Strain identifier

BacDive ID: 10747

Type strain: Yes

Species: Nocardia cyriacigeorgica

Strain history: CIP <- 2002, DSMZ <- A.F. Yassin

NCBI tax ID(s): 1206728 (strain), 135487 (species)

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General

@ref: 11810

BacDive-ID: 10747

DSM-Number: 44484

keywords: genome sequence, 16S sequence, Bacteria, aerobe, mesophilic, Gram-positive

description: Nocardia cyriacigeorgica DSM 44484 is an aerobe, mesophilic, Gram-positive bacterium that was isolated from bronchial secretions.

NCBI tax id

NCBI tax idMatching level
1206728strain
135487species

strain history

@refhistory
11810<- A. F. Yassin; IMMIB D-1627
67770DSM 44484 <-- A. F. Yassin IMMIB D-1627.
118834CIP <- 2002, DSMZ <- A.F. Yassin

doi: 10.13145/bacdive10747.20250331.9.3

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: domain/bacteria
  • keyword: phylum/actinomycetota
  • domain: Bacteria
  • phylum: Actinomycetota
  • class: Actinomycetes
  • order: Mycobacteriales
  • family: Nocardiaceae
  • genus: Nocardia
  • species: Nocardia cyriacigeorgica
  • full scientific name: Nocardia cyriacigeorgica corrig. Yassin et al. 2001

  • synonyms

    • @ref: 20215
    • synonym: Nocardia cyriacigeorgici

@ref: 11810

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Actinomycetales

family: Nocardiaceae

genus: Nocardia

species: Nocardia cyriacigeorgica

full scientific name: Nocardia cyriacigeorgica Yassin et al. 2001

type strain: yes

Morphology

cell morphology

@refgram stainmotilityconfidence
118834positiveno
125438no91
125438positive92.899
125439positive99

colony morphology

  • @ref: 118834
  • hemolysis ability: 1

multimedia

@refmultimedia contentintellectual property rightscaption
11810https://www.dsmz.de/microorganisms/photos/DSM_44484-1.jpg© Leibniz-Institut DSMZ
11810https://www.dsmz.de/microorganisms/photos/DSM_44484.jpg© Leibniz-Institut DSMZMedium 65 28°C

Culture and growth conditions

culture medium

@refnamegrowthlinkcomposition
11810GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)yeshttps://mediadive.dsmz.de/medium/65Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water
39919MEDIUM 72- for trypto casein soja agaryesDistilled water make up to (1000.000 ml);Trypto casein soy agar (40.000 g)
118834CIP Medium 72yeshttps://catalogue-crbip.pasteur.fr/fiche_milieu.xhtml?crbip=72

culture temp

@refgrowthtypetemperature
11810positivegrowth28
39919positivegrowth30
58072positivegrowth30-37
67770positivegrowth28
118834positivegrowth25-45
118834nogrowth10

Physiology and metabolism

oxygen tolerance

@refoxygen toleranceconfidence
58072aerobe
118834obligate aerobe
125438aerobe90.397
125439obligate aerobe99.4

halophily

@refsaltgrowthtested relationconcentration
118834NaClpositivegrowth0-6 %
118834NaClnogrowth8 %
118834NaClnogrowth10 %

observation

  • @ref: 67770
  • observation: quinones: MK-8(H6, ω-cycl), 2,3-epoxy-MK-8(H6, ω-cycl)

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
11883416947citrate-carbon source
1188344853esculin+hydrolysis
118834606565hippurate-hydrolysis
11883417632nitrate+reduction
11883416301nitrite-reduction
11883417632nitrate-respiration
68371Potassium 5-ketogluconate-builds acid from
6837127613amygdalin-builds acid from
68371320061methyl alpha-D-glucopyranoside-builds acid from
6837115824D-fructose+builds acid from
6837117634D-glucose-builds acid from
6837112936D-galactose-builds acid from
68371Potassium 2-ketogluconate-builds acid from
6837124265gluconate-builds acid from
6837118403L-arabitol-builds acid from
6837118333D-arabitol-builds acid from
6837118287L-fucose-builds acid from
6837128847D-fucose-builds acid from
6837116443D-tagatose-builds acid from
6837162318D-lyxose-builds acid from
6837132528turanose-builds acid from
6837128066gentiobiose-builds acid from
6837117151xylitol-builds acid from
6837128017starch+builds acid from
6837116634raffinose-builds acid from
683716731melezitose-builds acid from
6837115443inulin-builds acid from
6837127082trehalose+builds acid from
6837117992sucrose-builds acid from
6837128053melibiose-builds acid from
6837117716lactose+builds acid from
6837117306maltose-builds acid from
6837117057cellobiose-builds acid from
6837117814salicin+builds acid from
683714853esculin-builds acid from
6837118305arbutin+builds acid from
6837159640N-acetylglucosamine-builds acid from
6837143943methyl alpha-D-mannoside-builds acid from
6837117924D-sorbitol-builds acid from
6837116899D-mannitol-builds acid from
6837117268myo-inositol-builds acid from
6837116813galactitol-builds acid from
6837162345L-rhamnose-builds acid from
6837117266L-sorbose-builds acid from
6837116024D-mannose-builds acid from
6837174863methyl beta-D-xylopyranoside-builds acid from
6837115963ribitol-builds acid from
6837165328L-xylose-builds acid from
6837165327D-xylose-builds acid from
6837130849L-arabinose-builds acid from
6837117108D-arabinose-builds acid from
6837117113erythritol-builds acid from
6837117754glycerol-builds acid from

antibiotic resistance

  • @ref: 118834
  • metabolite: 0129 (2,4-Diamino-6,7-di-iso-propylpteridine phosphate)
  • is antibiotic: yes
  • is sensitive: yes
  • is resistant: no

metabolite production

  • @ref: 118834
  • Chebi-ID: 35581
  • metabolite: indole
  • production: no

metabolite tests

@refChebi-IDmetabolitevoges-proskauer-testmethylred-test
11883415688acetoin-
11883417234glucose-

enzymes

@refvalueactivityec
68382alpha-fucosidase-3.2.1.51
68382alpha-mannosidase-3.2.1.24
68382N-acetyl-beta-glucosaminidase-3.2.1.52
68382beta-glucosidase+3.2.1.21
68382alpha-glucosidase+3.2.1.20
68382beta-glucuronidase-3.2.1.31
68382alpha-galactosidase-3.2.1.22
68382beta-galactosidase-3.2.1.23
68382naphthol-AS-BI-phosphohydrolase+
68382acid phosphatase+3.1.3.2
68382trypsin-3.4.21.4
68382cystine arylamidase-3.4.11.3
68382valine arylamidase+
68382leucine arylamidase+3.4.11.1
68382lipase (C 14)-
68382esterase lipase (C 8)+
68382alkaline phosphatase+3.1.3.1
68382esterase (C 4)+
118834oxidase-
118834beta-galactosidase-3.2.1.23
118834alcohol dehydrogenase-1.1.1.1
118834gelatinase-
118834amylase-
118834DNase-
118834caseinase-3.4.21.50
118834catalase+1.11.1.6
118834tween esterase-
118834gamma-glutamyltransferase-2.3.2.2
118834lecithinase-
118834lipase-
118834lysine decarboxylase-4.1.1.18
118834ornithine decarboxylase-4.1.1.17
118834phenylalanine ammonia-lyase-4.3.1.24
118834protease-
118834tryptophan deaminase-
118834urease-3.5.1.5
68382alpha-chymotrypsin-3.4.21.1

API zym

@refControlAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
118834-+++-++---++---++---

API 50CHac

@refGLYERYDARALARARIBDXYLLXYLADOMDXGALGLUFRUMNESBERHADULINOMANSORMDMMDGNAGAMYARBESCSALCELMALLACMELSACTREINUMLZRAFAMDGLYGXLTGENTURLYXTAGDFUCLFUCDARLLARLGNT2KG5KG
118834----+/-------+-----------+-+--+--+---++/-------------

API biotype100

@refGLUFRUGALTREMNESBEMELSACRAFMTEMALLACLTEMbGaMaGaCELGENMbGuESCRIBARAXYLPLERHAFUCMLZDARLLARLXLTDULTAGGLYINOMANMTLTURSORADOHBGLYXERYMDG3MDGSATMUCLTATDTATMTATDMLTLMLTCATETATETTECITGRTGAT2KG5KGTRYNAGGNTPACPATpOBEQATGTEmOBEBATPPATCMTTGEBETPCEABTHINLATCAPCYTHISSUCFUMGREGYTAVTETNTTNGLNITA3OBUAPTGTTPRODALALALASERMNTPROPTYR2KT
118834-+-------------------------------------------------------------------------+--+----++-+-+-+-----+-+

Isolation, sampling and environmental information

isolation

@refsample typegeographic locationcountryorigin.countrycontinent
11810bronchial secretionsGelsenkirchenGermanyDEUEurope
58072Human bronchial secretion,chronic bronchitisGelsenkirchenGermanyDEUEurope
67770Bronchial secretion with chronic bronchitis
118834Human, Bronchial secretionsGermanyDEUEurope

isolation source categories

Cat1Cat2
#Host Body-Site#Oral cavity and airways
#Host Body Product#Fluids

taxonmaps

  • @ref: 69479
  • File name: preview.99_369.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_10;96_243;97_280;98_312;99_369&stattab=map
  • Last taxonomy: Nocardia
  • 16S sequence: GQ376180
  • Sequence Identity:
  • Total samples: 780
  • soil counts: 340
  • aquatic counts: 144
  • animal counts: 241
  • plant counts: 55

Safety information

risk assessment

@refbiosafety levelbiosafety level comment
118102Risk group (German classification)
1188342Risk group (French classification)

Sequence information

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
20218Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, complete sequenceAF4300271494nuccore135487
20218Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequenceAY756550606nuccore135487
20218Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequenceDQ6599041404nuccore135487
20218Nocardia cyriacigeorgica 16S ribosomal RNA gene, partial sequenceGQ3761801441nuccore135487
20218Nocardia cyriacigeorgica strain DSM 44484 16S ribosomal RNA gene, partial sequenceJN041560462nuccore135487
67770Nocardia cyriacigeorgici 16S ribosomal RNA gene, complete sequenceAF2828891467nuccore135487

Genome sequences

@refdescriptionaccessionassembly leveldatabaseNCBI tax ID
66792Nocardia cyriacigeorgica DSM 44484GCA_005863225contigncbi135487
66792Nocardia cyriacigeorgica NBRC 1003751206728.4wgspatric1206728
66792Nocardia cyriacigeorgica strain DSM 44484135487.10wgspatric135487
66792Nocardia cyriacigeorgica NBRC 1003752551306157draftimg1206728
67770Nocardia cyriacigeorgica NBRC 100375GCA_000308555contigncbi1206728

GC content

@refGC-contentmethod
6777068-68.2high performance liquid chromatography (HPLC)
6777068.2genome sequence analysis

Genome-based predictions

predictions

@refmodeltraitdescriptionpredictionconfidencetraining_data
125439BacteriaNetoxygen_toleranceOxygenic conditions needed for growthobligate aerobe99.4
125439BacteriaNetgram_stainReaction to gram-stainingpositive99
125439BacteriaNetmotilityAbility to perform movementno86.6
125439BacteriaNetspore_formationAbility to form endo- or exosporesyes77.5
125438gram-positivegram-positivePositive reaction to Gram-stainingyes92.899no
125438anaerobicanaerobicAbility to grow under anoxygenic conditions (including facultative anaerobes)no98.246yes
125438spore-formingspore-formingAbility to form endo- or exosporesyes61.464no
125438aerobicaerobicAbility to grow under oxygenic conditions (including facultative aerobes)yes90.397yes
125438thermophilethermophilicAbility to grow at temperatures above or equal to 45°Cno97.494yes
125438motile2+flagellatedAbility to perform flagellated movementno91no

External links

@ref: 11810

culture collection no.: DSM 44484, CIP 107669, JCM 11763, NBRC 100375, CCUG 48295, IMMIB D-1627, IFM 10235

straininfo link

  • @ref: 80015
  • straininfo: 50649

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Phylogeny11491341Nocardia cyriacigeorgici sp. nov..Yassin AF, Rainey FA, Steiner UInt J Syst Evol Microbiol10.1099/00207713-51-4-14192001Base Composition, Bronchitis/microbiology, DNA, Bacterial/chemistry/genetics, Humans, Molecular Sequence Data, Nocardia/*classification/*genetics/isolation & purification/metabolism, Nocardia Infections/microbiology, Phylogeny, RNA, Bacterial/genetics, RNA, Ribosomal, 16S/genetics, Species Specificity, Terminology as TopicPathogenicity
Genetics31416867Genome Sequences of Three Nocardia cyriacigeorgica Strains and One Nocardia asteroides Strain.Vautrin F, Bergeron E, Dubost A, Abrouk D, Martin C, Cournoyer B, Louzier V, Winiarski T, Rodriguez-Nava V, Pujic PMicrobiol Resour Announc10.1128/MRA.00600-192019

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
11810Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 44484)https://www.dsmz.de/collection/catalogue/details/culture/DSM-44484
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
39919Curators of the CIPhttps://brclims.pasteur.fr/brcWeb/souche/detail/1/5130
58072Curators of the CCUGCulture Collection University of Gothenburg (CCUG) (CCUG 48295)https://www.ccug.se/strain?id=48295
66792Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmannhttps://diaspora-project.de/progress.html#genomesAutomatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information)
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68371Automatically annotated from API 50CH acid
68382Automatically annotated from API zym
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.https://microbeatlas.org/MicrobeAtlas 1.0 beta
80015Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.10.60712/SI-ID50649.1StrainInfo: A central database for resolving microbial strain identifiers
118834Curators of the CIPCollection of Institut Pasteur (CIP 107669)https://catalogue-crbip.pasteur.fr/fiche_catalogue.xhtml?crbip=CIP%20107669
125438Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann10.1101/2024.08.12.607695Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets
125439Philipp Münch, René Mreches, Martin Binder, Hüseyin Anil Gündüz, Xiao-Yin To, Alice McHardyhttps://github.com/GenomeNet/deepGdeepG: Deep Learning for Genome Sequence Data. R package version 0.3.1