Name: Staphylococcus aureus SA113
Creator: BacDive
License: http://creativecommons.org/licenses/by-nc/4.0/

Strain identifier

BacDive ID: 14451

Type strain:

Species: Staphylococcus aureus

Strain Designation: SA113

Culture col. no.: CCUG 41582, DSM 4910, ATCC 35556, NCTC 8325, CIP 107700

Strain history: CIP <- 2002, NCTC

NCBI tax ID(s): 93061 (strain), 1280 (species)

SI-ID 28647

NCTC8325, ATCC 35556, DSM 4910, CECT 4630, CCRC 12552, NCFB 1017, CCUG 41582, BCRC 12552, BCRC 14990, CCRC 14990, CIP 107700, LMG 21764

Other strains from Staphylococcus aureus

Section

Staphylococcus aureus SA113 is an aerobe, mesophilic, Gram-positive human pathogen of the family Staphylococcaceae.

Gram-positive
aerobe
human pathogen
mesophilic
Bacteria
genome sequence

Information on the name and the taxonomic classification. Name and taxonomic classification

	Last LPSN update	14-12-2023 (DD-MM-YYYY)
	Domain	"Bacteria"
	Phylum	*Bacillota*
	Class	*Bacilli*
	Order	*Caryophanales*
	Family	*Staphylococcaceae*
	Genus	*Staphylococcus*
	Species	**Staphylococcus aureus**
	Full Scientific Name (LPSN)	Staphylococcus aureus Rosenbach 1884 (Approved Lists 1980)

Synonym

Staphylococcus aureus subsp. anaerobius

Information on morphological and physiological properties Morphology

[Ref.: #116610]	Gram stain	positive
[Ref.: #69480]	Gram stain	positive Confidence in %100

[Ref.: #116610]	Cell shape	coccus-shaped

[Ref.: #116610]	Motility	no

Information on culture and growth conditions Culture and growth conditions

[Ref.: #1872]

Culture medium

NUTRIENT AGAR (DSMZ Medium 1)

[Ref.: #1872]

Culture medium growth

[Ref.: #1872]

Culture medium link

Medium recipe at MediaDive

[Ref.: #1872]

Culture medium composition

expand / minimize

[Ref.: #37375]

Culture medium

MEDIUM 72- for trypto casein soja agar

[Ref.: #37375]

Culture medium growth

[Ref.: #37375]

Culture medium composition

expand / minimize

[Ref.: #116610]

Culture medium

CIP Medium 72

[Ref.: #116610]

Culture medium growth

[Ref.: #116610]

Culture medium link

Medium recipe provided by DSMZ

	Kind of temperature		Temperature
[Ref.: #1872]		growth	37 °C
[Ref.: #37375]		growth	30 °C
[Ref.: #55133]		growth	37 °C
[Ref.: #116610]		growth	22-45 °C
[Ref.: #116610]	no	growth	10 °C

[Ref.: #1872]	Temperature range	mesophilic
[Ref.: #37375]	Temperature range	mesophilic
[Ref.: #55133]	Temperature range	mesophilic
[Ref.: #116610]	Temperature range	psychrophilic

Information on physiology and metabolism Physiology and metabolism

[Ref.: #55133]	Oxygen tolerance	aerobe
[Ref.: #116610]	Oxygen tolerance	facultative anaerobe

Note that the displayed test results represent raw data and therefore may deviate!

Antibiotic susceptibility testing

Test 1

Reference

[Ref.: #1872]
Mueller-Hinton Agar
37


yes
Inhibition zone diameter in mm
28
18
20
28
22-24
28
28
24
10
30
16
16
14
14
12
16
16
18
18
resistant0
10
12
12
6
14
14
14
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.
n.d.

Only first 15 entries are displayed. Click here to see all.

[Ref.: #69481]	Ability of spore formation	no Confidence in %99
[Ref.: #69480]	Ability of spore formation	no Confidence in %99.3

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #68375]	arabinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	arginine ChEBI	+	hydrolysis	* from API ID32STA
[Ref.: #68375]	cellobiose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	D-fructose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-glucose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannitol ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-mannose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	D-ribose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	esculin ChEBI	-	hydrolysis	* from API ID32STA
[Ref.: #116610]	hippurate ChEBI	+	hydrolysis
[Ref.: #68375]	lactose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	maltose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	N-acetylglucosamine ChEBI	+	fermentation	* from API ID32STA
[Ref.: #116610]	nitrate ChEBI	+	reduction
[Ref.: #68375]	nitrate ChEBI	+	reduction	* from API ID32STA
[Ref.: #116610]	nitrite ChEBI	+	reduction
[Ref.: #68375]	ornithine ChEBI	-	degradation	* from API ID32STA
[Ref.: #68375]	raffinose ChEBI	-	fermentation	* from API ID32STA
[Ref.: #68375]	sucrose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	trehalose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	turanose ChEBI	+	fermentation	* from API ID32STA
[Ref.: #68375]	urea ChEBI	-	hydrolysis	* from API ID32STA
	Only first 10 entries are displayed. Click here to see all.

	Antibiotica	Metabolite	Antibiotic sensitivity	Concentration
[Ref.: #68375]		novobiocin ChEBI	yes	1.8	µg	* from API ID32STA

	Metabolite	Production
[Ref.: #116610]	indole ChEBI	no
[Ref.: #116610]	polysaccharides	yes
[Ref.: #68375]	acetoin ChEBI	yes	* from API ID32STA

	Physiological tests	Metabolite	Voges-Proskauer-test
[Ref.: #116610]		acetoin ChEBI	+
[Ref.: #68375]		acetoin ChEBI	+	* from API ID32STA

	Enzyme	Enzyme activity	EC number
[Ref.: #68382]	acid phosphatase	+	3.1.3.2	* from API zym
[Ref.: #116610]	alcohol dehydrogenase	+	1.1.1.1
[Ref.: #68375]	alkaline phosphatase	+	3.1.3.1	* from API ID32STA, API zym
[Ref.: #68382]	alpha-chymotrypsin	-	3.4.21.1	* from API zym
[Ref.: #68382]	alpha-fucosidase	-	3.2.1.51	* from API zym
[Ref.: #68382]	alpha-galactosidase	-	3.2.1.22	* from API zym
[Ref.: #68382]	alpha-glucosidase	+	3.2.1.20	* from API zym
[Ref.: #68382]	alpha-mannosidase	-	3.2.1.24	* from API zym
[Ref.: #116610]	amylase	-
[Ref.: #68375]	arginine dihydrolase	+	3.5.3.6	* from API ID32STA
[Ref.: #116610]	beta-galactosidase	+	3.2.1.23
[Ref.: #68375]	beta-galactosidase	-	3.2.1.23	* from API ID32STA, API zym
[Ref.: #68375]	beta-glucosidase	-	3.2.1.21	* from API ID32STA, API zym
[Ref.: #68375]	beta-glucuronidase	-	3.2.1.31	* from API ID32STA, API zym
[Ref.: #116610]	caseinase	+	3.4.21.50
[Ref.: #116610]	catalase	+	1.11.1.6
[Ref.: #68382]	cystine arylamidase	-	3.4.11.3	* from API zym
[Ref.: #116610]	DNase	+
[Ref.: #68382]	esterase (C 4)	+		* from API zym
[Ref.: #68382]	esterase lipase (C 8)	+		* from API zym
[Ref.: #116610]	gamma-glutamyltransferase	-	2.3.2.2
[Ref.: #116610]	gelatinase	+/-
[Ref.: #68375]	L-arginine arylamidase	-		* from API ID32STA
[Ref.: #116610]	lecithinase	+
[Ref.: #68382]	leucine arylamidase	+	3.4.11.1	* from API zym
[Ref.: #116610]	lipase	+
[Ref.: #68382]	lipase (C 14)	-		* from API zym
[Ref.: #116610]	lysine decarboxylase	-	4.1.1.18
[Ref.: #68382]	N-acetyl-beta-glucosaminidase	-	3.2.1.52	* from API zym
[Ref.: #68382]	naphthol-AS-BI-phosphohydrolase	+		* from API zym
[Ref.: #116610]	ornithine decarboxylase	-	4.1.1.17
[Ref.: #68375]	ornithine decarboxylase	-	4.1.1.17	* from API ID32STA
[Ref.: #116610]	oxidase	-
[Ref.: #116610]	phenylalanine ammonia-lyase	-	4.3.1.24
[Ref.: #116610]	protease	+
[Ref.: #68375]	pyrrolidonyl arylamidase	-	3.4.19.3	* from API ID32STA
[Ref.: #68382]	trypsin	-	3.4.21.4	* from API zym
[Ref.: #116610]	tryptophan deaminase	-
[Ref.: #116610]	tween esterase	+
[Ref.: #116610]	urease	+	3.5.1.5
[Ref.: #68375]	urease	-	3.5.1.5	* from API ID32STA
[Ref.: #68382]	valine arylamidase	-		* from API zym
	Only first 10 entries are displayed. Click here to see all.

API® Biotype100:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	ControlQ	D-glucose as carbon sourceGLU	D-fructose as carbon sourceFRU	D-galactose as carbon sourceGAL	D-trehalose as carbon sourceTRE	D-mannose as carbon sourceMNE	L-sorbose as carbon sourceSBE	D-melibiose as carbon sourceMEL	sucrose as carbon sourceSAC	D-raffinose as carbon sourceRAF	maltotriose as carbon sourceMTE	maltose as carbon sourceMAL	lactose as carbon sourceLAC	lactulose as carbon sourceLTE	1-O-methyl-beta-galactopyranoside as carbon sourceMbGa	1-O-methyl-alpha-galactopyranoside as carbon sourceMaGa	D-cellobiose as carbon sourceCEL	gentiobiose as carbon sourceGEN	1-O-methyl-beta-D-glucopyranoside as carbon sourceMbGu	esculin as carbon sourceESC	D-ribose as carbon sourceRIB	L-arabinose as carbon sourceARA	D-xylose as carbon sourceXYL	palatinose as carbon sourcePLE	L-rhamnose as carbon sourceRHA	L-fucose as carbon sourceFUC	D-melezitose as carbon sourceMLZ	D-arabitol as carbon sourceDARL	L-arabitol as carbon sourceLARL	xylitol as carbon sourceXLT	dulcitol as carbon sourceDUL	D-tagatose as carbon sourceTAG	glycerol as carbon sourceGLY	myo-inositol as carbon sourceINO	D-mannitol as carbon sourceMAN	maltitol as carbon sourceMTL	D-turanose as carbon sourceTUR	D-sorbitol as carbon sourceSOR	adonitol as carbon sourceADO	hydroxyquinoline-beta-glucuronide as carbon sourceHBG	D-lyxose as carbon sourceLYX	i-erythritol as carbon sourceERY	1-O-methyl-alpha-D-glucoside as carbon sourceMDG	3-O-methyl-D-glucose as carbon source3MDG	D-saccharate as carbon sourceSAT	mucate as carbon sourceMUC	L-tartrate as carbon sourceLTAT	D-tartrate as carbon sourceDTAT	meso-tartrate as carbon sourceMTAT	D-malate as carbon sourceDMLT	L-malate as carbon sourceLMLT	cis-aconitate as carbon sourceCATE	trans-aconitate as carbon sourceTATE	tricarballylate as carbon sourceTTE	citrate as carbon sourceCIT	D-glucuronate as carbon sourceGRT	D-galacturonate as carbon sourceGAT	2-ketogluconate as carbon source2KG	5-ketogluconate as carbon source5KG	tryptophan as carbon sourceTRY	N-acetyl-D-glucosamine as carbon sourceNAG	D-gluconate as carbon sourceGNT	phenylacetate as carbon sourcePAC	protocatechuate as carbon sourcePAT	4-hydroxybenzoate as carbon sourcepOBE	quinate as carbon sourceQAT	gentisate as carbon sourceGTE	3-hydroxybenzoate as carbon sourcemOBE	benzoate as carbon sourceBAT	3-phenylpropionate as carbon sourcePPAT	m-coumarate as carbon sourceCMT	trigonelline as carbon sourceTGE	betaine as carbon sourceBET	putrescine as carbon sourcePCE	4-aminobutyrate as carbon sourceABT	histamine as carbon sourceHIN	DL-lactate as carbon sourceLAT	caprate as carbon sourceCAP	caprylate as carbon sourceCYT	L-histidine as carbon sourceHIS	succinate as carbon sourceSUC	fumarate as carbon sourceFUM	glutarate as carbon sourceGRE	DL-glycerate as carbon sourceGYT	5-aminovalerate as carbon sourceAVT	ethanolamine as carbon sourceETN	tryptamine as carbon sourceTTN	D-glucosamine as carbon sourceGLN	itaconate as carbon sourceITA	3-hydroxybutyrate as carbon source3OBU	L-aspartate as carbon sourceAPT	L-glutamate as carbon sourceGTT	L-proline as carbon sourcePRO	D-alanine as carbon sourceDALA	L-alanine as carbon sourceLALA	L-serine as carbon sourceSER	malonate as carbon sourceMNT	propionate as carbon sourcePROP	L-tyrosine as carbon sourceTYR	2-ketoglutarate as carbon source2KT
[Ref.: #116610]	2392	not determinedn.d.	+	+	+	+	+	-	-	+	-	+	+	+	+	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	-	+	-	-	-	-	+	-	-	-	-	-	-	-

API® ID32STA:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	Ornithine decarboxylaseODC	Esculin hydrolysisESC	Fermentation of D-glucoseGLU	Fermentation of D-fructoseFRU	Fermentation of D-mannoseMNE	Fermentation of maltoseMAL	Fermentation of lactoseLAC	Fermentation of trehaloseTRE	Fermentation of D-mannitolMAN	Fermentation of raffinoseRAF	Fermentation of D-riboseRIB	Fermentation of cellobioseCEL	Reduction of nitrateNIT	Acetoin production (Voges Proskauer test)VP	beta-Galactosidasebeta GAL	L-arginine arylamidaseArgA	Alkaline phosphatasePAL	Pyrrolidonyl arylamidasePyrA	Novobiocin resistanceNOVO	Fermentation of sucroseSAC	Fermentation of N-acetyl-glucosamineNAG	Fermentation of turanoseTUR	Fermentation of arabinoseARA	beta-Glucuronidasebeta GUR
[Ref.: #55133]	2170	-	+	-	-	+	+	+	+	+	+	+	-	-	-	+	+	-	-	+	-	-	+	+	+	-	-

API® zym:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Control	2-naphthyl phosphateAlkaline phosphatase	2-naphthyl butyrateEsterase (C 4)	2-naphtyl caprylateEsterase Lipase (C 8)	2-naphthyl myristateLipase (C 14)	L-leucyl-2-naphthylamideLeucine arylamidase	L-valyl-2-naphthylamideValine arylamidase	L-cystyl-2-naphthylamideCystine arylamidase	N-benzoyl-DL-arginine-2-naphthylamideTrypsin	N-glutaryl-phenylalanine-2-naphthylamidealpha- Chymotrypsin	2-naphthyl phosphateAcid phosphatase	Naphthol-AS-BI-phosphateNaphthol-AS-BI-phosphohydrolase	6-Br-2-naphthyl-alphaD-galactpyranosidealpha- Galactosidase	2-naphthyl-betaD-galactpyranosidebeta- Galactosidase	Naphthol-AS-BI-betaD-glucuronidebeta- Glucuronidase	2-naphthyl-alphaD-glucopyranosidealpha- Glucosidase	6-Br-2-naphthyl-betaD-glucopyranosidebeta- Glucosidase	1-naphthyl-N-acetyl-betaD-glucosaminideN-acetyl-beta- glucosaminidase	6-Br-2-naphthyl-alphaD-mannopyranosidealpha- Mannosidase	2-naphthyl-alphaL-fucopyranosidealpha- Fucosidase
[Ref.: #116610]	10580	-	+	+	+	-	+	-	-	-	-	+	+	-	-	-	+	-	-	-	-

	Pathway	Enzyme coverage	Annotated reactions
	Pathway annotation	Computationally determined by
[Ref.: #66794]	UDP-GlcNAc biosynthesis	100	3 of 3
[Ref.: #66794]	coenzyme A metabolism	100	4 of 4
[Ref.: #66794]	acetate fermentation	100	4 of 4
[Ref.: #66794]	ethanol fermentation	100	2 of 2
[Ref.: #66794]	vitamin K metabolism	100	5 of 5
[Ref.: #66794]	L-lactaldehyde degradation	100	3 of 3
[Ref.: #66794]	ribulose monophosphate pathway	100	2 of 2
[Ref.: #66794]	adipate degradation	100	2 of 2
[Ref.: #66794]	pentose phosphate pathway	100	11 of 11
[Ref.: #66794]	sulfopterin metabolism	100	4 of 4
[Ref.: #66794]	teichoic acid biosynthesis	100	1 of 1
[Ref.: #66794]	CDP-diacylglycerol biosynthesis	100	2 of 2
[Ref.: #66794]	butanoate fermentation	100	4 of 4
[Ref.: #66794]	folate polyglutamylation	100	1 of 1
[Ref.: #66794]	anapleurotic synthesis of oxalacetate	100	1 of 1
[Ref.: #66794]	acetoin degradation	100	3 of 3
[Ref.: #66794]	ceramide biosynthesis	100	1 of 1
[Ref.: #66794]	enterobactin biosynthesis	100	3 of 3
[Ref.: #66794]	biotin biosynthesis	100	4 of 4
[Ref.: #66794]	palmitate biosynthesis	95.45	21 of 22
[Ref.: #66794]	peptidoglycan biosynthesis	93.33	14 of 15
[Ref.: #66794]	vitamin B1 metabolism	92.31	12 of 13
[Ref.: #66794]	threonine metabolism	90	9 of 10
[Ref.: #66794]	valine metabolism	88.89	8 of 9
[Ref.: #66794]	chorismate metabolism	88.89	8 of 9
[Ref.: #66794]	gluconeogenesis	87.5	7 of 8
[Ref.: #66794]	C4 and CAM-carbon fixation	87.5	7 of 8
[Ref.: #66794]	ketogluconate metabolism	87.5	7 of 8
[Ref.: #66794]	heme metabolism	85.71	12 of 14
[Ref.: #66794]	tetrahydrofolate metabolism	85.71	12 of 14
[Ref.: #66794]	phenylalanine metabolism	84.62	11 of 13
[Ref.: #66794]	lipoate biosynthesis	80	4 of 5
[Ref.: #66794]	metabolism of amino sugars and derivatives	80	4 of 5
[Ref.: #66794]	pyrimidine metabolism	80	36 of 45
[Ref.: #66794]	glutamate and glutamine metabolism	78.57	22 of 28
[Ref.: #66794]	photosynthesis	78.57	11 of 14
[Ref.: #66794]	molybdenum cofactor biosynthesis	77.78	7 of 9
[Ref.: #66794]	leucine metabolism	76.92	10 of 13
[Ref.: #66794]	urea cycle	76.92	10 of 13
[Ref.: #66794]	purine metabolism	75.53	71 of 94
[Ref.: #66794]	degradation of sugar alcohols	75	12 of 16
[Ref.: #66794]	ppGpp biosynthesis	75	3 of 4
[Ref.: #66794]	isoleucine metabolism	75	6 of 8
[Ref.: #66794]	flavin biosynthesis	73.33	11 of 15
[Ref.: #66794]	citric acid cycle	71.43	10 of 14
[Ref.: #66794]	cardiolipin biosynthesis	71.43	5 of 7
[Ref.: #66794]	reductive acetyl coenzyme A pathway	71.43	5 of 7
[Ref.: #66794]	glycolysis	70.59	12 of 17
[Ref.: #66794]	Entner Doudoroff pathway	70	7 of 10
[Ref.: #66794]	methionine metabolism	69.23	18 of 26
[Ref.: #66794]	glycolate and glyoxylate degradation	66.67	4 of 6
[Ref.: #66794]	CO2 fixation in Crenarchaeota	66.67	6 of 9
[Ref.: #66794]	serine metabolism	66.67	6 of 9
[Ref.: #66794]	octane oxidation	66.67	2 of 3
[Ref.: #66794]	formaldehyde oxidation	66.67	2 of 3
[Ref.: #66794]	alanine metabolism	65.52	19 of 29
[Ref.: #66794]	histidine metabolism	65.52	19 of 29
[Ref.: #66794]	tryptophan metabolism	63.16	24 of 38
[Ref.: #66794]	arginine metabolism	62.5	15 of 24
[Ref.: #66794]	6-hydroxymethyl-dihydropterin diphosphate biosynthesis	62.5	5 of 8
[Ref.: #66794]	NAD metabolism	61.11	11 of 18
[Ref.: #66794]	glycogen metabolism	60	3 of 5
[Ref.: #66794]	starch degradation	60	6 of 10
[Ref.: #66794]	factor 420 biosynthesis	60	3 of 5
[Ref.: #66794]	methylglyoxal degradation	60	3 of 5
[Ref.: #66794]	oxidative phosphorylation	58.24	53 of 91
[Ref.: #66794]	non-pathway related	57.89	22 of 38
[Ref.: #66794]	propanol degradation	57.14	4 of 7
[Ref.: #66794]	aspartate and asparagine metabolism	55.56	5 of 9
[Ref.: #66794]	metabolism of disaccharids	54.55	6 of 11
[Ref.: #66794]	proline metabolism	54.55	6 of 11
[Ref.: #66794]	lysine metabolism	52.38	22 of 42
[Ref.: #66794]	glycine metabolism	50	5 of 10
[Ref.: #66794]	CMP-KDO biosynthesis	50	2 of 4
[Ref.: #66794]	pantothenate biosynthesis	50	3 of 6
[Ref.: #66794]	glutathione metabolism	50	7 of 14
[Ref.: #66794]	suberin monomers biosynthesis	50	1 of 2
[Ref.: #66794]	cysteine metabolism	50	9 of 18
[Ref.: #66794]	dolichol and dolichyl phosphate biosynthesis	50	1 of 2
[Ref.: #66794]	glycogen biosynthesis	50	2 of 4
[Ref.: #66794]	quinate degradation	50	1 of 2
[Ref.: #66794]	cis-vaccenate biosynthesis	50	1 of 2
[Ref.: #66794]	phenylmercury acetate degradation	50	1 of 2
[Ref.: #66794]	degradation of pentoses	46.43	13 of 28
[Ref.: #66794]	lipid metabolism	45.16	14 of 31
[Ref.: #66794]	d-mannose degradation	44.44	4 of 9
[Ref.: #66794]	mevalonate metabolism	42.86	3 of 7
[Ref.: #66794]	tyrosine metabolism	42.86	6 of 14
[Ref.: #66794]	degradation of aromatic, nitrogen containing compounds	41.67	5 of 12
[Ref.: #66794]	O-antigen biosynthesis	40	2 of 5
[Ref.: #66794]	myo-inositol biosynthesis	40	4 of 10
[Ref.: #66794]	propionate fermentation	40	4 of 10
[Ref.: #66794]	isoprenoid biosynthesis	38.46	10 of 26
[Ref.: #66794]	dTDPLrhamnose biosynthesis	37.5	3 of 8
[Ref.: #66794]	vitamin B6 metabolism	36.36	4 of 11
[Ref.: #66794]	cyanate degradation	33.33	1 of 3
[Ref.: #66794]	nitrate assimilation	33.33	3 of 9
[Ref.: #66794]	selenocysteine biosynthesis	33.33	2 of 6
[Ref.: #66794]	acetyl CoA biosynthesis	33.33	1 of 3
[Ref.: #66794]	lipid A biosynthesis	33.33	3 of 9
[Ref.: #66794]	(5R)-carbapenem carboxylate biosynthesis	33.33	1 of 3
[Ref.: #66794]	IAA biosynthesis	33.33	1 of 3
[Ref.: #66794]	degradation of hexoses	27.78	5 of 18
[Ref.: #66794]	d-xylose degradation	27.27	3 of 11
[Ref.: #66794]	polyamine pathway	26.09	6 of 23
[Ref.: #66794]	cyclohexanol degradation	25	1 of 4
[Ref.: #66794]	carnitine metabolism	25	2 of 8
[Ref.: #66794]	lactate fermentation	25	1 of 4
[Ref.: #66794]	toluene degradation	25	1 of 4
[Ref.: #66794]	sulfate reduction	23.08	3 of 13
[Ref.: #66794]	phenylpropanoid biosynthesis	23.08	3 of 13
[Ref.: #66794]	ascorbate metabolism	22.73	5 of 22
[Ref.: #66794]	carotenoid biosynthesis	22.73	5 of 22
[Ref.: #66794]	4-hydroxymandelate degradation	22.22	2 of 9
[Ref.: #66794]	arachidonic acid metabolism	22.22	4 of 18
[Ref.: #66794]	vitamin B12 metabolism	20.59	7 of 34
		Only first 10 entries are displayed. Click here to see all.

Information on possible application of the strain and its possible interaction with e.g. potential hosts Safety information

[Ref.: #1872]	Pathogenicity (human)	yes
[Ref.: #1872]	Pathogenicity (animal)	yes
[Ref.: #1872]	Biosafety level	2	Risk group (German classification) According to TRBA 466
[Ref.: #116610]	Biosafety level	2	Risk group (French classification)

Information on genomic background e.g. entries in nucleic sequence databass Sequence information

Genome sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence accession description	Seq. accession number	Assembly level	Sequence database	Associated NCBI tax ID
[Ref.: #66792]	Staphylococcus aureus subsp. aureus NCTC 8325	GCA_000013425	complete	GenBank	93061 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus NCTC 8325	GCA_900475245	complete	GenBank	93061 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus NCTC 8325	93061.5	complete	PATRIC	93061 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus NCTC 8325 strain NCTC8325	93061.132	complete	PATRIC	93061 tax ID	*
[Ref.: #66792]	Staphylococcus aureus subsp. aureus strain HG003	46170.125	wgs	PATRIC	1280 tax ID	*
[Ref.: #66792]	Staphylococcus aureus aureus NCTC 8325	637000279	complete	JGI IMG/M	93061 tax ID	*

Data predicted using genome information as a basis Genome-based predictions

	Trait	Prediction	Confidence in %	In training data
	Predictions from GenomeNet Sporulation v. 1 based on: Staphylococcus aureus subsp. aureus NCTC 8325 NCTC 8325 NCBI: GCA_000013425.1
[Ref.: #69481]	spore-forming	no	99	no

	Trait	Prediction	Confidence in %	In training data
	Predictions from Diaspora project based on: Staphylococcus aureus subsp. aureus NCTC 8325 NCTC 8325 NCBI: GCA_000013425.1
[Ref.: #69480]	motile	no	90.078	no
[Ref.: #69480]	flagellated	no	90.999	no
[Ref.: #69480]	gram-positive	yes	89.436	no
[Ref.: #69480]	anaerobic	no	99.48	no
[Ref.: #69480]	halophile	yes	93.501	no
[Ref.: #69480]	spore-forming	no	92.948	no
[Ref.: #69480]	glucose-util	yes	87.971	no
[Ref.: #69480]	aerobic	yes	89.483	yes
[Ref.: #69480]	thermophile	no	99.717	yes
[Ref.: #69480]	glucose-ferment	yes	85.53	yes

Availability in culture collections External links

[Ref.: #1872]

Culture collection no.

CCUG 41582, DSM 4910, ATCC 35556, NCTC 8325, CIP 107700

[Ref.: #83594]

SI-ID 28647

Literature:

Only first 10 entries are displayed. Click here to see all.

	Title	Authors	Journal	DOI	Year
Pathogenicity	Clemastine Inhibits the Biofilm and Hemolytic of Staphylococcus aureus through the GdpP Protein.	Shang Y, Guo J, Zhao Y, Chen J, Meng Q, Qu D, Zheng J, Yu Z, Wu Y, Deng Q	Microbiol Spectr	10.1128/spectrum.00541-21	2022	*
Metabolism	Heterologous production of active form of beta-lytic protease by Bacillus subtilis and improvement of staphylolytic activity by protein engineering.	Hioki T, Yamashita D, Tohata M, Endo K, Kawahara A, Okuda M	Microb Cell Fact	10.1186/s12934-021-01724-x	2021	*
Pathogenicity	Effect of biofilm on the survival of Staphylococcus aureus isolated from raw milk in high temperature and drying environment.	Shen J, Wang H, Zhu C, Zhang M, Shang F, Xue T	Food Res Int	10.1016/j.foodres.2021.110672	2021	*
Pathogenicity	Nutraceutical Potential of Leaf Hydro-Ethanolic Extract of the Edible Halophyte Crithmum maritimum L.	Souid A, Della Croce CM, Frassinetti S, Gabriele M, Pozzo L, Ciardi M, Abdelly C, Hamed KB, Magne C, Longo V	Molecules	10.3390/molecules26175380	2021	*
Metabolism	DNA glycosylases for 8-oxoguanine repair in Staphylococcus aureus.	Endutkin AV, Panferova EP, Barmatov AE, Zharkov DO	DNA Repair (Amst)	10.1016/j.dnarep.2021.103160	2021	*
Pathogenicity	Acidic amino acids as counterions of ciprofloxacin: Effect on growth and pigment production in Staphylococcus aureus NCTC 8325 and Pseudomonas aeruginosa PAO1.	Warraich AA, Mohammed AUR, Gibson H, Hussain M, Rahman AS	PLoS One	10.1371/journal.pone.0250705	2021	*
Metabolism	Protein A of Staphylococcus aureus strain NCTC8325 interacted with heparin.	Shi H, Tang J, An C, Yang L, Zhou X	Arch Microbiol	10.1007/s00203-021-02255-0	2021	*
Pathogenicity	[Inhibitory effect of Ningmitai Capsules on the proliferation and biofilm formation of Staphylococcus sp. and Escherichia coli].	Chen X, Zheng L, Chen DK	Zhonghua Nan Ke Xue		2020	*
Pathogenicity	Antibacterial Property of Composites of Reduced Graphene Oxide with Nano-Silver and Zinc Oxide Nanoparticles Synthesized Using a Microwave-Assisted Approach.	Hsueh YH, Hsieh CT, Chiu ST, Tsai PH, Liu CY, Ke WJ	Int J Mol Sci	10.3390/ijms20215394	2019	*
Pathogenicity	Development of Mangifera indica leaf extract incorporated carbopol hydrogel and its antibacterial efficacy against Staphylococcus aureus.	Chirayath RB, A AV, Jayakumar R, Biswas R, Vijayachandran LS	Colloids Surf B Biointerfaces	10.1016/j.colsurfb.2019.03.034	2019	*
Pathogenicity	Essential Oil, Extracts, and Sesquiterpenes Obtained From the Heartwood of Pilgerodendron uviferum Act as Potential Inhibitors of the Staphylococcus aureus NorA Multidrug Efflux Pump.	Espinoza J, Urzua A, Sanhueza L, Walter M, Fincheira P, Munoz P, Mendoza L, Wilkens M	Front Microbiol	10.3389/fmicb.2019.00337	2019	*
Pathogenicity	A Novel Method to Eliminate Preservatives in Eye Drops.	Stanton D, Batich C, Schultz G, Gibson D, Guidi C, Yang Q, Bechtle A, Eiferman R	J Ocul Pharmacol Ther	10.1089/jop.2018.0042	2018	*
Pathogenicity	Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion.	Tian T, Wang C, Wu M, Zhang X, Zang J	Biochemistry	10.1021/acs.biochem.8b00028	2018	*
Phylogeny	Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers.	Ajayi C, Aberg E, Askarian F, Sollid JUE, Johannessen M, Hanssen AM	BMC Microbiol	10.1186/s12866-018-1179-7	2018	*
Genetics	AureoWiki The repository of the Staphylococcus aureus research and annotation community.	Fuchs S, Mehlan H, Bernhardt J, Hennig A, Michalik S, Surmann K, Pane-Farre J, Giese A, Weiss S, Backert L, Herbig A, Nieselt K, Hecker M, Volker U, Mader U	Int J Med Microbiol	10.1016/j.ijmm.2017.11.011	2017	*
Metabolism	Staphylococcus aureus from atopic dermatitis skin alters cytokine production triggered by monocyte-derived Langerhans cell.	Iwamoto K, Moriwaki M, Niitsu Y, Saino M, Takahagi S, Hisatsune J, Sugai M, Hide M	J Dermatol Sci	10.1016/j.jdermsci.2017.08.001	2017	*
Metabolism	Impact of cell wall peptidoglycan O-acetylation on the pathogenesis of Staphylococcus aureus in septic arthritis.	Baranwal G, Mohammad M, Jarneborn A, Reddy BR, Golla A, Chakravarty S, Biswas L, Gotz F, Shankarappa S, Jin T, Biswas R	Int J Med Microbiol	10.1016/j.ijmm.2017.08.002	2017	*
Metabolism	Identification of Set11 from Staphylococcus aureus Mu50 strain as a ortholog of SSL7 via bioinformatic analysis and determination of its possible targets from human serum using CNBr-pull down assays.	Li Y, Chen X, Jia N, Zhang X, Zang J	Biotechnol Lett	10.1007/s10529-017-2374-6	2017	*
Metabolism	AI-2 quorum sensing negatively regulates rbf expression and biofilm formation in Staphylococcus aureus.	Ma R, Qiu S, Jiang Q, Sun H, Xue T, Cai G, Sun B	Int J Med Microbiol	10.1016/j.ijmm.2017.03.003	2017	*
Metabolism	The Role of Bacillithiol in Gram-Positive Firmicutes.	Chandrangsu P, Loi VV, Antelmann H, Helmann JD	Antioxid Redox Signal	10.1089/ars.2017.7057	2017	*
Metabolism	A Novel Repressor of the ica Locus Discovered in Clinically Isolated Super-Biofilm-Elaborating Staphylococcus aureus.	Yu L, Hisatsune J, Hayashi I, Tatsukawa N, Sato'o Y, Mizumachi E, Kato F, Hirakawa H, Pier GB, Sugai M	mBio	10.1128/mBio.02282-16	2017	*
Metabolism	Serine-Aspartate Repeat Protein D Increases Staphylococcus aureus Virulence and Survival in Blood.	Askarian F, Uchiyama S, Valderrama JA, Ajayi C, Sollid JUE, van Sorge NM, Nizet V, van Strijp JAG, Johannessen M	Infect Immun	10.1128/IAI.00559-16	2016	*
Metabolism	Penicillin binding protein 3 of Staphylococcus aureus NCTC 8325-4 binds and activates human plasminogen.	Kylvaja R, Ojalehto T, Kainulainen V, Virkola R, Westerlund-Wikstrom B	BMC Res Notes	10.1186/s13104-016-2190-4	2016	*
Pathogenicity	Structure of the host-recognition device of Staphylococcus aureus phage varphi11.	Koc C, Xia G, Kuhner P, Spinelli S, Roussel A, Cambillau C, Stehle T	Sci Rep	10.1038/srep27581	2016	*
Transcriptome	Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.	Mader U, Nicolas P, Depke M, Pane-Farre J, Debarbouille M, van der Kooi-Pol MM, Guerin C, Derozier S, Hiron A, Jarmer H, Leduc A, Michalik S, Reilman E, Schaffer M, Schmidt F, Bessieres P, Noirot P, Hecker M, Msadek T, Volker U, van Dijl JM	PLoS Genet	10.1371/journal.pgen.1005962	2016	*
Pathogenicity	The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells.	Askarian F, Ajayi C, Hanssen AM, van Sorge NM, Pettersen I, Diep DB, Sollid JU, Johannessen M	Sci Rep	10.1038/srep22134	2016	*
Genetics	Genome-wide Annotation, Identification, and Global Transcriptomic Analysis of Regulatory or Small RNA Gene Expression in Staphylococcus aureus.	Carroll RK, Weiss A, Broach WH, Wiemels RE, Mogen AB, Rice KC, Shaw LN	mBio	10.1128/mBio.01990-15	2016	*
Pathogenicity	Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis.	Lerche CJ, Christophersen LJ, Trostrup H, Thomsen K, Jensen PO, Hougen HP, Bundgaard H, Hoiby N, Moser C	Eur J Clin Microbiol Infect Dis	10.1007/s10096-015-2488-5	2015	*
Pathogenicity	The nuSaalpha Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.	Nguyen MT, Kraft B, Yu W, Demircioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Gotz F	PLoS Pathog	10.1371/journal.ppat.1004984	2015	*
Metabolism	The Staphylococcus aureus protein-coding gene gdpS modulates sarS expression via mRNA-mRNA interaction.	Chen C, Zhang X, Shang F, Sun H, Sun B, Xue T	Infect Immun	10.1128/IAI.00159-15	2015	*
Metabolism	Elucidating the crucial role of poly N-acetylglucosamine from Staphylococcus aureus in cellular adhesion and pathogenesis.	Lin MH, Shu JC, Lin LP, Chong KY, Cheng YW, Du JF, Liu ST	PLoS One	10.1371/journal.pone.0124216	2015	*
Genetics	SRD: a Staphylococcus regulatory RNA database.	Sassi M, Augagneur Y, Mauro T, Ivain L, Chabelskaya S, Hallier M, Sallou O, Felden B	RNA	10.1261/rna.049346.114	2015	*
Pathogenicity	A putative cro-like repressor contributes to arylomycin resistance in Staphylococcus aureus.	Craney A, Romesberg FE	Antimicrob Agents Chemother	10.1128/AAC.04597-14	2015	*
Pathogenicity	Antibacterial activity of Mulinum spinosum extracts against slime-producing Staphylococcus aureus and methicillin-resistant Staphylococcus aureus isolated from nasal carriers.	Daniela E, Alejandra C, Pedro R, Claudia M, Lucia A, Carlos T, Analia L, Sara S	ScientificWorldJournal	10.1155/2014/342143	2014	*
Pathogenicity	New antibacterial xanthone from the marine sponge-derived Micrococcus sp. EG45.	Eltamany EE, Abdelmohsen UR, Ibrahim AK, Hassanean HA, Hentschel U, Ahmed SA	Bioorg Med Chem Lett	10.1016/j.bmcl.2014.09.040	2014	*
Metabolism	Pfs promotes autolysis-dependent release of eDNA and biofilm formation in Staphylococcus aureus.	Bao Y, Zhang X, Jiang Q, Xue T, Sun B	Med Microbiol Immunol	10.1007/s00430-014-0357-y	2014	*
Genetics	Draft Genome Sequence of Staphylococcus aureus subsp. aureus Strain HG003, an NCTC8325 Derivative.	Sassi M, Felden B, Augagneur Y	Genome Announc	10.1128/genomeA.00855-14	2014	*
Pathogenicity	NOD2 stimulation by Staphylococcus aureus-derived peptidoglycan is boosted by Toll-like receptor 2 costimulation with lipoproteins in dendritic cells.	Schaffler H, Demircioglu DD, Kuhner D, Menz S, Bender A, Autenrieth IB, Bodammer P, Lamprecht G, Gotz F, Frick JS	Infect Immun	10.1128/IAI.02043-14	2014	*
Genetics	Generation of a vancomycin-intermediate Staphylococcus aureus (VISA) strain by two amino acid exchanges in VraS.	Berscheid A, Francois P, Strittmatter A, Gottschalk G, Schrenzel J, Sass P, Bierbaum G	J Antimicrob Chemother	10.1093/jac/dku297	2014	*
Metabolism	Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains.	Kneuper H, Cao ZP, Twomey KB, Zoltner M, Jager F, Cargill JS, Chalmers J, van der Kooi-Pol MM, van Dijl JM, Ryan RP, Hunter WN, Palmer T	Mol Microbiol	10.1111/mmi.12707	2014	*
Metabolism	Metabolic and transcriptional activities of Staphylococcus aureus challenged with high-doses of daptomycin.	Lechner S, Prax M, Lange B, Huber C, Eisenreich W, Herbig A, Nieselt K, Bertram R	Int J Med Microbiol	10.1016/j.ijmm.2014.05.008	2014	*
Pathogenicity	Leonurus cardiaca L. herb--a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis.	Micota B, Sadowska B, Podsedek A, Redzynia M, Rozalska B	Acta Biochim Pol	2013_651	2014	*
Metabolism	Staphylococcus aureus glucose-induced biofilm accessory proteins, GbaAB, influence biofilm formation in a PIA-dependent manner.	You Y, Xue T, Cao L, Zhao L, Sun H, Sun B	Int J Med Microbiol	10.1016/j.ijmm.2014.04.003	2014	*
Pathogenicity	Antimicrobial activity of Hibiscus sabdariffa aqueous extracts against Escherichia coli O157:H7 and Staphylococcus aureus in a microbiological medium and milk of various fat concentrations.	Higginbotham KL, Burris KP, Zivanovic S, Davidson PM, Stewart CN Jr	J Food Prot	10.4315/0362-028X.JFP-13-313	2014	*
Enzymology	Expression, purification, crystallization and preliminary X-ray diffraction studies of phosphoglycerate mutase from Staphylococcus aureus NCTC8325.	Roychowdhury A, Kundu A, Gujar A, Bose M, Das AK	Acta Crystallogr F Struct Biol Commun	10.1107/S2053230X13031476	2013	*
Pathogenicity	Modulation of cell wall synthesis and susceptibility to vancomycin by the two-component system AirSR in Staphylococcus aureus NCTC8325.	Sun H, Yang Y, Xue T, Sun B	BMC Microbiol	10.1186/1471-2180-13-286	2013	*
Enzymology	Porcine models of non-bacterial thrombotic endocarditis (NBTE) and infective endocarditis (IE) caused by Staphylococcus aureus: a preliminary study.	Christiansen JG, Jensen HE, Johansen LK, Kochl J, Koch J, Aalbaek B, Nielsen OL, Leifsson PS	J Heart Valve Dis		2013	*
Transcriptome	RNA-Seq reveals differential gene expression in Staphylococcus aureus with single-nucleotide resolution.	Osmundson J, Dewell S, Darst SA	PLoS One	10.1371/journal.pone.0076572	2013	*
Metabolism	Role of Rot in bacterial autolysis regulation of Staphylococcus aureus NCTC8325.	Chu X, Xia R, He N, Fang Y	Res Microbiol	10.1016/j.resmic.2013.06.001	2013	*
Pathogenicity	Design, synthesis and antistaphylococcal activity of marine pyrrole alkaloid derivatives.	Rane RA, Sahu NU, Shah CP, Shah NK	J Enzyme Inhib Med Chem	10.3109/14756366.2013.793183	2013	*
Pathogenicity	Distribution and infection-related functions of bacillithiol in Staphylococcus aureus.	Pother DC, Gierok P, Harms M, Mostertz J, Hochgrafe F, Antelmann H, Hamilton CJ, Borovok I, Lalk M, Aharonowitz Y, Hecker M	Int J Med Microbiol	10.1016/j.ijmm.2013.01.003	2013	*
Pathogenicity	Antimicrobial activity of nanodispersed thymol in tryptic soy broth.	Shah B, Davidson PM, Zhong Q	J Food Prot	10.4315/0362-028X.JFP-12-354	2013	*
Pathogenicity	Interplay between population dynamics and drug tolerance of Staphylococcus aureus persister cells.	Lechner S, Patra P, Klumpp S, Bertram R	J Mol Microbiol Biotechnol	10.1159/000346073	2013	*
Metabolism	Trapping and proteomic identification of cellular substrates of the ClpP protease in Staphylococcus aureus.	Feng J, Michalik S, Varming AN, Andersen JH, Albrecht D, Jelsbak L, Krieger S, Ohlsen K, Hecker M, Gerth U, Ingmer H, Frees D	J Proteome Res	10.1021/pr300394r	2013	*
Pathogenicity	Electrochemically deposited gentamicin-loaded calcium phosphate coatings for bone tissue integration.	Altomare L, Visai L, Bloise N, Arciola CR, Ulivi L, Candiani G, Cigada A, Chiesa R, De Nardo L	Int J Artif Organs	10.5301/ijao.5000162	2012	*
Metabolism	LuxS/AI-2 system is involved in antibiotic susceptibility and autolysis in Staphylococcus aureus NCTC 8325.	Xue T, Zhao L, Sun B	Int J Antimicrob Agents	10.1016/j.ijantimicag.2012.08.016	2012	*
Metabolism	Staphylococcus aureus persisters tolerant to bactericidal antibiotics.	Lechner S, Lewis K, Bertram R	J Mol Microbiol Biotechnol	10.1159/000342449	2012	*
Metabolism	WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation.	Mauthe M, Yu W, Krut O, Kronke M, Gotz F, Robenek H, Proikas-Cezanne T	Int J Cell Biol	10.1155/2012/179207	2012	*
Pathogenicity	Involvement of iron in biofilm formation by Staphylococcus aureus.	Lin MH, Shu JC, Huang HY, Cheng YC	PLoS One	10.1371/journal.pone.0034388	2012	*
Metabolism	Type I signal peptidase and protein secretion in Staphylococcus aureus.	Schallenberger MA, Niessen S, Shao C, Fowler BJ, Romesberg FE	J Bacteriol	10.1128/JB.00064-12	2012	*
Genetics	Revisiting the genomes of the Staphylococcus aureus strains NCTC 8325 and RN4220.	Berscheid A, Sass P, Weber-Lassalle K, Cheung AL, Bierbaum G	Int J Med Microbiol	10.1016/j.ijmm.2012.01.002	2012	*
Metabolism	New insights into Staphylococcus aureus stress tolerance and virulence regulation from an analysis of the role of the ClpP protease in the strains Newman, COL, and SA564.	Frees D, Andersen JH, Hemmingsen L, Koskenniemi K, Baek KT, Muhammed MK, Gudeta DD, Nyman TA, Sukura A, Varmanen P, Savijoki K	J Proteome Res	10.1021/pr200956s	2011	*
Metabolism	Rot and Agr system modulate fibrinogen-binding ability mainly by regulating clfB expression in Staphylococcus aureus NCTC8325.	Xue T, You Y, Shang F, Sun B	Med Microbiol Immunol	10.1007/s00430-011-0208-z	2011	*
Metabolism	Multiple peptide resistance factor (MprF)-mediated Resistance of Staphylococcus aureus against antimicrobial peptides coincides with a modulated peptide interaction with artificial membranes comprising lysyl-phosphatidylglycerol.	Andra J, Goldmann T, Ernst CM, Peschel A, Gutsmann T	J Biol Chem	10.1074/jbc.M111.226886	2011	*
Genetics	Whole-genome sequencing of Staphylococcus aureus strain RN4220, a key laboratory strain used in virulence research, identifies mutations that affect not only virulence factors but also the fitness of the strain.	Nair D, Memmi G, Hernandez D, Bard J, Beaume M, Gill S, Francois P, Cheung AL	J Bacteriol	10.1128/JB.00027-11	2011	*
Pathogenicity	Impact of ciprofloxacin exposure on Staphylococcus aureus genomic alterations linked with emergence of rifampin resistance.	Didier JP, Villet R, Huggler E, Lew DP, Hooper DC, Kelley WL, Vaudaux P	Antimicrob Agents Chemother	10.1128/AAC.01407-10	2011	*
Proteome	Structural evidence of alpha-aminoacylated lipoproteins of Staphylococcus aureus.	Asanuma M, Kurokawa K, Ichikawa R, Ryu KH, Chae JH, Dohmae N, Lee BL, Nakayama H	FEBS J	10.1111/j.1742-4658.2010.07990.x	2011	*
Pathogenicity	Synergistic effects of sodium hypochlorite and ultraviolet radiation in reducing the levels of selected foodborne pathogenic bacteria.	Ha JH, Ha SD	Foodborne Pathog Dis	10.1089/fpd.2010.0761	2011	*
Enzymology	Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.	Ettefagh KA, Burns JT, Junio HA, Kaatz GW, Cech NB	Planta Med	10.1055/s-0030-1250606	2010	*
Metabolism	The heme sensing response regulator HssR in Staphylococcus aureus but not the homologous RR23 in Listeria monocytogenes modulates susceptibility to the antimicrobial peptide plectasin.	Thomsen LE, Gottlieb CT, Gottschalk S, Wodskou TT, Kristensen HH, Gram L, Ingmer H	BMC Microbiol	10.1186/1471-2180-10-307	2010	*
Pathogenicity	Generation of ramoplanin-resistant Staphylococcus aureus.	Schmidt JW, Greenough A, Burns M, Luteran AE, McCafferty DG	FEMS Microbiol Lett	10.1111/j.1574-6968.2010.02051.x	2010	*
Genetics	Staphylococcus aureus SH1000 and 8325-4: comparative genome sequences of key laboratory strains in staphylococcal research.	O'Neill AJ	Lett Appl Microbiol	10.1111/j.1472-765X.2010.02885.x	2010	*
Metabolism	Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence.	Zhao L, Xue T, Shang F, Sun H, Sun B	Infect Immun	10.1128/IAI.00131-10	2010	*
Pathogenicity	Immune evasion cluster-positive bacteriophages are highly prevalent among human Staphylococcus aureus strains, but they are not essential in the first stages of nasal colonization.	Verkaik NJ, Benard M, Boelens HA, de Vogel CP, Nouwen JL, Verbrugh HA, Melles DC, van Belkum A, van Wamel WJ	Clin Microbiol Infect	10.1111/j.1469-0691.2010.03227.x	2011	*
Pathogenicity	Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates.	Herbert S, Ziebandt AK, Ohlsen K, Schafer T, Hecker M, Albrecht D, Novick R, Gotz F	Infect Immun	10.1128/IAI.00088-10	2010	*
Pathogenicity	Synergistic effects of ethanol and UV radiation to reduce levels of selected foodborne pathogenic bacteria.	Ha JH, Ha SD	J Food Prot	10.4315/0362-028x-73.3.556	2010	*
Metabolism	Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR.	Opperman TJ, Williams JD, Houseweart C, Panchal RG, Bavari S, Peet NP, Moir DT, Bowlin TL	Bioorg Med Chem	10.1016/j.bmc.2010.02.005	2010	*
Genetics	Development of pooled suppression subtractive hybridization to analyze the pangenome of Staphylococcus aureus.	Gerrish RS, Gill AL, Fowler VG, Gill SR	J Microbiol Methods	10.1016/j.mimet.2010.01.022	2010	*
Enzymology	Cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC 8325.	Bhattacharyya S, Dutta D, Ghosh AK, Das AK	Acta Crystallogr Sect F Struct Biol Cryst Commun	10.1107/S1744309109037580	2009	*
Pathogenicity	Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus.	Jelsbak L, Hemmingsen L, Donat S, Ohlsen K, Boye K, Westh H, Ingmer H, Frees D	Int J Med Microbiol	10.1016/j.ijmm.2009.07.003	2009	*
Pathogenicity	Caenorhabditis elegans as a host model for community-associated methicillin-resistant Staphylococcus aureus.	Wu K, Conly J, McClure JA, Elsayed S, Louie T, Zhang K	Clin Microbiol Infect	10.1111/j.1469-0691.2009.02765.x	2009	*
Pathogenicity	Lipoproteins in Staphylococcus aureus mediate inflammation by TLR2 and iron-dependent growth in vivo.	Schmaler M, Jann NJ, Ferracin F, Landolt LZ, Biswas L, Gotz F, Landmann R	J Immunol	10.4049/jimmunol.0804292	2009	*
Pathogenicity	The inability of a bacteriophage to infect Staphylococcus aureus does not prevent it from specifically delivering a photosensitizer to the bacterium enabling its lethal photosensitization.	Hope CK, Packer S, Wilson M, Nair SP	J Antimicrob Chemother	10.1093/jac/dkp157	2009	*
Pathogenicity	The Staphylococcus aureus GGDEF domain-containing protein, GdpS, influences protein A gene expression in a cyclic diguanylic acid-independent manner.	Shang F, Xue T, Sun H, Xing L, Zhang S, Yang Z, Zhang L, Sun B	Infect Immun	10.1128/IAI.01405-08	2009	*
Pathogenicity	Identification by genomic and genetic analysis of two new genes playing a key role in intermediate glycopeptide resistance in Staphylococcus aureus.	Renzoni A, Kelley WL, Barras C, Monod A, Huggler E, Francois P, Schrenzel J, Studer R, Vaudaux P, Lew DP	Antimicrob Agents Chemother	10.1128/AAC.01287-08	2008	*
Metabolism	The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.	Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Gotz F, Peschel A	BMC Microbiol	10.1186/1471-2180-8-85	2008	*
Metabolism	Sequence diversity in the A domain of Staphylococcus aureus fibronectin-binding protein A.	Loughman A, Sweeney T, Keane FM, Pietrocola G, Speziale P, Foster TJ	BMC Microbiol	10.1186/1471-2180-8-74	2008	*
Metabolism	Staphylococcus aureus CcpA affects biofilm formation.	Seidl K, Goerke C, Wolz C, Mack D, Berger-Bachi B, Bischoff M	Infect Immun	10.1128/IAI.00035-08	2008	*
Metabolism	Regulatory organization of the staphylococcal sae locus.	Adhikari RP, Novick RP	Microbiology (Reading)	10.1099/mic.0.2007/012245-0	2008	*
Metabolism	Late-stage polyribitol phosphate wall teichoic acid biosynthesis in Staphylococcus aureus.	Meredith TC, Swoboda JG, Walker S	J Bacteriol	10.1128/JB.01880-07	2008	*
Phylogeny	Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands.	Baba T, Bae T, Schneewind O, Takeuchi F, Hiramatsu K	J Bacteriol	10.1128/JB.01000-07	2007	*
Pathogenicity	Inhibition of staphylococcal biofilm formation by nitrite.	Schlag S, Nerz C, Birkenstock TA, Altenberend F, Gotz F	J Bacteriol	10.1128/JB.00598-07	2007	*
Pathogenicity	A Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity.	Fedtke I, Mader D, Kohler T, Moll H, Nicholson G, Biswas R, Henseler K, Gotz F, Zahringer U, Peschel A	Mol Microbiol	10.1111/j.1365-2958.2007.05854.x	2007	*
Metabolism	SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS.	Oscarsson J, Kanth A, Tegmark-Wisell K, Arvidson S	J Bacteriol	10.1128/JB.00866-06	2006	*
Transcriptome	Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390.	Cassat J, Dunman PM, Murphy E, Projan SJ, Beenken KE, Palm KJ, Yang SJ, Rice KC, Bayles KW, Smeltzer MS	Microbiology (Reading)	10.1099/mic.0.29033-0	2006	*
Proteome	In vivo survival of teicoplanin-resistant Staphylococcus aureus and fitness cost of teicoplanin resistance.	McCallum N, Karauzum H, Getzmann R, Bischoff M, Majcherczyk P, Berger-Bachi B, Landmann R	Antimicrob Agents Chemother	10.1128/AAC.00073-06	2006	*
Metabolism	Lack of wall teichoic acids in Staphylococcus aureus leads to reduced interactions with endothelial cells and to attenuated virulence in a rabbit model of endocarditis.	Weidenmaier C, Peschel A, Xiong YQ, Kristian SA, Dietz K, Yeaman MR, Bayer AS	J Infect Dis	10.1086/429692	2005	*
Genetics	Staphylococcus aureus deficient in lipidation of prelipoproteins is attenuated in growth and immune activation.	Stoll H, Dengjel J, Nerz C, Gotz F	Infect Immun	10.1128/IAI.73.4.2411-2423.2005	2005	*
Metabolism	Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model.	Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM	Infect Immun	10.1128/IAI.73.2.872-877.2005	2005	*
Phylogeny	Comparative genomics of Staphylococcus aureus musculoskeletal isolates.	Cassat JE, Dunman PM, McAleese F, Murphy E, Projan SJ, Smeltzer MS	J Bacteriol	10.1128/JB.187.2.576-592.2005	2005	*
Pathogenicity	Regulation of the expression of cell wall stress stimulon member gene msrA1 in methicillin-susceptible or -resistant Staphylococcus aureus.	Pechous R, Ledala N, Wilkinson BJ, Jayaswal RK	Antimicrob Agents Chemother	10.1128/AAC.48.8.3057-3063.2004	2004	*
Enzymology	Global gene expression in Staphylococcus aureus biofilms.	Beenken KE, Dunman PM, McAleese F, Macapagal D, Murphy E, Projan SJ, Blevins JS, Smeltzer MS	J Bacteriol	10.1128/JB.186.14.4665-4684.2004	2004	*
Genetics	TcaR, a putative MarR-like regulator of sarS expression.	McCallum N, Bischoff M, Maki H, Wada A, Berger-Bachi B	J Bacteriol	10.1128/JB.186.10.2966-2972.2004	2004	*
Pathogenicity	The ability of biofilm formation does not influence virulence of Staphylococcus aureus and host response in a mouse tissue cage infection model.	Kristian SA, Golda T, Ferracin F, Cramton SE, Neumeister B, Peschel A, Gotz F, Landmann R	Microb Pathog	10.1016/j.micpath.2003.12.004	2004	*
Pathogenicity	Mutations are involved in emergence of aminoglycoside-induced small colony variants of Staphylococcus aureus.	Schaaff F, Bierbaum G, Baumert N, Bartmann P, Sahl HG	Int J Med Microbiol	10.1078/1438-4221-00282	2003	*
Genetics	Control of glucose- and NaCl-induced biofilm formation by rbf in Staphylococcus aureus.	Lim Y, Jana M, Luong TT, Lee CY	J Bacteriol	10.1128/JB.186.3.722-729.2004	2004	*
Phylogeny	[Changes in Staphylococcus aureus susceptibility to bactericidal action of teicoplanin in the presence of different prophages in the bacterial genome].	Mlynarczyk G, Mlynarczyk A, Zabicka D, Luczak M	Med Dosw Mikrobiol		2003	*
Metabolism	Correlation of acetate catabolism and growth yield in Staphylococcus aureus: implications for host-pathogen interactions.	Somerville GA, Said-Salim B, Wickman JM, Raffel SJ, Kreiswirth BN, Musser JM	Infect Immun	10.1128/IAI.71.8.4724-4732.2003	2003	*
Pathogenicity	Alanylation of teichoic acids protects Staphylococcus aureus against Toll-like receptor 2-dependent host defense in a mouse tissue cage infection model.	Kristian SA, Lauth X, Nizet V, Goetz F, Neumeister B, Peschel A, Landmann R	J Infect Dis	10.1086/376533	2003	*
Enzymology	Characteristic expression of three genes, msr(A), mph(C) and erm(Y), that confer resistance to macrolide antibiotics on Staphylococcus aureus.	Matsuoka M, Inoue M, Endo Y, Nakajima Y	FEMS Microbiol Lett	10.1016/S0378-1097(03)00134-4	2003	*
Genetics	Type 1 capsule genes of Staphylococcus aureus are carried in a staphylococcal cassette chromosome genetic element.	Luong TT, Ouyang S, Bush K, Lee CY	J Bacteriol	10.1128/JB.184.13.3623-3629.2002	2002	*
Enzymology	In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.	Yamakawa T, Mitsuyama J, Hayashi K	J Antimicrob Chemother	10.1093/jac/49.3.455	2002	*
Phylogeny	Identification of Staphylococcus aureus based on PCR amplification of species specific genomic 826 bp sequence derived from a common 44-kb Sma I restriction fragment.	Stepan J, Pantucek R, Ruzickova V, Rosypal S, Hajek V, Doskar J	Mol Cell Probes	10.1006/mcpr.2001.0368	2001	*
Metabolism	Influence of a functional sigB operon on the global regulators sar and agr in Staphylococcus aureus.	Bischoff M, Entenza JM, Giachino P	J Bacteriol	10.1128/JB.183.17.5171-5179.2001	2001	*
Enzymology	Proteolytic cleavage of staphylococcal exoproteins analyzed by two-dimensional gel electrophoresis.	Kawano Y, Kawagishi M, Nakano M, Mase K, Yamashino T, Hasegawa T, Ohta M	Microbiol Immunol	10.1111/j.1348-0421.2001.tb02620.x	2001	*
Metabolism	Sigma(B) activity depends on RsbU in Staphylococcus aureus.	Giachino P, Engelmann S, Bischoff M	J Bacteriol	10.1128/JB.183.6.1843-1852.2001	2001	*
Phylogeny	Rapid isolation and identification of staphylococcal exoproteins by reverse phase capillary high performance liquid chromatography-electrospray ionization mass spectrometry.	Kawano Y, Ito Y, Yamakawa Y, Yamashino T, Horii T, Hasegawa T, Ohta M	FEMS Microbiol Lett	10.1111/j.1574-6968.2000.tb09214.x	2000	*
Phylogeny	[Characteristics of penicillinase plasmids from Staphylococcus aureus strains].	Mlynarczyk A, Mlynarczyk G, Jeljaszewicz J	Med Dosw Mikrobiol		1999	*
Metabolism	Induction of fibronectin-binding proteins and increased adhesion of quinolone-resistant Staphylococcus aureus by subinhibitory levels of ciprofloxacin.	Bisognano C, Vaudaux P, Rohner P, Lew DP, Hooper DC	Antimicrob Agents Chemother	10.1128/AAC.44.6.1428-1437.2000	2000	*
Pathogenicity	Identification of an immunodominant ABC transporter in methicillin-resistant Staphylococcus aureus infections.	Burnie JP, Matthews RC, Carter T, Beaulieu E, Donohoe M, Chapman C, Williamson P, Hodgetts SJ	Infect Immun	10.1128/IAI.68.6.3200-3209.2000	2000	*
Pathogenicity	[Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus].	Matsuoka M	Yakugaku Zasshi	10.1248/yakushi1947.120.4_374	2000	*
Metabolism	The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil).	Cox SD, Mann CM, Markham JL, Bell HC, Gustafson JE, Warmington JR, Wyllie SG	J Appl Microbiol	10.1046/j.1365-2672.2000.00943.x	2000	*
Phylogeny	Regulation of sigmaB-dependent transcription of sigB and asp23 in two different Staphylococcus aureus strains.	Gertz S, Engelmann S, Schmid R, Ohlsen K, Hacker J, Hecker M	Mol Gen Genet	10.1007/s004380051001	1999	*
Phylogeny	Validation of binary typing for Staphylococcus aureus strains.	van Leeuwen W, Verbrugh H, van der Velden J, van Leeuwen N, Heck M, van Belkum A	J Clin Microbiol	10.1128/JCM.37.3.664-674.1999	1999	*
Pathogenicity	Antibacterial activity of gatifloxacin (AM-1155, CG5501, BMS-206584), a newly developed fluoroquinolone, against sequentially acquired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus.	Fukuda H, Hori S, Hiramatsu K	Antimicrob Agents Chemother	10.1128/AAC.42.8.1917	1998	*
Metabolism	Teichoic acid content in different lineages of Staphylococcus aureus NCTC8325.	Jenni R, Berger-Bachi B	Arch Microbiol	10.1007/s002030050630	1998	*
Pathogenicity	N-terminal sequence polymorphism in the coagulase gene of Staphylococcus aureus and its potential use as an epidemiological marker.	el-Adhami W, Stewart P	J Hosp Infect	10.1016/s0195-6701(98)90079-2	1998	*
Phenotype	Introduction of the mec element (methicillin resistance) into Staphylococcus aureus alters in vitro functional activities of fibrinogen and fibronectin adhesins.	Vaudaux PE, Monzillo V, Francois P, Lew DP, Foster TJ, Berger-Bachi B	Antimicrob Agents Chemother	10.1128/AAC.42.3.564	1998	*
Genetics	The Staphylococcus aureus scdA gene: a novel locus that affects cell division and morphogenesis.	Brunskill EW, de Jonge BLM, Bayles KW	Microbiology (Reading)	10.1099/00221287-143-9-2877	1997	*
Genetics	The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes.	Sau S, Bhasin N, Wann ER, Lee JC, Foster TJ, Lee CY	Microbiology (Reading)	10.1099/00221287-143-7-2395	1997	*
Pathogenicity	Increased expression of fibronectin-binding proteins by fluoroquinolone-resistant Staphylococcus aureus exposed to subinhibitory levels of ciprofloxacin.	Bisognano C, Vaudaux PE, Lew DP, Ng EY, Hooper DC	Antimicrob Agents Chemother	10.1128/AAC.41.5.906	1997	*
Phylogeny	[Lysogenic conversion as a factor influencing tolerance to vancomycin in Staphylococcus aureus].	Mlynarczyk G, Mlynarczyk A, Zabicka D, Jeljaszewicz J	Med Dosw Mikrobiol		1997	*
Phylogeny	Construction of a chromosome map for the phage group II Staphylococcus aureus Ps55.	Bannantine JP, Pattee PA	J Bacteriol	10.1128/jb.178.23.6842-6848.1996	1996	*
Phylogeny	Localization of prophages of serological group B and F on restriction fragments defined in the restriction map of Staphylococcus aureus NCTC 8325.	Borecka P, Rosypal S, Pantucek R, Doskar J	FEMS Microbiol Lett	10.1111/j.1574-6968.1996.tb08481.x	1996	*
Metabolism	Hydrophilicity of quinolones is not an exclusive factor for decreased activity in efflux-mediated resistant mutants of Staphylococcus aureus.	Takenouchi T, Tabata F, Iwata Y, Hanzawa H, Sugawara M, Ohya S	Antimicrob Agents Chemother	10.1128/AAC.40.8.1835	1996	*
Metabolism	Proline is biosynthesized from arginine in Staphylococcus aureus.	Townsend DE, Kaenjak A, Jayaswal RK, Wilkinson BJ	Microbiology (Reading)	10.1099/13500872-142-6-1491	1996	*
Enzymology	Sequence, expression in Escherichia coli, and analysis of the gene encoding a novel intracellular protease (PfpI) from the hyperthermophilic archaeon Pyrococcus furiosus.	Halio SB, Blumentals II, Short SA, Merrill BM, Kelly RM	J Bacteriol	10.1128/jb.178.9.2605-2612.1996	1996	*
Enzymology	Identification and molecular characterization of a putative regulatory locus that affects autolysis in Staphylococcus aureus.	Brunskill EW, Bayles KW	J Bacteriol	10.1128/jb.178.3.611-618.1996	1996	*
Enzymology	Characterization and overexpression of the gene encoding Staphylococcus aureus DNA polymerase III.	Pacitti DF, Barnes MH, Li DH, Brown NC	Gene	10.1016/0378-1119(95)00377-i	1995	*
Pathogenicity	A mechanism of resistance to partial macrolide and streptogramin B antibiotics in Staphylococcus aureus clinically isolated in Hungary.	Matsuoka M, Endou K, Saitoh S, Katoh M, Nakajima Y	Biol Pharm Bull	10.1248/bpb.18.1482	1995	*
Enzymology	Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome.	Ng EY, Trucksis M, Hooper DC	Antimicrob Agents Chemother	10.1128/AAC.38.6.1345	1994	*
Enzymology	The femC locus of Staphylococcus aureus required for methicillin resistance includes the glutamine synthetase operon.	Gustafson J, Strassle A, Hachler H, Kayser FH, Berger-Bachi B	J Bacteriol	10.1128/jb.176.5.1460-1467.1994	1994	*
Transcriptome	Sequence analysis of the region downstream from a peptidoglycan hydrolase-encoding gene from Staphylococcus aureus NCTC8325.	Borchardt SA, Babwah AV, Jayaswal RK	Gene	10.1016/0378-1119(93)90016-v	1993	*
Phylogeny	Molecular cloning and mapping of 16S-23S rRNA gene complexes of Staphylococcus aureus.	Wada A, Ohta H, Kulthanan K, Hiramatsu K	J Bacteriol	10.1128/jb.175.22.7483-7487.1993	1993	*
Pathogenicity	Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus.	Endou K, Matsuoka M, Taniguchi H, Nakajima Y	J Antibiot (Tokyo)	10.7164/antibiotics.46.478	1993	*
Pathogenicity	Phage-related conversion of enterotoxin A, staphylokinase and beta-toxin in Staphylococcus aureus.	Zabicka D, Mlynarczyk A, Windyga B, Mlynarczyk G	Acta Microbiol Pol		1993	*
Enzymology	Analysis of a peptidoglycan hydrolase gene from Staphylococcus aureus NCTC 8325.	Wang X, Mani N, Pattee PA, Wilkinson BJ, Jayaswal RK	J Bacteriol	10.1128/jb.174.19.6303-6306.1992	1992	*
Pathogenicity	Comparative in vitro activities of a new quinolone, OPC-17116, possessing potent activity against gram-positive bacteria.	Wakebe H, Mitsuhashi S	Antimicrob Agents Chemother	10.1128/AAC.36.10.2185	1992	*
Metabolism	Mapping and characterization of multiple chromosomal factors involved in methicillin resistance in Staphylococcus aureus.	Berger-Bachi B, Strassle A, Gustafson JE, Kayser FH	Antimicrob Agents Chemother	10.1128/AAC.36.7.1367	1992	*
Metabolism	Proline transport in Staphylococcus aureus: a high-affinity system and a low-affinity system involved in osmoregulation.	Townsend DE, Wilkinson BJ	J Bacteriol	10.1128/jb.174.8.2702-2710.1992	1992	*
Enzymology	Mechanisms of clinical resistance to fluoroquinolones in Staphylococcus aureus.	Nakanishi N, Yoshida S, Wakebe H, Inoue M, Yamaguchi T, Mitsuhashi S	Antimicrob Agents Chemother	10.1128/AAC.35.12.2562	1991	*
Genetics	Transformation of a conditionally peptidoglycan-deficient mutant of Staphylococcus aureus with plasmid DNA.	Nieuwlandt DT, Pattee PA	J Bacteriol	10.1128/jb.171.9.4906-4913.1989	1989	*
Enzymology	Construction, transfer and properties of a novel temperature-sensitive integrable plasmid for genomic analysis of Staphylococcus aureus.	Luchansky JB, Benson AK, Atherly AG	Mol Microbiol	10.1111/j.1365-2958.1989.tb00105.x	1989	*
Cultivation	[Bacteriophage conversion as a factor modifying the intensity of phagocytosis of Staphylococcus aureus by human leukocytes].	Mlynarczyk G, Garlinski P, Mlynarczyk A, Zabuska K, Sawicka-Grzelak A, Machowska G, Osowiecki H, Roszkowski W	Med Dosw Mikrobiol		1989	*
Enzymology	Specific attachment of Staphylococcus aureus to immobilized fibronectin.	Maxe I, Ryden C, Wadstrom T, Rubin K	Infect Immun	10.1128/iai.54.3.695-704.1986	1986	*
Enzymology	Chromosomal map location of the alpha-hemolysin structural gene in Staphylococcus aureus NCTC 8325.	Pattee PA	Infect Immun	10.1128/iai.54.2.593-596.1986	1986	*
Metabolism	Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.	Tam JE, Pattee PA	J Bacteriol	10.1128/jb.168.2.708-714.1986	1986	*
Enzymology	Virulence of Staphylococcus aureus in a mouse mastitis model: studies of alpha hemolysin, coagulase, and protein A as possible virulence determinants with protoplast fusion and gene cloning.	Jonsson P, Lindberg M, Haraldsson I, Wadstrom T	Infect Immun	10.1128/iai.49.3.765-769.1985	1985	*
Pathogenicity	Some effects of plasmids coding for antibiotic resistance on the virulence of Staphylococcus aureus.	Kinsman OS, Naidoo J, Noble WC	Br J Exp Pathol		1985	*
Genetics	Isolation of transposon Tn551 insertions near chromosomal markers of interest in Staphylococcus aureus.	Luchansky JB, Pattee PA	J Bacteriol	10.1128/jb.159.3.894-899.1984	1984	*
Enzymology	The effect of membrane-bound beta-lactamase on linoleic acid sensitivity in Staphylococcus aureus.	Greenway DL, Dyke KG	J Gen Microbiol	10.1099/00221287-129-8-2457	1983	*
Genetics	Plasmid replication in a temperature-sensitive chromosome replication mutant of Staphylococcus aureus.	Summers DK, Dyke KG	J Gen Microbiol	10.1099/00221287-129-7-2251	1983	*
Stress	Characterization of a temperature-sensitive DNA replication mutant of Staphylococcus aureus.	Summers DK, Dyke KG	J Gen Microbiol	10.1099/00221287-128-8-1735	1982	*
Biotechnology	Chromosomal mapping of a gene affecting enterotoxin A production in Staphylococcus aureus.	Mallonee DH, Glatz BA, Pattee PA	Appl Environ Microbiol	10.1128/aem.43.2.397-402.1982	1982	*
Pathogenicity	Identification of a chromosomal determinant of alpha-toxin production in Staphylococcus aureus.	Brown DR, Pattee PA	Infect Immun	10.1128/iai.30.1.36-42.1980	1980	*
Metabolism	Effect of thymidine auxotrophy, thymidine starvation and nalidixic acid inhibition on the properties of DNA labelled by a pulse of [3H]thymidine in Staphylococcus aureus.	Thomas CM, Dyke KG	J Gen Microbiol	10.1099/00221287-120-1-161	1980	*
Phylogeny	Isolation and properties of a linoleic acid-resistant mutant of Staphylococcus aureus.	Greenway DL, Dyke KG	J Gen Microbiol	10.1099/00221287-118-1-267	1980	*
Biotechnology	Identification of a chromosomal determinant of enterotoxin A production in Staphylococcus aureus.	Pattee PA, Glatz BA	Appl Environ Microbiol	10.1128/aem.39.1.186-193.1980	1980	*
Pathogenicity	Mechanism of the inhibitory action of linoleic acid on the growth of Staphylococcus aureus.	Greenway DL, Dyke KG	J Gen Microbiol	10.1099/00221287-115-1-233	1979	*
Metabolism	Two restriction and modification systems in Staphylococcus aureus NCTC8325.	Iordanescu S, Surdeanu M	J Gen Microbiol	10.1099/00221287-96-2-277	1976	*
Metabolism	Effect of the prophage and penicillinase plasmid of the recipient strain upon the transduction and the stability of methicillin resistance in Staphylococcus aureus.	Cohen S, Sweeney HM	J Bacteriol	10.1128/jb.116.2.803-811.1973	1973	*
Phylogeny	Isolation of a suppressor host bacterium in Staphylococcus aureus.	Kretschmer PJ, Egan JB	J Bacteriol	10.1128/jb.116.1.84-87.1973	1973	*
Pathogenicity	Berberine at sub-inhibitory concentration inhibits biofilm dispersal in Staphylococcus aureus.	Zhang C, Li Z, Pan Q, Fan L, Pan T, Zhu F, Pan Q, Shan L, Zhao L	Microbiology (Reading)	10.1099/mic.0.001243	2022	*
Metabolism	Discovery of an L-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism.	Pederick JL, Horsfall AJ, Jovcevski B, Klose J, Abell AD, Pukala TL, Bruning JB	J Biol Chem	10.1016/j.jbc.2022.102392	2022	*
Metabolism	Identification of responsible amino acid residues in staphylococcal superantigen-like 12 for the activation of mast cells.	Kim G, Itoh S, Ito Y, Ohya S, Hida S	Genes Cells	10.1111/gtc.12973	2022	*
	Lipoproteins Cause Bone Resorption in a Mouse Model of Staphylococcus aureus Septic Arthritis.	Schultz M, Mohammad M, Nguyen MT, Hu Z, Jarneborn A, Wienken CM, Froning M, Pullerits R, Ali A, Hayen H, Gotz F, Jin T	Front Microbiol	10.3389/fmicb.2022.843799	2022	*
	Sponge-associated sp. RM66 metabolome induction with N-acetylglucosamine: Antibacterial, antifungal and anti-trypanosomal activities.	Alkhalifah DHM	Saudi J Biol Sci	10.1016/j.sjbs.2021.04.082	2021	*
	Prostaglandin E2 promotes Staphylococcus aureus infection via EP4 receptor in bovine endometrium.	Liu K, Mao W, Liu B, Li T, Wang X, Pei L, Cao J, Wang F	Microb Pathog	10.1016/j.micpath.2021.105019	2021	*
	Effectiveness of topical adjuvants in reducing biofilm formation on orthopedic implants: an in vitro analysis.	Kia C, Cusano A, Messina J, Muench LN, Chadayammuri V, McCarthy MB, Umejiego E, Mazzocca AD	J Shoulder Elbow Surg	10.1016/j.jse.2020.12.009	2021	*
	Assessment of Bona Fide sRNAs in Staphylococcus aureus.	Liu W, Rochat T, Toffano-Nioche C, Le Lam TN, Bouloc P, Morvan C	Front Microbiol	10.3389/fmicb.2018.00228	2018	*
	Does Treatment Order Matter? Investigating the Ability of Bacteriophage to Augment Antibiotic Activity against Staphylococcus aureus Biofilms.	Kumaran D, Taha M, Yi Q, Ramirez-Arcos S, Diallo JS, Carli A, Abdelbary H	Front Microbiol	10.3389/fmicb.2018.00127	2018	*
	Rifampicin-Manuka Honey Combinations Are Superior to Other Antibiotic-Manuka Honey Combinations in Eradicating Staphylococcus aureus Biofilms.	Liu MY, Cokcetin NN, Lu J, Turnbull L, Carter DA, Whitchurch CB, Harry EJ	Front Microbiol	10.3389/fmicb.2017.02653	2018	*
	Surface proteins and the formation of biofilms by Staphylococcus aureus.	Kim SJ, Chang J, Rimal B, Yang H, Schaefer J	Biochim Biophys Acta Biomembr	10.1016/j.bbamem.2017.12.003	2017	*
	Prediction driven functional annotation of hypothetical proteins in the major facilitator superfamily of S. aureus NCTC 8325.	Marklevitz J, Harris LK	Bioinformation	10.6026/97320630012254	2016	*
	Predictive characterization of hypothetical proteins in Staphylococcus aureus NCTC 8325.	School K, Marklevitz J, K Schram W, K Harris L	Bioinformation	10.6026/97320630012209	2016	*
	In Vitro Activities of Nisin and Nisin Derivatives Alone and In Combination with Antibiotics against Staphylococcus Biofilms.	Field D, O' Connor R, Cotter PD, Ross RP, Hill C	Front Microbiol	10.3389/fmicb.2016.00508	2016	*
	Evaluation of adhesion forces of Staphylococcus aureus along the length of Candida albicans hyphae.	Ovchinnikova ES, Krom BP, Busscher HJ, van der Mei HC	BMC Microbiol	10.1186/1471-2180-12-281	2012	*
	Mutation of sarA in Staphylococcus aureus limits biofilm formation.	Beenken KE, Blevins JS, Smeltzer MS	Infect Immun	10.1128/IAI.71.7.4206-4211.2003	2003	*
	Vaccination against Staphylococcus aureus mastitis: immunological response of mice vaccinated with fibronectin-binding protein (FnBP-A) to challenge with S. aureus.	Mamo W, Jonsson P, Flock JI, Lindberg M, Muller HP, Wadstrom T, Nelson L	Vaccine	10.1016/0264-410x(94)90333-6	1994	*
	Confirmation of protoplast fusion-derived linkages in Staphylococcus aureus by transformation with protoplast DNA.	Stahl ML, Pattee PA	J Bacteriol	10.1128/jb.154.1.406-412.1983	1983	*
	Computer-assisted chromosome mapping by protoplast fusion in Staphylococcus aureus.	Stahl ML, Pattee PA	J Bacteriol	10.1128/jb.154.1.395-405.1983	1983	*
	Transduction of Methicillin Resistance in Staphylococcus aureus Dependent on an Unusual Specificity of the Recipient Strain.	Cohen S, Sweeney HM	J Bacteriol	10.1128/jb.104.3.1158-1167.1970	1970	*
	Evaluation of the Effect of Leaf Development in Plectranthus amboinicus L. on Antimicrobial Activity and Virulence Factors of Pseudomonas aeruginosa PAO1 and Staphylococcus aureus NCTC8325.	Sawant S, Baldwin TC, Khan H, Rahman A	Curr Microbiol	10.1007/s00284-022-03126-7	2022	*
	Impact of Environmental Conditions on the Protein Content of Staphylococcus aureus and Its Derived Extracellular Vesicles.	da Luz BSR, de Rezende Rodovalho V, Nicolas A, Chabelskaya S, Jardin J, Briard-Bion V, Le Loir Y, de Carvalho Azevedo VA, Guedon E	Microorganisms	10.3390/microorganisms10091808	2022	*

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Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.: List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ. IJSEM ( DOI 10.1099/ijsem.0.004332 )

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Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Automatically annotated for the DiASPora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

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Antje Chang, Lisa Jeske, Sandra Ulbrich, Julia Hofmann, Julia Koblitz, Ida Schomburg, Meina Neumann-Schaal, Dieter Jahn, Dietmar Schomburg: BRENDA, the ELIXIR core data resource in 2021: new developments and updates. Nucleic Acids Res. 49: D498 - D508 2020 ( DOI 10.1093/nar/gkaa1025 , PubMed 33211880 )

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Julia Koblitz, Joaquim Sardà, Lorenz Christian Reimer, Boyke Bunk, Jörg Overmann: Predictions based on genome sequence made in the Diaspora project (Digital Approaches for the Synthesis of Poorly Accessible Biodiversity Information) .

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Xiao-Yin To, René Mreches, Martin Binder, Alice C. McHardy, Philipp C. Münch: Predictions based on the model GenomeNet Sporulation v. 1 . ( DOI 10.21203/rs.3.rs-2527258/v1 )

#83594

Reimer, L.C., Lissin, A.,Schober, I., Witte,J.F., Podstawka, A., Lüken, H., Bunk, B.,Overmann, J.: StrainInfo: A central database for resolving microbial strain identifiers . ( DOI 10.60712/SI-ID28647.1 )

#116610 Collection of Institut Pasteur ; Curators of the CIP; CIP 107700
* These data were automatically processed and therefore are not curated

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Search for species Staphylococcus aureus in external resources:
SILVA
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PANGAEA
StrainInfo
GBIF

Staphylococcus aureus subsp. aureus NCTC 8325 NCTC 8325

Staphylococcus aureus subsp. aureus NCTC 8325 NCTC 8325

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Change proposal