Strain identifier
BacDive ID: 12531
Type strain:
Species: Prevotella intermedia
Strain Designation: B422
Strain history: <- DSM <- ATCC <- LV Holdeman, VPI 4197 <- S Finegold, B422
NCBI tax ID(s): 1122984 (strain), 28131 (species)
General
@ref: 8783
BacDive-ID: 12531
DSM-Number: 20706
keywords: genome sequence, 16S sequence, Bacteria, anaerobe, mesophilic, rod-shaped, human pathogen
description: Prevotella intermedia B422 is an anaerobe, mesophilic, rod-shaped human pathogen that was isolated from empyema.
NCBI tax id
NCBI tax id | Matching level |
---|---|
1122984 | strain |
28131 | species |
strain history
@ref | history |
---|---|
8783 | <- ATCC <- L.V. Holdeman, VPI 4197 <- S. Finegold, B422 |
67770 | K. Okamoto <-- ATCC 25611 <-- L. V. Holdeman VPI 4197 <-- S. Finegold B422. |
67771 | <- DSM <- ATCC <- LV Holdeman, VPI 4197 <- S Finegold, B422 |
doi: 10.13145/bacdive12531.20230509.8.1
Name and taxonomic classification
LPSN
- @ref: 20215
- description: domain/bacteria
- keyword: phylum/bacteroidota
- domain: Bacteria
- phylum: Bacteroidota
- class: Bacteroidia
- order: Bacteroidales
- family: Prevotellaceae
- genus: Prevotella
- species: Prevotella intermedia
- full scientific name: Prevotella intermedia (Holdeman and Moore 1970) Shah and Collins 1990
synonyms
@ref synonym 20215 Bacteroides melaninogenicus subsp. intermedius 20215 Bacteroides intermedius
@ref: 8783
domain: Bacteria
phylum: Bacteroidetes
class: Bacteroidia
order: Bacteroidales
family: Prevotellaceae
genus: Prevotella
species: Prevotella intermedia
full scientific name: Prevotella intermedia (Holdeman and Moore 1970) Shah and Collins 1990 emend. Hahnke et al. 2016
strain designation: B422
type strain: yes
Morphology
cell morphology
@ref | cell shape | gram stain | confidence |
---|---|---|---|
67771 | rod-shaped | ||
67771 | negative | ||
69480 | negative | 99.998 |
colony morphology
- @ref: 8783
- incubation period: 1-2 days
Culture and growth conditions
culture medium
@ref | name | growth | link | composition |
---|---|---|---|---|
8783 | COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) | yes | https://mediadive.dsmz.de/medium/693 | Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base |
8783 | PYG MEDIUM (MODIFIED) (DSMZ Medium 104) | yes | https://mediadive.dsmz.de/medium/104 | Name: PYG MEDIUM (modified) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water |
culture temp
@ref | growth | type | temperature | range |
---|---|---|---|---|
8783 | positive | growth | 37 | mesophilic |
67770 | positive | growth | 37 | mesophilic |
67771 | positive | growth | 37 | mesophilic |
Physiology and metabolism
oxygen tolerance
@ref | oxygen tolerance | confidence |
---|---|---|
8783 | anaerobe | |
67771 | anaerobe | |
69480 | anaerobe | 99.599 |
spore formation
@ref | spore formation | confidence |
---|---|---|
69481 | no | 100 |
69480 | no | 99.998 |
metabolite utilization
@ref | Chebi-ID | metabolite | utilization activity | kind of utilization tested |
---|---|---|---|---|
68367 | 16634 | raffinose | + | builds acid from |
68367 | 16024 | D-mannose | + | builds acid from |
68367 | 17057 | cellobiose | - | builds acid from |
68367 | 5291 | gelatin | + | hydrolysis |
68367 | 17306 | maltose | + | builds acid from |
68367 | 17992 | sucrose | + | builds acid from |
68367 | 17716 | lactose | - | builds acid from |
68367 | 17634 | D-glucose | + | builds acid from |
68367 | 16199 | urea | - | hydrolysis |
68367 | 27897 | tryptophan | + | energy source |
68380 | 16199 | urea | - | hydrolysis |
68380 | 29016 | arginine | - | hydrolysis |
68380 | 29985 | L-glutamate | - | degradation |
68380 | 17632 | nitrate | - | reduction |
metabolite production
- @ref: 68367
- Chebi-ID: 35581
- metabolite: indole
- production: yes
metabolite tests
- @ref: 68367
- Chebi-ID: 35581
- metabolite: indole
- indole test: +
enzymes
@ref | value | activity | ec |
---|---|---|---|
68380 | glycin arylamidase | - | |
68380 | alanine arylamidase | + | 3.4.11.2 |
68380 | tyrosine arylamidase | - | |
68380 | pyrrolidonyl arylamidase | - | 3.4.19.3 |
68380 | leucine arylamidase | - | 3.4.11.1 |
68380 | phenylalanine arylamidase | - | |
68380 | leucyl glycin arylamidase | + | 3.4.11.1 |
68380 | alkaline phosphatase | + | 3.1.3.1 |
68380 | glutamate decarboxylase | - | 4.1.1.15 |
68380 | N-acetyl-beta-glucosaminidase | - | 3.2.1.52 |
68380 | beta-glucuronidase | - | 3.2.1.31 |
68380 | alpha-arabinosidase | - | 3.2.1.55 |
68380 | beta-glucosidase | - | 3.2.1.21 |
68380 | beta-Galactosidase 6-phosphate | - | |
68380 | beta-galactosidase | - | 3.2.1.23 |
68380 | alpha-galactosidase | - | 3.2.1.22 |
68380 | arginine dihydrolase | - | 3.5.3.6 |
68380 | urease | - | 3.5.1.5 |
68367 | catalase | - | 1.11.1.6 |
68367 | gelatinase | + | |
68367 | urease | - | 3.5.1.5 |
fatty acid profile
fatty acids
@ref fatty acid percentage ECL 47910 C14:0 1.8 14 47910 C16:0 7.8 16 47910 C18:0 3.2 18 47910 C13:0 iso 1.7 12.612 47910 C14:0 ISO 12.4 13.618 47910 C15:0 ANTEISO 17.9 14.711 47910 C15:0 ISO 10.7 14.621 47910 C16:0 iso 2.5 15.626 47910 C17:0 iso 0.9 16.629 47910 C17:0 iso 3OH 8.5 18.161 47910 C18:2 ω6,9c/C18:0 ANTE 32.6 17.724 - type of FA analysis: whole cell analysis
- method/protocol: CCUG
API 20A
@ref | IND | URE | GLU | MAN | LAC | SAC | MAL | SAL | XYL | ARA | GEL | ESC | GLY | CEL | MNE | MLZ | RAF | SOR | RHA | TRE | CAT |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
8783 | + | - | + | + | - | + | + | + | + | + | + | + | + | - | + | + | + | + | + | + | - |
8783 | + | - | + | - | - | + | + | - | - | - | + | - | - | - | + | - | + | - | - | - |
API rID32A
@ref | URE | ADH Arg | alpha GAL | beta GAL | beta GP | alpha GLU | beta GLU | alpha ARA | beta GUR | beta NAG | MNE | RAF | GDC | alpha FUC | NIT | IND | PAL | ArgA | ProA | LGA | PheA | LeuA | PyrA | TyrA | AlaA | GlyA | HisA | GGA | SerA |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
8783 | - | - | - | - | - | + | - | - | - | - | - | - | - | + | - | + | + | + | +/- | + | - | - | - | - | + | - | +/- | + | - |
8783 | - | - | - | - | - | + | - | - | - | - | +/- | +/- | - | + | - | + | + | + | - | + | - | - | - | - | + | - | - | + | - |
47910 | - | - | - | - | - | + | - | - | - | - | - | - | - | + | - | - | + | + | - | + | - | - | - | - | + | - | + | + | - |
8783 | - | - | - | - | - | + | - | - | - | - | - | +/- | - | + | - | + | + | +/- | - | + | - | - | - | - | + | - | - | +/- | - |
8783 | - | - | - | - | - | + | - | - | - | - | - | +/- | - | - | - | + | + | - | - | + | - | - | - | - | + | - | - | + | - |
8783 | - | - | - | - | - | + | - | - | - | - | - | - | - | - | - | - | + | + | - | + | - | - | - | - | + | - | - | - | - |
8783 | - | - | - | - | - | + | - | - | - | - | - | +/- | - | - | - | + | + | + | - | + | - | - | - | - | + | - | - | + | - |
8783 | - | - | - | - | - | +/- | - | - | - | - | - | - | - | - | - | - | + | + | - | + | - | - | - | - | + | - | - | +/- | + |
Isolation, sampling and environmental information
isolation
@ref | sample type |
---|---|
8783 | empyema |
47910 | Empyema |
67770 | Empyema |
67771 | From empyema |
isolation source categories
- Cat1: #Host Body Product
- Cat2: #Fluids
taxonmaps
- @ref: 69479
- File name: preview.99_2089.png
- url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_295;96_1148;97_1348;98_1632;99_2089&stattab=map
- Last taxonomy: Prevotella intermedia subclade
- 16S sequence: X73965
- Sequence Identity:
- Total samples: 66903
- soil counts: 1452
- aquatic counts: 1863
- animal counts: 62951
- plant counts: 637
Safety information
risk assessment
- @ref: 8783
- pathogenicity human: yes
- pathogenicity animal: yes
- biosafety level: 2
- biosafety level comment: Risk group (German classification)
Sequence information
16S sequences
@ref | description | accession | length | database | NCBI tax ID |
---|---|---|---|---|---|
20218 | Prevotella intermedia 16S-23S ribosomal RNA intergenic spacer, partial sequence | AF385927 | 431 | ena | 1122984 |
20218 | Prevotella intermedia strain ATCC 25611 16S ribosomal RNA gene, partial sequence | AF414821 | 1364 | ena | 1122984 |
20218 | Prevotella intermedia ATCC 25611 16S ribosomal RNA gene, complete sequence | L16468 | 1473 | ena | 28131 |
20218 | P.intermedia gene for 16S rRNA | X73965 | 1459 | ena | 1122984 |
8783 | Prevotella intermedia strain ATCC 25611 16S ribosomal RNA gene, partial sequence | FJ792535 | 1370 | ena | 1122984 |
67770 | Prevotella intermedia gene for 16S ribosomal RNA, partial sequence, strain: JCM 11150 | AB547687 | 1380 | ena | 1122984 |
Genome sequences
@ref | description | accession | assembly level | database | NCBI tax ID |
---|---|---|---|---|---|
66792 | Prevotella intermedia ATCC 25611 = DSM 20706 | GCA_001953955 | complete | ncbi | 1122984 |
66792 | Prevotella intermedia ATCC 25611 | 1122984.4 | wgs | patric | 1122984 |
66792 | Prevotella intermedia ATCC 25611 = DSM 20706 strain ATCC 25611 | 1122984.13 | complete | patric | 1122984 |
66792 | Prevotella intermedia ATCC 25611 [PRJNA169798] | 1122984.7 | wgs | patric | 1122984 |
66792 | Prevotella intermedia strain NCTC13070 | 28131.49 | wgs | patric | 28131 |
66792 | Prevotella intermedia strain strain 17 | 28131.7 | complete | patric | 28131 |
66792 | Prevotella intermedia ATCC 25611 | 2515154173 | draft | img | 1122984 |
66792 | Prevotella intermedia ATCC 25611 | 2816332597 | complete | img | 1122984 |
66792 | Prevotella intermedia NCTC 13070 | 2903615608 | draft | img | 28131 |
66792 | Prevotella intermedia DSM 20706 | 2523231016 | draft | img | 1122984 |
67770 | Prevotella intermedia ATCC 25611 = DSM 20706 | GCA_000519165 | scaffold | ncbi | 1122984 |
67771 | Prevotella intermedia ATCC 25611 = DSM 20706 | GCA_000439065 | scaffold | ncbi | 1122984 |
67771 | Prevotella intermedia NCTC13070 | GCA_900455005 | contig | ncbi | 28131 |
GC content
@ref | GC-content | method |
---|---|---|
8783 | 43.3 | sequence analysis |
67770 | 44.2 | high performance liquid chromatography (HPLC) |
67771 | 43.3 | genome sequence analysis |
Genome-based predictions
predictions
trait | prediction | confidence | training_data |
---|---|---|---|
spore-forming | no | 100 | no |
flagellated | no | 97.282 | no |
gram-positive | no | 97.021 | yes |
anaerobic | yes | 98.913 | no |
halophile | no | 85.072 | no |
spore-forming | no | 96.868 | no |
glucose-util | yes | 81.858 | no |
aerobic | no | 98.358 | yes |
thermophile | no | 97.534 | yes |
motile | no | 92.134 | no |
glucose-ferment | yes | 53.022 | no |
External links
@ref: 8783
culture collection no.: DSM 20706, ATCC 25611, KCTC 15693, CCUG 24041, JCM 7365, JCM 12248, VPI 4197, JCM 11150, BCRC 14416, CIP 103682, NCTC 13070, CIP 101222, KCTC 3692
straininfo link
- @ref: 81750
- straininfo: 38613
literature
topic | Pubmed-ID | title | authors | journal | DOI | year | mesh | topic2 |
---|---|---|---|---|---|---|---|---|
Phylogeny | 1390107 | Biochemical and chemical studies on strains designated Prevotella intermedia and proposal of a new pigmented species, Prevotella nigrescens sp. nov. | Shah HN, Gharbia SE | Int J Syst Bacteriol | 10.1099/00207713-42-4-542 | 1992 | Bacterial Typing Techniques, Bacteroides/*classification/genetics/metabolism, Cellobiose/metabolism, Culture Media, DNA, Bacterial/chemistry, Fermentation, Nucleic Acid Hybridization, Phenotype, Pigmentation, Xylans/metabolism | Metabolism |
Phylogeny | 1528627 | Phenotypic characteristics and DNA relatedness in Prevotella intermedia and similar organisms. | Fukushima H, Moroi H, Inoue J, Onoe T, Ezaki T, Yabuuchi E, Leung KP, Walker CB, Clark WB, Sagawa H | Oral Microbiol Immunol | 10.1111/j.1399-302x.1992.tb00023.x | 1992 | Bacteroides/*classification/*genetics, DNA Probes, DNA, Bacterial/analysis, Humans, Nucleic Acid Hybridization, Periodontal Diseases/microbiology, Phenotype, Saliva/microbiology | Pathogenicity |
Phylogeny | 1920011 | Isolation and purification of bacteriocin from Prevotella intermedia (Bacteroides intermedius). | Takada K, Hirasawa M, Ikeda T | J Periodontol | 10.1902/jop.1991.62.7.439 | 1991 | Adult, Antibiosis, Bacteriocins/*isolation & purification/pharmacology, Bacteroides/classification/*metabolism, Colony Count, Microbial, Culture Media, Fusobacterium nucleatum/drug effects, Gingival Crevicular Fluid/microbiology, Humans, Molecular Weight, Periodontitis/microbiology | Pathogenicity |
Pathogenicity | 2134944 | [Mitogenic activity of lipopolysaccharide from Bacteroides intermedius against C3H/HeJ mice spleen cells]. | Yamamoto M, Ono K, Mochizuki S, Nishihara Y, Makimura M, Otake S | Nichidai Koko Kagaku | 1990 | Animals, *Bacteroides, Cell Division/drug effects, Cells, Cultured, *Lipopolysaccharides, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, Mitogens/*pharmacology, Polymyxin B/pharmacology, Spleen/cytology/*drug effects, Thymus Gland/cytology/drug effects | ||
Metabolism | 2562264 | [Effects of endotoxins from periodontopathic bacteria on the collagen metabolism of cultured normal human gingival fibroblasts]. | Tagata Y | Nihon Shishubyo Gakkai Kaishi | 10.2329/perio.31.755 | 1989 | Bacteroides, Collagen/*metabolism, Endotoxins/*pharmacokinetics, Fibroblasts/metabolism, Gingiva/cytology, Humans, Microbial Collagenase/metabolism, Periodontal Diseases/microbiology | Pathogenicity |
Pathogenicity | 2626166 | [Toxicity of Bacteroides intermedius surface extracts against mouse splenic lymphocyte]. | Kuroki T, Kato H, Nishihara Y, Nakagawa S, Makimura M, Otake S | Nichidai Koko Kagaku | 1989 | Animals, Bacterial Proteins/*toxicity, *Bacteroides, Cell Line, Lymphocytes/*drug effects, Membrane Proteins/*toxicity, Mice | ||
Pathogenicity | 2640314 | Surface appendages, hemagglutination, and adherence to human epithelial cells of Bacteroides intermedius. | Leung KP, Fukushima H, Sagawa H, Walker CB, Clark WB | Oral Microbiol Immunol | 10.1111/j.1399-302x.1989.tb00253.x | 1989 | Animals, *Bacterial Adhesion, Bacteroides/physiology/*ultrastructure, Cell Membrane/*ultrastructure, Epithelial Cells, *Hemagglutination, Humans, Mouth Mucosa/cytology | |
Phylogeny | 2902111 | The use of whole-cell DNA probes for the identification of Bacteroides intermedius isolates in a dot blot assay. | Moncla BJ, Strockbine L, Braham P, Karlinsey J, Roberts MC | J Dent Res | 10.1177/00220345880670100401 | 1988 | Bacteroides/*classification/genetics/isolation & purification, *DNA Probes, Nucleic Acid Hybridization, Prevotella melaninogenica/*classification/genetics/isolation & purification, Sequence Homology, Nucleic Acid, Species Specificity | Enzymology |
Pathogenicity | 7560233 | Effect of periodontal treatments on serum IgG antibody titers against periodontopathic bacteria. | Horibe M, Watanabe H, Ishikawa I | J Clin Periodontol | 10.1111/j.1600-051x.1995.tb00798.x | 1995 | Adult, Aggregatibacter actinomycetemcomitans/immunology, Alveolar Bone Loss/microbiology/surgery/therapy, Antibodies, Bacterial/*blood, Bacteria/*immunology, Capnocytophaga/immunology, Dental Scaling, Eikenella corrodens/immunology, Female, Fusobacterium nucleatum/immunology, Humans, Immunoglobulin G/*blood, Male, Middle Aged, Periodontal Pocket/microbiology/surgery/therapy, Periodontitis/*microbiology/surgery/*therapy, Porphyromonas gingivalis/immunology, Prevotella/immunology, Prevotella intermedia/immunology, Root Planing | |
Enzymology | 7796488 | Properties of alkaline phosphatase in the gingival crevicular fluid. | Kina JR, Yoshida N, Goseki M, Sasaki S, Ishikawa I | Bull Tokyo Med Dent Univ | 1995 | Aged, Alkaline Phosphatase/*chemistry/metabolism, Electrophoresis, Enzyme Activation, Female, Gingival Crevicular Fluid/*enzymology, Humans, Isoenzymes/*chemistry/metabolism, Male, Middle Aged, Periodontitis/enzymology | Metabolism | |
Pathogenicity | 8188371 | Immunobiological activities of a 55-kilodalton cell surface protein of Prevotella intermedia ATCC 25611. | Matsushita K, Nagaoka S, Arakaki R, Kawabata Y, Iki K, Kawagoe M, Takada H | Infect Immun | 10.1128/iai.62.6.2459-2469.1994 | 1994 | Amino Acid Sequence, Animals, Antigens, Surface/immunology, Bacterial Proteins/chemistry/*immunology/pharmacology, Bacteroides/*immunology, Cell Line, Cytokines/biosynthesis, Female, Humans, Mice, Mice, Inbred BALB C, Mice, Inbred C3H, Molecular Sequence Data, Molecular Weight | Genetics |
Metabolism | 9345789 | Fermentation product analysis in the identification of black-pigmented bacteria from periodontitis. | Takada K, Hirasawa M | Microbios | 1997 | Antibodies, Bacterial/analysis/immunology, Antigens, Bacterial/analysis/immunology, Bacteriological Techniques, Chromatography, Gas, Culture Media/*analysis/metabolism, Electrophoresis, Polyacrylamide Gel, Fatty Acids/*analysis/metabolism, Fermentation, Gram-Negative Anaerobic Bacteria/growth & development/immunology/*metabolism, Humans, Immunodiffusion, Periodontitis/*microbiology | Enzymology | |
Pathogenicity | 9353030 | A novel component different from endotoxin extracted from Prevotella intermedia ATCC 25611 activates lymphoid cells from C3H/HeJ mice and gingival fibroblasts from humans. | Iki K, Kawahara K, Sawamura S, Arakaki R, Sakuta T, Sugiyama A, Tamura H, Sueda T, Hamada S, Takada H | Infect Immun | 10.1128/iai.65.11.4531-4538.1997 | 1997 | Adjuvants, Immunologic/*analysis, Animals, Cytokines/biosynthesis, Fibroblasts/drug effects/metabolism, Gingiva/cytology, Glycoproteins/*analysis/pharmacology, Humans, Lipopolysaccharides/pharmacology, *Lymphocyte Activation, Mice, Mice, Inbred C3H, Polymyxin B/pharmacology, Prevotella intermedia/*chemistry | Metabolism |
Pathogenicity | 9354029 | Anti-bacterial action of onion (Allium cepa L.) extracts against oral pathogenic bacteria. | Kim JH | J Nihon Univ Sch Dent | 10.2334/josnusd1959.39.136 | 1997 | 1-Butanol/chemistry, Acetic Acid, Adult, Alkalies/pharmacology, Anti-Bacterial Agents/analysis/antagonists & inhibitors/*pharmacology, Cellulose, Chromatography, Thin Layer, Culture Media, Cysteine/pharmacology, Dental Caries/microbiology, Humans, Indicators and Reagents, Ninhydrin, *Onions/chemistry, Periodontitis/microbiology, Plant Extracts/analysis/antagonists & inhibitors/*pharmacology, Porphyromonas gingivalis/*drug effects, Prevotella intermedia/*drug effects, Solvents/chemistry, Steam, Streptococcus mutans/*drug effects, Streptococcus sobrinus/*drug effects, Time Factors | Cultivation |
Pathogenicity | 9467379 | Acid tolerance response and survival by oral bacteria. | Svensater G, Larsson UB, Greif EC, Cvitkovitch DG, Hamilton IR | Oral Microbiol Immunol | 10.1111/j.1399-302x.1997.tb00390.x | 1997 | Acids/*metabolism, Actinomyces/growth & development/*physiology, Adaptation, Biological, Culture Media/chemistry, Drug Tolerance, Humans, Hydrogen-Ion Concentration, Lactobacillus/growth & development/*physiology, Mouth/*microbiology, Neisseria/growth & development, Prevotella intermedia/growth & development, Streptococcus/growth & development/*physiology | Metabolism |
Phylogeny | 9542074 | Biochemical and genetic characterization of a Prevotella intermedia/nigrescens-like organism. | Kononen E, Matto J, Vaisanen-Tunkelrott ML, Frandsen EV, Helander I, Asikainen S, Finegold SM, Jousimies-Somer H | Int J Syst Bacteriol | 10.1099/00207713-48-1-39 | 1998 | Bacterial Proteins/analysis, Classification, DNA, Bacterial/analysis, Electrophoresis, Genetic Heterogeneity, Glutamate Dehydrogenase/analysis, Immunoglobulin A/metabolism, Malate Dehydrogenase/analysis, Oligonucleotide Probes, Polymerase Chain Reaction, Prevotella intermedia/classification/*enzymology/*genetics, Species Specificity, beta-Lactamases/metabolism | Enzymology |
Enzymology | 9654126 | Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia. | Ansai T, Awano S, Chen X, Fuchi T, Arimoto T, Akifusa S, Takehara T | FEBS Lett | 10.1016/s0014-5793(98)00514-6 | 1998 | Alkaline Phosphatase/chemistry/isolation & purification/*metabolism, Amino Acid Sequence, Chromatography, Gel, Chromatography, Ion Exchange, Electrophoresis, Polyacrylamide Gel, Enzyme Stability, Hot Temperature, Molecular Sequence Data, Peptide Fragments/chemistry, Prevotella intermedia/*enzymology, Protein Tyrosine Phosphatases/isolation & purification/*metabolism, Sequence Alignment, Sequence Homology, Amino Acid, Substrate Specificity, Thermodynamics | Phylogeny |
Pathogenicity | 9719033 | Dual regulatory effects of interferon-alpha, -beta, and -gamma on interleukin-8 gene expression by human gingival fibroblasts in culture upon stimulation with lipopolysaccharide from Prevotella intermedia, interleukin-1alpha, or tumor necrosis factor-alpha. | Sakuta T, Tokuda M, Tamura M, Jimi E, Ikebe T, Koba T, Nagaoka S, Takada H | J Dent Res | 10.1177/00220345980770080701 | 1998 | Blotting, Northern, Cells, Cultured, Child, Enzyme-Linked Immunosorbent Assay, Fibroblasts/drug effects/metabolism, Gene Expression Regulation, Gingiva/cytology/*drug effects/metabolism, Humans, Interferon-alpha/pharmacology, Interferon-beta/pharmacology, Interferon-gamma/pharmacology, Interferons/*pharmacology, Interleukin-1/pharmacology, Interleukin-8/*biosynthesis/genetics, Lipopolysaccharides/antagonists & inhibitors/*pharmacology, Male, NF-kappa B/physiology, Prevotella intermedia/chemistry, Protein Synthesis Inhibitors/pharmacology, RNA, Messenger/analysis, Recombinant Proteins/pharmacology, Tosylphenylalanyl Chloromethyl Ketone/pharmacology, Tumor Necrosis Factor-alpha/pharmacology, Up-Regulation | Metabolism |
Phylogeny | 10074526 | Use of PCR and sodium dodecyl sulfate-polyacrylamide gel electrophoresis techniques for differentiation of Prevotella intermedia sensu stricto and Prevotella nigrescens. | Premaraj T, Kato N, Fukui K, Kato H, Watanabe K | J Clin Microbiol | 10.1128/JCM.37.4.1057-1061.1999 | 1999 | *Bacterial Typing Techniques, Base Sequence, DNA Primers/genetics, Electrophoresis, Polyacrylamide Gel/*methods, Evaluation Studies as Topic, Humans, Polymerase Chain Reaction/*methods, Prevotella/*classification/*genetics/isolation & purification, Prevotella intermedia/*classification/*genetics/isolation & purification, RNA, Bacterial/genetics, RNA, Ribosomal, 16S/genetics, Reproducibility of Results, Sodium Dodecyl Sulfate, Species Specificity | Enzymology |
Phylogeny | 10559178 | Isolation, cloning, and expression of an acid phosphatase containing phosphotyrosyl phosphatase activity from Prevotella intermedia. | Chen X, Ansai T, Awano S, Iida T, Barik S, Takehara T | J Bacteriol | 10.1128/JB.181.22.7107-7114.1999 | 1999 | Acid Phosphatase/chemistry/*genetics/*isolation & purification/metabolism, Amino Acid Sequence, Base Sequence, Cloning, Molecular, Molecular Sequence Data, Phosphorylation, Phylogeny, Prevotella intermedia/*enzymology/genetics, Protein Tyrosine Phosphatases/chemistry/*genetics/*metabolism, Recombinant Proteins/metabolism, Sequence Analysis, DNA | Enzymology |
Phylogeny | 10635221 | Survey for collagenase gene prtC in Porphyromonas gingivalis and Porphyromonas endodontalis isolated from endodontic infections. | Odell LJ, Baumgartner JC, Xia T, David LL | J Endod | 10.1016/S0099-2399(99)80379-3 | 1999 | *Bacterial Proteins, Bacterial Typing Techniques, Bacteroidaceae Infections/microbiology, Collagenases/*genetics, DNA, Bacterial/genetics, Dental Pulp Cavity/microbiology, Dental Pulp Diseases/*microbiology, *Genes, Bacterial, Humans, Microbial Collagenase/*genetics, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Porphyromonas/classification/*enzymology/*genetics, Porphyromonas gingivalis/classification/enzymology/genetics, RNA, Ribosomal, 16S/genetics | Pathogenicity |
Pathogenicity | 10726523 | Inflammatory cytokine production and specific antibody responses to lipopolysaccharide from endodontopathic black-pigmented bacteria in patients with multilesional periapical periodontitis. | Matsushita K, Tajima T, Tomita K, Takada H, Nagaoka S, Torii M | J Endod | 10.1016/S0099-2399(99)80299-4 | 1999 | Adult, Antibodies, Bacterial/biosynthesis/blood, Case-Control Studies, Culture Media, Escherichia coli/chemistry/immunology, Fusobacterium nucleatum/chemistry/immunology, Humans, Interleukin-1/biosynthesis, Interleukin-6/biosynthesis, Interleukin-8/biosynthesis, Interleukins/*biosynthesis, Lipopolysaccharides/*immunology, Periapical Periodontitis/blood/*immunology/metabolism/*microbiology, Porphyromonas/chemistry/immunology, Prevotella intermedia/chemistry/immunology | Cultivation |
Metabolism | 11447173 | Monocytic cell activation by Nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2. | Sugawara S, Yang S, Iki K, Hatakeyama J, Tamai R, Takeuchi O, Akashi S, Espevik T, Akira S, Takada H | Infect Immun | 10.1128/IAI.69.8.4951-4957.2001 | 2001 | Acidic Glycosphingolipids/metabolism, *Acute-Phase Proteins, Animals, Antibodies, Monoclonal/metabolism/pharmacology, Bacterial Proteins/*metabolism, Calcitriol/analogs & derivatives/pharmacology, Carrier Proteins/metabolism, *Drosophila Proteins, Glycoproteins/*metabolism, Interleukin-8/biosynthesis, Lipopolysaccharide Receptors/biosynthesis, Lipopolysaccharides/pharmacology, Macrophages, Peritoneal/metabolism, Membrane Glycoproteins/biosynthesis/*metabolism, Mice, Mice, Inbred C3H, Mice, Knockout, Monocytes/drug effects/immunology/metabolism, Prevotella intermedia/*metabolism, Receptors, Cell Surface/biosynthesis/*metabolism, Toll-Like Receptor 2, Toll-Like Receptor 4, Toll-Like Receptors, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha/biosynthesis | Pathogenicity |
Pathogenicity | 12479628 | In vitro effect of laser irradiation on cementum-bound endotoxin isolated from periodontally diseased roots. | Liu CM, Shyu YC, Pei SC, Lan WH, Hou LT | J Periodontol | 10.1902/jop.2002.73.11.1260 | 2002 | Adult, Aggregatibacter actinomycetemcomitans/chemistry, Bacteroides/chemistry, Chi-Square Distribution, Dental Cementum/*microbiology, Endotoxins/*radiation effects, Humans, In Vitro Techniques, Interleukin-1/biosynthesis, *Laser Therapy, Limulus Test, Monocytes/metabolism, Neodymium, Periodontitis/*microbiology/*therapy, Porphyromonas gingivalis/chemistry, Statistics, Nonparametric, Treatment Failure | Metabolism |
Metabolism | 12728301 | Cleavage of CD14 and LBP by a protease from Prevotella intermedia. | Deschner J, Singhal A, Long P, Liu CC, Piesco N, Agarwal S | Arch Microbiol | 10.1007/s00203-003-0548-1 | 2003 | *Acute-Phase Proteins, Animals, Carrier Proteins/*metabolism, Cells, Cultured, Cysteine Endopeptidases/analysis/*metabolism, Cysteine Proteinase Inhibitors/metabolism, Electrophoresis, Polyacrylamide Gel, Humans, Lipopolysaccharide Receptors/*metabolism, Lipopolysaccharides/metabolism, *Membrane Glycoproteins, Mice, Monocytes/metabolism, Prevotella intermedia/*enzymology/metabolism, Time Factors, U937 Cells | Enzymology |
Enzymology | 12753473 | Purification and partial characterization of a dipeptidyl peptidase from Prevotella intermedia. | Shibata Y, Miwa Y, Hirai K, Fujimura S | Oral Microbiol Immunol | 10.1034/j.1399-302x.2003.00057.x | 2003 | Amino Acid Sequence, Bacterial Proteins/isolation & purification/metabolism, Dipeptidyl Peptidase 4/*isolation & purification/metabolism, Electrophoresis, Polyacrylamide Gel, Hydrogen-Ion Concentration, Molecular Weight, Prevotella intermedia/*enzymology/isolation & purification, Virulence Factors | Phylogeny |
Enzymology | 12753913 | Chemical structure and immunobiological activity of lipid A from Prevotella intermedia ATCC 25611 lipopolysaccharide. | Hashimoto M, Asai Y, Tamai R, Jinno T, Umatani K, Ogawa T | FEBS Lett | 10.1016/s0014-5793(03)00414-9 | 2003 | Animals, Cells, Cultured, Interleukin-6/biosynthesis, Lipid A/*chemistry/isolation & purification/*pharmacology, Mass Spectrometry, Mice, Mice, Inbred C3H, NF-kappa B/metabolism, Nuclear Magnetic Resonance, Biomolecular, Prevotella intermedia/*chemistry | Phylogeny |
Pathogenicity | 12937592 | Coronal microleakage assessed by polymicrobial markers. | Britto LR, Grimaudo NJ, Vertucci FJ | J Contemp Dent Pract | 1526-3711-112 | 2003 | Analysis of Variance, Biomarkers, Dental Leakage/*microbiology/prevention & control, Dental Pulp Cavity/*microbiology, Humans, Prevotella intermedia/isolation & purification/physiology, *Root Canal Filling Materials, Root Canal Obturation/*methods, Saliva/microbiology, Saliva, Artificial, Statistics, Nonparametric, Streptococcus/isolation & purification/physiology, Tooth Crown/microbiology, Tooth, Nonvital/*microbiology | Enzymology |
Metabolism | 14759706 | In vitro activation of the hemolysin in Prevotella nigrescens ATCC 33563 and Prevotella intermedia ATCC 25611. | Silva TA, Noronha FS, de Macedo Farias L, Carvalho MA | Res Microbiol | 10.1016/j.resmic.2003.09.010 | 2004 | Animals, Edetic Acid/pharmacology, Endopeptidase K/metabolism, Endopeptidases/metabolism, Enzyme Activation, Enzyme Inhibitors/pharmacology, Enzyme Stability, Hemolysin Proteins/*metabolism, *Hemolysis, Humans, Hydrogen-Ion Concentration, Kinetics, Leucine/*analogs & derivatives/pharmacology, Pepstatins/pharmacology, Phenylmethylsulfonyl Fluoride/pharmacology, Prevotella intermedia/growth & development/*metabolism, Prevotella nigrescens/growth & development/*metabolism, Rabbits, Temperature, Tosyllysine Chloromethyl Ketone/pharmacology, Trypsin/metabolism | Enzymology |
Pathogenicity | 15491347 | Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase. | Kim SJ, Ha MS, Choi EY, Choi JI, Choi IS | J Periodontal Res | 10.1111/j.1600-0765.2004.00757.x | 2004 | Animals, Blotting, Western, Cell Line, Enzyme Induction/drug effects, Gene Expression, Genistein/toxicity, Indoles/toxicity, Lipopolysaccharides/*pharmacology, Macrophages/drug effects/*enzymology/microbiology, Maleimides/toxicity, Mice, Microtubules/physiology, Nitric Oxide/*biosynthesis/toxicity, Nitric Oxide Synthase/*biosynthesis, Nitric Oxide Synthase Type II, Prevotella intermedia/*pathogenicity, Protein Kinase Inhibitors/toxicity, RNA, Messenger/analysis, Reverse Transcriptase Polymerase Chain Reaction | Enzymology |
Pathogenicity | 16490986 | The efficacy of povidone-iodine products against periodontopathic bacteria. | Nakagawa T, Hosaka Y, Ishihara K, Hiraishi T, Sato S, Ogawa T, Kamoi K | Dermatology | 10.1159/000089208 | 2006 | Aggregatibacter actinomycetemcomitans/drug effects, Anti-Infective Agents, Local/*pharmacology, Fusobacterium nucleatum/drug effects, Gram-Negative Bacteria/*drug effects, Humans, Mouth/*microbiology, Porphyromonas gingivalis/drug effects, Povidone-Iodine/*pharmacology, Prevotella intermedia/drug effects, Streptococcus anginosus/*drug effects | |
Pathogenicity | 16673792 | Antimicrobial effect in vitro of chlorhexidine and calcium hydroxide impregnated gutta-percha points. | Bozza FL, Molgatini SL, Perez SB, Tejerina DP, Perez Tito RI, Kaplan AE | Acta Odontol Latinoam | 2005 | Anti-Infective Agents, Local/*pharmacology, Calcium Hydroxide/*pharmacology, Candida albicans/drug effects, Chlorhexidine/*pharmacology, Colony Count, Microbial, Culture Media, Enterococcus faecalis/drug effects, Fusobacterium nucleatum/drug effects, *Gutta-Percha, Humans, Hydrogen-Ion Concentration, Materials Testing, Oxygen, Porphyromonas gingivalis/drug effects, Prevotella intermedia/drug effects, *Root Canal Filling Materials, Staphylococcus aureus/drug effects, Streptococcus mutans/drug effects, Temperature, Time Factors | Cultivation | |
Metabolism | 16806047 | Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia. | Sheng J, Nguyen PT, Baldeck JD, Olsson J, Marquis RE | Arch Oral Biol | 10.1016/j.archoralbio.2006.05.002 | 2006 | 2-Pyridinylmethylsulfinylbenzimidazoles/*pharmacology, Amino Acids/metabolism, Aminopeptidases/antagonists & inhibitors, Anaerobiosis/physiology, Anti-Infective Agents/*pharmacology, Enzyme Inhibitors/pharmacology, Fermentation, Fructose/metabolism, Fusobacterium nucleatum/*drug effects/metabolism, Glucose, Glutamic Acid/metabolism, Humans, Hydrogen-Ion Concentration, Lansoprazole, Lysine/metabolism, Mouth/*microbiology, Oxygen/metabolism, Prevotella intermedia/*drug effects/metabolism, Serine/metabolism | Pathogenicity |
16887668 | Susceptibility of Prevotella intermedia/Prevotella nigrescens (and Porphyromonas gingivalis) to propolis (bee glue) and other antimicrobial agents. | Santos FA, Bastos EM, Rodrigues PH, de Uzeda M, de Carvalho MA, Farias Lde M, Moreira ES | Anaerobe | 10.1006/anae.2002.0411 | 2002 | |||
Pathogenicity | 17064394 | The effects of tetracycline, minocycline, doxycycline and ofloxacin on Prevotella intermedia biofilm. | Takahashi N, Ishihara K, Kimizuka R, Okuda K, Kato T | Oral Microbiol Immunol | 10.1111/j.1399-302X.2006.00305.x | 2006 | Adenosine Triphosphate/metabolism, Anti-Bacterial Agents/*pharmacology, Biofilms/*drug effects, Colony Count, Microbial, Doxycycline/pharmacology, Luminescence, Microbial Sensitivity Tests, Minocycline/pharmacology, Ofloxacin/*pharmacology, Prevotella intermedia/*drug effects, Tetracycline/pharmacology, Tetracyclines/*pharmacology | Metabolism |
Metabolism | 17120973 | Effects of sonicated Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei extracts on interleukin-8 production by human dental pulp cells. | Thaweboon B, Thaweboon S, Choonharuangdej S, Suppakpatana P | Southeast Asian J Trop Med Public Health | 2006 | Adolescent, Adult, Bacterial Infections/*metabolism, Cell Survival, Cells, Cultured, Dental Pulp/metabolism/*microbiology, *Fusobacteria, Humans, Interleukin-8/*biosynthesis, *Lactobacillus casei, *Prevotella intermedia | Pathogenicity | |
Metabolism | 17229113 | Hemin nutritional stress inhibits bacterial invasion of radicular dentine by two endodontic anaerobes. | Love RM | Int Endod J | 10.1111/j.1365-2591.2006.01186.x | 2007 | Bacteria, Anaerobic/*metabolism, Culture Media, Dental Pulp Cavity/*microbiology, Dentin/*microbiology, Hemin/*metabolism, Humans, Peptostreptococcus/metabolism, Prevotella intermedia/metabolism | Cultivation |
Cultivation | 17584471 | Production of antagonistic substance by Eikenella corrodens isolated from the oral cavity of human beings with and without periodontal disease. | Apolonio AC, Carvalho MA, Ribas RN, Sousa-Gaia LG, Santos KV, Lana MA, Nicoli JR, Farias LM | J Appl Microbiol | 10.1111/j.1365-2672.2006.03211.x | 2007 | Acute Disease, *Antibiosis, Bacteriocins/*biosynthesis, Bacteriological Techniques, Chronic Disease, Culture Media, Eikenella corrodens/*metabolism/physiology, Gingiva/microbiology, Humans, Microbial Sensitivity Tests/methods, Mouth/*microbiology, Periodontitis/*microbiology | Pathogenicity |
Pathogenicity | 17727652 | Prevotella intermedia lipopolysaccharide stimulates release of tumor necrosis factor-alpha through mitogen-activated protein kinase signaling pathways in monocyte-derived macrophages. | Kim SJ, Choi EY, Kim EG, Shin SH, Lee JY, Choi JI, Choi IS | FEMS Immunol Med Microbiol | 10.1111/j.1574-695X.2007.00318.x | 2007 | Blotting, Western, Cell Line, Gene Expression, Humans, Lipopolysaccharides/*immunology, *MAP Kinase Signaling System, Macrophages/*immunology/*microbiology, Prevotella intermedia/*immunology/metabolism, RNA, Messenger/biosynthesis, Reverse Transcriptase Polymerase Chain Reaction, Tumor Necrosis Factor-alpha/genetics/*metabolism | Metabolism |
Pathogenicity | 17897190 | The influence of molecular oxygen exposure on the biology of Prevotella intermedia, with emphasis on its antibiotic susceptibility. | dos Santos SG, Diniz CG, da Silva VL, Souza NC, de Lima FL, Bomfim MR, de Carvalho MA, Farias LM | J Appl Microbiol | 10.1111/j.1365-2672.2007.03313.x | 2007 | Adaptation, Physiological, Anti-Bacterial Agents/*pharmacology, Bacterial Proteins/metabolism, Drug Resistance, Bacterial, Electrophoresis, Gel, Two-Dimensional/methods, Gene Expression Regulation, Bacterial, Genetic Variation, Humans, Microbial Sensitivity Tests, Oxidative Stress, Oxygen/*pharmacology, Polymerase Chain Reaction/methods, Prevotella intermedia/*drug effects/genetics/physiology | Enzymology |
Enzymology | 18400000 | Prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells. | Guan SM, Shu L, Fu SM, Liu B, Xu XL, Wu JZ | FEMS Microbiol Lett | 10.1111/j.1574-6968.2008.01140.x | 2008 | Adolescent, Anthracenes/pharmacology, Bacteroidaceae Infections/*microbiology, Butadienes/pharmacology, Cells, Cultured, Child, Culture Media, Conditioned, Electrophoresis, Polyacrylamide Gel, Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors, Humans, Imidazoles/pharmacology, Interleukin-1beta/pharmacology, JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors, Lipopolysaccharides/pharmacology, Matrix Metalloproteinase 9/*biosynthesis/metabolism, Nitriles/pharmacology, Periodontal Ligament/*enzymology/*microbiology, Porphyromonas gingivalis/pathogenicity, Prevotella intermedia/*pathogenicity, Protein Kinase Inhibitors/pharmacology, Pyrimidines/pharmacology, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors | Cultivation |
Pathogenicity | 18705525 | [Study of adherence of periodontal pathogens to collagen-treated hydroxyapatite]. | Sun CJ, Yang H, Lei CF, Xu Y, Wu YF | Hua Xi Kou Qiang Yi Xue Za Zhi | 2008 | *Aggregatibacter actinomycetemcomitans, Bacteria, Collagen, Durapatite, Fusobacterium nucleatum, Humans, Periodontitis, *Porphyromonas gingivalis, Prevotella intermedia | ||
Pathogenicity | 18814211 | Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria. | Park M, Bae J, Lee DS | Phytother Res | 10.1002/ptr.2473 | 2008 | Anti-Bacterial Agents/*pharmacology, Catechols/chemistry/*pharmacology, Chromatography, High Pressure Liquid, Fatty Alcohols/chemistry/*pharmacology, Ginger/chemistry, Humans, Microbial Sensitivity Tests, Periodontitis/microbiology, Plant Extracts/pharmacology, Porphyromonas endodontalis/*drug effects, Porphyromonas gingivalis/*drug effects, Prevotella intermedia/*drug effects, Spectrometry, Mass, Electrospray Ionization | |
Phylogeny | 19196771 | Prevotella falsenii sp. nov., a Prevotella intermedia-like organism isolated from monkey dental plaque. | Sakamoto M, Kumada H, Hamada N, Takahashi Y, Okamoto M, Bakir MA, Benno Y | Int J Syst Evol Microbiol | 10.1099/ijs.0.002626-0 | 2009 | Animals, Dental Plaque/*microbiology, Fatty Acids/analysis, Macaca fascicularis/*microbiology, Molecular Sequence Data, Phylogeny, Prevotella/chemistry/*classification/genetics, RNA, Ribosomal, 16S/genetics, Species Specificity | Genetics |
Pathogenicity | 19405834 | Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis. | Borch TS, Lobner M, Bendtzen K, Holmstrup P, Nielsen CH | J Periodontol | 10.1902/jop.2009.080513 | 2009 | Adolescent, Adult, Aggressive Periodontitis/*immunology/*microbiology, Case-Control Studies, Cells, Cultured, Cytokines/biosynthesis, Female, Fusobacterium nucleatum/immunology, Humans, Interferon-gamma/biosynthesis, Interleukin-2/biosynthesis/*immunology, Lymphocyte Activation/immunology, Male, Porphyromonas gingivalis/immunology, Prevotella intermedia/immunology, Smoking/adverse effects/metabolism, T-Lymphocytes, Helper-Inducer/*immunology/metabolism, Tetanus Toxoid/immunology, Young Adult | Metabolism |
19457170 | IL-17 is involved in bone resorption in mouse periapical lesions. | Oseko F, Yamamoto T, Akamatsu Y, Kanamura N, Iwakura Y, Imanishi J, Kita M | Microbiol Immunol | 10.1111/j.1348-0421.2009.00123.x | 2009 | Animals, Bacteroidaceae Infections/diagnostic imaging/*immunology/microbiology/physiopathology, *Bone Resorption, Female, Gene Expression, Interleukin-17/genetics/*immunology, Male, Mice, Mice, Inbred C57BL, Mice, Inbred ICR, Mice, Knockout, Periapical Diseases/diagnostic imaging/*immunology/microbiology/physiopathology, Porphyromonas gingivalis/immunology, Prevotella intermedia/immunology, Tomography, X-Ray Computed | ||
Pathogenicity | 19572892 | Prevotella intermedia ATCC 25611 targets host cell lamellipodia in epithelial cell adhesion and invasion. | Gursoy UK, Kononen E, Uitto VJ | Oral Microbiol Immunol | 10.1111/j.1399-302X.2009.00510.x | 2009 | Bacterial Adhesion, Cell Line, Cell Proliferation, Cell Survival, Epithelial Cells/*microbiology, Humans, Keratinocytes/microbiology, Prevotella intermedia/*physiology, Prevotella nigrescens/physiology, Pseudopodia/*microbiology, Skin/cytology, Species Specificity, Virulence | Phylogeny |
Phylogeny | 19654360 | Prevotella aurantiaca sp. nov., isolated from the human oral cavity. | Sakamoto M, Suzuki N, Okamoto M | Int J Syst Evol Microbiol | 10.1099/ijs.0.012831-0 | 2009 | DNA, Bacterial/genetics, DNA, Ribosomal/genetics, Fatty Acids/chemistry/metabolism, Humans, Molecular Sequence Data, Mouth/*microbiology, Periodontitis/microbiology, Phylogeny, Prevotella/*classification/genetics/*isolation & purification/metabolism, RNA, Ribosomal, 16S/genetics | Metabolism |
Pathogenicity | 19708869 | Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. | Guan SM, Shu L, Fu SM, Liu B, Xu XL, Wu JZ | FEMS Microbiol Lett | 10.1111/j.1574-6968.2009.01748.x | 2009 | Adolescent, Blotting, Western, Cells, Cultured, Child, Enzyme-Linked Immunosorbent Assay, Gene Expression Profiling, Humans, Matrix Metalloproteinase 1/*biosynthesis, Matrix Metalloproteinase 8/*biosynthesis, Periodontal Ligament/*chemistry/*microbiology, Prevotella intermedia/*physiology, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, *Up-Regulation | |
Enzymology | 19832801 | Characterization of L-cysteine desulfhydrase from Prevotella intermedia. | Yano T, Fukamachi H, Yamamoto M, Igarashi T | Oral Microbiol Immunol | 10.1111/j.1399-302X.2009.00546.x | 2009 | Amino Acid Substitution, Cloning, Molecular, Cystathionine gamma-Lyase/*chemistry/*genetics/metabolism, Hemolysis/*genetics/physiology, Hydrogen Sulfide/metabolism, Mutagenesis, Site-Directed, Prevotella intermedia/*enzymology, Recombinant Proteins | Metabolism |
Phylogeny | 19931406 | The identification of genes specific to Prevotella intermedia and Prevotella nigrescens using genomic subtractive hybridization. | Masakiyo Y, Yoshida A, Shintani Y, Takahashi Y, Ansai T, Takehara T | Anaerobe | 10.1016/j.anaerobe.2009.11.003 | 2009 | Acyltransferases/*genetics, DNA Transposable Elements/genetics, Genes, Bacterial, Nucleic Acid Hybridization/methods, Periodontitis/microbiology, Prevotella intermedia/*genetics/pathogenicity, Prevotella nigrescens/enzymology/*genetics, Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics, Species Specificity, Virulence/genetics | Enzymology |
Biotechnology | 20607056 | Leptin potentiates Prevotella intermedia lipopolysaccharide-induced production of TNF-alpha in monocyte-derived macrophages. | Kim SJ | J Periodontal Implant Sci | 10.5051/jpis.2010.40.3.119 | 2010 | ||
Metabolism | 21309717 | Effects of luteolin on the release of nitric oxide and interleukin-6 by macrophages stimulated with lipopolysaccharide from Prevotella intermedia. | Choi EY, Jin JY, Choi JI, Choi IS, Kim SJ | J Periodontol | 10.1902/jop.2011.100759 | 2011 | Animals, Anti-Inflammatory Agents/*pharmacology, Cell Line, Down-Regulation, Interleukin-6/antagonists & inhibitors/*biosynthesis, Lipopolysaccharides/*pharmacology, Luteolin/*pharmacology, MAP Kinase Signaling System, Macrophages/*drug effects/metabolism, Mice, NF-kappa B/antagonists & inhibitors/metabolism, Nitric Oxide/antagonists & inhibitors/*biosynthesis, Nitric Oxide Synthase Type II/metabolism, Phosphorylation, Prevotella intermedia/chemistry, Real-Time Polymerase Chain Reaction, STAT1 Transcription Factor/antagonists & inhibitors/metabolism | Pathogenicity |
Enzymology | 21658104 | Molecular basis of indole production catalyzed by tryptophanase in the genus Prevotella. | Sasaki-Imamura T, Yoshida Y, Suwabe K, Yoshimura F, Kato H | FEMS Microbiol Lett | 10.1111/j.1574-6968.2011.02329.x | 2011 | Animals, Bacterial Proteins/chemistry/genetics/*metabolism, Humans, Indoles/*metabolism, Kinetics, Molecular Sequence Data, Mouth/microbiology, Phylogeny, Prevotella/classification/*enzymology/genetics/isolation & purification, Tryptophanase/chemistry/genetics/*metabolism | Phylogeny |
Biotechnology | 21811692 | Curcumin suppresses the production of interleukin-6 in Prevotella intermedia lipopolysaccharide-activated RAW 264.7 cells. | Kim SJ | J Periodontal Implant Sci | 10.5051/jpis.2011.41.3.157 | 2011 | ||
Metabolism | 21864411 | Comparison of the virulence of exopolysaccharide-producing Prevotella intermedia to exopolysaccharide non-producing periodontopathic organisms. | Yamanaka T, Yamane K, Furukawa T, Matsumoto-Mashimo C, Sugimori C, Nambu T, Obata N, Walker CB, Leung KP, Fukushima H | BMC Infect Dis | 10.1186/1471-2334-11-228 | 2011 | Abscess/microbiology/pathology, Animals, Immune Evasion, Male, Mice, Mice, Inbred BALB C, Phagocytosis, Polysaccharides, Bacterial/*metabolism, Porphyromonas gingivalis/immunology/*metabolism/*pathogenicity, Prevotella intermedia/immunology/*metabolism/*pathogenicity, Virulence, Virulence Factors/*metabolism | |
Pathogenicity | 21972936 | Anti-inflammatory effects and the underlying mechanisms of action of daidzein in murine macrophages stimulated with Prevotella intermedia lipopolysaccharide. | Choi EY, Jin JY, Lee JY, Choi JI, Choi IS, Kim SJ | J Periodontal Res | 10.1111/j.1600-0765.2011.01422.x | 2011 | Animals, Anti-Inflammatory Agents/*pharmacology, Bacteriological Techniques, Cell Culture Techniques, Cell Line, Growth Inhibitors/*pharmacology, I-kappa B Kinase/drug effects, Inflammation Mediators/antagonists & inhibitors, Interleukin-6/antagonists & inhibitors, Isoflavones/*pharmacology, JNK Mitogen-Activated Protein Kinases/drug effects, Janus Kinase 2/drug effects, Lipopolysaccharides/*pharmacology, Macrophages/*drug effects, Mice, NF-kappa B/drug effects, NF-kappa B p50 Subunit/drug effects, Nitric Oxide Synthase Type II/drug effects, Phosphorylation, Phytoestrogens/*pharmacology, *Prevotella intermedia, STAT1 Transcription Factor/drug effects, Transcription Factor RelA/drug effects, p38 Mitogen-Activated Protein Kinases/drug effects | |
Pathogenicity | 22443519 | Human neutrophil defensins and their effect on epithelial cells. | Gursoy UK, Kononen E, Luukkonen N, Uitto VJ | J Periodontol | 10.1902/jop.2012.120017 | 2012 | Adult, Anti-Infective Agents/analysis/*pharmacology, Bacterial Adhesion/drug effects, Basement Membrane/pathology, Cell Adhesion/drug effects, Cell Death/drug effects, Cell Movement/drug effects, Cell Proliferation/drug effects, Cell Survival/drug effects, Chronic Periodontitis/pathology, Coated Materials, Biocompatible/chemistry, Dose-Response Relationship, Drug, Epithelial Attachment/drug effects/pathology, Epithelial Cells/drug effects/pathology, Female, Fibronectins/chemistry, Fusobacterium nucleatum/drug effects, Gingiva/*drug effects/pathology, Gingival Pocket/pathology, Humans, Keratinocytes/drug effects, Male, Middle Aged, Neutrophils/*physiology, Prevotella intermedia/drug effects, alpha-Defensins/analysis/*pharmacology | |
Cultivation | 22554902 | Contribution of hly homologs to the hemolytic activity of Prevotella intermedia. | Suzuki N, Fukamachi H, Arimoto T, Yamamoto M, Igarashi T | Anaerobe | 10.1016/j.anaerobe.2012.04.005 | 2012 | Animals, Bacterial Proteins/biosynthesis/*genetics, Culture Media, Erythrocytes/microbiology/pathology, Escherichia coli, Gene Expression, Gene Expression Regulation, Bacterial, Genes, Bacterial, Hemolysin Proteins/biosynthesis/*genetics, *Hemolysis, Iron/metabolism, Prevotella intermedia/*genetics/growth & development/metabolism, Recombinant Proteins/biosynthesis/genetics, Sheep | Metabolism |
Metabolism | 23266804 | Identification and functional analysis of the gene cluster for fructan utilization in Prevotella intermedia. | Fuse H, Fukamachi H, Inoue M, Igarashi T | Gene | 10.1016/j.gene.2012.12.023 | 2012 | Bacterial Proteins/genetics/metabolism, Chromosome Mapping, Culture Media, Fructans/*metabolism, Fructokinases/chemistry/genetics/metabolism, Fructose, Gene Expression, *Genes, Bacterial, Glycoside Hydrolases/genetics/metabolism, Hydrolysis, Inulin/metabolism, Monosaccharide Transport Proteins/genetics/metabolism, *Multigene Family, Prevotella intermedia/enzymology/*genetics/growth & development, Recombinant Proteins/genetics/metabolism, Sequence Analysis, DNA, Substrate Specificity | Cultivation |
Pathogenicity | 23441850 | Isorhamnetin inhibits Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages via anti-inflammatory heme oxygenase-1 induction and inhibition of nuclear factor-kappaB and signal transducer and activator of transcription 1 activation. | Jin JY, Choi EY, Park HR, Choi JI, Choi IS, Kim SJ | J Periodontal Res | 10.1111/jre.12054 | 2013 | Animals, Anti-Inflammatory Agents/antagonists & inhibitors/*metabolism, Antioxidants/*pharmacology, Cell Line, Down-Regulation, Enzyme Induction/drug effects, Enzyme Inhibitors/pharmacology, Heme Oxygenase-1/antagonists & inhibitors/biosynthesis/*drug effects, I-kappa B Proteins/drug effects, Interleukin-6/*antagonists & inhibitors, JNK Mitogen-Activated Protein Kinases/drug effects, Lipopolysaccharides/*antagonists & inhibitors, Macrophages/*drug effects/immunology, Membrane Proteins/antagonists & inhibitors/biosynthesis/*drug effects, Metalloporphyrins/pharmacology, Mice, NF-kappa B/*antagonists & inhibitors, NF-kappa B p50 Subunit/drug effects, Prevotella intermedia/*immunology, Protein Biosynthesis/drug effects, Protoporphyrins/pharmacology, Quercetin/*analogs & derivatives/pharmacology, STAT1 Transcription Factor/*antagonists & inhibitors, Transcription, Genetic/drug effects, Up-Regulation, p38 Mitogen-Activated Protein Kinases/drug effects | Biotechnology |
Biotechnology | 24040572 | Effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from Prevotella intermedia. | Cho YJ, Kim SJ | J Periodontal Implant Sci | 10.5051/jpis.2013.43.4.191 | 2013 | ||
Metabolism | 25601508 | Effect of caffeic acid phenethyl ester on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. | Choi EY, Choe SH, Hyeon JY, Choi JI, Choi IS, Kim SJ | J Periodontal Res | 10.1111/jre.12260 | 2015 | Animals, Caffeic Acids/*metabolism, Cytokines/*metabolism, Gene Expression Profiling, Immunologic Factors/*metabolism, Lipopolysaccharides/isolation & purification/*metabolism, Macrophages/*drug effects, Mice, NF-kappa B/metabolism, Nitric Oxide/*metabolism, Phenylethyl Alcohol/*analogs & derivatives/metabolism, Prevotella intermedia/chemistry, Real-Time Polymerase Chain Reaction | Pathogenicity |
Phylogeny | 25765460 | Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation. | Ruan Y, Shen L, Zou Y, Qi Z, Yin J, Jiang J, Guo L, He L, Chen Z, Tang Z, Qin S | BMC Genomics | 10.1186/s12864-015-1272-3 | 2015 | Adult, Animals, Bacterial Proteins/genetics, Bacteriocins/metabolism, *Comparative Genomic Hybridization, Contig Mapping, DNA/chemistry/isolation & purification, Dental Pulp Cavity/*microbiology, Drug Resistance, Bacterial/genetics, Erythrocytes/metabolism, *Genome, Bacterial, Hemolysis, Humans, Iron/metabolism, Male, Models, Theoretical, Multigene Family, Open Reading Frames/genetics, Phylogeny, Prevotella intermedia/classification/*genetics/pathogenicity, Sequence Analysis, DNA, Virulence Factors/genetics | Metabolism |
Pathogenicity | 26347298 | Identification of an antibacterial protein by functional screening of a human oral metagenomic library. | Arivaradarajan P, Warburton PJ, Paramasamy G, Nair SP, Allan E, Mullany P | FEMS Microbiol Lett | 10.1093/femsle/fnv142 | 2015 | Aldehyde Oxidoreductases/genetics, Amino Acid Sequence, Anti-Bacterial Agents/*chemistry/isolation & purification/pharmacology, Bacillus subtilis/drug effects, Bacteria/drug effects, Bacterial Proteins/*chemistry/isolation & purification/*pharmacology, Chromosomes, Artificial, Bacterial, Cloning, Molecular, Dental Plaque/*microbiology, Escherichia coli/genetics, Escherichia coli K12/drug effects, Genetic Vectors, Genomic Library, Humans, Lactobacillus casei/drug effects, *Metagenome, Molecular Sequence Data, Mutagenesis, Neisseria/*chemistry, Plasmids, Pseudomonas aeruginosa/drug effects, Saliva/*microbiology, Sequence Analysis, DNA, Staphylococcus aureus/drug effects, Staphylococcus epidermidis/drug effects | Enzymology |
Pathogenicity | 26406499 | Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors. | Barbosa GM, Colombo AV, Rodrigues PH, Simionato MR | PLoS One | 10.1371/journal.pone.0138687 | 2015 | Bacterial Adhesion, Biofilms/*growth & development, Biomass, Dysbiosis/microbiology, Humans, Periodontitis/microbiology, Porphyromonas gingivalis/classification/*physiology, Prevotella intermedia/classification/genetics/*physiology | Phylogeny |
Pathogenicity | 26655950 | Genistein suppresses Prevotella intermedia lipopolysaccharide-induced inflammatory response in macrophages and attenuates alveolar bone loss in ligature-induced periodontitis. | Choi EY, Bae SH, Ha MH, Choe SH, Hyeon JY, Choi JI, Choi IS, Kim SJ | Arch Oral Biol | 10.1016/j.archoralbio.2015.11.019 | 2015 | Alveolar Bone Loss/*drug therapy/genetics/metabolism, Animals, Disease Models, Animal, Gene Expression, Genistein/*pharmacology, Inflammation Mediators/*antagonists & inhibitors, Interleukin-6/antagonists & inhibitors/biosynthesis, Ligation, Lipopolysaccharides/*antagonists & inhibitors/isolation & purification/pharmacology, Macrophages/*drug effects/immunology, Male, Mice, Nitric Oxide/biosynthesis, Nitric Oxide Synthase Type II/antagonists & inhibitors/biosynthesis, Periodontitis/*drug therapy/genetics/immunology/metabolism, Prevotella intermedia/chemistry, RAW 264.7 Cells, RNA, Messenger/genetics, Random Allocation, Rats, Rats, Sprague-Dawley | Metabolism |
Metabolism | 27476978 | Nucleases from Prevotella intermedia can degrade neutrophil extracellular traps. | Doke M, Fukamachi H, Morisaki H, Arimoto T, Kataoka H, Kuwata H | Mol Oral Microbiol | 10.1111/omi.12171 | 2016 | Bacteria/enzymology/genetics/pathogenicity, Bacterial Proteins/genetics/metabolism, Culture Media/chemistry, DNA/*metabolism, Deoxyribonucleases/*metabolism, Extracellular Traps/*metabolism, Fusobacterium nucleatum/enzymology/genetics/pathogenicity, Genome, Bacterial, Humans, Neutrophils/*immunology/microbiology, Porphyromonas gingivalis/enzymology/genetics/pathogenicity, Prevotella intermedia/*enzymology/genetics/pathogenicity, RNA/metabolism | Enzymology |
Phylogeny | 27722787 | Bacterial invasion into radicular dentine-an in vitro study. | Stauffacher S, Lussi A, Nietzsche S, Neuhaus KW, Eick S | Clin Oral Investig | 10.1007/s00784-016-1960-7 | 2016 | Actinomyces/isolation & purification, Bacterial Load, Coculture Techniques, Dental Pulp Cavity/*microbiology, Dentin/*microbiology, Fusobacterium nucleatum/isolation & purification, Humans, In Vitro Techniques, Microscopy, Electron, Scanning, Porphyromonas gingivalis/isolation & purification, Prevotella intermedia/isolation & purification, Species Specificity, Streptococcus gordonii/isolation & purification, Streptococcus sanguis/isolation & purification | Enzymology |
Pathogenicity | 28578027 | Agomelatine, a MT1/MT2 melatonergic receptor agonist with serotonin 5-HT2C receptor antagonistic properties, suppresses Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages. | Hyeon JY, Choi EY, Choe SH, Park HR, Choi JI, Choi IS, Kim SJ | Arch Oral Biol | 10.1016/j.archoralbio.2017.05.015 | 2017 | Acetamides/*pharmacology, Animals, Cell Line, Enzyme-Linked Immunosorbent Assay, Immunoblotting, Inflammation Mediators/*antagonists & inhibitors, Interleukin-1beta/biosynthesis, Interleukin-6/biosynthesis, Lipopolysaccharides/pharmacology, Macrophages/*drug effects, Mice, NF-kappa B/biosynthesis, Nitric Oxide/biosynthesis, Nitric Oxide Synthase Type II/biosynthesis, Prevotella intermedia/*drug effects, RNA, Messenger/biosynthesis, Real-Time Polymerase Chain Reaction, STAT1 Transcription Factor/biosynthesis, STAT3 Transcription Factor/biosynthesis, Serotonin 5-HT2 Receptor Antagonists/*pharmacology, Suppressor of Cytokine Signaling 1 Protein/biosynthesis | Biotechnology |
Metabolism | 28934361 | Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia. | Johnston CD, Skeete CA, Fomenkov A, Roberts RJ, Rittling SR | PLoS One | 10.1371/journal.pone.0185234 | 2017 | Base Sequence, Biological Transport, Clustered Regularly Interspaced Short Palindromic Repeats/*genetics, DNA/*genetics/*metabolism, DNA Methylation, *Genomics, Humans, Prevotella intermedia/*genetics/*metabolism, Sequence Analysis, DNA | Genetics |
Pathogenicity | 30189320 | Quorum sensing molecules regulate epithelial cytokine response and biofilm-related virulence of three Prevotella species. | Fteita D, Kononen E, Gursoy M, Ma X, Sintim HO, Gursoy UK | Anaerobe | 10.1016/j.anaerobe.2018.09.001 | 2018 | Bacteroidaceae Infections/genetics/*immunology/microbiology, Biofilms, Epithelial Cells/*immunology/microbiology, Gingiva/*immunology/microbiology, Humans, Interleukin-1beta/genetics/*immunology, Interleukin-6/genetics/*immunology, Interleukin-8/genetics/*immunology, Keratinocytes/immunology/microbiology, Prevotella/classification/genetics/pathogenicity/*physiology, Prevotella intermedia/genetics/pathogenicity/physiology, Prevotella nigrescens/genetics/pathogenicity/physiology, *Quorum Sensing | Phylogeny |
30356383 | Antimicrobial Activity of Piper marginatum Jacq and Ilex guayusa Loes on Microorganisms Associated with Periodontal Disease. | Gamboa F, Munoz CC, Numpaque G, Sequeda-Castaneda LG, Gutierrez SJ, Tellez N | Int J Microbiol | 10.1155/2018/4147383 | 2018 | |||
32750671 | Influence of different ceramic materials and surface treatments on the adhesion of Prevotella intermedia. | Poole SF, Pitondo-Silva A, Oliveira-Silva M, Moris ICM, Gomes EA | J Mech Behav Biomed Mater | 10.1016/j.jmbbm.2020.104010 | 2020 | *Ceramics, *Computer-Aided Design, Dental Porcelain, Materials Testing, Prevotella intermedia, Surface Properties | ||
34158697 | In vitro antimicrobial effect of chloroaluminum phthalocyanine nanoemulsion on periodontal bacteria. | Rey LPL, Pinto SML, Muelhmann LA, Mendez LM, Sandoval LVH | J Indian Soc Periodontol | 10.4103/jisp.jisp_433_20 | 2021 | |||
Genetics | 35791444 | Genomic and phenotypic comparison of Prevotella intermedia strains possessing different virulence in vivo. | Kwack KH, Jang EY, Yang SB, Lee JH, Moon JH | Virulence | 10.1080/21505594.2022.2095718 | 2022 | Animals, Carbohydrates, *DNA Copy Number Variations, *Genomics, Heme, Iron, Mammals, Phylogeny, Prevotella intermedia/genetics, Virulence/genetics | Phylogeny |
Reference
@id | authors | catalogue | doi/url | title | journal | pubmed |
---|---|---|---|---|---|---|
8783 | Curators of the DSMZ | Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 20706) | https://www.dsmz.de/collection/catalogue/details/culture/DSM-20706 | |||
20215 | Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M. | 10.1099/ijsem.0.004332 | List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ | |||
20218 | Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P. | 10.1016/j.syapm.2013.11.002 | StrainInfo introduces electronic passports for microorganisms. | Syst Appl Microbiol. 37: 42-50 2014 | 24321274 | |
47910 | Curators of the CCUG | Culture Collection University of Gothenburg (CCUG) (CCUG 24041) | https://www.ccug.se/strain?id=24041 | |||
66792 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
67770 | Curators of the JCM | https://jcm.brc.riken.jp/en/ | ||||
67771 | Curators of the KCTC | https://kctc.kribb.re.kr/En/Kctc | ||||
68367 | Automatically annotated from API 20A | |||||
68380 | Automatically annotated from API rID32A | |||||
69479 | João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich. | https://microbeatlas.org/ | MicrobeAtlas 1.0 beta | |||
69480 | Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann | https://diaspora-project.de/progress.html#genomes | Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) | |||
69481 | Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch | 10.21203/rs.3.rs-2527258/v1 | Predictions based on the model GenomeNet Sporulation v. 1 | |||
81750 | Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J. | 10.60712/SI-ID38613.1 | StrainInfo: A central database for resolving microbial strain identifiers |