Enzymology |
Immunotopological Analysis of the Treponema denticola Major Surface Protein (Msp). |
Godovikova V, Goetting-Minesky MP, Timm JC, Fenno JC |
J Bacteriol |
10.1128/JB.00528-18 |
2018 |
* |
Pathogenicity |
Treponema denticola Induces Epithelial Barrier Dysfunction in Polarized Epithelial Cells. |
Kikuchi Y, Kimizuka R, Kato T, Okuda K, Kokubu E, Ishihara K |
Bull Tokyo Dent Coll |
10.2209/tdcpublication.2017-0052 |
2018 |
* |
Phylogeny |
Oral treponeme major surface protein: Sequence diversity and distributions within periodontal niches. |
You M, Chan Y, Lacap-Bugler DC, Huo YB, Gao W, Leung WK, Watt RM |
Mol Oral Microbiol |
10.1111/omi.12185 |
2017 |
* |
Metabolism |
Comparative analysis of motility and other properties of Treponema denticola strains. |
Nagano K, Hasegawa Y, Yoshida Y, Yoshimura F |
Microb Pathog |
10.1016/j.micpath.2016.11.021 |
2016 |
* |
Enzymology |
Characterization of a potential ABC-type bacteriocin exporter protein from Treponema denticola. |
Tanaka-Kumazawa K, Kikuchi Y, Sano-Kokubun Y, Shintani S, Yakushiji M, Kuramitsu HK, Ishihara K |
BMC Oral Health |
10.1186/s12903-016-0243-7 |
2016 |
* |
Pathogenicity |
A Modified Shuttle Plasmid Facilitates Expression of a Flavin Mononucleotide-Based Fluorescent Protein in Treponema denticola ATCC 35405. |
Godovikova V, Goetting-Minesky MP, Shin JM, Kapila YL, Rickard AH, Fenno JC |
Appl Environ Microbiol |
10.1128/AEM.01541-15 |
2015 |
* |
Metabolism |
Dentilisin involvement in coaggregation between Treponema denticola and Tannerella forsythia. |
Sano Y, Okamoto-Shibayama K, Tanaka K, Ito R, Shintani S, Yakushiji M, Ishihara K |
Anaerobe |
10.1016/j.anaerobe.2014.08.008 |
2014 |
* |
Enzymology |
Conservation and revised annotation of the Treponema denticola prcB-prcA-prtP locus encoding the dentilisin (CTLP) protease complex. |
Goetting-Minesky MP, Godovikova V, Li JJ, Seshadrinathan S, Timm JC, Kamodia SS, Fenno JC |
Mol Oral Microbiol |
10.1111/omi.12013 |
2012 |
* |
Enzymology |
Disruption of a type II endonuclease (TDE0911) enables Treponema denticola ATCC 35405 to accept an unmethylated shuttle vector. |
Bian J, Li C |
Appl Environ Microbiol |
10.1128/AEM.00417-11 |
2011 |
* |
Pathogenicity |
Mixture of periodontopathogenic bacteria influences interaction with KB cells. |
Kirschbaum M, Schultze-Mosgau S, Pfister W, Eick S |
Anaerobe |
10.1016/j.anaerobe.2010.03.009 |
2010 |
* |
Enzymology |
Human serum antibodies recognize Treponema denticola Msp and PrtP protease complex proteins. |
Capone R, Wang HT, Ning Y, Sweier DG, Lopatin DE, Fenno JC |
Oral Microbiol Immunol |
10.1111/j.1399-302X.2007.00404.x |
2008 |
* |
Metabolism |
Steroid 5alpha-reductase activity of Treponema denticola. |
Clark DT, Soory M |
Oral Microbiol Immunol |
10.1111/j.1399-302X.2007.00364.x |
2007 |
* |
Metabolism |
The chymotrypsin-like protease complex of Treponema denticola ATCC 35405 mediates fibrinogen adherence and degradation. |
Bamford CV, Fenno JC, Jenkinson HF, Dymock D |
Infect Immun |
10.1128/IAI.00258-07 |
2007 |
* |
Pathogenicity |
Treponema denticola induces interleukin-8 and macrophage chemoattractant protein 1 production in human umbilical vein epithelial cells. |
Okuda T, Kimizuka R, Miyamoto M, Kato T, Yamada S, Okuda K, Ishihara K |
Microbes Infect |
10.1016/j.micinf.2007.03.009 |
2007 |
* |
Metabolism |
Characterization of Treponema denticola pyrF encoding orotidine-5'-monophosphate decarboxylase. |
Capone RF, Ning Y, Pakulis N, Alhazzazi T, Fenno JC |
FEMS Microbiol Lett |
10.1111/j.1574-6968.2006.00589.x |
2006 |
* |
Metabolism |
Surface protease of Treponema denticola hydrolyzes C3 and influences function of polymorphonuclear leukocytes. |
Yamazaki T, Miyamoto M, Yamada S, Okuda K, Ishihara K |
Microbes Infect |
10.1016/j.micinf.2006.02.013 |
2006 |
* |
Metabolism |
Binding properties and adhesion-mediating regions of the major sheath protein of Treponema denticola ATCC 35405. |
Edwards AM, Jenkinson HF, Woodward MJ, Dymock D |
Infect Immun |
10.1128/IAI.73.5.2891-2898.2005 |
2005 |
* |
Metabolism |
Multiple functions of the leucine-rich repeat protein LrrA of Treponema denticola. |
Ikegami A, Honma K, Sharma A, Kuramitsu HK |
Infect Immun |
10.1128/IAI.72.8.4619-4627.2004 |
2004 |
* |
Metabolism |
Genetic analysis of Treponema denticola ATCC 35405 biofilm formation. |
Vesey PM, Kuramitsu HK |
Microbiology (Reading) |
10.1099/mic.0.26816-0 |
2004 |
* |
Metabolism |
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes. |
Seshadri R, Myers GS, Tettelin H, Eisen JA, Heidelberg JF, Dodson RJ, Davidsen TM, DeBoy RT, Fouts DE, Haft DH, Selengut J, Ren Q, Brinkac LM, Madupu R, Kolonay J, Durkin SA, Daugherty SC, Shetty J, Shvartsbeyn A, Gebregeorgis E, Geer K, Tsegaye G, Malek J, Ayodeji B, Shatsman S, McLeod MP, Smajs D, Howell JK, Pal S, Amin A, Vashisth P, McNeill TZ, Xiang Q, Sodergren E, Baca E, Weinstock GM, Norris SJ, Fraser CM, Paulsen IT |
Proc Natl Acad Sci U S A |
10.1073/pnas.0307639101 |
2004 |
* |
Phylogeny |
Genetic relatedness and phenotypic characteristics of Treponema associated with human periodontal tissues and ruminant foot disease. |
Edwards AM, Dymock D, Woodward MJ, Jenkinson HF |
Microbiology (Reading) |
10.1099/mic.0.26111-0 |
2003 |
* |
Pathogenicity |
Treponema denticola may stimulate both epithelial proliferation and apoptosis through MAP kinase signal pathways. |
Leung WK, Wu Q, Hannam PM, McBride BC, Uitto VJ |
J Periodontal Res |
10.1034/j.1600-0765.2002.01007.x |
2002 |
* |
Pathogenicity |
Motility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticola. |
Lux R, Miller JN, Park NH, Shi W |
Infect Immun |
10.1128/IAI.69.10.6276-6283.2001 |
2001 |
* |
Pathogenicity |
Insertional inactivation of the prtP gene of Treponema denticola confirms dentilisin's disruption of epithelial junctions. |
Ellen RP, Ko KS, Lo CM, Grove DA, Ishihara K |
J Mol Microbiol Biotechnol |
|
2000 |
* |
Metabolism |
Identification of a Treponema denticola OppA homologue that binds host proteins present in the subgingival environment. |
Fenno JC, Tamura M, Hannam PM, Wong GW, Chan RA, McBride BC |
Infect Immun |
10.1128/IAI.68.4.1884-1892.2000 |
2000 |
* |
Pathogenicity |
Molecular characterization of a flagellar (fla) operon in the oral spirochete Treponema denticola ATCC 35405. |
Stamm LV, Bergen HL |
FEMS Microbiol Lett |
10.1111/j.1574-6968.1999.tb08703.x |
1999 |
* |
Phylogeny |
Mitogenic activity of the outer membrane of Treponema denticola. |
Schade SZ, Yotis WW, Gopalsami C, Simonson LG |
Microbios |
|
1998 |
* |
Metabolism |
Oxygen metabolism by Treponema denticola. |
Caldwell CE, Marquis RE |
Oral Microbiol Immunol |
10.1034/j.1399-302x.1999.140109.x |
1999 |
* |
Metabolism |
Treponema denticola outer membrane enhances the phagocytosis of collagen-coated beads by gingival fibroblasts. |
Battikhi T, Lee W, McCulloch CA, Ellen RP |
Infect Immun |
10.1128/IAI.67.3.1220-1226.1999 |
1999 |
* |
Pathogenicity |
Characterization of a novel methyl-accepting chemotaxis gene, dmcB, from the oral spirochete Treponema denticola. |
Li H, Arakawa S, Deng QD, Kuramitsu H |
Infect Immun |
10.1128/IAI.67.2.694-699.1999 |
1999 |
* |
Enzymology |
Mutagenesis of outer membrane virulence determinants of the oral spirochete Treponema denticola. |
Fenno JC, Wong GW, Hannam PM, McBride BC |
FEMS Microbiol Lett |
10.1111/j.1574-6968.1998.tb13047.x |
1998 |
* |
Metabolism |
Filamentous actin disruption and diminished inositol phosphate response in gingival fibroblasts caused by Treponema denticola. |
Yang PF, Song M, Grove DA, Ellen RP |
Infect Immun |
10.1128/IAI.66.2.696-702.1998 |
1998 |
* |
Enzymology |
Identification, isolation, and characterization of the 42-kilodalton major outer membrane protein (MompA) from Treponema pectinovorum ATCC 33768. |
Walker SG, Ebersole JL, Holt SC |
J Bacteriol |
10.1128/jb.179.20.6441-6447.1997 |
1997 |
* |
Genetics |
Characterization of a methyl-accepting chemotaxis protein gene, dmcA, from the oral spirochete Treponema denticola. |
Kataoka M, Li H, Arakawa S, Kuramitsu H |
Infect Immun |
10.1128/iai.65.10.4011-4016.1997 |
1997 |
* |
Pathogenicity |
Genetic and transcriptional analysis of flgB flagellar operon constituents in the oral spirochete Treponema denticola and their heterologous expression in enteric bacteria. |
Heinzerling HF, Olivares M, Burne RA |
Infect Immun |
10.1128/iai.65.6.2041-2051.1997 |
1997 |
* |
Metabolism |
Visualization of an extracellular mucoid layer of Treponema denticola ATCC 35405 and surface sugar lectin analysis of some Treponema species. |
Scott D, Klitorinos A, Chan EC, Siboo R |
Oral Microbiol Immunol |
10.1111/j.1399-302x.1997.tb00628.x |
1997 |
* |
Genetics |
Conservation of msp, the gene encoding the major outer membrane protein of oral Treponema spp. |
Fenno JC, Wong GW, Hannam PM, Muller KH, Leung WK, McBride BC |
J Bacteriol |
10.1128/jb.179.4.1082-1089.1997 |
1997 |
* |
Enzymology |
gamma-Glutamyltransferase from the outer cell envelope of Treponema denticola ATCC 35405. |
Makinen PL, Makinen KK |
Infect Immun |
10.1128/iai.65.2.685-691.1997 |
1997 |
* |
Enzymology |
Characterization of the Treponema denticola prtP gene encoding a prolyl-phenylalanine-specific protease (dentilisin). |
Ishihara K, Miura T, Kuramitsu HK, Okuda K |
Infect Immun |
10.1128/iai.64.12.5178-5186.1996 |
1996 |
* |
Enzymology |
Iron acquisition by oral hemolytic spirochetes: isolation of a hemin-binding protein and identification of iron reductase activity. |
Scott D, Chan EC, Siboo R |
Can J Microbiol |
10.1139/m96-137 |
1996 |
* |
Metabolism |
The major surface protein complex of Treponema denticola depolarizes and induces ion channels in HeLa cell membranes. |
Mathers DA, Leung WK, Fenno JC, Hong Y, McBride BC |
Infect Immun |
10.1128/iai.64.8.2904-2910.1996 |
1996 |
* |
Metabolism |
Hyaluronan, a possible ligand mediating Treponema denticola binding to periodontal tissue. |
Haapasalo M, Hannam P, McBride BC, Uitto VJ |
Oral Microbiol Immunol |
10.1111/j.1399-302x.1996.tb00351.x |
1996 |
* |
Genetics |
Gene inactivation in the oral spirochete Treponema denticola: construction of an flgE mutant. |
Li H, Ruby J, Charon N, Kuramitsu H |
J Bacteriol |
10.1128/jb.178.12.3664-3667.1996 |
1996 |
* |
Metabolism |
Sequence analysis, expression, and binding activity of recombinant major outer sheath protein (Msp) of Treponema denticola. |
Fenno JC, Muller KH, McBride BC |
J Bacteriol |
10.1128/jb.178.9.2489-2497.1996 |
1996 |
* |
Enzymology |
Proline iminopeptidase from the outer cell envelope of the human oral spirochete Treponema denticola ATCC 35405. |
Makinen KK, Chen CY, Makinen PL |
Infect Immun |
10.1128/iai.64.3.702-708.1996 |
1996 |
* |
Metabolism |
Role of the chymotrypsin-like membrane-associated proteinase from Treponema denticola ATCC 35405 in inactivation of bioactive peptides. |
Makinen PL, Makinen KK, Syed SA |
Infect Immun |
10.1128/iai.63.9.3567-3575.1995 |
1995 |
* |
Pathogenicity |
Identification of a fliG homologue in Treponema denticola. |
Heinzerling HF, Penders JE, Burne RA |
Gene |
10.1016/0378-1119(95)00257-7 |
1995 |
* |
Phenotype |
Evidence for two distinct locomotory phenotypes of Treponema denticola ATCC 35405. |
Chan EC, Qiu YS, Siboo R, Noble P |
Oral Microbiol Immunol |
10.1111/j.1399-302x.1995.tb00131.x |
1995 |
* |
Enzymology |
Cloning and expression of a neutral phosphatase gene from Treponema denticola. |
Ishihara K, Kuramitsu HK |
Infect Immun |
10.1128/iai.63.4.1147-1152.1995 |
1995 |
* |
Pathogenicity |
Induction of cytoskeletal rearrangements and loss of volume regulation in epithelial cells by Treponema denticola. |
De Filippo AB, Ellen RP, McCulloch CA |
Arch Oral Biol |
10.1016/0003-9969(95)98809-d |
1995 |
* |
Enzymology |
Purification and general properties of an oligopeptidase from Treponema denticola ATCC 35405--a human oral spirochete. |
Makinen KK, Makinen PL, Loesche WJ, Syed SA |
Arch Biochem Biophys |
10.1006/abbi.1995.1092 |
1995 |
* |
Metabolism |
An endo-acting proline-specific oligopeptidase from Treponema denticola ATCC 35405: evidence of hydrolysis of human bioactive peptides. |
Makinen PL, Makinen KK, Syed SA |
Infect Immun |
10.1128/iai.62.11.4938-4947.1994 |
1994 |
* |
Enzymology |
Cloning and sequence analysis of a chymotrypsinlike protease from Treponema denticola. |
Arakawa S, Kuramitsu HK |
Infect Immun |
10.1128/iai.62.8.3424-3433.1994 |
1994 |
* |
Enzymology |
Isolation and characterization of a 53 kDa major cell envelope protein antigen from Treponema denticola ATCC 35405. |
Kokeguchi S, Miyamoto M, Kato K, Tanimoto I, Kurihara H, Murayama Y |
J Periodontal Res |
10.1111/j.1600-0765.1994.tb01093.x |
1994 |
* |
Metabolism |
Proteolytic and oxidoreductase activity of Treponema denticola ATCC 35405 grown in an aerobic and anaerobic gaseous environment. |
Syed SA, Makinen KK, Makinen PL, Chen CY, Muhammad Z |
Res Microbiol |
10.1016/0923-2508(93)90016-u |
1993 |
* |
Phylogeny |
Treponema denticola (ex Brumpt 1925) sp. nov., nom. rev., and identification of new spirochete isolates from periodontal pockets. |
Chan EC, Siboo R, Keng T, Psarra N, Hurley R, Cheng SL, Iugovaz I |
Int J Syst Bacteriol |
10.1099/00207713-43-2-196 |
1993 |
* |
Pathogenicity |
Treponema denticola induces actin rearrangement and detachment of human gingival fibroblasts. |
Baehni PC, Song M, McCulloch CA, Ellen RP |
Infect Immun |
10.1128/iai.60.8.3360-3368.1992 |
1992 |
* |
Enzymology |
Purification and substrate specificity of an endopeptidase from the human oral spirochete Treponema denticola ATCC 35405, active on furylacryloyl-Leu-Gly-Pro-Ala and bradykinin. |
Makinen KK, Makinen PL, Syed SA |
J Biol Chem |
S0021-9258(19)49710-X |
1992 |
* |
Enzymology |
Characterization, cloning, and binding properties of the major 53-kilodalton Treponema denticola surface antigen. |
Haapasalo M, Muller KH, Uitto VJ, Leung WK, McBride BC |
Infect Immun |
10.1128/iai.60.5.2058-2065.1992 |
1992 |
* |
Metabolism |
Sulfhydryl-dependent attachment of Treponema denticola to laminin and other proteins. |
Haapasalo M, Singh U, McBride BC, Uitto VJ |
Infect Immun |
10.1128/iai.59.11.4230-4237.1991 |
1991 |
* |
Enzymology |
Isolation and characterization of the Treponema denticola prtA gene coding for chymotrypsinlike protease activity and detection of a closely linked gene encoding PZ-PLGPA-hydrolyzing activity. |
Que XC, Kuramitsu HK |
Infect Immun |
10.1128/iai.58.12.4099-4105.1990 |
1990 |
* |
Enzymology |
Enzyme profiles of oral spirochetes in RapID-ANA system. |
Syed SA, Salvador SL, Loesche WJ |
J Clin Microbiol |
10.1128/jcm.26.10.2226-2228.1988 |
1988 |
* |
Enzymology |
Isolation of a chymotrypsinlike enzyme from Treponema denticola. |
Uitto VJ, Grenier D, Chan EC, McBride BC |
Infect Immun |
10.1128/iai.56.10.2717-2722.1988 |
1988 |
* |
|
Identification of protein targets in red complex organisms binding with resveratrol. |
Pothapur KK, Vishnu Priya V, Rengasamy G, Jayaseelan VP |
Bioinformation |
10.6026/97320630016837 |
2020 |
* |
|
Protein targets in the red complex organisms binding with an herbal compound silymarin. |
Faiz N, Pothapur KK, Vishnupriya V, Gayathri R, Priyadharsini JV |
Bioinformation |
10.6026/97320630016759 |
2020 |
* |
|
Identification of aspirin and diclofenac binding proteins in the red complex pathogens. |
Babu G, Priya VV, Krishnaa PK, Gayathri R, Priyadharsini JV |
Bioinformation |
10.6026/97320630017192 |
2021 |
* |
|
Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola. |
Arai Y, Kikuchi Y, Okamoto-Shibayama K, Kokubu E, Shintani S, Ishihara K |
J Oral Microbiol |
10.1080/20002297.2020.1829404 |
2020 |
* |
|
Effect of azithromycin on a red complex polymicrobial biofilm. |
Ong HS, Oettinger-Barak O, Dashper SG, Darby IB, Tan KH, Reynolds EC |
J Oral Microbiol |
10.1080/20002297.2017.1339579 |
2017 |
* |
|
Genomic and Metagenomic Analysis of Diversity-Generating Retroelements Associated with Treponema denticola. |
Nimkulrat S, Lee H, Doak TG, Ye Y |
Front Microbiol |
10.3389/fmicb.2016.00852 |
2016 |
* |
|
Kanamycin Resistance Cassette for Genetic Manipulation of Treponema denticola. |
Li Y, Ruby J, Wu H |
Appl Environ Microbiol |
10.1128/AEM.00478-15 |
2015 |
* |
|
Characterization of a Treponema denticola ATCC 35405 mutant strain with mutation accumulation, including a lack of phage-derived genes. |
Yokogawa T, Nagano K, Fujita M, Miyakawa H, Iijima M |
PLoS One |
10.1371/journal.pone.0270198 |
2022 |
* |