Cutibacterium acnes | Type strain | DSM 1897, ATCC 6919, CCUG 1794, JCM 6425, KCTC 3314, NCTC 737

Strain identifier

BacDive ID: 12636

Type strain:

Species: Cutibacterium acnes

Culture col. no.: DSM 1897, ATCC 6919, CCUG 1794, JCM 6425, KCTC 3314, NCTC 737

Section

Name and taxonomic classification
Morphology and physiology
Culture and growth conditions
Isolation, sampling and environmental information
Application and interaction
Molecular biology
Strain availability

External links

Information on the name and the taxonomic classification.Name and taxonomic classification

[Ref.: #919]	Domain	Bacteria
[Ref.: #919]	Phylum	Actinobacteria
[Ref.: #919]	Class	Actinobacteria
[Ref.: #919]	Order	Actinomycetales
[Ref.: #919]	Family	Propionibacteriaceae
[Ref.: #919]	Genus	Cutibacterium
[Ref.: #919]	Species	Cutibacterium acnes
[Ref.: #919]	Full Scientific Name	Propionibacterium acnes (Gilchrist 1900) Douglas and Gunter 1946
[Ref.: #919]	Type strain

		Prokaryotic Nomenclature Up-to-date (PNU)	Taxonomical status	Literature reference
[Ref.: #20215]	Domain	Bacteria
[Ref.: #20215]	Phylum	Actinobacteria
[Ref.: #20215]	Class	Actinobacteria		Int. J. Syst. Bacteriol. 47:483*
[Ref.: #20215]	Family	Propionibacteriaceae		Int. J. Syst. Bacteriol. 30:237
[Ref.: #20215]	Genus	Cutibacterium	gen. nov. (VP)	Int. J. Syst. Evol. Microbiol. 66:4430*
[Ref.: #20215]	Species	Cutibacterium acnes	comb. nov. (VP)	Int. J. Syst. Evol. Microbiol. 66:4430*
[Ref.: #20215]	Full Scientific Name	Cutibacterium acnes (Gilchrist 1900) Scholz and Kilian 2016

[Ref.: #20215]	Synonym	Propionibacterium acnes
[Ref.: #20215]	Synonym	Propionibacterium acnes subsp. acnes
[Ref.: #20215]	Synonym	Propionibacterium acnes subsp. elongatum

Information on morphological and physiological propertiesMorphology and physiology

[Ref.: #24963]	Gram stain	positive
[Ref.: #24963]	Cell length	0.8-0.9 µm
[Ref.: #24963]	Cell width	0.4-0.5 µm
[Ref.: #24963]	Cell shape	rod-shaped
[Ref.: #24963]	Motility	no

[Ref.: #24963]	Cell shape	ellipsoidal

[Ref.: #24963]	Type of hemolysis	beta
[Ref.: #24963]	Colony size	<4.0 mm
[Ref.: #24963]	Colony color	white,tan, pink or orange
[Ref.: #24963]	Incubation period	21 days

[Ref.: #24963]	Type of hemolysis	beta
[Ref.: #24963]	Colony size	<5.0 mm
[Ref.: #24963]	Colony color	white-to-gray
[Ref.: #24963]	Colony shape	circular
[Ref.: #24963]	Cultivation medium used	blood agar (horse or rabbit)

[Ref.: #919]

Name of produced compound

LL diaminopimelic acid

	Enzyme	Enzyme activity	EC number
[Ref.: #24963]	acid phosphatase	+	3.1.3.2
[Ref.: #24963]	catalase	+	1.11.1.6
[Ref.: #24963]	hyaluronidase	+	3.2.1.35
[Ref.: #24963]	lecithinase	+
[Ref.: #24963]	lipase	+
[Ref.: #24963]	neuramindase	+	3.2.1.18
[Ref.: #24963]	pyrrolidonyl arylamidase	+	3.4.19.3
[Ref.: #24963]	ribonuclease	+	2.7.7.16

API® rID32A:

Note that the displayed test results represent raw data and therefore may deviate!

	API ID	Urease/urea hydrolysisURE	Arginine dihydrolaseADH (Arg)	alpha-Galactosidasealpha GAL	beta-Galactosidasebeta GAL	beta-Galactosidase 6-phosphatebeta GP	alpha-Glucosidasealpha GLU	beta-Glucosidasebeta GLU	alpha-Arabinosidasealpha ARA	beta-Glucuronidasebeta GUR	beta-N-Acetyl-beta-glucosaminidasebeta NAG	Fermentation of D-mannoseMNE	Fermentation of raffinoseRAF	Glutamate decarboxylaseGDC	alpha-Fucosidasealpha FUC	Reduction of nitrateNIT	Indole productionIND	Alkaline phosphatasePAL	L-arginine arylamidaseArgA	Proline arylamidaseProA	Leucyl glycin arylamidaseLGA	Phenylalanine arylamidasePheA	Leucine arylamidaseLeuA	Pyrrolidonyl arylamidasePyrA	Tyrosine arylamidaseTyrA	Alanine arylamidaseAlaA	Glycin arylamidaseGlyA	Histidine arylamidaseHisA	Glutamyl-glutamate arylamidaseGGA	Serine arylamidaseSerA
[Ref.: #919]	2732	-	+	-	+	-	-	-	-	-	+	-	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	-
[Ref.: #919]	2345	-	+	-	+/-	-	-	-	-	-	+	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2344	-	+	-	+	-	-	-	-	-	+	+	-	-	-	-	+	-	+/-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2343	-	-	-	+	-	-	-	-	-	+/-	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2342	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	+	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2341	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+/-	+	-	-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2340	-	+	-	+	-	-	-	-	-	+/-	+	-	-	-	+	+	-	+/-	+	-	-	-	-	-	+	+	-	-	+
[Ref.: #919]	2795	-	+	-	+	-	-	-	-	-	+	+	-	-	-	+	+	-	-	+	-	-	-	-	-	+	+	-	-	+

	Metabolite production	Metabolite	Production
[Ref.: #24963]		Indole	yes

	Metabolite	Utilization activity	Kind of utilization tested
[Ref.: #24963]	Esculin	-	hydrolysis
[Ref.: #24963]	Gelatin	+	hydrolysis
[Ref.: #24963]	Glucose	+	fermentation
[Ref.: #24963]	Glycerol	+	fermentation
[Ref.: #24963]	Maltose	-	fermentation
[Ref.: #24963]	Nitrate	+	reduction
[Ref.: #24963]	Ribose	-	fermentation
[Ref.: #24963]	Sorbitol	+	fermentation
[Ref.: #24963]	Sucrose	-	fermentation

[Ref.: #919]	Murein short key	A41.01
[Ref.: #919]	Murein types	A3gamma LL-Dpm-Gly

[Ref.: #919]	Oxygen tolerance	anaerobe
[Ref.: #24963]	Oxygen tolerance	anaerobe
[Ref.: #24963]	Oxygen tolerance	aerotolerant

[Ref.: #24963]

Ability of spore formation

Information on culture and growth conditionsCulture and growth conditions

[Ref.: #919]

Culture medium

CHOPPED MEAT MEDIUM (DSMZ Medium 78), 37°C, anaerobic

[Ref.: #919]

Culture medium growth

[Ref.: #919]

Culture medium link

medium recipe provided by DSMZ

[Ref.: #24963]

Culture medium

blood agar (horse or rabbit)

[Ref.: #24963]

Culture medium growth

[Ref.: #42199]

Culture medium

MEDIUM 20 - for Anaerobic bacteria

[Ref.: #42199]

Culture medium growth

[Ref.: #42199]

Culture medium composition

expand / minimize

		Temperature
[Ref.: #919]	growth	37 ̊C
[Ref.: #24963]	optimum	30.0-37.0 ̊C
[Ref.: #42199]	growth	37 ̊C

[Ref.: #919]

Temperature range

mesophilic

	pH	Kind of pH		pH
[Ref.: #24963]			maximum	4.5-5.0

Information on isolation source, the sampling and environmental conditionsIsolation, sampling and environmental information

[Ref.: #919]

Sample type/isolated from

acne lesion in human facial skin

[Ref.: #24963]

Sample type/isolated from

facial acne

[Ref.: #24963]

Geographic location (country and/or sea, region)

London

[Ref.: #24963]

Country

United Kingdom

[Ref.: #24963]

Continent

Europe

Isolation sources categories

#Host-associates	#Human	-
#Medical	#Inflammation	-
#Host Body-Site	#Organ	#Skin, Nail, Hair

What are isolation sources categories?

* marker position based on {}

Information on possible application of the strain and its possible interaction with e.g. potential hostsApplication and interaction

[Ref.: #919]

Biosafety level

Risk group (German classification)

Information on genomic background e.g. entries in nucleic sequence databassMolecular biology

[Ref.: #919]	GC-content	59.0 mol%
[Ref.: #24963]	GC-content	60 mol%	genome sequence analysis

Sequence information:

Only first 5 entries are displayed. Click here to see all.

	Sequence database	Sequence accession description	Sequence accession number	Sequence length (bp)	Associated NCBI tax ID
[Ref.: #20218]	Marker Gene (DDBJ Direct submission)	Propionibacterium acnes DNA, 16S-23S ribosomal RNA intergenic spacer region, strain: ATCC 6919	AB108459	222	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes camp factor-1 (Camp-1) gene, complete cds	AY527218	858	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes putative hemolysin (tlyA) gene, complete cds	AY527219	777	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes Camp2 gene, complete cds	AY726656	804	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes Camp3 gene, complete cds	AY726657	816	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes Camp4 gene, partial cds	AY726658	786	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes Camp5 gene, complete cds	AY726659	846	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes iron-binding surface protein (PA21693) gene, complete cds	DQ469870	1404	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes HtaA-like surface protein (PA4687) gene, complete cds	DQ469871	1572	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes HmuT-like heme-binding lipoprotein (PA21740) gene, complete cds	DQ469872	1320	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes host cell-surface attachment protein PA25957 (PA25957) gene, complete cds	DQ469873	1299	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes dermatan-binding protein PA5541 (PA5541) gene, complete cds	DQ469874	1335	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes hemin ABC transporter system permease gene, complete cds	DQ767876	1062	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes hemin ABC transporter system ATP binding protein (PA21788) gene, complete cds	DQ767877	780	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes ATCC 6919 16S rRNA gene, partial sequence	U02904	387	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain CCUG 1794 clone 1 16S-23S ribosomal RNA intergenic spacer, partial sequence	GQ496473	222	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain DSM 1897 16S ribosomal RNA gene, partial sequence	EF680378	451	1747	*
[Ref.: #20218]	Marker Gene (EMBL Direct submission)	Propionibacterium acnes partial 16S rRNA	X53218	1359	1747	*
[Ref.: #20218]	Marker Gene (DDBJ Direct submission)	Propionibacterium acnes gnpA gene for galacto-N-biose phosphorylase, complete cds, strain: JCM 6425	AB468066	2331	1747	*
[Ref.: #20218]	Marker Gene (DDBJ Direct submission)	Propionibacterium acnes gene for 16S ribosomal RNA, partial sequence, strain: JCM 6425	AB538431	1486	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC 737 RecA (recA) gene, complete cds	AY642055	1047	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 superoxide dismutase (sodA) gene, sodA-1 allele, partial cds	HQ283900	450	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 ATP synthase beta chain (atpD) gene, atpD-1 allele, partial cds	HQ908364	453	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 shikimate 5-dehydrogenase (aroE) gene, partial cds	JF789639	424	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 GTP-binding protein (lepA) gene, partial cds	JF789652	452	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 guanylate kinase (gmk) gene, partial cds	JF789659	400	1747	*
[Ref.: #20218]	Marker Gene (GenBank Direct submission)	Propionibacterium acnes strain NCTC737 GMP synthase (guaA) gene, partial cds	JF789667	493	1747	*
[Ref.: #919]	INSDC (WGS)	Cutibacterium acnes DSM 1897, whole genome shotgun sequencing project	AWZZ00000000	10	1122995
[Ref.: #919]	DDBJ EMBL Direct submission		AB042288

Availability in culture collectionsStrain availability

[Ref.: #919]

Culture collection no.

DSM 1897, ATCC 6919, CCUG 1794, JCM 6425, KCTC 3314, NCTC 737

[Ref.: #919]

Strain history

<- ATCC <- NCTC <- A. Hayden (Corynebacterium acnes)

[Ref.: #20218]

Associated Passport(s) in StrainInfo

16391, 16387, 16389, 16393, 314876, 16395

References

#919	Leibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH ; Curators of the DSMZ; DSM 1897

#20215

Leibniz Institute DSMZ D.Gleim, M.Kracht, N.Weiss et. al.: Prokaryotic Nomenclature Up-to-date - compilation of all names of Bacteria and Archaea, validly published according to the Bacteriological Code since 1. Jan. 1980, and validly published nomenclatural changes since .

#20218

Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.: StrainInfo introduces electronic passports for microorganisms.. Syst Appl Microbiol. 37: 42 - 50 2014 ( DOI 10.1016/j.syapm.2013.11.002 , PubMed 24321274 )

#24963

C. F. P. K. Scholz, Mogens: The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov.. IJSEM 66: 4422 - 4432 2016 ( DOI 10.1099/ijsem.0.001367 )

#42199 ; Curators of the CIP;
* These References are textmined

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