajan).Parra K, Ferrer M, Pinero M, Barboza Y, Medina LMJ Food Prot10.4315/0362-028X.JFP-12-1382013Animals, Cajanus/metabolism/*microbiology, Colony Count, Microbial, *Fermentation, Food Handling/*methods, Humans, Hydrogen-Ion Concentration, Lactobacillus acidophilus/growth & development/*metabolism, Lactobacillus casei/growth & development/*metabolism, Microbial Viability, Milk, ProbioticsPathogenicity
Metabolism25295259Cholesterol assimilation by Lactobacillus probiotic bacteria: an in vitro investigation.Tomaro-Duchesneau C, Jones ML, Shah D, Jain P, Saha S, Prakash SBiomed Res Int10.1155/2014/3803162014Acyl Coenzyme A/antagonists & inhibitors, Amidohydrolases/*metabolism, Cardiovascular Diseases/drug therapy/metabolism/pathology, Cholesterol/*metabolism, Culture Media, Humans, In Vitro Techniques, Lactobacillus plantarum/*metabolism, Probiotics/*metabolism/therapeutic useCultivation
Pathogenicity27837314Design and validation of an orally administrated active L. fermentum-L. acidophilus probiotic formulation using colorectal cancer Apc (Min/+) mouse model.Kahouli I, Malhotra M, Westfall S, Alaoui-Jamali MA, Prakash SAppl Microbiol Biotechnol10.1007/s00253-016-7885-x2016Animals, Antioxidants/*therapeutic use, Apoptosis/drug effects, Caco-2 Cells, Cadherins/biosynthesis, Carcinogenesis/*drug effects, Caspase 3/biosynthesis, Cell Extracts/*therapeutic use, Cell Line, Tumor, Cell Proliferation/drug effects, Cell Survival/drug effects, Colorectal Neoplasms/*prevention & control/therapy, Disease Models, Animal, Humans, Ki-67 Antigen/biosynthesis, Lactobacillus acidophilus/*metabolism, Lactobacillus fermentum/*metabolism, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Probiotics/*therapeutic use, beta Catenin/biosynthesisMetabolism
Enzymology29751685Inhibition of Insulin Degrading Enzyme and Insulin Degradation by UV-Killed Lactobacillus acidophilus.Neyazi N, Motevaseli E, Khorramizadeh MR, Mohammadi Farsani T, Nouri Z, Nasli Esfahani E, Ghahremani MHMed Sci (Basel)10.3390/medsci60200362018Metabolism

Reference

@idauthorstitledoi/urlcatalogue
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ10.1099/ijsem.0.004332
34391Curators of the CIPhttps://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20103598Collection of Institut Pasteur (CIP 103598)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68371Automatically annotated from API 50CH acid
68382Automatically annotated from API zym
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.MicrobeAtlas 1.0 betahttps://microbeatlas.org/
92681Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.StrainInfo: A central database for resolving microbial strain identifiers10.60712/SI-ID3196.1